Pharmacological activation of small conductance calcium- activated potassium channels with naphtho[1,2-d]thiazol-2-ylamine decreases guinea pig detrusor smooth muscle excitability and contractility

Journal of Pharmacology and Experimental Therapeutics

Volumn 340, Issue 1, 2012, Pages 114-123

  Parajuli, Shankar P ^a   Soder, Rupal P ^a   Hristov, Kiril L ^a   Petkov, Georgi V ^a  

^a UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERMEDIATE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; MESSENGER RNA; NAPHTHO[1,2 D]THIAZOL 2 YLAMINE; POTASSIUM CHANNEL STIMULATING AGENT; SKA 31; SMALL CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; SMALL CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL 1; SMALL CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL 2; SMALL CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL 3; UNCLASSIFIED DRUG;

AMPLITUDE MODULATION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DETRUSOR MUSCLE; DRUG EFFECT; FREQUENCY MODULATION; GUINEA PIG; HYPERPOLARIZATION; MALE; MUSCLE EXCITATION; MUSCLE FIBER MEMBRANE STEADY POTENTIAL; MUSCLE FORCE; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMOOTH MUSCLE CONTRACTILITY; SMOOTH MUSCLE CONTRACTION; SMOOTH MUSCLE FIBER;

ANIMALS; BENZOTHIAZOLES; BLOTTING, WESTERN; CALCIUM CHANNEL AGONISTS; CELL SEPARATION; DATA INTERPRETATION, STATISTICAL; GUINEA PIGS; ISOMETRIC CONTRACTION; MALE; MEMBRANE POTENTIALS; MUSCLE CONTRACTION; MUSCLE, SMOOTH; MYOCYTES, SMOOTH MUSCLE; PATCH-CLAMP TECHNIQUES; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; URINARY BLADDER;

EID: 84055223419     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.111.186213     Document Type: Article

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