메뉴 건너뛰기




Volumn 20, Issue 4, 2011, Pages 397-406

Hepatitis C virus infection and genetic susceptibility to therapy

Author keywords

Genetic variants; Hcv; IL28B; Interferon; Therapy

Indexed keywords

ANTIVIRUS AGENT; BOCEPREVIR; INTERLEUKIN 28B; PROTEINASE INHIBITOR; TELAPREVIR;

EID: 84055212289     PISSN: 18418724     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (7)

References (116)
  • 1
    • 33644875265 scopus 로고    scopus 로고
    • Spontaneous viral clearance following acute hepatitis C infection: A systematic review of longitudinal studies
    • Micallef JM, Kaldor JM, Dore GJ. Spontaneous viral clearance following acute hepatitis C infection: a systematic review of longitudinal studies. J Viral Hepat 2006; 13: 34-41.
    • (2006) J Viral Hepat , vol.13 , pp. 34-41
    • Micallef, J.M.1    Kaldor, J.M.2    Dore, G.J.3
  • 2
    • 59149085501 scopus 로고    scopus 로고
    • The global burden of hepatitis C
    • Lavanchy D. The global burden of hepatitis C. Liver Int 2009; 29 Suppl 1: 74-81.
    • Liver Int 2009 , vol.29 , Issue.SUPPL. 1 , pp. 74-81
    • Lavanchy, D.1
  • 3
    • 0035934568 scopus 로고    scopus 로고
    • Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: A randomised trial
    • Manns MP, McHutchison JG, Gordon SC, et al. Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial. Lancet 2001; 358: 958-965.
    • (2001) Lancet , vol.358 , pp. 958-965
    • Manns, M.P.1    McHutchison, J.G.2    Gordon, S.C.3
  • 4
    • 0037179698 scopus 로고    scopus 로고
    • Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection
    • Fried MW, Shiffman ML, Reddy KR, et al. Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection. N Engl J Med 2002; 347: 975-982.
    • (2002) N Engl J Med , vol.347 , pp. 975-982
    • Fried, M.W.1    Shiffman, M.L.2    Reddy, K.R.3
  • 5
    • 0037133079 scopus 로고    scopus 로고
    • Surprisingly small effect of antiviral treatment in patients with hepatitis C
    • Falck-Ytter Y, Kale H, Mullen KD, et al. Surprisingly small effect of antiviral treatment in patients with hepatitis C. Ann Intern Med 2002; 136: 288-292.
    • (2002) Ann Intern Med , vol.136 , pp. 288-292
    • Falck-Ytter, Y.1    Kale, H.2    Mullen, K.D.3
  • 6
    • 59149097207 scopus 로고    scopus 로고
    • Expert opinion on the treatment of patients with chronic hepatitis C
    • Zeuzem S, Berg T, Moeller B, et al. Expert opinion on the treatment of patients with chronic hepatitis C. J Viral Hepat 2009; 16: 75-90.
    • (2009) J Viral Hepat , vol.16 , pp. 75-90
    • Zeuzem, S.1    Berg, T.2    Moeller, B.3
  • 7
    • 33847054368 scopus 로고    scopus 로고
    • Genetics, genomics, and proteomics: Implications for the diagnosis and the treatment of chronic hepatitis C
    • Asselah T, Bièche I, Paradis V, Bedossa P, Vidaud M, Marcellin P. Genetics, genomics, and proteomics: implications for the diagnosis and the treatment of chronic hepatitis C. Semin Liver Dis 2007; 27: 13-27.
    • (2007) Semin Liver Dis , vol.27 , pp. 13-27
    • Asselah, T.1    Bièche, I.2    Paradis, V.3    Bedossa, P.4    Vidaud, M.5    Marcellin, P.6
  • 8
    • 65949107547 scopus 로고    scopus 로고
    • Common genetic variation and human traits
    • Goldstein DB. Common genetic variation and human traits. N Engl J Med 2009; 360: 1696-1698.
    • (2009) N Engl J Med , vol.360 , pp. 1696-1698
    • Goldstein, D.B.1
  • 9
    • 34249997024 scopus 로고    scopus 로고
    • Replicating genotype-phenotype associations
    • NCI-NHGRI Working Group on Replication in Association Studies, Chanock SJ, Manolio T, et al
    • NCI-NHGRI Working Group on Replication in Association Studies, Chanock SJ, Manolio T, et al. Replicating genotype-phenotype associations. Nature 2007; 447: 655-660.
    • (2007) Nature , vol.447 , pp. 655-660
  • 10
    • 17244378016 scopus 로고    scopus 로고
    • Genetics. Was the Human Genome Project worth the effort
    • Daiger SP. Genetics. Was the Human Genome Project worth the effort? Science 2005; 308: 362-364.
    • (2005) Science , vol.308 , pp. 362-364
    • Daiger, S.P.1
  • 11
    • 33947285368 scopus 로고    scopus 로고
    • What genome-wide association studies can do for medicine
    • Christensen K, Murray JC. What genome-wide association studies can do for medicine. N Engl J Med 2007; 356: 1094-1097.
    • (2007) N Engl J Med , vol.356 , pp. 1094-1097
    • Christensen, K.1    Murray, J.C.2
  • 12
    • 70349966196 scopus 로고    scopus 로고
    • Genetic variation in IL28B and spontaneous clearance of hepatitis C virus
    • Thomas DL, Thio CL, Martin MP, et al. Genetic variation in IL28B and spontaneous clearance of hepatitis C virus. Nature 2009; 461: 798-801.
    • (2009) Nature , vol.461 , pp. 798-801
    • Thomas, D.L.1    Thio, C.L.2    Martin, M.P.3
  • 13
    • 70349292099 scopus 로고    scopus 로고
    • Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance
    • Ge D, Fellay J, Thompson AJ, et al. Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance. Nature 2009; 461: 399-401.
    • (2009) Nature , vol.461 , pp. 399-401
    • Ge, D.1    Fellay, J.2    Thompson, A.J.3
  • 14
    • 70349548852 scopus 로고    scopus 로고
    • IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy
    • Suppiah V, Moldovan M, Ahlenstiel G, et al. IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy. Nat Genet 2009; 41: 1100-1104.
    • (2009) Nat Genet , vol.41 , pp. 1100-1104
    • Suppiah, V.1    Moldovan, M.2    Ahlenstiel, G.3
  • 15
    • 70349533037 scopus 로고    scopus 로고
    • Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C
    • Tanaka Y, Nishida N, Sugiyama M, et al. Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C. Nat Genet 2009; 41: 1105-1109.
    • (2009) Nat Genet , vol.41 , pp. 1105-1109
    • Tanaka, Y.1    Nishida, N.2    Sugiyama, M.3
  • 16
    • 77949831342 scopus 로고    scopus 로고
    • Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: A genomewide association study
    • 1345
    • Rauch A, Kutalik Z, Descombes P, et al. Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genomewide association study. Gastroenterology 2010; 138: 1338-1345, 1345 e1-7.
    • (2010) Gastroenterology , vol.138 , Issue.1338-1345
    • Rauch, A.1    Kutalik, Z.2    Descombes, P.3
  • 17
    • 65549143648 scopus 로고    scopus 로고
    • Type III IFNs: New layers of complexity in innate antiviral immunity
    • Ank N, Paludan SR. Type III IFNs: new layers of complexity in innate antiviral immunity. Biofactors 2009; 35: 82-87.
    • (2009) Biofactors , vol.35 , pp. 82-87
    • Ank, N.1    Paludan, S.R.2
  • 18
    • 31344461659 scopus 로고    scopus 로고
    • Innate immune recognition of viral infection
    • Kawai T, Akira S. Innate immune recognition of viral infection. Nat Immunol 2006; 7: 131-137.
