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Volumn 3, Issue 4, 2011, Pages 3726-3739

Infiltration of M2 tumor-associated macrophages in oral squamous cell carcinoma correlates with tumor malignancy

Author keywords

Alternatively activated macrophages; CD163; Immunohistochemical analysis; M2 macrophage; Oral squamous cell carcinoma; Tumor microenvironment; Tumor associated macrophage

Indexed keywords

B7 ANTIGEN; CD163 ANTIGEN; CD40 ANTIGEN; CD68 ANTIGEN;

EID: 84055193356     PISSN: None     EISSN: 20726694     Source Type: Journal    
DOI: 10.3390/cancers3043726     Document Type: Article
Times cited : (59)

References (53)
  • 3
    • 66149109235 scopus 로고    scopus 로고
    • Human papillomavirus and head and neck squamous cell carcinoma: Recent evidence and clinical implications
    • Hennessey, P.T.; Westra, W.H.; Califano, J.A. Human papillomavirus and head and neck squamous cell carcinoma: recent evidence and clinical implications. J. Dent. Res. 2009, 88, 300-306.
    • (2009) J. Dent. Res , vol.88 , pp. 300-306
    • Hennessey, P.T.1    Westra, W.H.2    Califano, J.A.3
  • 4
    • 0021564388 scopus 로고
    • The cell biology of macrophage activation
    • Adams, D.O.; Hamilton, T.A. The cell biology of macrophage activation. Annu. Rev. Immunol. 1984, 2, 283-318.
    • (1984) Annu. Rev. Immunol , vol.2 , pp. 283-318
    • Adams, D.O.1    Hamilton, T.A.2
  • 5
    • 0010505362 scopus 로고
    • Regulation of Diversity in Macrophage Activation
    • Lopez-Berestein, G., Klostergaard, J., Eds.; CRC Press: New York, NY, USA
    • Hamilton, T.A.; Ohmori, Y.; Narumi, S.; Tannenbaum, C.S. Regulation of Diversity in Macrophage Activation. In Mononuclear Phagocytes in Cell Biology; Lopez-Berestein, G., Klostergaard, J., Eds.; CRC Press: New York, NY, USA, 1993; pp. 47-70.
    • (1993) Mononuclear Phagocytes In Cell Biology , pp. 47-70
    • Hamilton, T.A.1    Ohmori, Y.2    Narumi, S.3    Tannenbaum, C.S.4
  • 6
    • 0036839143 scopus 로고    scopus 로고
    • Macrophage polarization: Tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
    • Mantovani, A.; Sozzani, S.; Locati, M.; Allavena, P.; Sica, A. Macrophage polarization: Tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol. 2002, 23, 549-555.
    • (2002) Trends Immunol , vol.23 , pp. 549-555
    • Mantovani, A.1    Sozzani, S.2    Locati, M.3    Allavena, P.4    Sica, A.5
  • 7
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages
    • Gordon, S. Alternative activation of macrophages. Nat. Rev. Immunol. 2003, 3, 23-35.
    • (2003) Nat. Rev. Immunol , vol.3 , pp. 23-35
    • Gordon, S.1
  • 8
    • 7244238190 scopus 로고    scopus 로고
    • CD163: A specific marker of macrophages in paraffin-embedded tissue samples
    • Lau, S.K.; Chu, P.G.; Weiss, L.M. CD163: A specific marker of macrophages in paraffin-embedded tissue samples. Am. J. Clin. Pathol. 2004, 122, 794-801.
    • (2004) Am. J. Clin. Pathol , vol.122 , pp. 794-801
    • Lau, S.K.1    Chu, P.G.2    Weiss, L.M.3
  • 9
    • 50249144131 scopus 로고    scopus 로고
    • Possible involvement of the M2 anti-inflammatory macrophage phenotype in growth of human gliomas
    • Komohara, Y.; Ohnishi, K.; Kuratsu, J.; Takeya, M. Possible involvement of the M2 anti-inflammatory macrophage phenotype in growth of human gliomas. J. Pathol. 2008, 216, 15-24.
