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Volumn 125, Issue 1, 2012, Pages 1-7

LINGO1 variants in essential tremor and Parkinson's disease

Author keywords

Disease risk; Essential tremor; Genetics; LINGO1; Parkinson's disease; Rs9652490

Indexed keywords

ALLELE; AMINO TERMINAL SEQUENCE; CARBOXY TERMINAL SEQUENCE; CHINA; ESSENTIAL TREMOR; FAMILY HISTORY; FRANCE; GENE; GENE EXPRESSION; GENE FREQUENCY; GENE FUNCTION; GENE LINKAGE DISEQUILIBRIUM; GENE STRUCTURE; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GERMANY; HUMAN; LINGO1 GENE; NONHUMAN; NORTH AMERICA; NORWAY; PARKINSON DISEASE; PATHOGENESIS; POLAND; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM; SPAIN; SUBSTANTIA NIGRA;

EID: 84155187234     PISSN: 00016314     EISSN: 16000404     Source Type: Journal    
DOI: 10.1111/j.1600-0404.2011.01516.x     Document Type: Review
Times cited : (32)

References (67)
  • 1
    • 58349109492 scopus 로고    scopus 로고
    • Prevalence of essential tremor in a multiethnic, community-based study in northern Manhattan, New York, NY
    • Louis ED, Thawani SP, Andrews HF. Prevalence of essential tremor in a multiethnic, community-based study in northern Manhattan, New York, NY. Neuroepidemiology 2009;32:208-14.
    • (2009) Neuroepidemiology , vol.32 , pp. 208-214
    • Louis, E.D.1    Thawani, S.P.2    Andrews, H.F.3
  • 2
    • 0034643838 scopus 로고    scopus 로고
    • Prevalence of Parkinson's disease in Europe: a collaborative study of population-based cohorts. Neurologic Diseases in the Elderly Research Group
    • De Rijk MC, Launer LJ, Berger K et al. Prevalence of Parkinson's disease in Europe: a collaborative study of population-based cohorts. Neurologic Diseases in the Elderly Research Group. Neurology 2000;54:S21-3.
    • (2000) Neurology , vol.54
    • De Rijk, M.C.1    Launer, L.J.2    Berger, K.3
  • 3
    • 33847314656 scopus 로고    scopus 로고
    • Exploring the relationship between essential tremor and Parkinson's disease
    • Shahed J, Jankovic J. Exploring the relationship between essential tremor and Parkinson's disease. Parkinsonism Relat Disord 2007;13:67-76.
    • (2007) Parkinsonism Relat Disord , vol.13 , pp. 67-76
    • Shahed, J.1    Jankovic, J.2
  • 4
    • 77949535208 scopus 로고    scopus 로고
    • Revisiting the relationship between essential tremor and Parkinson's disease
    • Fekete R, Jankovic J. Revisiting the relationship between essential tremor and Parkinson's disease. Mov Disord 2010;25:503-4.
    • (2010) Mov Disord , vol.25 , pp. 503-504
    • Fekete, R.1    Jankovic, J.2
  • 5
    • 49849088686 scopus 로고    scopus 로고
    • Environmental epidemiology of essential tremor
    • Louis ED. Environmental epidemiology of essential tremor. Neuroepidemiology 2008;31:139-49.
    • (2008) Neuroepidemiology , vol.31 , pp. 139-149
    • Louis, E.D.1
  • 6
    • 77956857663 scopus 로고    scopus 로고
    • Differential effect of environmental risk factors on postural instability gait difficulties and tremor dominant Parkinson's disease
    • Skeie GO, Muller B, Haugarvoll K, Larsen JP, Tysnes OB. Differential effect of environmental risk factors on postural instability gait difficulties and tremor dominant Parkinson's disease. Mov Disord 2010;25:1847-52.
    • (2010) Mov Disord , vol.25 , pp. 1847-1852
    • Skeie, G.O.1    Muller, B.2    Haugarvoll, K.3    Larsen, J.P.4    Tysnes, O.B.5
  • 7
    • 34250815039 scopus 로고    scopus 로고
    • Genetics of essential tremor
    • Deng H, Le W, Jankovic J. Genetics of essential tremor. Brain 2007;130:1456-64.