    • (2006) Nat Immunol , vol.7 , pp. 131-137
    • Kawai, T.1    Akira, S.2
  • 19
    • 33845605155 scopus 로고    scopus 로고
    • Interferons alpha and lambda inhibit hepatitis C virus replication with distinct signal transduction and gene regulation kinetics
    • Marcello T, Grakoui A, Barba-Spaeth G, et al. Interferons alpha and lambda inhibit hepatitis C virus replication with distinct signal transduction and gene regulation kinetics. Gastroenterology 2006; 131: 1887-1898.
    • (2006) Gastroenterology , vol.131 , pp. 1887-1898
    • Marcello, T.1    Grakoui, A.2    Barba-Spaeth, G.3
  • 20
    • 68849124573 scopus 로고    scopus 로고
    • Interferon-lambdas: The modulators of antivirus, antitumor, and immune responses
    • Li M, Liu X, Zhou Y, Su SB. Interferon-lambdas: the modulators of antivirus, antitumor, and immune responses. J Leukoc Biol 2009; 86: 23-32.
    • (2009) J Leukoc Biol , vol.86 , pp. 23-32
    • Li, M.1    Liu, X.2    Zhou, Y.3    Su, S.B.4
  • 21
    • 80052161834 scopus 로고    scopus 로고
    • Do lambda-IFNs IL28A and IL28B act on human natural killer cells?
    • Krämer B, Eisenhardt M, Glässner A, et al. Do lambda-IFNs IL28A and IL28B act on human natural killer cells? Proc Natl Acad Sci U S A 2011; 108: E519-520.
    • (2011) Proc Natl Acad Sci U S A , vol.108
    • Krämer, B.1    Eisenhardt, M.2    Glässner, A.3
  • 22
    • 79956147625 scopus 로고    scopus 로고
    • IL28 variation affects expression of interferon stimulated genes and peg-interferon and ribavirin therapy
    • Abe H, Hayes CN, Ochi H, et al. IL28 variation affects expression of interferon stimulated genes and peg-interferon and ribavirin therapy. J Hepatol 2011; 54: 1094-1101.
    • (2011) J Hepatol , vol.54 , pp. 1094-1101
    • Abe, H.1    Hayes, C.N.2    Ochi, H.3
  • 23
    • 84055198779 scopus 로고    scopus 로고
    • Genotype rs8099917 near the IL28B gene and amino acid substitution at position 70 in the core region of the hepatitis C virus are determinants of serum apolipoprotein B-100 concentration in chronic hepatitis C
    • Aug 31. [Epub ahead of print]
    • Aizawa Y, Yohizawa K, Aida Y, Ishiguro H, Abe H, Tsubota A. Genotype rs8099917 near the IL28B gene and amino acid substitution at position 70 in the core region of the hepatitis C virus are determinants of serum apolipoprotein B-100 concentration in chronic hepatitis C. Mol Cell Biochem 2011 Aug 31. [Epub ahead of print]
    • (2011) Mol Cell Biochem
    • Aizawa, Y.1    Yohizawa, K.2    Aida, Y.3    Ishiguro, H.4    Abe, H.5    Tsubota, A.6
  • 24
    • 78149427491 scopus 로고    scopus 로고
    • IL28B SNP rs8099917 is strongly associated with pegylated interferon-alpha and ribavirin therapy treatment failure in HCV/HIV-1 coinfected patients
    • Aparicio E, Parera M, Franco S, et al. IL28B SNP rs8099917 is strongly associated with pegylated interferon-alpha and ribavirin therapy treatment failure in HCV/HIV-1 coinfected patients. PLoS One 2010; 5: e13771.
    • (2010) PLoS One , vol.5
    • Aparicio, E.1    Parera, M.2    Franco, S.3
  • 25
    • 79960382329 scopus 로고    scopus 로고
    • IL28B polymorphisms predict reduction of HCV RNA from the first day of therapy in chronic hepatitis C
    • Bochud PY, Bibert S, Negro F, et al. IL28B polymorphisms predict reduction of HCV RNA from the first day of therapy in chronic hepatitis C. J Hepatol 2011; 55: 980-988.
    • (2011) J Hepatol , vol.55 , pp. 980-988
    • Bochud, P.Y.1    Bibert, S.2    Negro, F.3
  • 26
    • 79957982710 scopus 로고    scopus 로고
    • IL28B genetic variations are associated with high sustained virological response (SVR) of interferon-alpha plus ribavirin therapy in Taiwanese chronic HCV infection
    • Chen JY, Lin CY, Wang CM, et al. IL28B genetic variations are associated with high sustained virological response (SVR) of interferon-alpha plus ribavirin therapy in Taiwanese chronic HCV infection. Genes Immun 2011; 12: 300-309.
    • (2011) Genes Immun , vol.12 , pp. 300-309
    • Chen, J.Y.1    Lin, C.Y.2    Wang, C.M.3
  • 27
    • 78650971350 scopus 로고    scopus 로고
    • Screening for IL28B gene variants identifies predictors of hepatitis C therapy success
    • Doehring A, Hofmann WP, Schlecker C, et al., Screening for IL28B gene variants identifies predictors of hepatitis C therapy success. Antivir Ther 2010; 15:1099-1106.
    • (2010) Antivir Ther , vol.15 , pp. 1099-1106
    • Doehring, A.1    Hofmann, W.P.2    Schlecker, C.3
  • 28
    • 78651107054 scopus 로고    scopus 로고
    • HCV substitutions and IL28B polymorphisms on outcome of peg-interferon plus ribavirin combination therapy
    • Hayes CN, Kobayashi M, Akuta N, et al. HCV substitutions and IL28B polymorphisms on outcome of peg-interferon plus ribavirin combination therapy. Gut 2011; 60: 261-267.
    • (2011) Gut , vol.60 , pp. 261-267
    • Hayes, C.N.1    Kobayashi, M.2    Akuta, N.3
  • 29
    • 79955542560 scopus 로고    scopus 로고
    • The rs8099917 polymorphism, when determined by a suitable genotyping method, is a better predictor for response to pegylated alpha interferon/ribavirin therapy in Japanese patients than other single nucleotide polymorphisms associated with interleukin-28B
    • Ito K, Higami K, Masaki N, et al. The rs8099917 polymorphism, when determined by a suitable genotyping method, is a better predictor for response to pegylated alpha interferon/ribavirin therapy in Japanese patients than other single nucleotide polymorphisms associated with interleukin-28B. J Clin Microbiol 2011; 49: 1853-1860.
    • (2011) J Clin Microbiol , vol.49 , pp. 1853-1860
    • Ito, K.1    Higami, K.2    Masaki, N.3
  • 30
    • 78851469540 scopus 로고    scopus 로고
    • Pre-treatment prediction of response to pegylated-interferon plus ribavirin for chronic hepatitis C using genetic polymorphism in IL28B and viral factors
    • Kurosaki M, Tanaka Y, Nishida N, et al. Pre-treatment prediction of response to pegylated-interferon plus ribavirin for chronic hepatitis C using genetic polymorphism in IL28B and viral factors. J Hepatol 2011; 54: 439-448.
    • (2011) J Hepatol , vol.54 , pp. 439-448
    • Kurosaki, M.1    Tanaka, Y.2    Nishida, N.3
  • 31
    • 79953183019 scopus 로고    scopus 로고
    • Association of genetic variation in IL28B with hepatitis C treatment-induced viral clearance in the Chinese Han population
    • Liao XW, Ling Y, Li XH, et al. Association of genetic variation in IL28B with hepatitis C treatment-induced viral clearance in the Chinese Han population. Antivir Ther 2011; 16: 141-147.
    • (2011) Antivir Ther , vol.16 , pp. 141-147
    • Liao, X.W.1    Ling, Y.2    Li, X.H.3
  • 32
    • 79953298817 scopus 로고    scopus 로고
    • IL28B SNP rs12979860 is a critical predictor for on-treatment and sustained virologic response in patients with hepatitis C virus genotype-1 infection
    • Lin CY, Chen JY, Lin TN, et al., IL28B SNP rs12979860 is a critical predictor for on-treatment and sustained virologic response in patients with hepatitis C virus genotype-1 infection. PLoS One 2011; 6: p. e18322.
