The activity of recombinant human neuroglobin as an antioxidant and free radical scavenger

Proteins: Structure, Function and Bioinformatics

Volumn 79, Issue 1, 2011, Pages 115-125

  Li, Weiguang ^a   Wu, Yonghong ^a   Ren, Changhong ^a   Lu, Yiming ^a   Gao, Yan ^a   Zheng, Xiaofei ^a   Zhang, Chenggang ^a  

^a BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

Author keywords

Antioxidant; Free radical scavenging; Neuroglobin; Reactive oxygen species

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 2,2' AZINO DI (3 ETHYL BENZTHIAZOLINE 6 SULFONIC ACID) CATION; ANTIOXIDANT; ASCORBIC ACID; FREE RADICAL; HEMOGLOBIN; HYDROGEN PEROXIDE; HYDROXYL RADICAL; REACTIVE OXYGEN METABOLITE; RECOMBINANT HUMAN NEUROGLOBIN; RECOMBINANT PROTEIN; SCAVENGER; SUPEROXIDE; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ARTICLE; HUMAN; IN VITRO STUDY; IRON CHELATION; NEUROPROTECTION; PRIORITY JOURNAL;

ANTIOXIDANTS; BIPHENYL COMPOUNDS; CHELATING AGENTS; FERROUS COMPOUNDS; FREE RADICAL SCAVENGERS; GLOBINS; HUMANS; HYDROGEN PEROXIDE; HYDROXYL RADICAL; NERVE TISSUE PROTEINS; OXIDATION-REDUCTION; PICRATES; PROTEIN BINDING; REACTIVE OXYGEN SPECIES; RECOMBINANT PROTEINS;

EID: 78649783156     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.22863     Document Type: Article

References (49)

