-
2
-
-
65549087101
-
Antiplatelet actions of statins and fibrates are mediated by PPARs
-
Ali FY, Armstrong PC, Dhanji AR, Tucker AT, Paul-Clark MJ, Mitchell JA, et al,. (2009). Antiplatelet actions of statins and fibrates are mediated by PPARs. Arterioscler Thromb Vasc Biol 29: 706-711.
-
(2009)
Arterioscler Thromb Vasc Biol
, vol.29
, pp. 706-711
-
-
Ali, F.Y.1
Armstrong, P.C.2
Dhanji, A.R.3
Tucker, A.T.4
Paul-Clark, M.J.5
Mitchell, J.A.6
-
3
-
-
33646558252
-
Clinical Perspectives of Statin-Induced Rhabdomyolysis
-
DOI 10.1016/j.amjmed.2006.02.007, PII S0002934306001847
-
Antons KA, Williams CD, Baker SK, Phillips PS, (2006). Clinical perspectives of statin-induced rhabdomyolysis. Am J Med 119: 400-409. (Pubitemid 44294467)
-
(2006)
American Journal of Medicine
, vol.119
, Issue.5
, pp. 400-409
-
-
Antons, K.A.1
Williams, C.D.2
Baker, S.K.3
Phillips, P.S.4
-
4
-
-
77952674092
-
The low dose combination of fenofibrate and rosiglitazone halts the progression of diabetes-induced experimental nephropathy
-
Arora MK, Reddy K, Balakumar P, (2010). The low dose combination of fenofibrate and rosiglitazone halts the progression of diabetes-induced experimental nephropathy. Eur J Pharmacol 636: 137-144.
-
(2010)
Eur J Pharmacol
, vol.636
, pp. 137-144
-
-
Arora, M.K.1
Reddy, K.2
Balakumar, P.3
-
5
-
-
77956918119
-
Multifarious molecular signaling cascades of cardiac hypertrophy: Can the muddy waters be cleared?
-
Balakumar P, Jagadeesh G, (2010). Multifarious molecular signaling cascades of cardiac hypertrophy: can the muddy waters be cleared? Pharmacol Res 62: 365-383.
-
(2010)
Pharmacol Res
, vol.62
, pp. 365-383
-
-
Balakumar, P.1
Jagadeesh, G.2
-
6
-
-
34548182594
-
PPAR dual agonists: Are they opening Pandora's Box?
-
DOI 10.1016/j.phrs.2007.03.002, PII S1043661807000503
-
Balakumar P, Rose M, Ganti SS, Krishan P, Singh M, (2007a). PPAR dual agonists: are they opening Pandora's Box? Pharmacol Res 56: 91-98. (Pubitemid 47304493)
-
(2007)
Pharmacological Research
, vol.56
, Issue.2
, pp. 91-98
-
-
Balakumar, P.1
Rose, M.2
Ganti, S.S.3
Krishan, P.4
Singh, M.5
-
7
-
-
34347333419
-
PPAR ligands: Are they potential agents for cardiovascular disorders?
-
DOI 10.1159/000102594
-
Balakumar P, Rose M, Singh M, (2007b). PPAR ligands: are they potential agents for cardiovascular disorders? Pharmacology 80: 1-10. (Pubitemid 47013361)
-
(2007)
Pharmacology
, vol.80
, Issue.1
, pp. 1-10
-
-
Balakumar, P.1
Rose, M.2
Singh, M.3
-
8
-
-
67349188030
-
Emerging role of PPAR ligands in the management of diabetic nephropathy
-
Balakumar P, Arora MK, Singh M, (2009). Emerging role of PPAR ligands in the management of diabetic nephropathy. Pharmacol Res 60: 170-173.