    • (2011) PLoS One , vol.6
    • Lin, C.Y.1    Chen, J.Y.2    Lin, T.N.3
  • 33
    • 79959587024 scopus 로고    scopus 로고
    • IL28B polymorphisms determine early viral kinetics and treatment outcome in patients receiving peginterferon/ribavirin for chronic hepatitis C genotype 1
    • Lindh M, Lagging M, Arnholm B, et al. IL28B polymorphisms determine early viral kinetics and treatment outcome in patients receiving peginterferon/ribavirin for chronic hepatitis C genotype 1. J Viral Hepat 2011; 18: e325-331.
    • (2011) J Viral Hepat , vol.18
    • Lindh, M.1    Lagging, M.2    Arnholm, B.3
  • 34
    • 79960028292 scopus 로고    scopus 로고
    • IL28B Polymorphism Is Associated with Both Side Effects and Clearance of Hepatitis C During Interferon-Alpha Therapy
    • Dec 6. [Epub ahead of print]
    • Lotrich FE, Loftis JM, Ferrell RE, Rabinovitz M, Hauser P. IL28B Polymorphism Is Associated with Both Side Effects and Clearance of Hepatitis C During Interferon-Alpha Therapy. J Interferon Cytokine Res 2010 Dec 6. [Epub ahead of print]
    • (2010) J Interferon Cytokine Res
    • Lotrich, F.E.1    Loftis, J.M.2    Ferrell, R.E.3    Rabinovitz, M.4    Hauser, P.5
  • 35
    • 84925580987 scopus 로고    scopus 로고
    • An IL28B polymorphism determines treatment response of hepatitis C virus genotype 2 or 3 patients who do not achieve a rapid virologic response
    • 827.e1
    • Mangia A, Thompson AJ, Santoro R, et al. An IL28B polymorphism determines treatment response of hepatitis C virus genotype 2 or 3 patients who do not achieve a rapid virologic response. Gastroenterology 2010; 139: 821-827, 827.e1.
    • (2010) Gastroenterology , vol.139 , pp. 821-827
    • Mangia, A.1    Thompson, A.J.2    Santoro, R.3
  • 36
    • 77952693487 scopus 로고    scopus 로고
    • Replicated association between an IL28B gene variant and a sustained response to pegylated interferon and ribavirin
    • McCarthy JJ, Li JH, Thompson A, et al., Replicated association between an IL28B gene variant and a sustained response to pegylated interferon and ribavirin. Gastroenterology 2010; 138: 2307-2314.
    • (2010) Gastroenterology , vol.138 , pp. 2307-2314
    • McCarthy, J.J.1    Li, J.H.2    Thompson, A.3
  • 37
    • 79955591125 scopus 로고    scopus 로고
    • IL-28B predicts response to chronic hepatitis C therapy--fine-mapping and replication study in Asian populations
    • Ochi H, Maekawa T, Abe H, et al. IL-28B predicts response to chronic hepatitis C therapy--fine-mapping and replication study in Asian populations. J Gen Virol 2011; 92: 1071-1081.
    • (2011) J Gen Virol , vol.92 , pp. 1071-1081
    • Ochi, H.1    Maekawa, T.2    Abe, H.3
  • 38
    • 79952712673 scopus 로고    scopus 로고
    • Association of IL28B variants with response to pegylated-interferon alpha plus ribavirin combination therapy reveals intersubgenotypic differences between genotypes 2a and 2b
    • Sakamoto N, Nakagawa M, Tanaka Y, et al. Association of IL28B variants with response to pegylated-interferon alpha plus ribavirin combination therapy reveals intersubgenotypic differences between genotypes 2a and 2b. J Med Virol 2011; 83: 871-878.
    • (2011) J Med Virol , vol.83 , pp. 871-878
    • Sakamoto, N.1    Nakagawa, M.2    Tanaka, Y.3
  • 39
    • 80052360000 scopus 로고    scopus 로고
    • Association of a single nucleotide polymorphism near the interleukin-28B gene with response to hepatitis C therapy in Asian patients
    • Sinn DH, Kim YJ, Lee ST, et al., Association of a single nucleotide polymorphism near the interleukin-28B gene with response to hepatitis C therapy in Asian patients. J Gastroenterol Hepatol 2011; 26: 1374-1379.
    • (2011) J Gastroenterol Hepatol , vol.26 , pp. 1374-1379
    • Sinn, D.H.1    Kim, Y.J.2    Lee, S.T.3
  • 40
    • 80052153278 scopus 로고    scopus 로고
    • Identification of improved IL28B SNPs and haplotypes for prediction of drug response in treatment of hepatitis C using massively parallel sequencing in a cross-sectional European cohort
    • Smith KR, Suppiah V, O'Connor K, et al. Identification of improved IL28B SNPs and haplotypes for prediction of drug response in treatment of hepatitis C using massively parallel sequencing in a cross-sectional European cohort. Genome Med 2011; 3: 57.
    • (2011) Genome Med , vol.3 , pp. 57
    • Smith, K.R.1    Suppiah, V.2    O'Connor, K.3
  • 41
    • 77953881002 scopus 로고    scopus 로고
    • Interleukin-28B polymorphism improves viral kinetics and is the strongest pretreatment predictor of sustained virologic response in genotype 1 hepatitis C virus
    • Thompson AJ, Muir AJ, Sulkowski MS, et al. Interleukin-28B polymorphism improves viral kinetics and is the strongest pretreatment predictor of sustained virologic response in genotype 1 hepatitis C virus. Gastroenterology 2010; 139: 120-129.e18.
    • (2010) Gastroenterology , vol.139 , Issue.120-129
    • Thompson, A.J.1    Muir, A.J.2    Sulkowski, M.S.3
  • 42
    • 79955894224 scopus 로고    scopus 로고
    • Impact of genetic polymorphisms near the IL28B gene and amino acid substitutions in the hepatitis C virus core region on interferon sensitivity/resistance in patients with chronic hepatitis C
    • Toyoda H, Kumada T, Tada T, Kawaguchi T, Murakami Y, Matsuda F. Impact of genetic polymorphisms near the IL28B gene and amino acid substitutions in the hepatitis C virus core region on interferon sensitivity/resistance in patients with chronic hepatitis C. J Med Virol 2011; 83: 1203-1211.
    • (2011) J Med Virol , vol.83 , pp. 1203-1211
    • Toyoda, H.1    Kumada, T.2    Tada, T.3    Kawaguchi, T.4    Murakami, Y.5    Matsuda, F.6
  • 43
    • 78649320722 scopus 로고    scopus 로고
    • Role of interleukin-28B polymorphisms in the treatment of hepatitis C virus genotype 2 infection in Asian patients
    • Yu ML, Huang CF, Huang JF, et al. Role of interleukin-28B polymorphisms in the treatment of hepatitis C virus genotype 2 infection in Asian patients. Hepatology 2011; 53: 7-13.
    • (2011) Hepatology , vol.53 , pp. 7-13
    • Yu, M.L.1    Huang, C.F.2    Huang, J.F.3
  • 44
    • 80055047790 scopus 로고    scopus 로고
    • Impact of IL28B on treatment outcome in hepatitis C virus G1/4 patients receiving response-guided therapy with peginterferon alpha-2a (40KD)/ ribavirin
    • Scherzer TM, Stättermayer AF, Strasser M, et al. Impact of IL28B on treatment outcome in hepatitis C virus G1/4 patients receiving response-guided therapy with peginterferon alpha-2a (40KD)/ ribavirin. Hepatology 2011; 54: 1518-1526.
    • (2011) Hepatology , vol.54 , pp. 1518-1526
    • Scherzer, T.M.1    Stättermayer, A.F.2    Strasser, M.3
  • 45
    • 79951679619 scopus 로고    scopus 로고
    • Importance of IL28B gene polymorphisms in hepatitis C virus genotype 2 and 3 infected patients
    • Sarrazin C, Susser S, Doehring A, et al. Importance of IL28B gene polymorphisms in hepatitis C virus genotype 2 and 3 infected patients. J Hepatol 2011; 54: 415-421.