    • (2007) Brain , vol.130 , pp. 1456-1464
    • Deng, H.1    Le, W.2    Jankovic, J.3
  • 8
    • 69949190043 scopus 로고    scopus 로고
    • Essential tremor in Parkinson's disease kindreds from a population of similar genetic background
    • Spanaki C, Plaitakis A. Essential tremor in Parkinson's disease kindreds from a population of similar genetic background. Mov Disord 2009;24:1662-8.
    • (2009) Mov Disord , vol.24 , pp. 1662-1668
    • Spanaki, C.1    Plaitakis, A.2
  • 9
    • 61349106502 scopus 로고    scopus 로고
    • Variant in the sequence of the LINGO1 gene confers risk of essential tremor
    • Stefansson H, Steinberg S, Petursson H et al. Variant in the sequence of the LINGO1 gene confers risk of essential tremor. Nat Genet 2009;41:277-9.
    • (2009) Nat Genet , vol.41 , pp. 277-279
    • Stefansson, H.1    Steinberg, S.2    Petursson, H.3
  • 10
    • 75749117533 scopus 로고    scopus 로고
    • LINGO1 rs9652490 is associated with essential tremor and Parkinson disease
    • Vilarino-Guell C, Ross OA, Wider C et al. LINGO1 rs9652490 is associated with essential tremor and Parkinson disease. Parkinsonism Relat Disord 2010;16:109-11.
    • (2010) Parkinsonism Relat Disord , vol.16 , pp. 109-111
    • Vilarino-Guell, C.1    Ross, O.A.2    Wider, C.3
  • 11
    • 70349755731 scopus 로고    scopus 로고
    • LINGO1 variant increases risk of familial essential tremor
    • Tan EK, Teo YY, Prakash KM et al. LINGO1 variant increases risk of familial essential tremor. Neurology 2009;73:1161-2.
    • (2009) Neurology , vol.73 , pp. 1161-1162
    • Tan, E.K.1    Teo, Y.Y.2    Prakash, K.M.3
  • 12
    • 77951860714 scopus 로고    scopus 로고
    • LINGO1 polymorphisms are associated with essential tremor in Europeans
    • Thier S, Lorenz D, Nothnagel M et al. LINGO1 polymorphisms are associated with essential tremor in Europeans. Mov Disord 2010;25:709-15.
    • (2010) Mov Disord , vol.25 , pp. 709-715
    • Thier, S.1    Lorenz, D.2    Nothnagel, M.3
  • 13
    • 78650039010 scopus 로고    scopus 로고
    • LINGO1 and LINGO2 variants are associated with essential tremor and Parkinson disease
    • Vilarino-Guell C, Wider C, Ross OA et al. LINGO1 and LINGO2 variants are associated with essential tremor and Parkinson disease. Neurogenetics 2010;11:401-8.
    • (2010) Neurogenetics , vol.11 , pp. 401-408
    • Vilarino-Guell, C.1    Wider, C.2    Ross, O.A.3
  • 14
    • 77953807518 scopus 로고    scopus 로고
    • Replication of the LINGO1 gene association with essential tremor in a North American population
    • Clark LN, Park N, Kisselev S, Rios E, Lee JH, Louis ED. Replication of the LINGO1 gene association with essential tremor in a North American population. Eur J Hum Genet 2010;18:838-43.
    • (2010) Eur J Hum Genet , vol.18 , pp. 838-843
    • Clark, L.N.1    Park, N.2    Kisselev, S.3    Rios, E.4    Lee, J.H.5    Louis, E.D.6
  • 15
    • 73949104319 scopus 로고    scopus 로고
    • Role of LINGO1 polymorphisms in Parkinson's Disease
    • Haubenberger D, Hotzy C, Pirker W et al. Role of LINGO1 polymorphisms in Parkinson's Disease. Mov Disord 2009;24:2404-7.
    • (2009) Mov Disord , vol.24 , pp. 2404-2407
    • Haubenberger, D.1    Hotzy, C.2    Pirker, W.3
  • 16
    • 76949101083 scopus 로고    scopus 로고
    • Analysis of LINGO1 (rs9652490) polymorphism in sporadic Parkinson's disease in a Polish population, and a meta-analysis
    • Bialecka M, Kurzawski M, Tan EK, Drozdzik M. Analysis of LINGO1 (rs9652490) polymorphism in sporadic Parkinson's disease in a Polish population, and a meta-analysis. Neurosci Lett 2010;472:53-5.