-
(2009)
Pharmacol Res
, vol.60
, pp. 170-173
-
-
Balakumar, P.1
Arora, M.K.2
Singh, M.3
-
10
-
-
3442877840
-
The protein kinase C signaling pathway regulates a molecular switch between transactivation and transrepression activity of the peroxisome proliferator-activated receptor α
-
DOI 10.1210/me.2003-0327
-
Blanquart C, Mansouri R, Paumelle R, Fruchart JC, Staels B, Glineur C, (2004). The protein kinase C signaling pathway regulates a molecular switch between transactivation and transrepression activity of the peroxisome proliferator-activated receptor alpha. Mol Endocrinol 18: 1906-1918. (Pubitemid 39006498)
-
(2004)
Molecular Endocrinology
, vol.18
, Issue.8
, pp. 1906-1918
-
-
Blanquart, C.1
Mansouri, R.2
Paumelle, R.3
Fruchart, J.-C.4
Staels, B.5
Glineur, C.6
-
11
-
-
77953794875
-
Pravastatin attenuates carboplatin-induced nephrotoxicity in rodents via peroxisome proliferator-activated receptor alpha-regulated heme oxygenase-1
-
Chen HH, Chen TW, Lin H, (2010). Pravastatin attenuates carboplatin-induced nephrotoxicity in rodents via peroxisome proliferator-activated receptor alpha-regulated heme oxygenase-1. Mol Pharmacol 78: 36-45.
-
(2010)
Mol Pharmacol
, vol.78
, pp. 36-45
-
-
Chen, H.H.1
Chen, T.W.2
Lin, H.3
-
12
-
-
43349084167
-
PPAR alpha activator fenofibrate regressed left ventricular hypertrophy and increased myocardium PPAR alpha expression in spontaneously hypertensive rats
-
Chen HJ, Chen JZ, Wang XX, Yu M, (2007). PPAR alpha activator fenofibrate regressed left ventricular hypertrophy and increased myocardium PPAR alpha expression in spontaneously hypertensive rats. Zhejiang Da Xue Xue Bao Yi Xue Ban 36: 470-476.
-
(2007)
Zhejiang da Xue Xue Bao Yi Xue Ban
, vol.36
, pp. 470-476
-
-
Chen, H.J.1
Chen, J.Z.2
Wang, X.X.3
Yu, M.4
-
13
-
-
33749339309
-
Angiotensin II-mediated oxidative stress and procollagen-1 expression in cardiac fibroblasts: Blockade by pravastatin and pioglitazone
-
DOI 10.1152/ajpheart.00341.2006
-
Chen J, Mehta JL, (2006). Angiotensin II-mediated oxidative stress and procollagen-1 expression in cardiac fibroblasts: blockade by pravastatin and pioglitazone. Am J Physiol Heart Circ Physiol 291: H1738-H1745. (Pubitemid 44497679)
-
(2006)
American Journal of Physiology - Heart and Circulatory Physiology
, vol.291
, Issue.4
-
-
Chen, J.1
Mehta, J.L.2
-
14
-
-
37849040502
-
Rosuvastatin increases vascular endothelial PPARgamma expression and corrects blood pressure variability in obese dyslipidaemic mice
-
Desjardins F, Sekkali B, Verreth W, Pelat M, De Keyzer D, Mertens A, et al,. (2008). Rosuvastatin increases vascular endothelial PPARgamma expression and corrects blood pressure variability in obese dyslipidaemic mice. Eur Heart J 29: 128-137.
