Analysis of the GIGYF2 gene in familial and sporadic Parkinson disease in the Spanish population

European Journal of Neurology

Volumn 17, Issue 2, 2010, Pages 321-325

  Samaranch, L ^a   Lorenzo, E ^a   Pastor, M A ^b   Riverol, M ^b   Luquin, M R ^b   Rodriguez Oroz M C ^b   Obeso, J A ^b   Pastor, P ^a,b  

^a UNIVERSITY OF NAVARRA   (Spain)

^b UNIVERSITY CLINIC OF NAVARRA   (Spain)

Author keywords

Genetics; PARK11

Indexed keywords

GLUTAMINE; PARKIN; PROLINE; TNRC15 PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; EXON; FAMILIAL DISEASE; GENE SEGREGATION; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HUMAN; MAJOR CLINICAL STUDY; MISSENSE MUTATION; NUCLEOTIDE SEQUENCE; PARKINSON DISEASE; PRIORITY JOURNAL; PROMOTER REGION;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CARRIER PROTEINS; CHROMOSOMES, HUMAN, PAIR 2; EUROPEAN CONTINENTAL ANCESTRY GROUP; EXONS; FAMILY; FEMALE; GENETIC ASSOCIATION STUDIES; GENETIC VARIATION; HUMANS; MIDDLE AGED; MUTATION; PARKINSON DISEASE; POLYMORPHISM, SINGLE NUCLEOTIDE; SEQUENCE ANALYSIS, DNA; SPAIN; UBIQUITIN-PROTEIN LIGASES; YOUNG ADULT;

EID: 74549196121     PISSN: 13515101     EISSN: 14681331     Source Type: Journal    
DOI: 10.1111/j.1468-1331.2009.02812.x     Document Type: Article

References (15)

1. de Rijk MC, Launer LJ, Berger K, et al. Prevalence of Parkinson's disease in Europe: a collaborative study of population-based cohorts. Neurologic Diseases in the Elderly Research Group. Neurology 2000 54 : S21 S23.
2. Vila M, Przedborski S. Genetic clues to the pathogenesis of Parkinson's disease. Nat Med 2004 10 (Suppl. S58 S62.
3. Pankratz N, Nichols WC, Uniacke SK, et al. Genome-wide linkage analysis and evidence of gene-by-gene interactions in a sample of 362 multiplex Parkinson disease families. Hum Mol Genet 2003 12 : 2599 2608.
4. Pankratz N, Nichols WC, Uniacke SK, et al. Genome screen to identify susceptibility genes for Parkinson disease in a sample without parkin mutations. Am J Hum Genet 2002 71 : 124 135.
5. Pankratz N, Nichols WC, Uniacke SK, et al. Significant linkage of Parkinson disease to chromosome 2q36-37. Am J Hum Genet 2003 72 : 1053 1057.
6. Giovannone B, Lee E, Laviola L, Giorgino F, Cleveland KA, Smith RJ. Two novel proteins that are linked to insulin-like growth factor (IGF-I) receptors by the Grb10 adapter and modulate IGF-I signaling. J Biol Chem 2003 278 : 31564 31573.
7. Lautier C, Goldwurm S, Durr A, et al. Mutations in the GIGYF2 (TNRC15) gene at the PARK11 locus in familial Parkinson disease. Am J Hum Genet 2008 82 : 822 833.
8. Nichols WC, Kissell DK, Pankratz N, et al. Variation in GIGYF2 is not associated with Parkinson disease. Neurology 2009 72 : 1886 1892.
9. Sutherland GT, Siebert GA, Newman JR, et al. Haplotype analysis of the PARK 11 gene, GIGYF2, in sporadic Parkinson's disease. Mov Disord 2009 24 : 449 452.
10. Vilarino-Guell C, Ross OA, Soto AI, et al. Reported mutations in GIGYF2 are not a common cause of Parkinson's disease. Mov Disord 2009 24 : 619 620.
11. Zimprich A, Schulte C, Reinthaler E, et al. PARK11 gene (GIGYF2) variants Asn56Ser and Asn457Thr are not pathogenic for Parkinson's disease. Parkinsonism Relat Disord 2009 15 : 532 534.
12. Bras J, Simon-Sanchez J, Federoff M, et al. Lack of replication of association between GIGYF2 variants and Parkinson disease. Hum Mol Genet 2009 18 : 341 346.
13. Gelb DJ, Oliver E, Gilman S. Diagnostic criteria for Parkinson disease. Arch Neurol 1999 56 : 33 39.
14. Marder K, Levy G, Louis ED, et al. Accuracy of family history data on Parkinson's disease. Neurology 2003 61 : 18 23.
15. Kachergus J, Mata IF, Hulihan M, et al. Identification of a novel LRRK2 mutation linked to autosomal dominant parkinsonism: evidence of a common founder across European populations. Am J Hum Genet 2005 76 : 672 680.