1. Matxain JM, Padro D, Ristila M, Strid A, Eriksson LA. Evidence of high *OH radical quenching efficiency by vitamin B6. J Phys Chem B 2009; 113: 9629-9632.
2. Marzatico F, Cafe C. Oxygen radicals and other toxic oxygen metabolites as key mediators of the central nervous system tissue injury. Funct Neurol 1993; 8: 51-66.
3. Delanty N, Dichter MA. Oxidative injury in the nervous system. Acta Neurol Scand 1998; 98: 145-153.
4. Elias RJ, Kellerby SS, Decker EA. Antioxidant activity of proteins and peptides. Crit Rev Food Sci Nutr 2008; 48: 430-441.
5. Burmester T, Weich B, Reinhardt S, Hankeln T. A vertebrate globin expressed in the brain. Nature 2000; 407: 520-523.
6. Sun Y, Jin K, Mao XO, Zhu Y, Greenberg DA. Neuroglobin is up-regulated by and protects neurons from hypoxic-ischemic injury. Proc Natl Acad Sci USA 2001; 98: 15306-15311.
7. Herold S, Fago A, Weber RE, Dewilde S, Moens L. Reactivity studies of the Fe(III) and Fe(II)NO forms of human neuroglobin reveal a potential role against oxidative stress. J Biol Chem 2004; 279: 22841-22847.
8. Fordel E, Thijs L, Martinet W, Lenjou M, Laufs T, Van Bockstaele D, Moens L, Dewilde S. Neuroglobin and cytoglobin overexpression protects human SH-SY5Y neuroblastoma cells against oxidative stress-induced cell death. Neurosci Lett 2006; 410: 146-151.
9. Liu J, Yu Z, Guo S, Lee SR, Xing C, Zhang C, Gao Y, Nicholls DG, Lo EH, Wang X. Effects of neuroglobin overexpression on mitochondrial function and oxidative stress following hypoxia/reoxygenation in cultured neurons. J Neurosci Res 2009; 87: 164-170.
10. Garry DJ, Mammen PP. Molecular insights into the functional role of myoglobin. Adv Exp Med Biol 2007; 618: 181-193.
11. Orlowski S, Nowak W. Locally enhanced sampling molecular dynamics study of the dioxygen transport in human cytoglobin. J Mol Model 2007; 13: 715-723.
12. Wang X, Liu J, Zhu H, Tejima E, Tsuji K, Murata Y, Atochin DN, Huang PL, Zhang C, Lo EH. Effects of neuroglobin overexpression on acute brain injury and long-term outcomes after focal cerebral ischemia. Stroke 2008; 39: 1869-1874.
13. Burmester T, Hankeln T. What is the function of neuroglobin? J Exp Biol 2009; 212(Part 10): 1423-1428.
14. Nayak G, Prentice HM, Milton SL. Role of neuroglobin in regulating reactive oxygen species in the brain of the anoxia-tolerant turtle Trachemys scripta. J Neurochem 2009; 110: 603-612.
15. Li RC, Morris MW, Lee SK, Pouranfar F, Wang Y, Gozal D. Neuroglobin protects PC12 cells against oxidative stress. Brain Res 2008; 1190: 159-166.
16. Dewilde S, Kiger L, Burmester T, Hankeln T, Baudin-Creuza V, Aerts T, Marden MC, Caubergs R, Moens L. Biochemical characterization and ligand binding properties of neuroglobin, a novel member of the globin family. J Biol Chem 2001; 276: 38949-38955.
17. Wu YH, Wang, LH, Gao Y, Zhang CG. Expression, purification and identification of recombinant human neuroglobin. China Biotechnol 2009; 29: 1-6.
18. Re R, Pellegrini N, Proteggente A, Pannala A, Yang M, Rice-Evans C. Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radic Biol Med 1999; 26: 1231-1237.
19. Ates B, Abraham L, Ercal N. Antioxidant and free radical scavenging properties of N-acetylcysteine amide (NACA) and comparison with N-acetylcysteine (NAC). Free Radic Res 2008; 42: 372-377.
20. Childs R, Bardsley W. The steady-state kinetics of peroxidase with 2, 2'-azino-di-(3-ethyl-benzthiazoline-6-sulphonic acid) as chromogen. Biochem J 1975; 145: 93-103.
21. Sheih IC, Wu TK, Fang TJ. Antioxidant properties of a new antioxidative peptide from algae protein waste hydrolysate in different oxidation systems. Bioresour Technol 2009; 100: 3419-3425.
22. He Z, Sun X, Mei G, Yu S, Li N. Nonclassical secretion of human catalase on the surface of CHO cells is more efficient than classical secretion. Cell Biol Int 2008; 32: 367-373.
23. Yu WL, Zhao YP, Shu B. The radical scavenging activities of radix puerariae isoflavonoids: a chemiluminescence study. Food Chem 2004; 86: 525-529.
24. Carter P. Spectrophotometric determination of serum iron at the submicrogram level with a new reagent (ferrozine). Anal Biochem 1971; 40: 450-458.
25. Damen CW, Speijer H, Hermens WT, Schellens JH, Rosing H, Beijnen JH. The bioanalysis of trastuzumab in human serum using precipitate-enhanced ellipsometry. Anal Biochem 2009; 393: 73-79.