-
(2008)
Eur Heart J
, vol.29
, pp. 128-137
-
-
Desjardins, F.1
Sekkali, B.2
Verreth, W.3
Pelat, M.4
De Keyzer, D.5
Mertens, A.6
-
15
-
-
1042286369
-
PPARα activator fenofibrate inhibits myocardial inflammation and fibrosis in angiotensin II-infused rats
-
DOI 10.1016/j.yjmcc.2003.11.004
-
Diep QN, Benkirane K, Amiri F, Cohn JS, Endemann D, Schiffrin EL, (2004). PPAR alpha activator fenofibrate inhibits myocardial inflammation and fibrosis in angiotensin II-infused rats. J Mol Cell Cardiol 36: 295-304. (Pubitemid 38202358)
-
(2004)
Journal of Molecular and Cellular Cardiology
, vol.36
, Issue.2
, pp. 295-304
-
-
Diep, Q.N.1
Benkirane, K.2
Amiri, F.3
Cohn, J.S.4
Endemann, D.5
Schiffrin, E.L.6
-
16
-
-
56249127895
-
Investigation of the vascular and pleiotropic effects of atorvastatin and pioglitazone in a population at high cardiovascular risk
-
Forst T, Wilhelm B, Pfützner A, Fuchs W, Lehmann U, Schaper F, et al,. (2008). Investigation of the vascular and pleiotropic effects of atorvastatin and pioglitazone in a population at high cardiovascular risk. Diab Vasc Dis Res 5: 298-303.
-
(2008)
Diab Vasc Dis Res
, vol.5
, pp. 298-303
-
-
Forst, T.1
Wilhelm, B.2
Pfützner, A.3
Fuchs, W.4
Lehmann, U.5
Schaper, F.6
-
17
-
-
42449117901
-
Reduction in blood pressure with statins: Results from the UCSD statin study, a randomized trial
-
DOI 10.1001/archinte.168.7.721
-
Golomb BA, Dimsdale JE, White HL, Ritchie JB, Criqui MH, (2008). Reduction in blood pressure with statins: results from the USCD Statin Study, a randomized trial. Arch Intern Med 168: 721-727. (Pubitemid 351563955)
-
(2008)
Archives of Internal Medicine
, vol.168
, Issue.7
, pp. 721-727
-
-
Golomb, B.A.1
Dimsdale, J.E.2
White, H.L.3
Ritchie, J.B.4
Criqui, M.H.5
-
18
-
-
0036186165
-
Atorvastatin activates PPAR-γ and attenuates the inflammatory response in human monocytes
-
Grip O, Janciauskiene S, Lindgren S, (2002). Atorvastatin activates PPAR-gamma and attenuates the inflammatory response in human monocytes. Inflamm Res 51: 58-62. (Pubitemid 34183624)
-
(2002)
Inflammation Research
, vol.51
, Issue.2
, pp. 58-62
-
-
Grip, O.1
Janciauskiene, S.2
Lindgren, S.3
-
19
-
-
13844272245
-
Effectiveness and tolerability of simvastatin plus fenofibrate for combined hyperlipidemia (the SAFARI trial)
-
DOI 10.1016/j.amjcard.2004.10.012
-
Grundy SM, Vega GL, Yuan Z, Battisti WP, Brady WE, Palmisano J, (2005). Effectiveness and tolerability of simvastatin plus fenofibrate for combined hyperlipidemia (the SAFARI trial). Am J Cardiol 95: 462-468. (Pubitemid 40247539)
-
(2005)
American Journal of Cardiology
, vol.95
, Issue.4
, pp. 462-468
-
-
Grundy, S.M.1
Vega, G.L.2
Yuan, Z.3
Battisti, W.P.4
Brady, W.E.5
Palmisano, J.6
-
20
-
-
78650822575
-
Pravastatin normalises peripheral cardiac sympathetic hyperactivity in the spontaneously hypertensive rat
-
Herring N, Lee CW, Sunderland N, Wright K, Paterson DJ, (2011). Pravastatin normalises peripheral cardiac sympathetic hyperactivity in the spontaneously hypertensive rat. J Mol Cell Cardiol 50: 99-106.
-
(2011)
J Mol Cell Cardiol
, vol.50
, pp. 99-106
-
-
Herring, N.1
Lee, C.W.2
Sunderland, N.3
Wright, K.4
Paterson, D.J.5
-
21
-
-
70350062074
-
Atorvastatin and fenofibrate increase apolipoprotein AV and decrease triglycerides by up-regulating peroxisome proliferator-activated receptor-alpha
-
Huang XS, Zhao SP, Bai L, Hu M, Zhao W, Zhang Q, (2009). Atorvastatin and fenofibrate increase apolipoprotein AV and decrease triglycerides by up-regulating peroxisome proliferator-activated receptor-alpha. Br J Pharmacol 158: 706-712.