    • (2011) J Hepatol , vol.54 , pp. 415-421
    • Sarrazin, C.1    Susser, S.2    Doehring, A.3
  • 46
    • 79952214262 scopus 로고    scopus 로고
    • IL28B genetic variation and treatment response in patients with hepatitis C virus genotype 3 infection
    • Moghaddam A, Melum E, Reinton N, et al. IL28B genetic variation and treatment response in patients with hepatitis C virus genotype 3 infection. Hepatology 2011; 53: 746-754.
    • (2011) Hepatology , vol.53 , pp. 746-754
    • Moghaddam, A.1    Melum, E.2    Reinton, N.3
  • 47
    • 77951880384 scopus 로고    scopus 로고
    • Association of a single nucleotide polymorphism near the interleukin-28B gene with response to hepatitis C therapy in HIV/hepatitis C virus-coinfected patients
    • Rallón NI, Naggie S, Benito JM, et al. Association of a single nucleotide polymorphism near the interleukin-28B gene with response to hepatitis C therapy in HIV/hepatitis C virus-coinfected patients. AIDS 2010; 24: F23-29.
    • (2010) AIDS , vol.24
    • Rallón, N.I.1    Naggie, S.2    Benito, J.M.3
  • 48
    • 79751511058 scopus 로고    scopus 로고
    • Genetic variation in IL28B and treatment-induced clearance of hepatitis C virus in HIVpositive patients with acute and chronic hepatitis C
    • Nattermann J, Vogel M, Nischalke HD, et al. Genetic variation in IL28B and treatment-induced clearance of hepatitis C virus in HIVpositive patients with acute and chronic hepatitis C. J Infect Dis 2011; 203: 595-601.
    • (2011) J Infect Dis , vol.203 , pp. 595-601
    • Nattermann, J.1    Vogel, M.2    Nischalke, H.D.3
  • 49
    • 80053928948 scopus 로고    scopus 로고
    • For the Aids Clinical Trials Group A5178 Study Team. IL28B Alleles Exert an Additive Dose Effect When Applied to HCVHIV Coinfected Persons Undergoing Peginterferon and Ribavirin Therapy
    • Abu Dayyeh BK, Gupta N, Sherman KE, de Bakker PI, Chung RT; For the Aids Clinical Trials Group A5178 Study Team. IL28B Alleles Exert an Additive Dose Effect When Applied to HCVHIV Coinfected Persons Undergoing Peginterferon and Ribavirin Therapy. PLoS One 2011; 6: e25753.
    • (2011) PLoS One , vol.6
    • Abu Dayyeh, B.K.1    Gupta, N.2    Sherman, K.E.3    de Bakker, P.I.4    Chung, R.T.5
  • 50
    • 79952655262 scopus 로고    scopus 로고
    • Interleukin-28B polymorphisms are associated with hepatitis C virus clearance and viral load in a HIV-1-infected cohort
    • Clausen LN, Weis N, Astvad K, et al. Interleukin-28B polymorphisms are associated with hepatitis C virus clearance and viral load in a HIV-1-infected cohort. J Viral Hepat 2011; 18: e66-74.
    • (2011) J Viral Hepat , vol.18
    • Clausen, L.N.1    Weis, N.2    Astvad, K.3
  • 51
    • 85027947842 scopus 로고    scopus 로고
    • Impact of IL28B polymorphisms on response to peginterferon and ribavirin in HIV-hepatitis C viruscoinfected patients with prior nonresponse or relapse
    • Labarga P, Barreiro P, Mira JA, et al., Impact of IL28B polymorphisms on response to peginterferon and ribavirin in HIV-hepatitis C viruscoinfected patients with prior nonresponse or relapse. AIDS 2011; 25: 1131-1133.
    • (2011) AIDS , vol.25 , pp. 1131-1133
    • Labarga, P.1    Barreiro, P.2    Mira, J.A.3
  • 52
    • 85027947842 scopus 로고    scopus 로고
    • Impact of IL28B Polymorphisms on Response to Peginterferon plus Ribavirin in HIV-HCV Coinfected Patients with Prior Non-Response or Relapse
    • Apr 18. [Epub ahead of print]
    • Labarga P, Barreiro P, Mira JA, et al, Impact of IL28B Polymorphisms on Response to Peginterferon plus Ribavirin in HIV-HCV Coinfected Patients with Prior Non-Response or Relapse. AIDS 2011 Apr 18. [Epub ahead of print]
    • (2011) AIDS
    • Labarga, P.1    Barreiro, P.2    Mira, J.A.3
  • 53
    • 77957825574 scopus 로고    scopus 로고
    • Prediction of response to pegylated interferon plus ribavirin by IL28B gene variation in patients coinfected with HIV and hepatitis C virus
    • Pineda JA, Caruz A, Rivero A, et al., Prediction of response to pegylated interferon plus ribavirin by IL28B gene variation in patients coinfected with HIV and hepatitis C virus. Clin Infect Dis 2010; 51: 788-795.
    • (2010) Clin Infect Dis , vol.51 , pp. 788-795
    • Pineda, J.A.1    Caruz, A.2    Rivero, A.3
  • 54
    • 77951880384 scopus 로고    scopus 로고
    • Association of a single nucleotide polymorphism near the interleukin-28B gene with response to hepatitis C therapy in HIV/hepatitis C virus-coinfected patients
    • Rallón NI, Naggie S, Benito JM, et al. Association of a single nucleotide polymorphism near the interleukin-28B gene with response to hepatitis C therapy in HIV/hepatitis C virus-coinfected patients. AIDS 2010; 24: F23-29.
    • (2010) AIDS , vol.24
    • Rallón, N.I.1    Naggie, S.2    Benito, J.M.3
  • 55
    • 85027955533 scopus 로고    scopus 로고
    • IL28B gene polymorphisms and viral kinetics in HIV/hepatitis C virus-coinfected patients treated with pegylated interferon and ribavirin
    • Rallón NI, Soriano V, Naggie S, et al. IL28B gene polymorphisms and viral kinetics in HIV/hepatitis C virus-coinfected patients treated with pegylated interferon and ribavirin. AIDS 2011; 25: 1025-1033.
    • (2011) AIDS , vol.25 , pp. 1025-1033
    • Rallón, N.I.1    Soriano, V.2    Naggie, S.3
  • 56
    • 77949831342 scopus 로고    scopus 로고
    • Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: A genomewide association study
    • Rauch A, Kutalik Z, Descombes P, et al. Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genomewide association study. Gastroenterology 2010; 138: 1338-1345, 1345. e1-7.
    • (1345) Gastroenterology 2010; 138: 1338-1345
    • Rauch, A.1    Kutalik, Z.2    Descombes, P.3
  • 57
    • 84861097898 scopus 로고    scopus 로고
    • Association between the IL28B genotype and hepatitis C viral kinetics in the early days of treatment with pegylated interferon plus ribavirin in HIV/HCV co-infected patients with genotype 1 or 4
    • Oct 11. [Epub ahead of print]
    • Rivero-Juárez A, Camacho Espejo A, Perez-Camacho I, et al. Association between the IL28B genotype and hepatitis C viral kinetics in the early days of treatment with pegylated interferon plus ribavirin in HIV/HCV co-infected patients with genotype 1 or 4. J Antimicrob Chemother 2011 Oct 11. [Epub ahead of print]
    • (2011) J Antimicrob Chemother
    • Rivero-Juárez, A.1    Camacho Espejo, A.2    Perez-Camacho, I.3
  • 58
    • 78649619461 scopus 로고    scopus 로고
    • IL28B polymorphism does not determine outcomes of hepatitis B virus or HIV infection
    • Martin MP, Qi Y, Goedert JJ, et al. IL28B polymorphism does not determine outcomes of hepatitis B virus or HIV infection. J Infect Dis 2010; 202: 1749-1753.