    • (2008) J. Pathol , vol.216 , pp. 15-24
    • Komohara, Y.1    Ohnishi, K.2    Kuratsu, J.3    Takeya, M.4
  • 11
    • 10744224063 scopus 로고    scopus 로고
    • The degree of macrophage infiltration into the cancer cell nest is a significant predictor of survival in gastric cancer patients
    • Ohno, S.; Inagawa, H.; Dhar, D.K.; Fujii, T.; Ueda, S.; Tachibana, M.; Suzuki, N.; Inoue, M.; Soma, G.; Nagasue, N. The degree of macrophage infiltration into the cancer cell nest is a significant predictor of survival in gastric cancer patients. Anticancer Res. 2003, 23, 5015-5022.
    • (2003) Anticancer Res , vol.23 , pp. 5015-5022
    • Ohno, S.1    Inagawa, H.2    Dhar, D.K.3    Fujii, T.4    Ueda, S.5    Tachibana, M.6    Suzuki, N.7    Inoue, M.8    Soma, G.9    Nagasue, N.10
  • 12
    • 32644466544 scopus 로고    scopus 로고
    • Macrophage and mast-cell invasion of tumor cell islets confers a marked survival advantage in non-small-cell lung cancer
    • Welsh, T.J.; Green, R.H.; Richardson, D.; Waller, D.A.; O'Byrne, K.J.; Bradding, P. Macrophage and mast-cell invasion of tumor cell islets confers a marked survival advantage in non-small-cell lung cancer. J. Clin. Oncol. 2005, 23, 8959-8967.
    • (2005) J. Clin. Oncol , vol.23 , pp. 8959-8967
    • Welsh, T.J.1    Green, R.H.2    Richardson, D.3    Waller, D.A.4    O'Byrne, K.J.5    Bradding, P.6
  • 14
    • 77952937103 scopus 로고    scopus 로고
    • The M1 form of tumor-associated macrophages in non-small cell lung cancer is positively associated with survival time
    • Ma, J.; Liu, L.; Che, G.; Yu, N.; Dai, F.; You, Z. The M1 form of tumor-associated macrophages in non-small cell lung cancer is positively associated with survival time. BMC Cancer 2010, 10, 112.
    • (2010) BMC Cancer , vol.10 , pp. 112
    • Ma, J.1    Liu, L.2    Che, G.3    Yu, N.4    Dai, F.5    You, Z.6
  • 15
    • 58849166142 scopus 로고    scopus 로고
    • Macrophages within NSCLC tumour islets are predominantly of a cytotoxic M1 phenotype associated with extended survival
    • Ohri, C.M.; Shikotra, A.; Green, R.H.; Waller, D.A.; Bradding, P. Macrophages within NSCLC tumour islets are predominantly of a cytotoxic M1 phenotype associated with extended survival. Eur. Respir. J. 2009, 33, 118-126.
    • (2009) Eur. Respir. J , vol.33 , pp. 118-126
    • Ohri, C.M.1    Shikotra, A.2    Green, R.H.3    Waller, D.A.4    Bradding, P.5
  • 16
    • 0036834136 scopus 로고    scopus 로고
    • Infiltration of tumor-associated macrophages in human oral squamous cell carcinoma
    • Li, C.; Shintani, S.; Terakado, N.; Nakashiro, K.; Hamakawa, H. Infiltration of tumor-associated macrophages in human oral squamous cell carcinoma. Oncol. Rep. 2002, 9, 1219-1223.
    • (2002) Oncol. Rep , vol.9 , pp. 1219-1223
    • Li, C.1    Shintani, S.2    Terakado, N.3    Nakashiro, K.4    Hamakawa, H.5
  • 17
    • 77955258493 scopus 로고    scopus 로고
    • Association of macrophages with angiogenesis in oral verrucous and squamous cell carcinomas
    • El-Rouby, D.H. Association of macrophages with angiogenesis in oral verrucous and squamous cell carcinomas. J. Oral Pathol. Med. 2010, 39, 559-564.