-
(2009)
Br J Pharmacol
, vol.158
, pp. 706-712
-
-
Huang, X.S.1
Zhao, S.P.2
Bai, L.3
Hu, M.4
Zhao, W.5
Zhang, Q.6
-
22
-
-
80054777365
-
Statin reduced triglyceride level via activating peroxisome proliferator activated receptor α and upregulating apolipoprotein A5 in hypertriglyceridemic rats
-
Huang XS, Zhao SP, Bai L, Zhang Q, Hu M, Zhao W, (2010). Statin reduced triglyceride level via activating peroxisome proliferator activated receptor α and upregulating apolipoprotein A5 in hypertriglyceridemic rats. Zhonghua Xin Xue Guan Bing Za Zhi 38: 809-813.
-
(2010)
Zhonghua Xin Xue Guan Bing Za Zhi
, vol.38
, pp. 809-813
-
-
Huang, X.S.1
Zhao, S.P.2
Bai, L.3
Zhang, Q.4
Hu, M.5
Zhao, W.6
-
23
-
-
0034647595
-
Lipophilic HMG-CoA reductase inhibitor has an anti-inflammatory effect: Reduction of MRNA levels for interleukin-1β, interleukin-6, cyclooxygenase- 2, and p22phox by regulation of peroxisome proliferator-activated receptor α (PPARα) in primary endothelial cells
-
DOI 10.1016/S0024-3205(00)00680-9, PII S0024320500006809
-
Inoue I, Goto S, Mizotani K, Awata T, Mastunaga T, Kawai S, et al,. (2000). Lipophilic HMG-CoA reductase inhibitor has an anti-inflammatory effect: reduction of MRNA levels for interleukin-1beta, interleukin-6, cyclooxygenase-2, and p22phox by regulation of peroxisome proliferator-activated receptor alpha (PPARalpha) in primary endothelial cells. Life Sci 67: 863-876. (Pubitemid 30491080)
-
(2000)
Life Sciences
, vol.67
, Issue.8
, pp. 863-876
-
-
Inoue, I.1
Goto, S.-I.2
Mizotani, K.3
Awata, T.4
Mastunaga, T.5
Kawai, S.-I.6
Nakajima, T.7
Hokari, S.8
Komoda, T.9
Katayama, S.10
-
24
-
-
44049091020
-
Clinical efficacy and safety of statins in managing cardiovascular risk
-
Kapur NK, Musunuru K, (2008). Clinical efficacy and safety of statins in managing cardiovascular risk. Vasc Health Risk Manag 4: 341-353. (Pubitemid 351711963)
-
(2008)
Vascular Health and Risk Management
, vol.4
, Issue.2
, pp. 341-353
-
-
Kapur, N.K.1
Musunuru, K.2
-
25
-
-
77951601655
-
Thiazolidinedione drugs and cardiovascular risks: A science advisory from the American Heart Association and American College of Cardiology Foundation
-
Kaul S, Bolger AF, Herrington D, Giugliano RP, Eckel RH, (2010). Thiazolidinedione drugs and cardiovascular risks: a science advisory from the American Heart Association and American College of Cardiology Foundation. Circulation 121: 1868-1877.
-
(2010)
Circulation
, vol.121
, pp. 1868-1877
-
-
Kaul, S.1
Bolger, A.F.2
Herrington, D.3
Giugliano, R.P.4
Eckel, R.H.5
-
26
-
-
77956342929
-
The novel role of fenofibrate in preventing nicotine and sodium arsenite-induced vascular endothelial dysfunction in the rat
-
Kaur J, Reddy K, Balakumar P, (2010). The novel role of fenofibrate in preventing nicotine and sodium arsenite-induced vascular endothelial dysfunction in the rat. Cardiovasc Toxicol 10: 227-238.