    • (2010) J Infect Dis , vol.202 , pp. 1749-1753
    • Martin, M.P.1    Qi, Y.2    Goedert, J.J.3
  • 59
    • 80052232595 scopus 로고    scopus 로고
    • IL28B genotype does not correlate with HIV control in African Americans
    • Sajadi MM, Shakeri N, Talwani R, et al. IL28B genotype does not correlate with HIV control in African Americans. Clin Transl Sci 2011; 4: 282-284.
    • (2011) Clin Transl Sci , vol.4 , pp. 282-284
    • Sajadi, M.M.1    Shakeri, N.2    Talwani, R.3
  • 60
    • 34548134145 scopus 로고    scopus 로고
    • A whole-genome association study of major determinants for host control of HIV-1
    • Fellay J, Shianna KV, Ge D, et al. A whole-genome association study of major determinants for host control of HIV-1. Science 2007; 317: 944-947.
    • (2007) Science , vol.317 , pp. 944-947
    • Fellay, J.1    Shianna, K.V.2    Ge, D.3
  • 61
    • 84055198778 scopus 로고    scopus 로고
    • Serum Level of IP-10 Increases Predictive Value of IL28B Polymorphisms for Spontaneous Clearance of Acute HCV Infection
    • Sep 28. [Epub ahead of print]
    • Beinhardt S, Aberle JH, Strasser M, et al. Serum Level of IP-10 Increases Predictive Value of IL28B Polymorphisms for Spontaneous Clearance of Acute HCV Infection. Gastroenterology 2011 Sep 28. [Epub ahead of print]
    • (2011) Gastroenterology
    • Beinhardt, S.1    Aberle, J.H.2    Strasser, M.3
  • 62
    • 78751492246 scopus 로고    scopus 로고
    • Quantitation of pretreatment serum interferon-gamma-inducible protein-10 improves the predictive value of an IL28B gene polymorphism for hepatitis C treatment response
    • Darling JM, Aerssens J, Fanning G, et al. Quantitation of pretreatment serum interferon-gamma-inducible protein-10 improves the predictive value of an IL28B gene polymorphism for hepatitis C treatment response. Hepatology 2011; 53: 14-22.
    • (2011) Hepatology , vol.53 , pp. 14-22
    • Darling, J.M.1    Aerssens, J.2    Fanning, G.3
  • 63
    • 79954797695 scopus 로고    scopus 로고
    • IL28B polymorphisms, IP-10 and viral load predict virological response to therapy in chronic hepatitis C
    • Fattovich G, Covolo L, Bibert S, et al. IL28B polymorphisms, IP-10 and viral load predict virological response to therapy in chronic hepatitis C. Aliment Pharmacol Ther 2011; 33: 1162-1172.
    • (2011) Aliment Pharmacol Ther , vol.33 , pp. 1162-1172
    • Fattovich, G.1    Covolo, L.2    Bibert, S.3
  • 64
    • 79952097683 scopus 로고    scopus 로고
    • Response prediction in chronic hepatitis C by assessment of IP-10 and IL28B-related single nucleotide polymorphisms
    • Lagging M, Askarieh G, Negro F, et al. Response prediction in chronic hepatitis C by assessment of IP-10 and IL28B-related single nucleotide polymorphisms. PLoS One 2011; 6: e17232.
    • (2011) PLoS One , vol.6
    • Lagging, M.1    Askarieh, G.2    Negro, F.3
  • 65
    • 80052252330 scopus 로고    scopus 로고
    • Serum interleukin (IL)-10 and IL-12 levels and IL28B gene polymorphisms: Pretreatment prediction of treatment failure in chronic hepatitis C
    • Umemura T, Joshita S, Yoneda S, et al. Serum interleukin (IL)-10 and IL-12 levels and IL28B gene polymorphisms: pretreatment prediction of treatment failure in chronic hepatitis C. Antivir Ther 2011; 16: 1073-1080.
    • (2011) Antivir Ther , vol.16 , pp. 1073-1080
    • Umemura, T.1    Joshita, S.2    Yoneda, S.3
  • 66
    • 79955040564 scopus 로고    scopus 로고
    • Innate immune genes synergize to predict increased risk of chronic disease in hepatitis C virus infection
    • Dring MM, Morrison MH, McSharry BP, et al. Innate immune genes synergize to predict increased risk of chronic disease in hepatitis C virus infection. Proc Natl Acad Sci U S A 2011; 108: 5736-5741.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 5736-5741
    • Dring, M.M.1    Morrison, M.H.2    McSharry, B.P.3
  • 67
    • 80053326694 scopus 로고    scopus 로고
    • IL28B, HLA-C, and KIR variants additively predict response to therapy in chronic hepatitis C virus infection in a European Cohort: A cross-sectional study
    • Suppiah V, Gaudieri S, Armstrong NJ, et al. IL28B, HLA-C, and KIR variants additively predict response to therapy in chronic hepatitis C virus infection in a European Cohort: a cross-sectional study. PLoS Med 2011; 8: e1001092.
    • (2011) PLoS Med , vol.8
    • Suppiah, V.1    Gaudieri, S.2    Armstrong, N.J.3
  • 68
    • 80052161834 scopus 로고    scopus 로고
    • Do lambda-IFNs IL28A and IL28B act on human natural killer cells?
    • Krämer B, Eisenhardt M, Glässner A, et al. Do lambda-IFNs IL28A and IL28B act on human natural killer cells? Proc Natl Acad Sci U S A 2011; 108: E519-520.
    • (2011) Proc Natl Acad Sci U S A , vol.108
    • Krämer, B.1    Eisenhardt, M.2    Glässner, A.3
  • 69
    • 33744910591 scopus 로고    scopus 로고
    • Antitumor activity of IFN-lambda in murine tumor models
    • Sato A, Ohtsuki M, Hata M, Kobayashi E, Murakami T. Antitumor activity of IFN-lambda in murine tumor models. J Immunol 2006; 176: 7686-7694.
    • (2006) J Immunol , vol.176 , pp. 7686-7694
    • Sato, A.1    Ohtsuki, M.2    Hata, M.3    Kobayashi, E.4    Murakami, T.5
  • 70
    • 34247095694 scopus 로고    scopus 로고
    • IL-28 elicits antitumor responses against murine fibrosarcoma
    • Numasaki M, Tagawa M, Iwata F, et al. IL-28 elicits antitumor responses against murine fibrosarcoma. J Immunol 2007; 178: 5086-5098.
    • (2007) J Immunol , vol.178 , pp. 5086-5098
    • Numasaki, M.1    Tagawa, M.2    Iwata, F.3
  • 71
    • 79953733132 scopus 로고    scopus 로고
    • Complementary role of vitamin D deficiency and the interleukin-28B rs12979860 C/T polymorphism in predicting antiviral response in chronic hepatitis C
    • Bitetto D, Fattovich G, Fabris C, et al. Complementary role of vitamin D deficiency and the interleukin-28B rs12979860 C/T polymorphism in predicting antiviral response in chronic hepatitis C. Hepatology 2011; 53: 1118-1126.
    • (2011) Hepatology , vol.53 , pp. 1118-1126
    • Bitetto, D.1    Fattovich, G.2    Fabris, C.3
  • 72
    • 84055183844 scopus 로고    scopus 로고
    • Ribavirin pharmacokinetics and IL28B plus CYP27B1 SNPs as predictors of response to Peg-IFN/RBV treatment in HCV 1/4 infected patients
    • Sep 6. [Epub ahead of print]
    • D'Avolio A, Ciancio A, Siccardi M, et al. Ribavirin pharmacokinetics and IL28B plus CYP27B1 SNPs as predictors of response to Peg-IFN/RBV treatment in HCV 1/4 infected patients. Hepatology 2011 Sep 6. [Epub ahead of print]
    • (2011) Hepatology
    • D'avolio, A.1    Ciancio, A.2    Siccardi, M.3
  • 73
    • 79959977894 scopus 로고    scopus 로고
    • Low-density lipoprotein receptor genotyping enhances the predictive value of IL28B genotype in HIV/hepatitis C virus-coinfected patients
    • Pineda JA, Caruz A, Di Lello FA, et al. Low-density lipoprotein receptor genotyping enhances the predictive value of IL28B genotype in HIV/hepatitis C virus-coinfected patients. AIDS 2011; 25: 1415-1420.