    • (2010) Neurosci Lett , vol.472 , pp. 53-55
    • Bialecka, M.1    Kurzawski, M.2    Tan, E.K.3    Drozdzik, M.4
  • 17
    • 77956105396 scopus 로고    scopus 로고
    • LINGO1 is not associated with Parkinson's disease in German patients
    • Klebe S, Thier S, Lorenz D et al. LINGO1 is not associated with Parkinson's disease in German patients. Am J Med Genet B Neuropsychiatr Genet 2010;153:1173-8.
    • (2010) Am J Med Genet B Neuropsychiatr Genet , vol.153 , pp. 1173-1178
    • Klebe, S.1    Thier, S.2    Lorenz, D.3
  • 18
    • 77955281246 scopus 로고    scopus 로고
    • Screening for two SNPs of LINGO1 gene in patients with essential tremor or sporadic Parkinson's disease in Chinese population
    • Zuo X, Jiang H, Guo JF et al. Screening for two SNPs of LINGO1 gene in patients with essential tremor or sporadic Parkinson's disease in Chinese population. Neurosci Lett 2010;481:69-72.
    • (2010) Neurosci Lett , vol.481 , pp. 69-72
    • Zuo, X.1    Jiang, H.2    Guo, J.F.3
  • 19
    • 78650205570 scopus 로고    scopus 로고
    • LINGO1 rs9652490 variant in Parkinson disease patients
    • Guo Y, Jankovic J, Song Z et al. LINGO1 rs9652490 variant in Parkinson disease patients. Neurosci Lett 2011;487:174-6.
    • (2011) Neurosci Lett , vol.487 , pp. 174-176
    • Guo, Y.1    Jankovic, J.2    Song, Z.3
  • 20
    • 79953671128 scopus 로고    scopus 로고
    • Genetic analysis of "leucine-rich repeat (LRR) and immunoglobulin (Ig) domain-containing, Nogo receptor-interacting protein-1 (LINGO1)" in two independent Chinese parkinson's disease populations
    • Wu YR, Tan EK, Chen CM, Kumar PM, Lee-Chen GJ, Chen ST. Genetic analysis of "leucine-rich repeat (LRR) and immunoglobulin (Ig) domain-containing, Nogo receptor-interacting protein-1 (LINGO1)" in two independent Chinese parkinson's disease populations. Am J Med Genet B Neuropsychiatr Genet 2011;156:99-103.
    • (2011) Am J Med Genet B Neuropsychiatr Genet , vol.156 , pp. 99-103
    • Wu, Y.R.1    Tan, E.K.2    Chen, C.M.3    Kumar, P.M.4    Lee-Chen, G.J.5    Chen, S.T.6
  • 21
    • 84155193049 scopus 로고    scopus 로고
    • Analysis of Lingo1 variant in sporadic and familial essential tremor among Asians
    • Wu YW, Rong TY, Li HH et al. Analysis of Lingo1 variant in sporadic and familial essential tremor among Asians. Acta Neurol Scand 2010. doi:
    • (2010) Acta Neurol Scand
    • Wu, Y.W.1    Rong, T.Y.2    Li, H.H.3
  • 23
    • 79960831310 scopus 로고    scopus 로고
    • Lack of association of LINGO1 rs9652490 and rs11856808 SNPs with familial essential tremor
    • Lorenzo-Betancor O, Garcia-Martin E, Cervantes S et al.Lack of association of LINGO1 rs9652490 and rs11856808 SNPs with familial essential tremor. Eur J Neurol 2010. doi:
    • (2010) Eur J Neurol
    • Lorenzo-Betancor, O.1    Garcia-Martin, E.2    Cervantes, S.3
  • 24
    • 79955502213 scopus 로고    scopus 로고
    • LINGO1 variants in the French-Canadian population
    • Bourassa CV, Riviere JB, Dion PA et al. LINGO1 variants in the French-Canadian population. PLoS ONE 2011;6:e16254.