    • (2010) J. Oral Pathol. Med , vol.39 , pp. 559-564
    • El-Rouby, D.H.1
  • 20
    • 0036214017 scopus 로고    scopus 로고
    • The B7 family of ligands and its receptors: New pathways for costimulation and inhibition of immune responses
    • Carreno, B.M.; Collins, M. The B7 family of ligands and its receptors: New pathways for costimulation and inhibition of immune responses. Annu. Rev. Immunol. 2002, 20, 29-53.
    • (2002) Annu. Rev. Immunol , vol.20 , pp. 29-53
    • Carreno, B.M.1    Collins, M.2
  • 21
    • 0025950146 scopus 로고
    • Selective induction of B7/BB-1 on interferon-gamma stimulated monocytes: A potential mechanism for amplification of T cell activation through the CD28 pathway
    • Freedman, A.S.; Freeman, G.J.; Rhynhart, K.; Nadler, L.M. Selective induction of B7/BB-1 on interferon-gamma stimulated monocytes: A potential mechanism for amplification of T cell activation through the CD28 pathway. Cell. Immunol. 1991, 137, 429-437.
    • (1991) Cell. Immunol , vol.137 , pp. 429-437
    • Freedman, A.S.1    Freeman, G.J.2    Rhynhart, K.3    Nadler, L.M.4
  • 22
    • 0001930725 scopus 로고    scopus 로고
    • Regulation of scavenger receptor CD163 expression in human monocytes and macrophages by pro- and antiinflammatory stimuli
    • Buechler, C.; Ritter, M.; Orso, E.; Langmann, T.; Klucken, J.; Schmitz, G. Regulation of scavenger receptor CD163 expression in human monocytes and macrophages by pro- and antiinflammatory stimuli. J. Leukoc. Biol. 2000, 67, 97-103.
    • (2000) J. Leukoc. Biol , vol.67 , pp. 97-103
    • Buechler, C.1    Ritter, M.2    Orso, E.3    Langmann, T.4    Klucken, J.5    Schmitz, G.6
  • 23
    • 4544246612 scopus 로고    scopus 로고
    • CD163: A regulated hemoglobin scavenger receptor with a role in the anti-inflammatory response
    • Moestrup, S.K.; Moller, H.J. CD163: A regulated hemoglobin scavenger receptor with a role in the anti-inflammatory response. Ann. Med. 2004, 36, 347-354.
    • (2004) Ann. Med , vol.36 , pp. 347-354
    • Moestrup, S.K.1    Moller, H.J.2
  • 24
    • 0347123433 scopus 로고    scopus 로고
    • Tumour-educated macrophages promote tumour progression and metastasis
    • Pollard, J.W. Tumour-educated macrophages promote tumour progression and metastasis. Nat. Rev. Cancer 2004, 4, 71-78.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 71-78
    • Pollard, J.W.1
  • 25
    • 24744454660 scopus 로고    scopus 로고
    • Macrophage infiltration and its prognostic implications in breast cancer: The relationship with VEGF expression and microvessel density
    • Tsutsui, S.; Yasuda, K.; Suzuki, K.; Tahara, K.; Higashi, H.; Era, S. Macrophage infiltration and its prognostic implications in breast cancer: the relationship with VEGF expression and microvessel density. Oncol. Rep. 2005, 14, 425-431.
    • (2005) Oncol. Rep , vol.14 , pp. 425-431
    • Tsutsui, S.1    Yasuda, K.2    Suzuki, K.3    Tahara, K.4    Higashi, H.5    Era, S.6
  • 26
    • 0034650833 scopus 로고    scopus 로고
    • Autocrine production of IL-10 mediates defective IL-12 production and NF-kappa B activation in tumor-associated macrophages
    • Sica, A.; Saccani, A.; Bottazzi, B.; Polentarutti, N.; Vecchi, A.; van Damme, J.; Mantovani, A. Autocrine production of IL-10 mediates defective IL-12 production and NF-kappa B activation in tumor-associated macrophages. J. Immunol. 2000, 164, 762-767.