    • (2011) AIDS , vol.25 , pp. 1415-1420
    • Pineda, J.A.1    Caruz, A.2    Di Lello, F.A.3
  • 74
    • 81355161417 scopus 로고    scopus 로고
    • The predictive value of IL28B gene polymorphism for spontaneous clearance in a single source outbreak cohort is limited in patients carrying the CCR5Delta32 mutation
    • Apr 13. [Epub ahead of print]
    • Nattermann J, Timm J, Nischalke HD, et al. The predictive value of IL28B gene polymorphism for spontaneous clearance in a single source outbreak cohort is limited in patients carrying the CCR5Delta32 mutation. J Hepatol 2011 Apr 13. [Epub ahead of print]
    • (2011) J Hepatol
    • Nattermann, J.1    Timm, J.2    Nischalke, H.D.3
  • 75
    • 65449171953 scopus 로고    scopus 로고
    • Telaprevir and peginterferon with or without ribavirin for chronic HCV infection
    • Hézode C, Forestier N, Dusheiko G, et al. Telaprevir and peginterferon with or without ribavirin for chronic HCV infection. N Engl J Med 2009; 360: 1839-1850.
    • (2009) N Engl J Med , vol.360 , pp. 1839-1850
    • Hézode, C.1    Forestier, N.2    Dusheiko, G.3
  • 76
    • 79959438789 scopus 로고    scopus 로고
    • Telaprevir for previously untreated chronic hepatitis C virus infection
    • Jacobson IM, McHutchison JG, Dusheiko G, et al., Telaprevir for previously untreated chronic hepatitis C virus infection. N Engl J Med 364: 2405-2416.
    • N Engl J Med , vol.364 , pp. 2405-2416
    • Jacobson, I.M.1    McHutchison, J.G.2    Dusheiko, G.3
  • 77
    • 65449152185 scopus 로고    scopus 로고
    • Telaprevir with peginterferon and ribavirin for chronic HCV genotype 1 infection
    • McHutchison JG, Everson GT, Gordon SC et al. Telaprevir with peginterferon and ribavirin for chronic HCV genotype 1 infection. N Engl J Med 2009; 360: 1827-1838.
    • (2009) N Engl J Med , vol.360 , pp. 1827-1838
    • McHutchison, J.G.1    Everson, G.T.2    Gordon, S.C.3
  • 78
    • 79953176289 scopus 로고    scopus 로고
    • Boceprevir for previously treated chronic HCV genotype 1 infection
    • Bacon BR, Gordon SC, Lawitz E, et al. Boceprevir for previously treated chronic HCV genotype 1 infection. N Engl J Med 2011; 364: 1207-1217.
    • (2011) N Engl J Med , vol.364 , pp. 1207-1217
    • Bacon, B.R.1    Gordon, S.C.2    Lawitz, E.3
  • 79
    • 79953173221 scopus 로고    scopus 로고
    • Boceprevir for untreated chronic HCV genotype 1 infection
    • Poordad F, McCone J Jr, Bacon BR, et al. Boceprevir for untreated chronic HCV genotype 1 infection. N Engl J Med 2011; 364: 1195-1206.
    • (2011) N Engl J Med , vol.364 , pp. 1195-1206
    • Poordad, F.1    McCone Jr., J.2    Bacon, B.R.3
  • 80
    • 79960449077 scopus 로고    scopus 로고
    • IL28B polymorphism predicts virologic response in patients with hepatitis C genoytpe 1 treated with Boceprevir (BOC) combination therapy
    • Poordad F, Gordon SC, et al. IL28B polymorphism predicts virologic response in patients with hepatitis C genoytpe 1 treated with Boceprevir (BOC) combination therapy. J Hepatol 2011; 54: S6.
    • (2011) J Hepatol , vol.54
    • Poordad, F.1    Gordon, S.C.2
  • 81
    • 79960447952 scopus 로고    scopus 로고
    • Similar SVR rates in IL28B CC, CT or TT prior relapser, partial- or null responder patients treated with telaprevir/peginterferon/ribavirin: Retrospective analysis of the REALIZE study
    • Pol S, Aerssens J, Zeuzem S, et al. Similar SVR rates in IL28B CC, CT or TT prior relapser, partial- or null responder patients treated with telaprevir/peginterferon/ribavirin: retrospective analysis of the REALIZE study. J Hepatol 2011; 54: S6-7.
    • (2011) J Hepatol , vol.54
    • Pol, S.1    Aerssens, J.2    Zeuzem, S.3
  • 82
    • 14744276042 scopus 로고    scopus 로고
    • Lambda interferon inhibits hepatitis B and C virus replication
    • Robek MD, Boyd BS, Chisari FV. Lambda interferon inhibits hepatitis B and C virus replication. J Virol 2005; 79: 3851-3854.
    • (2005) J Virol , vol.79 , pp. 3851-3854
    • Robek, M.D.1    Boyd, B.S.2    Chisari, F.V.3
  • 83
    • 77955873433 scopus 로고    scopus 로고
    • Phase 1b study of pegylated interferon lambda 1 with or without ribavirin in patients with chronic genotype 1 hepatitis C virus infection
    • Muir AJ, Shiffman ML, Zaman A, et al. Phase 1b study of pegylated interferon lambda 1 with or without ribavirin in patients with chronic genotype 1 hepatitis C virus infection. Hepatology 2010; 52: 822-832.
    • (2010) Hepatology , vol.52 , pp. 822-832
    • Muir, A.J.1    Shiffman, M.L.2    Zaman, A.3
  • 84
    • 57649148762 scopus 로고    scopus 로고
    • Interleukin-29 functions cooperatively with interferon to induce antiviral gene expression and inhibit hepatitis C virus replication
    • Pagliaccetti NE, Eduardo R, Kleinstein SH, Mu XJ, Bandi P, Robek MD. Interleukin-29 functions cooperatively with interferon to induce antiviral gene expression and inhibit hepatitis C virus replication. J Biol Chem 2008; 283: 30079-30089.
    • (2008) J Biol Chem , vol.283 , pp. 30079-30089
    • Pagliaccetti, N.E.1    Eduardo, R.2    Kleinstein, S.H.3    Mu, X.J.4    Bandi, P.5    Robek, M.D.6
  • 85
    • 33744492302 scopus 로고    scopus 로고
    • Interferon-lambda-treated dendritic cells specifically induce proliferation of FOXP3-expressing suppressor T cells
    • Mennechet FJ, Uzé G. Interferon-lambda-treated dendritic cells specifically induce proliferation of FOXP3-expressing suppressor T cells. Blood 2006; 107: 4417-4423.
    • (2006) Blood , vol.107 , pp. 4417-4423
    • Mennechet, F.J.1    Uzé, G.2
  • 86
    • 79955102638 scopus 로고    scopus 로고
    • Estimating the net contribution of interleukin-28B variation to spontaneous hepatitis C virus clearance
    • di Iulio J, Ciuffi A, Fitzmaurice K, et al. Estimating the net contribution of interleukin-28B variation to spontaneous hepatitis C virus clearance. Hepatology 2011; 53: 1446-1454.
    • (2011) Hepatology , vol.53 , pp. 1446-1454
    • Di Iulio, J.1    Ciuffi, A.2    Fitzmaurice, K.3
  • 87
    • 77955475888 scopus 로고    scopus 로고
    • Hepatic ISG expression is associated with genetic variation in interleukin 28B and the outcome of IFN therapy for chronic hepatitis C
    • Honda M, Sakai A, Yamashita T, et al. Hepatic ISG expression is associated with genetic variation in interleukin 28B and the outcome of IFN therapy for chronic hepatitis C. Gastroenterology 2010; 139: 499-509.