    • (2011) PLoS ONE , vol.6
    • Bourassa, C.V.1    Riviere, J.B.2    Dion, P.A.3
  • 25
    • 16944361915 scopus 로고    scopus 로고
    • Mapping of a familial essential tremor gene, FET1, to chromosome 3q13
    • Gulcher JR, Jonsson P, Kong A et al. Mapping of a familial essential tremor gene, FET1, to chromosome 3q13. Nat Genet 1997;17:84-7.
    • (1997) Nat Genet , vol.17 , pp. 84-87
    • Gulcher, J.R.1    Jonsson, P.2    Kong, A.3
  • 26
    • 0030725721 scopus 로고    scopus 로고
    • A gene (ETM) for essential tremor maps to chromosome 2p22-p25
    • Higgins JJ, Pho LT, Nee LE. A gene (ETM) for essential tremor maps to chromosome 2p22-p25. Mov Disord 1997;12:859-64.
    • (1997) Mov Disord , vol.12 , pp. 859-864
    • Higgins, J.J.1    Pho, L.T.2    Nee, L.E.3
  • 27
    • 0031769723 scopus 로고    scopus 로고
    • Evidence that a gene for essential tremor maps to chromosome 2p in four families
    • Higgins JJ, Loveless JM, Jankovic J, Patel PI. Evidence that a gene for essential tremor maps to chromosome 2p in four families. Mov Disord 1998;13:972-7.
    • (1998) Mov Disord , vol.13 , pp. 972-977
    • Higgins, J.J.1    Loveless, J.M.2    Jankovic, J.3    Patel, P.I.4
  • 28
    • 33749244777 scopus 로고    scopus 로고
    • Genomewide scans in North American families reveal genetic linkage of essential tremor to a region on chromosome 6p23
    • Shatunov A, Sambuughin N, Jankovic J et al. Genomewide scans in North American families reveal genetic linkage of essential tremor to a region on chromosome 6p23. Brain 2006;129:2318-31.
    • (2006) Brain , vol.129 , pp. 2318-2331
    • Shatunov, A.1    Sambuughin, N.2    Jankovic, J.3
  • 29
    • 23844440598 scopus 로고    scopus 로고
    • Extended study of A265G variant of HS1BP3 in essential tremor and Parkinson disease
    • Deng H, Le WD, Guo Y, Huang MS, Xie WJ, Jankovic J. Extended study of A265G variant of HS1BP3 in essential tremor and Parkinson disease. Neurology 2005;65:651-2.
    • (2005) Neurology , vol.65 , pp. 651-652
    • Deng, H.1    Le, W.D.2    Guo, Y.3    Huang, M.S.4    Xie, W.J.5    Jankovic, J.6
  • 30
    • 33645730896 scopus 로고    scopus 로고
    • A variant in the HS1-BP3 gene is associated with familial essential tremor
    • Shatunov A, Jankovic J, Elble R et al. A variant in the HS1-BP3 gene is associated with familial essential tremor. Neurology 2005;65:1995.
    • (2005) Neurology , vol.65 , pp. 1995
    • Shatunov, A.1    Jankovic, J.2    Elble, R.3
  • 31
    • 33947192873 scopus 로고    scopus 로고
    • A family with Parkinson disease, essential tremor, bell palsy, and parkin mutations
    • Deng H, Le WD, Hunter CB, Mejia N, Xie WJ, Jankovic J. A family with Parkinson disease, essential tremor, bell palsy, and parkin mutations. Arch Neurol 2007;64:421-4.
    • (2007) Arch Neurol , vol.64 , pp. 421-424
    • Deng, H.1    Le, W.D.2    Hunter, C.B.3    Mejia, N.4    Xie, W.J.5    Jankovic, J.6
  • 32
    • 49549119640 scopus 로고    scopus 로고
    • Reappraisal of the role of the DRD3 gene in essential tremor
    • Blair MA, Ma S, Phibbs F et al. Reappraisal of the role of the DRD3 gene in essential tremor. Parkinsonism Relat Disord 2008;14:471-5.
