Effect of the SK/IK channel modulator 4,5-dichloro-1,3-diethyl-1,3-dihydro- benzoimidazol-2-one (NS4591) on contractile force in rat, pig and human detrusor smooth muscle

BJU International

Volumn 108, Issue 5, 2011, Pages 771-777

  Nielsen, Jens Steen ^a   Rode, Frederik ^b   Rahbek, Mette ^a   Andersson, Karl Erik ^c   Rønn, Lars Christian ^b   Bouchelouche, Kirsten ^a   Nordling, Jorgen ^a   Bouchelouche, Pierre ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b NEUROSEARCH A S   (Denmark)

^c WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

detrusor; NS4591; OAB; SK channels

Indexed keywords

4,5 DICHLORO 1,3 DIETHYL 1,3 DIHYDROBENZOIMIDAZOL 2 ONE; APAMIN; CARBACHOL; FURA 2; IBERIOTOXIN; INTERMEDIATE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; NS 4591; POTASSIUM CHANNEL BLOCKING AGENT; SMALL CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; UNCLASSIFIED DRUG;

ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLADDER CANCER; CALCIUM CELL LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; CYSTECTOMY; DETRUSOR MUSCLE; DRUG EFFICACY; ELECTROSTIMULATION; FEMALE; HUMAN; HUMAN CELL; MALE; MICROFLUOROMETRY; MUSCLE BIOPSY; MYOGRAPHY; NONHUMAN; OSCILLATION; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE CONTRACTILITY; SMOOTH MUSCLE CONTRACTION; SMOOTH MUSCLE FIBER; SWINE;

AGED; ANIMALS; BENZIMIDAZOLES; CYSTECTOMY; ELECTRIC STIMULATION; FEMALE; HUMANS; MALE; MIDDLE AGED; MUSCLE CONTRACTION; MUSCLE, SMOOTH; POTASSIUM CHANNEL BLOCKERS; RATS; RATS, SPRAGUE-DAWLEY; SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; SWINE; URINARY BLADDER; URINARY BLADDER NEOPLASMS;

EID: 80052000253     PISSN: 14644096     EISSN: 1464410X     Source Type: Journal    
DOI: 10.1111/j.1464-410X.2010.10019.x     Document Type: Article

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