26. Gebicki S, Gebicki JM. Formation of peroxides in amino acids and proteins exposed to oxygen free radicals. Biochem J 1993; 289(Part 3): 743-749.
27. Blokhina O, Virolainen E, Fagerstedt KV. Antioxidants, oxidative damage and oxygen deprivation stress: a review. Ann Bot 2003; 91: 179-194.
28. Stohs SJ, Bagchi D. Oxidative mechanisms in the toxicity of metal ions. Free Radic Biol Med 1995; 18: 321-336.
29. Trandafir F, Hoogewijs D, Altieri F, Rivetti di Val Cervo P, Ramser K, Van Doorslaer S, Vanfleteren JR, Moens L, Dewilde S. Neuroglobin and cytoglobin as potential enzyme or substrate. Gene 2007; 398: 103-113.
30. Koshiishi I, Tsuchida K, Takajo T, Komatsu M. Radical scavenger can scavenge lipid allyl radicals complexed with lipoxygenase at lower oxygen content. Biochem J 2006; 395: 303-309.
31. Hernandez-Ledesma B, Hsieh CC, de Lumen BO. Antioxidant and anti-inflammatory properties of cancer preventive peptide lunasin in RAW 264.7 macrophages. Biochem Biophys Res Commun 2009; 390: 803-808.
32. Liu L, Xu H, Jiang H, Wang J, Song N, Xie J. Ghrelin prevents 1-methyl-4-phenylpyridinium ion-induced cytotoxicity through anti-oxidation and NF-kappaB modulation in MES23.5 cells. Exp Neurol 2010; 22: 25-29.
33. Yang H, Wang X, Liu X, Wu J, Liu C, Gong W, Zhao Z, Hong J, Lin D, Wang Y, Lai R. Antioxidant peptidomics reveals novel skin antioxidant system. Mol Cell Proteomics 2009; 8: 571-583.
34. Wu J, Wang Y, Liu H, Yang H, Ma D, Li J, Li D, Lai R, Yu H. Two immunoregulatory peptides with antioxidant activity from tick salivary glands. J Biol Chem 2010; 285: 16606-16613.
35. Tatzber F, Griebenow S, Wonisch W, Winkler R. Dual method for the determination of peroxidase activity and total peroxides-iodide leads to a significant increase of peroxidase activity in human sera. Anal Biochem 2003; 316: 147-153.
36. Standley PR, Mainwaring MG, Gotoh T, Vinogradov SN. The calcium, copper and zinc content of some annelid extracellular haemoglobins. Biochem J 1988; 249: 915-916.
37. Lebioda L, LaCount MW, Zhang E, Chen YP, Han K, Whitton MM, Lincoln DE, Woodin SA. An enzymatic globin from a marine worm. Nature 1999; 401: 445.
38. Schmidt M, Giessl A, Laufs T, Hankeln T, Wolfrum U, Burmester T. How does the eye breathe? Evidence for neuroglobin-mediated oxygen supply in the mammalian retina. J Biol Chem 2003; 278: 1932-1935.
39. Nicolis S, Monzani E, Ciaccio C, Ascenzi P, Moens L, Casella L. Reactivity and endogenous modification by nitrite and hydrogen peroxide: does human neuroglobin act only as a scavenger? Biochem J 2007; 407: 89-99.
40. Fordel E, Thijs L, Moens L, Dewilde S. Neuroglobin and cytoglobin expression in mice. Evidence for a correlation with reactive oxygen species scavenging. FEBS J 2007; 274: 1312-1317.
41. Giuffre A, Moschetti T, Vallone B, Brunori M. Neuroglobin: enzymatic reduction and oxygen affinity. Biochem Biophys Res Commun 2008; 367: 893-898.
42. Widmer CC, Pereira CP, Gehrig P, Vallelian F, Schoedon G, Buehler PW, Schaer DJ. Hemoglobin can attenuate hydrogen peroxide-induced oxidative stress by acting as an antioxidative peroxidase. Antioxid Redox Signal 2010; 12: 185-198.
43. Flogel U, Godecke A, Klotz LO, Schrader J. Role of myoglobin in the antioxidant defense of the heart. FASEB J 2004; 18: 1156-1158.
44. Giulivi C, Davies KJ. A novel antioxidant role for hemoglobin. The comproportionation of ferrylhemoglobin with oxyhemoglobin. J Biol Chem 1990; 265: 19453-19460.
45. Gabbianelli R, Santroni AM, Fedeli D, Kantar A, Falcioni G. Antioxidant activities of different hemoglobin derivatives. Biochem Biophys Res Commun 1998; 242: 560-564.
46. Privalle C, Talarico T, Keng T, DeAngelo J. Pyridoxalated hemoglobin polyoxyethylene: a nitric oxide scavenger with antioxidant activity for the treatment of nitric oxide-induced shock. Free Radic Biol Med 2000; 28: 1507-1517.
47. Finkel T. Reactive oxygen species and signal transduction. IUBMB Life 2001; 52: 3-6.
48. Antao ST, Duong TT, Aran R, Witting PK. Neuroglobin overexpression in cultured human neuronal cells protects against hydrogen peroxide insult via activating phosphoinositide-3 kinase and opening the mitochondrial K(ATP) channel. Antioxid Redox Signal 2010; 13: 769-781.
49. Venis S. Neuroglobin might protect brain cells during stroke. Lancet 2001; 358: 2055.