    • (2008) Parkinsonism Relat Disord , vol.14 , pp. 471-475
    • Blair, M.A.1    Ma, S.2    Phibbs, F.3
  • 33
    • 67349241216 scopus 로고    scopus 로고
    • Dopamine receptor D3 gene and essential tremor in large series of German, Danish and French patients
    • Lorenz D, Klebe S, Stevanin G et al. Dopamine receptor D3 gene and essential tremor in large series of German, Danish and French patients. Eur J Hum Genet 2009;17:766-73.
    • (2009) Eur J Hum Genet , vol.17 , pp. 766-773
    • Lorenz, D.1    Klebe, S.2    Stevanin, G.3
  • 34
    • 3843066722 scopus 로고    scopus 로고
    • Unraveling the pathogenesis of Parkinson's disease - the contribution of monogenic forms
    • Bonifati V, Oostra BA, Heutink P. Unraveling the pathogenesis of Parkinson's disease - the contribution of monogenic forms. Cell Mol Life Sci 2004;61:1729-50.
    • (2004) Cell Mol Life Sci , vol.61 , pp. 1729-1750
    • Bonifati, V.1    Oostra, B.A.2    Heutink, P.3
  • 35
    • 70350759686 scopus 로고    scopus 로고
    • Pathogenesis of familial Parkinson's disease: new insights based on monogenic forms of Parkinson's disease
    • Hatano T, Kubo S, Sato S, Hattori N. Pathogenesis of familial Parkinson's disease: new insights based on monogenic forms of Parkinson's disease. J Neurochem 2009;111:1075-93.
    • (2009) J Neurochem , vol.111 , pp. 1075-1093
    • Hatano, T.1    Kubo, S.2    Sato, S.3    Hattori, N.4
  • 37
    • 0034647948 scopus 로고    scopus 로고
    • Mutation analysis and association studies of the UCHL1 gene in German Parkinson's disease patients
    • Wintermeyer P, Kruger R, Kuhn W et al. Mutation analysis and association studies of the UCHL1 gene in German Parkinson's disease patients. Neuroreport 2000;11:2079-82.
    • (2000) Neuroreport , vol.11 , pp. 2079-2082
    • Wintermeyer, P.1    Kruger, R.2    Kuhn, W.3
  • 39
    • 52649172690 scopus 로고    scopus 로고
    • Analysis of PARK genes in a Korean cohort of early-onset Parkinson disease
    • Choi JM, Woo MS, Ma HI et al. Analysis of PARK genes in a Korean cohort of early-onset Parkinson disease. Neurogenetics 2008;9:263-9.
    • (2008) Neurogenetics , vol.9 , pp. 263-269
    • Choi, J.M.1    Woo, M.S.2    Ma, H.I.3
  • 40
    • 63249092149 scopus 로고    scopus 로고
    • GIGYF2 Asn56Ser and Asn457Thr mutations in Parkinson disease patients
    • Guo Y, Jankovic J, Zhu S et al. GIGYF2 Asn56Ser and Asn457Thr mutations in Parkinson disease patients. Neurosci Lett 2009;454:209-11.
    • (2009) Neurosci Lett , vol.454 , pp. 209-211
    • Guo, Y.1    Jankovic, J.2    Zhu, S.3
  • 41
    • 74549196121 scopus 로고    scopus 로고
    • Analysis of the GIGYF2 gene in familial and sporadic Parkinson disease in the Spanish population
    • Samaranch L, Lorenzo E, Pastor MA et al. Analysis of the GIGYF2 gene in familial and sporadic Parkinson disease in the Spanish population. Eur J Neurol 2010;17:321-5.
    • (2010) Eur J Neurol , vol.17 , pp. 321-325
    • Samaranch, L.1    Lorenzo, E.2    Pastor, M.A.3
  • 42
    • 77954143799 scopus 로고    scopus 로고
    • Mutational screening and zebrafish functional analysis of GIGYF2 as a Parkinson-disease gene
    • Guella I, Pistocchi A, Asselta R et al. Mutational screening and zebrafish functional analysis of GIGYF2 as a Parkinson-disease gene. Neurobiol Aging 2010. doi:
    • (2010) Neurobiol Aging
    • Guella, I.1    Pistocchi, A.2    Asselta, R.3
  • 43
    • 0346788854 scopus 로고    scopus 로고
    • LRRN6A/LERN1 (leucine-rich repeat neuronal protein 1), a novel gene with enriched expression in limbic system and neocortex
    • Carim-Todd L, Escarceller M, Estivill X, Sumoy L. LRRN6A/LERN1 (leucine-rich repeat neuronal protein 1), a novel gene with enriched expression in limbic system and neocortex. Eur J Neurosci 2003;18:3167-82.