    • (2000) J. Immunol , vol.164 , pp. 762-767
    • Sica, A.1    Saccani, A.2    Bottazzi, B.3    Polentarutti, N.4    Vecchi, A.5    van Damme, J.6    Mantovani, A.7
  • 28
    • 0025810425 scopus 로고
    • The role of macrophages in the regulation of primary tumor growth
    • Walter, S.; Govoni, D.; Bottazzi, B.; Mantovani, A. The role of macrophages in the regulation of primary tumor growth. Pathobiology 1991, 59, 239-242.
    • (1991) Pathobiology , vol.59 , pp. 239-242
    • Walter, S.1    Govoni, D.2    Bottazzi, B.3    Mantovani, A.4
  • 29
    • 0033903714 scopus 로고    scopus 로고
    • Significance of macrophage chemoattractant protein-1 in macrophage recruitment, angiogenesis, and survival in human breast cancer
    • Ueno, T.; Toi, M.; Saji, H.; Muta, M.; Bando, H.; Kuroi, K.; Koike, M.; Inadera, H.; Matsushima, K. Significance of macrophage chemoattractant protein-1 in macrophage recruitment, angiogenesis, and survival in human breast cancer. Clin. Cancer Res. 2000, 6, 3282-3289.
    • (2000) Clin. Cancer Res , vol.6 , pp. 3282-3289
    • Ueno, T.1    Toi, M.2    Saji, H.3    Muta, M.4    Bando, H.5    Kuroi, K.6    Koike, M.7    Inadera, H.8    Matsushima, K.9
  • 30
    • 39649120597 scopus 로고    scopus 로고
    • Tumor-associated leukemia inhibitory factor and IL-6 skew monocyte differentiation into tumor-associated macrophage-like cells
    • Duluc, D.; Delneste, Y.; Tan, F.; Moles, M.P.; Grimaud, L.; Lenoir, J.; Preisser, L.; Anegon, I.; Catala, L.; Ifrah, N. et al. Tumor-associated leukemia inhibitory factor and IL-6 skew monocyte differentiation into tumor-associated macrophage-like cells. Blood 2007, 110, 4319-4330.
    • (2007) Blood , vol.110 , pp. 4319-4330
    • Duluc, D.1    Delneste, Y.2    Tan, F.3    Moles, M.P.4    Grimaud, L.5    Lenoir, J.6    Preisser, L.7    Anegon, I.8    Catala, L.9    Ifrah, N.10
  • 31
    • 65349163532 scopus 로고    scopus 로고
    • Detection of M2 macrophages and colony-stimulating factor 1 expression in serous and mucinous ovarian epithelial tumors
    • Kawamura, K.; Komohara, Y.; Takaishi, K.; Katabuchi, H.; Takeya, M. Detection of M2 macrophages and colony-stimulating factor 1 expression in serous and mucinous ovarian epithelial tumors. Pathol. Int. 2009, 59, 300-305.
    • (2009) Pathol. Int , vol.59 , pp. 300-305
    • Kawamura, K.1    Komohara, Y.2    Takaishi, K.3    Katabuchi, H.4    Takeya, M.5
  • 32
    • 0026762988 scopus 로고
    • Interleukin 4 potently enhances murine macrophage mannose receptor activity: A marker of alternative immunologic macrophage activation
    • Stein, M.; Keshav, S.; Harris, N.; Gordon, S. Interleukin 4 potently enhances murine macrophage mannose receptor activity: A marker of alternative immunologic macrophage activation. J. Exp. Med. 1992, 176, 287-292.