    • (2010) Gastroenterology , vol.139 , pp. 499-509
    • Honda, M.1    Sakai, A.2    Yamashita, T.3
  • 88
    • 78649608515 scopus 로고    scopus 로고
    • IL28B genotype is associated with differential expression of intrahepatic interferonstimulated genes in patients with chronic hepatitis C
    • Urban TJ, Thompson AJ, Bradrick SS, et al. IL28B genotype is associated with differential expression of intrahepatic interferonstimulated genes in patients with chronic hepatitis C. Hepatology 2010; 52: 1888-1896.
    • (2010) Hepatology , vol.52 , pp. 1888-1896
    • Urban, T.J.1    Thompson, A.J.2    Bradrick, S.S.3
  • 90
    • 79952305174 scopus 로고    scopus 로고
    • Interferon-induced gene expression is a stronger predictor of treatment response than IL28B genotype in patients with hepatitis C
    • Dill MT, Duong FH, Vogt JE, et al. Interferon-induced gene expression is a stronger predictor of treatment response than IL28B genotype in patients with hepatitis C. Gastroenterology 2011; 140: 1021-1031.
    • (2011) Gastroenterology , vol.140 , pp. 1021-1031
    • Dill, M.T.1    Duong, F.H.2    Vogt, J.E.3
  • 91
    • 78049469161 scopus 로고    scopus 로고
    • A polymorphism near IL28B is associated with spontaneous clearance, of acute hepatitis C virus and jaundice
    • Tillmann HL, Thompson AJ, Patel K, et al. A polymorphism near IL28B is associated with spontaneous clearance, of acute hepatitis C virus and jaundice. Gastroenterology 2010; 139:1586-1592.
    • (2010) Gastroenterology , vol.139 , pp. 1586-1592
    • Tillmann, H.L.1    Thompson, A.J.2    Patel, K.3
  • 92
    • 77957965687 scopus 로고    scopus 로고
    • Potential role for interleukin-28B genotype in treatment decision-making in recent hepatitis C virus infection
    • Grebely J, Petoumenos K, Hellard M, et al. Potential role for interleukin-28B genotype in treatment decision-making in recent hepatitis C virus infection. Hepatology 2010; 52: 1216-1224.
    • (2010) Hepatology , vol.52 , pp. 1216-1224
    • Grebely, J.1    Petoumenos, K.2    Hellard, M.3
  • 93
    • 79960453276 scopus 로고    scopus 로고
    • Clinical Practice Guidelines: Management of hepatitis C virus infection
    • European Association for the Study of the Liver
    • European Association for the Study of the Liver. Clinical Practice Guidelines: Management of hepatitis C virus infection. J Hepatol 2011; 55: 245-264.
    • (2011) J Hepatol , vol.55 , pp. 245-264
  • 94
    • 80054846451 scopus 로고    scopus 로고
    • Improved responses to pegylated interferon alfa-2b and ribavirin by individualizing treatment for 24-72 weeks
    • Sarrazin C, Schwendy S, Möller B, et al. Improved responses to pegylated interferon alfa-2b and ribavirin by individualizing treatment for 24-72 weeks. Gastroenterology 2010; 141: 1656-1664.
    • (2010) Gastroenterology , vol.141 , pp. 1656-1664
    • Sarrazin, C.1    Schwendy, S.2    Möller, B.3
  • 95
    • 78651236368 scopus 로고    scopus 로고
    • Interleukin 6 promoter polymorphisms influence the outcome of chronic hepatitis C
    • Cussigh A, Falleti E, Fabris C, et al. Interleukin 6 promoter polymorphisms influence the outcome of chronic hepatitis C. Immunogenetics 2011; 63: 33-41.
    • (2011) Immunogenetics , vol.63 , pp. 33-41
    • Cussigh, A.1    Falleti, E.2    Fabris, C.3
  • 96
    • 10744230051 scopus 로고    scopus 로고
    • IL-10 and TNF-alpha polymorphisms and the recovery from HCV infection
    • Lio D, Caruso C, Di Stefano R, et al. IL-10 and TNF-alpha polymorphisms and the recovery from HCV infection. Hum Immunol 2003; 64: 674-680.
    • (2003) Hum Immunol , vol.64 , pp. 674-680
    • Lio, D.1    Caruso, C.2    Di Stefano, R.3
  • 97
    • 21344454892 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms and haplotypes in the IL10 region associated with HCV clearance
    • Oleksyk TK, Thio CL, Truelove AL, et al. Single nucleotide polymorphisms and haplotypes in the IL10 region associated with HCV clearance. Genes Immun 2005; 6: 347-357.
    • (2005) Genes Immun , vol.6 , pp. 347-357
    • Oleksyk, T.K.1    Thio, C.L.2    Truelove, A.L.3
  • 98
    • 0032769836 scopus 로고    scopus 로고
    • Interleukin-10 promoter polymorphism predicts initial response of chronic hepatitis C to interferon alfa
    • Edwards-Smith CJ, Jonsson JR, Purdie DM, Bansal A, Shorthouse C, Powell EE. Interleukin-10 promoter polymorphism predicts initial response of chronic hepatitis C to interferon alfa. Hepatology 1999; 30: 526-530.
    • (1999) Hepatology , vol.30 , pp. 526-530
    • Edwards-Smith, C.J.1    Jonsson, J.R.2    Purdie, D.M.3    Bansal, A.4    Shorthouse, C.5    Powell, E.E.6
  • 99
    • 18644384434 scopus 로고    scopus 로고
    • Polymorphisms in the IL-12B gene and outcome of HCV infection
    • Houldsworth A, Metzner M, Rossol S, et al. Polymorphisms in the IL-12B gene and outcome of HCV infection. J Interferon Cytokine Res 2005; 25: 271-276.
    • (2005) J Interferon Cytokine Res , vol.25 , pp. 271-276
    • Houldsworth, A.1    Metzner, M.2    Rossol, S.3
  • 100
    • 4644269525 scopus 로고    scopus 로고
    • Influence of interleukin 12B (IL12B) polymorphisms on spontaneous and treatment-induced recovery from hepatitis C virus infection
    • Mueller T, Mas-Marques A, Sarrazin C, et al. Influence of interleukin 12B (IL12B) polymorphisms on spontaneous and treatment-induced recovery from hepatitis C virus infection. J Hepatol 2004; 41: 652-658.
    • (2004) J Hepatol , vol.41 , pp. 652-658
    • Mueller, T.1    Mas-Marques, A.2    Sarrazin, C.3
  • 101
    • 69249220140 scopus 로고    scopus 로고
    • Interleukin 18 promoter variants (-137G>C and -607C>A) in patients with chronic hepatitis C: Association with treatment response
    • Haas SL, Weiss C, Bugert P, et al. Interleukin 18 promoter variants (-137G>C and -607C>A) in patients with chronic hepatitis C: association with treatment response. J Clin Immunol 2009; 29: 620-628.
    • (2009) J Clin Immunol , vol.29 , pp. 620-628
    • Haas, S.L.1    Weiss, C.2    Bugert, P.3
  • 102
    • 54749149734 scopus 로고    scopus 로고
    • Regulatory polymorphisms in the interleukin-18 promoter are associated with hepatitis C virus clearance
    • An P, Thio CL, Kirk GD, Donfield S, Goedert JJ, Winkler CA. Regulatory polymorphisms in the interleukin-18 promoter are associated with hepatitis C virus clearance. J Infect Dis 2008; 198: 1159-1165.