-
(2010)
Cardiovasc Toxicol
, vol.10
, pp. 227-238
-
-
Kaur, J.1
Reddy, K.2
Balakumar, P.3
-
27
-
-
44949131820
-
Lovastatin interferes with the infarct size-limiting effect of ischemic preconditioning and postconditioning in rat hearts
-
Kocsis GF, Pipis J, Fekete V, Kovács-Simon A, Odendaal L, Molnár E, et al,. (2008). Lovastatin interferes with the infarct size-limiting effect of ischemic preconditioning and postconditioning in rat hearts. Am J Physiol Heart Circ Physiol 294: H2406-H2409.
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.294
-
-
Kocsis, G.F.1
Pipis, J.2
Fekete, V.3
Kovács-Simon, A.4
Odendaal, L.5
Molnár, E.6
-
28
-
-
18944381282
-
Additive beneficial effects of fenofibrate combined with atorvastatin in the treatment of combined hyperlipidemia
-
DOI 10.1016/j.jacc.2005.02.052, PII S0735109705004894
-
Koh KK, Quon MJ, Han SH, Chung WJ, Ahn JY, Seo YH, et al,. (2005). Additive beneficial effects of fenofibrate combined with atorvastatin in the treatment of combined hyperlipidemia. J Am Coll Cardiol 45: 1649-1653. (Pubitemid 40704501)
-
(2005)
Journal of the American College of Cardiology
, vol.45
, Issue.10
, pp. 1649-1653
-
-
Koh, K.K.1
Quon, M.J.2
Han, S.H.3
Chung, W.-J.4
Ahn, J.Y.5
Seo, Y.-H.6
Choi, I.S.7
Shin, E.K.8
-
29
-
-
53849127533
-
Effects of pioglitazone and/or simvastatin on low density lipoprotein subfractions in non-diabetic patients with high cardiovascular risk: A sub-analysis from the PIOSTAT study
-
Leonhardt W, Pfützner A, Müller J, Pietzsch J, Forst T, Karagiannis E, et al,. (2008). Effects of pioglitazone and/or simvastatin on low density lipoprotein subfractions in non-diabetic patients with high cardiovascular risk: a sub-analysis from the PIOSTAT study. Atherosclerosis 201: 155-162.
-
(2008)
Atherosclerosis
, vol.201
, pp. 155-162
-
-
Leonhardt, W.1
Pfützner, A.2
Müller, J.3
Pietzsch, J.4
Forst, T.5
Karagiannis, E.6
-
30
-
-
84871406275
-
Effect of statin therapy on mortality in patients with non-ischemic dilated cardiomyopathy
-
Li X, Liu XP, Liu XH, Du X, Kang JP, Lü Q, et al,. (2010). Effect of statin therapy on mortality in patients with non-ischemic dilated cardiomyopathy. Zhonghua Yi Xue Za Zhi 90: 1974-1977.