    • (1992) J. Exp. Med , vol.176 , pp. 287-292
    • Stein, M.1    Keshav, S.2    Harris, N.3    Gordon, S.4
  • 33
    • 33845398215 scopus 로고    scopus 로고
    • Biochemical and functional characterization of three activated macrophage populations
    • Edwards, J.P.; Zhang, X.; Frauwirth, K.A.; Mosser, D.M. Biochemical and functional characterization of three activated macrophage populations. J. Leukoc. Biol. 2006, 80, 1298-1307.
    • (2006) J. Leukoc. Biol , vol.80 , pp. 1298-1307
    • Edwards, J.P.1    Zhang, X.2    Frauwirth, K.A.3    Mosser, D.M.4
  • 34
    • 0033039180 scopus 로고    scopus 로고
    • IL-10 expression is associated with the expression of platelet-derived endothelial cell growth factor and prognosis in oral and oropharyngeal carcinoma
    • Fujieda, S.; Sunaga, H.; Tsuzuki, H.; Fan, G.K.; Saito, H. IL-10 expression is associated with the expression of platelet-derived endothelial cell growth factor and prognosis in oral and oropharyngeal carcinoma. Cancer Lett. 1999, 136, 1-9.
    • (1999) Cancer Lett , vol.136 , pp. 1-9
    • Fujieda, S.1    Sunaga, H.2    Tsuzuki, H.3    Fan, G.K.4    Saito, H.5
  • 35
    • 0036254329 scopus 로고    scopus 로고
    • Immunohistochemical localization of interleukin-10 in human oral and pharyngeal carcinomas
    • Chandler, S.W.; Rassekh, C.H.; Rodman, S.M.; Ducatman, B.S. Immunohistochemical localization of interleukin-10 in human oral and pharyngeal carcinomas. Laryngoscope 2002, 112, 808-815.
    • (2002) Laryngoscope , vol.112 , pp. 808-815
    • Chandler, S.W.1    Rassekh, C.H.2    Rodman, S.M.3    Ducatman, B.S.4
  • 36
    • 24044437159 scopus 로고    scopus 로고
    • Dual role of VEGF family members in the pathogenesis of head and neck cancer (HNSCC): Possible link between angiogenesis and immune tolerance
    • Strauss, L.; Volland, D.; Kunkel, M.; Reichert, T.E. Dual role of VEGF family members in the pathogenesis of head and neck cancer (HNSCC): Possible link between angiogenesis and immune tolerance. Med. Sci. Monit. 2005, 11, BR280-BR292.
    • (2005) Med. Sci. Monit , vol.11
    • Strauss, L.1    Volland, D.2    Kunkel, M.3    Reichert, T.E.4
  • 38
    • 47949122227 scopus 로고    scopus 로고
    • Association of CCL2 with lymph node metastasis and macrophage infiltration in oral cavity and lip squamous cell carcinoma
    • Ferreira, F.O.; Ribeiro, F.L.; Batista, A.C.; Leles, C.R.; de Cassia Goncalves Alencar, R.; Silva, T.A. Association of CCL2 with lymph node metastasis and macrophage infiltration in oral cavity and lip squamous cell carcinoma. Tumour Biol. 2008, 29, 114-121.
    • (2008) Tumour Biol , vol.29 , pp. 114-121
    • Ferreira, F.O.1    Ribeiro, F.L.2    Batista, A.C.3    Leles, C.R.4    de Cassia, G.A.R.5    Silva, T.A.6
  • 39
    • 0038581774 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-independent constitutive activation of STAT3 in head and neck squamous cell carcinoma is mediated by the autocrine/paracrine stimulation of the interleukin 6/gp130 cytokine system
    • Sriuranpong, V.; Park, J.I.; Amornphimoltham, P.; Patel, V.; Nelkin, B.D.; Gutkind, J.S. Epidermal growth factor receptor-independent constitutive activation of STAT3 in head and neck squamous cell carcinoma is mediated by the autocrine/paracrine stimulation of the interleukin 6/gp130 cytokine system. Cancer Res. 2003, 63, 2948-2956.