    • (2003) Eur J Neurosci , vol.18 , pp. 3167-3182
    • Carim-Todd, L.1    Escarceller, M.2    Estivill, X.3    Sumoy, L.4
  • 44
    • 33746883861 scopus 로고    scopus 로고
    • AMIGO and friends: an emerging family of brain-enriched, neuronal growth modulating, type I transmembrane proteins with leucine-rich repeats (LRR) and cell adhesion molecule motifs
    • Chen Y, Aulia S, Li L, Tang BL. AMIGO and friends: an emerging family of brain-enriched, neuronal growth modulating, type I transmembrane proteins with leucine-rich repeats (LRR) and cell adhesion molecule motifs. Brain Res Rev 2006;51:265-74.
    • (2006) Brain Res Rev , vol.51 , pp. 265-274
    • Chen, Y.1    Aulia, S.2    Li, L.3    Tang, B.L.4
  • 45
    • 33846009479 scopus 로고    scopus 로고
    • The structure of the Lingo-1 ectodomain, a module implicated in central nervous system repair inhibition
    • Mosyak L, Wood A, Dwyer B et al. The structure of the Lingo-1 ectodomain, a module implicated in central nervous system repair inhibition. J Biol Chem 2006;281:36378-90.
    • (2006) J Biol Chem , vol.281 , pp. 36378-36390
    • Mosyak, L.1    Wood, A.2    Dwyer, B.3
  • 46
    • 40149100815 scopus 로고    scopus 로고
    • Developmental analysis of Lingo-1/Lern1 protein expression in the mouse brain: interaction of its intracellular domain with Myt1l
    • Llorens F, Gil V, Iraola S et al. Developmental analysis of Lingo-1/Lern1 protein expression in the mouse brain: interaction of its intracellular domain with Myt1l. Dev Neurobiol 2008;68:521-41.
    • (2008) Dev Neurobiol , vol.68 , pp. 521-541
    • Llorens, F.1    Gil, V.2    Iraola, S.3
  • 47
    • 10744222190 scopus 로고    scopus 로고
    • LINGO-1 is a component of the Nogo-66 receptor/p75 signaling complex
    • Mi S, Lee X, Shao Z et al. LINGO-1 is a component of the Nogo-66 receptor/p75 signaling complex. Nat Neurosci 2004;7:221-8.
    • (2004) Nat Neurosci , vol.7 , pp. 221-228
    • Mi, S.1    Lee, X.2    Shao, Z.3
  • 48
    • 67650169896 scopus 로고    scopus 로고
    • LINGO-1 interacts with WNK1 to regulate nogo-induced inhibition of neurite extension
    • Zhang Z, Xu X, Zhang Y, Zhou J, Yu Z, He C. LINGO-1 interacts with WNK1 to regulate nogo-induced inhibition of neurite extension. J Biol Chem 2009;284:15717-28.
    • (2009) J Biol Chem , vol.284 , pp. 15717-15728
    • Zhang, Z.1    Xu, X.2    Zhang, Y.3    Zhou, J.4    Yu, Z.5    He, C.6
  • 49
    • 19944432743 scopus 로고    scopus 로고
    • TAJ/TROY, an orphan TNF receptor family member, binds Nogo-66 receptor 1 and regulates axonal regeneration
    • Shao Z, Browning JL, Lee X et al. TAJ/TROY, an orphan TNF receptor family member, binds Nogo-66 receptor 1 and regulates axonal regeneration. Neuron 2005;45:353-9.
    • (2005) Neuron , vol.45 , pp. 353-359
    • Shao, Z.1    Browning, J.L.2    Lee, X.3
  • 50
    • 0037038435 scopus 로고    scopus 로고
    • P75 interacts with the Nogo receptor as a co-receptor for Nogo, MAG and OMgp
    • Wang KC, Kim JA, Sivasankaran R, Segal R, He Z. P75 interacts with the Nogo receptor as a co-receptor for Nogo, MAG and OMgp. Nature 2002;420:74-8.
