The role of cyclooxygenase-2-dependent signaling via cyclic AMP response element activation on aromatase up-regulation by o,p'-DDT in human breast cancer cells

Toxicology Letters

Volumn 198, Issue 3, 2010, Pages 331-341

  Han, Eun Hee ^a   Kim, Hyung Gyun ^a   Hwang, Yong Pil ^a   Choi, Jae Ho ^a,b   Im, Ji Hye ^a,b   Park, Bonghwan ^a   Yang, Ji Hye ^a   Jeong, Tae Cheon ^c   Jeong, Hye Gwang ^a  

^a Chungnam National University   (South Korea)

^b Chosun University   (South Korea)

^c Yeungnam University   (South Korea)

Author keywords

Aromatase; Breast cancer; COX 2; O,p' DDT

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 6 ISOPROPOXY 9 OXO 2 XANTHENECARBOXYLIC ACID; 7 [5 (4 BIPHENYLYLMETHOXY) 2 MORPHOLINO 3 OXOCYCLOPENTYL] 4 HEPTENOIC ACID; ACTIN; AROMATASE; CHLORPHENOTANE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLOOXYGENASE 2; FULVESTRANT; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PROSTAGLANDIN E2; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; CREBBP PROTEIN, HUMAN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; ENZYME INHIBITOR; ESTROGEN RECEPTOR; O,P'-DDT; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN E RECEPTOR 4; PTGER4 PROTEIN, HUMAN; RNA;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL STRAIN MCF 7; CONTROLLED STUDY; CYCLIC AMP RESPONSIVE ELEMENT; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME PHOSPHORYLATION; GENE EXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION; BIOSYNTHESIS; BREAST TUMOR; CHEMISTRY; DRUG EFFECTS; ENZYMOLOGY; FEMALE; GENETICS; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL LINE; WESTERN BLOTTING;

AROMATASE; BLOTTING, WESTERN; BREAST NEOPLASMS; CELL LINE, TUMOR; CREB-BINDING PROTEIN; CYCLOOXYGENASE 2; DDT; DINOPROSTONE; ENZYME ACTIVATION; ENZYME INHIBITORS; FEMALE; HUMANS; RECEPTORS, ESTROGEN; RECEPTORS, PROSTAGLANDIN E; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; SIGNAL TRANSDUCTION; RECEPTORS, PROSTAGLANDIN E, EP4 SUBTYPE;

EID: 83855165591     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2010.07.015     Document Type: Article

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