    • (2003) Cancer Res , vol.63 , pp. 2948-2956
    • Sriuranpong, V.1    Park, J.I.2    Amornphimoltham, P.3    Patel, V.4    Nelkin, B.D.5    Gutkind, J.S.6
  • 41
    • 0033800768 scopus 로고    scopus 로고
    • Oral and skin keratinocytes are stimulated to secrete monocyte chemoattractant protein-1 by tumour necrosis factor-alpha and interferon-gamma
    • Li, J.; Farthing, P.M.; Thornhill, M.H. Oral and skin keratinocytes are stimulated to secrete monocyte chemoattractant protein-1 by tumour necrosis factor-alpha and interferon-gamma. J. Oral Pathol. Med. 2000, 29, 438-444.
    • (2000) J. Oral Pathol. Med , vol.29 , pp. 438-444
    • Li, J.1    Farthing, P.M.2    Thornhill, M.H.3
  • 42
    • 67651160649 scopus 로고    scopus 로고
    • CD4 T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages
    • DeNardo, D.G.; Barreto, J.B.; Andreu, P.; Vasquez, L.; Tawfik, D.; Kolhatkar, N.; Coussens, L.M. CD4 T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages. Cancer Cell 2009, 16, 91-102.
    • (2009) Cancer Cell , vol.16 , pp. 91-102
    • Denardo, D.G.1    Barreto, J.B.2    Andreu, P.3    Vasquez, L.4    Tawfik, D.5    Kolhatkar, N.6    Coussens, L.M.7
  • 47
    • 33947259319 scopus 로고    scopus 로고
    • Immunosuppressive strategies that are mediated by tumor cells
    • Rabinovich, G.A.; Gabrilovich, D.; Sotomayor, E.M. Immunosuppressive strategies that are mediated by tumor cells. Annu. Rev. Immunol. 2007, 25, 267-296.
    • (2007) Annu. Rev. Immunol , vol.25 , pp. 267-296
    • Rabinovich, G.A.1    Gabrilovich, D.2    Sotomayor, E.M.3
  • 49
    • 70349569569 scopus 로고    scopus 로고
    • Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired
    • Ahmadzadeh, M.; Johnson, L.A.; Heemskerk, B.; Wunderlich, J.R.; Dudley, M.E.; White, D.E.; Rosenberg, S.A. Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired. Blood 2009, 114, 1537-1544.
    • (2009) Blood , vol.114 , pp. 1537-1544
    • Ahmadzadeh, M.1    Johnson, L.A.2    Heemskerk, B.3    Wunderlich, J.R.4    Dudley, M.E.5    White, D.E.6    Rosenberg, S.A.7
  • 50
    • 37049020929 scopus 로고    scopus 로고
    • Differing phenotypes between intraepithelial and stromal lymphocytes in early-stage tongue cancer
    • Katou, F.; Ohtani, H.; Watanabe, Y.; Nakayama, T.; Yoshie, O.; Hashimoto, K. Differing phenotypes between intraepithelial and stromal lymphocytes in early-stage tongue cancer. Cancer Res. 2007, 67, 11195-11201.
    • (2007) Cancer Res , vol.67 , pp. 11195-11201
    • Katou, F.1    Ohtani, H.2    Watanabe, Y.3    Nakayama, T.4    Yoshie, O.5    Hashimoto, K.6
  • 51
    • 0029833732 scopus 로고    scopus 로고
    • Mechanisms of immune suppression in patients with head and neck cancer: Influence on the immune infiltrate of the cancer
    • Young, M.R.; Wright, M.A.; Lozano, Y.; Matthews, J.P.; Benefield, J.; Prechel, M.M. Mechanisms of immune suppression in patients with head and neck cancer: Influence on the immune infiltrate of the cancer. Int. J. Cancer 1996, 67, 333-338.
    • (1996) Int. J. Cancer , vol.67 , pp. 333-338
    • Young, M.R.1    Wright, M.A.2    Lozano, Y.3    Matthews, J.P.4    Benefield, J.5    Prechel, M.M.6


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