    • (2002) Nature , vol.420 , pp. 74-78
    • Wang, K.C.1    Kim, J.A.2    Sivasankaran, R.3    Segal, R.4    He, Z.5
  • 51
    • 0037408391 scopus 로고    scopus 로고
    • The p75 receptor acts as a displacement factor that releases Rho from Rho-GDI
    • Yamashita T, Tohyama M. The p75 receptor acts as a displacement factor that releases Rho from Rho-GDI. Nat Neurosci 2003;6:461-7.
    • (2003) Nat Neurosci , vol.6 , pp. 461-467
    • Yamashita, T.1    Tohyama, M.2
  • 52
    • 34948888764 scopus 로고    scopus 로고
    • LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis
    • Mi S, Hu B, Hahm K et al. LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis. Nat Med 2007;13:1228-33.
    • (2007) Nat Med , vol.13 , pp. 1228-1233
    • Mi, S.1    Hu, B.2    Hahm, K.3
  • 53
    • 33846128124 scopus 로고    scopus 로고
    • NGF regulates the expression of axonal LINGO-1 to inhibit oligodendrocyte differentiation and myelination
    • Lee X, Yang Z, Shao Z et al. NGF regulates the expression of axonal LINGO-1 to inhibit oligodendrocyte differentiation and myelination. J Neurosci 2007;27:220-5.
    • (2007) J Neurosci , vol.27 , pp. 220-225
    • Lee, X.1    Yang, Z.2    Shao, Z.3
  • 54
    • 46149107354 scopus 로고    scopus 로고
    • Inactivation of glycogen synthase kinase-3ß and up-regulation of LINGO-1 are involved in LINGO-1 antagonist regulated survival of cerebellar granular neurons
    • Zhao XH, Jin WL, Wu J, Mi S, Ju G. Inactivation of glycogen synthase kinase-3ß and up-regulation of LINGO-1 are involved in LINGO-1 antagonist regulated survival of cerebellar granular neurons. Cell Mol Neurobiol 2008;28:727-35.
    • (2008) Cell Mol Neurobiol , vol.28 , pp. 727-735
    • Zhao, X.H.1    Jin, W.L.2    Wu, J.3    Mi, S.4    Ju, G.5
  • 55
    • 22844453047 scopus 로고    scopus 로고
    • LINGO-1 negatively regulates myelination by oligodendrocytes
    • Mi S, Miller RH, Lee X et al. LINGO-1 negatively regulates myelination by oligodendrocytes. Nat Neurosci 2005;8:745-51.
    • (2005) Nat Neurosci , vol.8 , pp. 745-751
    • Mi, S.1    Miller, R.H.2    Lee, X.3
  • 56
    • 65249142739 scopus 로고    scopus 로고
    • Promotion of central nervous system remyelination by induced differentiation of oligodendrocyte precursor cells
    • Mi S, Miller RH, Tang W et al. Promotion of central nervous system remyelination by induced differentiation of oligodendrocyte precursor cells. Ann Neurol 2009;65:304-15.
    • (2009) Ann Neurol , vol.65 , pp. 304-315
    • Mi, S.1    Miller, R.H.2    Tang, W.3
  • 57
    • 35449003272 scopus 로고    scopus 로고
    • Inhibition of the leucine-rich repeat protein LINGO-1 enhances survival, structure, and function of dopaminergic neurons in Parkinson's disease models
    • Inoue H, Lin L, Lee X et al. Inhibition of the leucine-rich repeat protein LINGO-1 enhances survival, structure, and function of dopaminergic neurons in Parkinson's disease models. Proc Natl Acad Sci U S A 2007;104:14430-5.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 14430-14435
    • Inoue, H.1    Lin, L.2    Lee, X.3
  • 58
    • 33751256567 scopus 로고    scopus 로고
    • The familial Parkinsonism gene LRRK2 regulates neurite process morphology
    • Macleod D, Dowman J, Hammond R, Leete T, Inoue K, Abeliovich A. The familial Parkinsonism gene LRRK2 regulates neurite process morphology. Neuron 2006;52:587-93.