-
(2010)
Zhonghua Yi Xue Za Zhi
, vol.90
, pp. 1974-1977
-
-
Li, X.1
Liu, X.P.2
Liu, X.H.3
Du, X.4
Kang, J.P.5
Lü, Q.6
-
31
-
-
38549086358
-
Effects of atorvastatin on expression of peroxisome proliferation activated receptor Y in unilateral ureteral obstruction in rats
-
Liu B, Chen M, Peng HX, Zhang C, Ou ST, (2007). Effects of atorvastatin on expression of peroxisome proliferation activated receptor gamma in unilateral ureteral obstruction in rats. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 19: 739-741. (Pubitemid 351148241)
-
(2007)
Chinese Critical Care Medicine
, vol.19
, Issue.12
, pp. 739-741
-
-
Liu, B.1
Chen, M.2
Peng, H.-X.3
Zhang, C.4
Ou, S.-T.5
-
32
-
-
0035584083
-
Effect of Pravastatin on endothelial function in patients with coronary artery disease (cholesterol-independent effect of Pravastatin)
-
DOI 10.1016/S0002-9149(01)02090-2, PII S0002914901020902
-
Masumoto A, Hirooka Y, Hironaga K, Eshima K, Setoguchi S, Egashira K, et al,. (2001). Effect of pravastatin on endothelial function in patients with coronary artery disease (cholesterol-independent effect of pravastatin). Am J Cardiol 88: 1291-1294. (Pubitemid 33132098)
-
(2001)
American Journal of Cardiology
, vol.88
, Issue.11
, pp. 1291-1294
-
-
Masumoto, A.1
Hirooka, Y.2
Hironaga, K.3
Eshima, K.4
Setoguchi, S.5
Egashira, K.6
Takeshita, A.7
-
33
-
-
29444454732
-
Statin-induced myositis: A commonly encountered or rare side effect?
-
Mukhtar RY, Reckless JP, (2005). Statin-induced myositis: a commonly encountered or rare side effect? Curr Opin Lipidol 16: 640-647. (Pubitemid 43012162)
-
(2005)
Current Opinion in Lipidology
, vol.16
, Issue.6
, pp. 640-647
-
-
Mukhtar, R.Y.A.1
Reckless, J.P.D.2
-
34
-
-
33747118373
-
Benefit of adding pioglitazone to statin therapy in non-diabetic patients with the metabolic syndrome
-
Murdock DK, Jansen D, Juza RM, Kersten M, Olson K, Hendricks B, (2006). Benefit of adding pioglitazone to statin therapy in non-diabetic patients with the metabolic syndrome. WMJ 105: 22-25. (Pubitemid 44222724)
-
(2006)
Wisconsin Medical Journal
, vol.105
, Issue.5
, pp. 22-25
-
-
Murdock, D.K.1
Jansen, D.2
Juza, R.M.3
Kersten, M.4
Olson, K.5
Hendricks, B.6
-
35
-
-
34250212715
-
Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes
-
Nissen SE, Wolski K, (2007). Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. N Engl J Med 356: 2457-2471. (Pubitemid 46919772)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.24
, pp. 2457-2471
-
-
Nissen, S.E.1
Wolski, K.2
-
36
-
-
0036670222
-
Stimulation of peroxisome-proliferator-activated receptor α (PPARα) attenuates cardiac fibrosis and endothelin-1 production in pressure-overloaded rat hearts
-
Ogata T, Miyauchi T, Sakai S, Irukayama-Tomobe Y, Goto K, Yamaguchi I, (2002). Stimulation of peroxisome-proliferator-activated receptor alpha (PPAR alpha) attenuates cardiac fibrosis and endothelin-1 production in pressure overloaded rat hearts. Clin Sci 103: 284S-288S. (Pubitemid 35007171)
-
(2002)
Clinical Science
, vol.103
, Issue.SUPPL. 48
-
-
Ogata, T.1
Miyauchi, T.2
Sakai, S.3
Irukayama-Tomobe, Y.4
Goto, K.5
Yamaguchi, I.6
-
37
-
-
1942484870
-
Myocardial fibrosis and diastolic dysfunction in deoxycorticosterone acetate-salt hypertensive rats is ameliorated by the peroxisome proliferator-activated receptor-alpha activator fenofibrate, partly by suppressing inflammatory responses associated with the nuclear factor-kappa-B pathway