    • (2008) J Infect Dis , vol.198 , pp. 1159-1165
    • An, P.1    Thio, C.L.2    Kirk, G.D.3    Donfield, S.4    Goedert, J.J.5    Winkler, C.A.6
  • 103
    • 33846486344 scopus 로고    scopus 로고
    • A functional SNP of interferongamma gene is important for interferon-alpha-induced and spontaneous recovery from hepatitis C virus infection
    • Huang Y, Yang H, Borg BB, et al. A functional SNP of interferongamma gene is important for interferon-alpha-induced and spontaneous recovery from hepatitis C virus infection. Proc Natl Acad Sci U S A 2007; 104: 985-990.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 985-990
    • Huang, Y.1    Yang, H.2    Borg, B.B.3
  • 104
    • 33646341219 scopus 로고    scopus 로고
    • Association of transforming growth factor-beta 1 functional polymorphisms with natural clearance of hepatitis C virus
    • Kimura T, Saito T, Yoshimura M, et al. Association of transforming growth factor-beta 1 functional polymorphisms with natural clearance of hepatitis C virus. J Infect Dis 2006; 193: 1371-1374.
    • (2006) J Infect Dis , vol.193 , pp. 1371-1374
    • Kimura, T.1    Saito, T.2    Yoshimura, M.3
  • 105
    • 29744442515 scopus 로고    scopus 로고
    • Tumor necrosis factoralpha promoter polymorphism at position -308 predicts response to combination therapy in hepatitis C virus infection
    • Dai CY, Chuang WL, Chang WY, et al. Tumor necrosis factoralpha promoter polymorphism at position -308 predicts response to combination therapy in hepatitis C virus infection. J Infect Dis 2006; 193: 98-101.
    • (2006) J Infect Dis , vol.193 , pp. 98-101
    • Dai, C.Y.1    Chuang, W.L.2    Chang, W.Y.3
  • 106
    • 79954669573 scopus 로고    scopus 로고
    • Vitamin D deficiency and a CYP27B1-1260 promoter polymorphism are associated with chronic hepatitis C and poor response to interferon-alfa based therapy
    • Lange CM, Bojunga J, Ramos-Lopez E, et al. Vitamin D deficiency and a CYP27B1-1260 promoter polymorphism are associated with chronic hepatitis C and poor response to interferon-alfa based therapy. J Hepatol 2011; 54: 887-893.
    • (2011) J Hepatol , vol.54 , pp. 887-893
    • Lange, C.M.1    Bojunga, J.2    Ramos-Lopez, E.3
  • 107
    • 0036083009 scopus 로고    scopus 로고
    • Frequency of the HIVprotective CC chemokine receptor 5-Delta32/Delta32 genotype is increased in hepatitis C
    • Woitas RP, Ahlenstiel G, Iwan A, et al. Frequency of the HIVprotective CC chemokine receptor 5-Delta32/Delta32 genotype is increased in hepatitis C. Gastroenterology 2002; 122: 1721-1728.
    • (2002) Gastroenterology , vol.122 , pp. 1721-1728
    • Woitas, R.P.1    Ahlenstiel, G.2    Iwan, A.3
  • 108
    • 10744232281 scopus 로고    scopus 로고
    • CC chemokine receptor 5 delta32 polymorphism in two independent cohorts of hepatitis C virus infected patients without hemophilia
    • Wasmuth HE, Werth A, Mueller T, et al. CC chemokine receptor 5 delta32 polymorphism in two independent cohorts of hepatitis C virus infected patients without hemophilia. J Mol Med (Berl) 2004; 82: 64-69.
    • (2004) J Mol Med (Berl) , vol.82 , pp. 64-69
    • Wasmuth, H.E.1    Werth, A.2    Mueller, T.3
  • 109
    • 3843075120 scopus 로고    scopus 로고
    • HLA and NK cell inhibitory receptor genes in resolving hepatitis C virus infection
    • Khakoo SI, Thio CL, Martin MP, et al. HLA and NK cell inhibitory receptor genes in resolving hepatitis C virus infection. Science 2004; 305: 872-874.
    • (2004) Science , vol.305 , pp. 872-874
    • Khakoo, S.I.1    Thio, C.L.2    Martin, M.P.3
  • 110
    • 72849120234 scopus 로고    scopus 로고
    • Effect of killer immunoglobulin-like receptors in the response to combined treatment in patients with chronic hepatitis C virus infection
    • Vidal-Castiñeira JR, López-Vázquez A, Díaz-Peña R, et al. Effect of killer immunoglobulin-like receptors in the response to combined treatment in patients with chronic hepatitis C virus infection. J Virol 2010; 84: 475-481.
    • (2010) J Virol , vol.84 , pp. 475-481
    • Vidal-Castiñeira, J.R.1    López-Vázquez, A.2    Díaz-Peña, R.3
  • 111
    • 77950607813 scopus 로고    scopus 로고
    • Natural killer cell receptor and HLA-C gene polymorphisms among patients with hepatitis C: A comparison between sustained virological responders and non-responders
    • Carneiro VL, Lemaire DC, Bendicho MT, et al. Natural killer cell receptor and HLA-C gene polymorphisms among patients with hepatitis C: a comparison between sustained virological responders and non-responders. Liver Int 2010; 30: 567-573.
    • (2010) Liver Int , vol.30 , pp. 567-573
    • Carneiro, V.L.1    Lemaire, D.C.2    Bendicho, M.T.3
  • 112
    • 3042715432 scopus 로고    scopus 로고
    • Distinct MHC class I and II alleles are associated with hepatitis C viral clearance, originating from a single source
    • McKiernan SM, Hagan R, Curry M, et al. Distinct MHC class I and II alleles are associated with hepatitis C viral clearance, originating from a single source. Hepatology 2004; 40: 108-114.
    • (2004) Hepatology , vol.40 , pp. 108-114
    • McKiernan, S.M.1    Hagan, R.2    Curry, M.3
  • 113
    • 34248207182 scopus 로고    scopus 로고
    • A comparative review of HLA associations with hepatitis B and C viral infections across globalpopulations
    • Singh R, Kaul R, Kaul A, Khan K. A comparative review of HLA associations with hepatitis B and C viral infections across globalpopulations. World J Gastroenterol 2007; 13: 1770-1787.
    • (2007) World J Gastroenterol , vol.13 , pp. 1770-1787
    • Singh, R.1    Kaul, R.2    Kaul, A.3    Khan, K.4
  • 114
    • 44849095839 scopus 로고    scopus 로고
    • Associations between the human MHC and sustained virologic response in the treatment of chronic hepatitis C virus infection
    • Rhodes SL, Erlich H, Im KA, et al. Associations between the human MHC and sustained virologic response in the treatment of chronic hepatitis C virus infection. Genes Immun 2008; 9: 328-333.
    • (2008) Genes Immun , vol.9 , pp. 328-333
    • Rhodes, S.L.1    Erlich, H.2    Im, K.A.3
  • 115
    • 31344474524 scopus 로고    scopus 로고
    • Human leukocyte antigen class II DQB1*0301, DRB1*1101 alleles and spontaneous clearance of hepatitis C virus infection: A meta-analysis
    • Hong X, Yu RB, Sun NX, Wang B, Xu YC, Wu GL. Human leukocyte antigen class II DQB1*0301, DRB1*1101 alleles and spontaneous clearance of hepatitis C virus infection: a meta-analysis. World J Gastroenterol 2005; 11: 7302-7307.
    • (2005) World J Gastroenterol , vol.11 , pp. 7302-7307
    • Hong, X.1    Yu, R.B.2    Sun, N.X.3    Wang, B.4    Xu, Y.C.5    Wu, G.L.6
  • 116
    • 79960035861 scopus 로고    scopus 로고
    • Importance of host genetic factors HLA and IL28B as predictors of response to pegylated interferon and ribavirin
    • de Rueda PM, López-Nevot MÁ, Sáenz-López P, et al. Importance of host genetic factors HLA and IL28B as predictors of response to pegylated interferon and ribavirin. Am J Gastroenterol 2011; 106: 1246-1254.
    • (2011) Am J Gastroenterol , vol.106 , pp. 1246-1254
    • de Rueda, P.M.1    López-Nevot, M.Á.2    Sáenz-López, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.