    • (2006) Neuron , vol.52 , pp. 587-593
    • Macleod, D.1    Dowman, J.2    Hammond, R.3    Leete, T.4    Inoue, K.5    Abeliovich, A.6
  • 59
    • 8844266996 scopus 로고    scopus 로고
    • Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease
    • Paisan-Ruiz C, Jain S, Evans EW et al. Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease. Neuron 2004;44:595-600.
    • (2004) Neuron , vol.44 , pp. 595-600
    • Paisan-Ruiz, C.1    Jain, S.2    Evans, E.W.3
  • 60
    • 8844233579 scopus 로고    scopus 로고
    • Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology
    • Zimprich A, Biskup S, Leitner P et al. Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology. Neuron 2004;44:601-7.
    • (2004) Neuron , vol.44 , pp. 601-607
    • Zimprich, A.1    Biskup, S.2    Leitner, P.3
  • 61
    • 59149101888 scopus 로고    scopus 로고
    • Etiopathogenesis of Parkinson's disease: a new beginning?
    • Le W, Chen S, Jankovic J. Etiopathogenesis of Parkinson's disease: a new beginning? Neuroscientist 2009;15:28-35.
    • (2009) Neuroscientist , vol.15 , pp. 28-35
    • Le, W.1    Chen, S.2    Jankovic, J.3
  • 63
    • 77953807213 scopus 로고    scopus 로고
    • LINGO1 and Essential Tremor: linking the shakes. Linking LINGO1 to essential tremor
    • Tan EK. LINGO1 and Essential Tremor: linking the shakes. Linking LINGO1 to essential tremor. Eur J Hum Genet 2010;18:739-40.
    • (2010) Eur J Hum Genet , vol.18 , pp. 739-740
    • Tan, E.K.1
  • 64
    • 33750629457 scopus 로고    scopus 로고
    • LINGO-1 antagonist promotes functional recovery and axonal sprouting after spinal cord injury
    • Ji B, Li M, Wu WT et al. LINGO-1 antagonist promotes functional recovery and axonal sprouting after spinal cord injury. Mol Cell Neurosci 2006;33:311-20.
    • (2006) Mol Cell Neurosci , vol.33 , pp. 311-320
    • Ji, B.1    Li, M.2    Wu, W.T.3
  • 65
    • 77950150049 scopus 로고    scopus 로고
    • Passive immunization with LINGO-1 polyclonal antiserum afforded neuroprotection and promoted functional recovery in a rat model of spinal cord injury
    • Lv J, Xu RX, Jiang XD et al. Passive immunization with LINGO-1 polyclonal antiserum afforded neuroprotection and promoted functional recovery in a rat model of spinal cord injury. Neuroimmunomodulation 2010;17:270-8.
    • (2010) Neuroimmunomodulation , vol.17 , pp. 270-278
    • Lv, J.1    Xu, R.X.2    Jiang, X.D.3
  • 66
    • 33846148013 scopus 로고    scopus 로고
    • TROY and LINGO-1 expression in astrocytes and macrophages/microglia in multiple sclerosis lesions
    • Satoh J, Tabunoki H, Yamamura T, Arima K, Konno H. TROY and LINGO-1 expression in astrocytes and macrophages/microglia in multiple sclerosis lesions. Neuropathol Appl Neurobiol 2007;33:99-107.
    • (2007) Neuropathol Appl Neurobiol , vol.33 , pp. 99-107
    • Satoh, J.1    Tabunoki, H.2    Yamamura, T.3    Arima, K.4    Konno, H.5
  • 67
    • 54349085579 scopus 로고    scopus 로고
    • LINGO-1 antagonists as therapy for multiple sclerosis: in vitro and in vivo evidence
    • Rudick RA, Mi S, Sandrock AW Jr. LINGO-1 antagonists as therapy for multiple sclerosis: in vitro and in vivo evidence. Expert Opin Biol Ther 2008;8:1561-70.
    • (2008) Expert Opin Biol Ther , vol.8 , pp. 1561-1570
    • Rudick, R.A.1    Mi, S.2    Sandrock Jr., A.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.