-
DOI 10.1016/j.jacc.2003.11.043, PII S0735109704001901
-
Ogata T, Miyauchi T, Sakai S, Takanashi M, Irukayama-Tomobe Y, Yamaguchi I, (2004). Myocardial fibrosis and diastolic dysfunction in deoxycorticosterone acetate salt hypertensive rats is ameliorated by the peroxisome proliferator-activated receptor-alpha activator fenofibrate, partly by suppressing inflammatory responses associated with the nuclear factor-kappa-B pathway. J Am Coll Cardiol 43: 1481-1488. (Pubitemid 38496358)
-
(2004)
Journal of the American College of Cardiology
, vol.43
, Issue.8
, pp. 1481-1488
-
-
Ogata, T.1
Miyauchi, T.2
Sakai, S.3
Takanashi, M.4
Irukayama-Tomobe, Y.5
Yamaguchi, I.6
-
38
-
-
0037432192
-
Effect of classic preconditioning on the gene expression pattern of rat hearts: A DNA microarray study
-
DOI 10.1016/S0014-5793(03)00006-1
-
Onody A, Zvara A, Hackler L Jr, Vígh L, Ferdinandy P, Puskás LG, (2003). Effect of classic preconditioning on the gene expression pattern of rat hearts: a DNA microarray study. FEBS Lett 536: 35-40. (Pubitemid 36206402)
-
(2003)
FEBS Letters
, vol.536
, Issue.1-3
, pp. 35-40
-
-
Onody, A.1
Zvara, A.2
Hackler Jr., L.3
Vigh, L.4
Ferdinandy, P.5
Puskas, L.G.6
-
39
-
-
33646817773
-
Acute antiinflammatory properties of statins involve peroxisome proliferators-activated receptor-alpha via inhibition of the protein kinase C signaling pathway
-
Paumelle R, Blanquart C, Briand O, Barbier O, Duhem C, Woerly G, et al,. (2006). Acute antiinflammatory properties of statins involve peroxisome proliferators-activated receptor-alpha via inhibition of the protein kinase C signaling pathway. Circ Res 98: 361-369.
-
(2006)
Circ Res
, vol.98
, pp. 361-369
-
-
Paumelle, R.1
Blanquart, C.2
Briand, O.3
Barbier, O.4
Duhem, C.5
Woerly, G.6
-
40
-
-
77957726317
-
Simvastatin inhibited cardiac hypertrophy and fibrosis in apolipoprotein E-deficient mice fed a 'Western-style diet' by increasing PPAR α and γ expression and reducing TC, MMP-9, and Cat S levels
-
Qin YW, Ye P, He JQ, Sheng L, Wang LY, Du J, (2010). Simvastatin inhibited cardiac hypertrophy and fibrosis in apolipoprotein E-deficient mice fed a 'Western-style diet' by increasing PPAR α and γ expression and reducing TC, MMP-9, and Cat S levels. Acta Pharmacol Sin 31: 1350-1358.
-
(2010)
Acta Pharmacol Sin
, vol.31
, pp. 1350-1358
-
-
Qin, Y.W.1
Ye, P.2
He, J.Q.3
Sheng, L.4
Wang, L.Y.5
Du, J.6
-
41
-
-
76549098871
-
Changes in PPAR gene expression and myocardial tolerance to ischaemia: Relevance to pleiotropic effects of statins
-
Ravingerová T, Adameová A, Kelly T, Antonopoulou E, Pancza D, Ondrejcáková M, et al,. (2009). Changes in PPAR gene expression and myocardial tolerance to ischaemia: relevance to pleiotropic effects of statins. Can J Physiol Pharmacol 87: 1028-1036.
-
(2009)
Can J Physiol Pharmacol
, vol.87
, pp. 1028-1036
-
-
Ravingerová, T.1
Adameová, A.2
Kelly, T.3
Antonopoulou, E.4
Pancza, D.5
Ondrejcáková, M.6
-
42
-
-
79955915448
-
PPARα mediates the anti-inflammatory effect of simvastatin in an experimental model of zymosan-induced multiple organ failure
-
Rinaldi B, Donniacuo M, Esposito E, Capuano A, Sodano L, Mazzon E, et al,. (2011). PPARα mediates the anti-inflammatory effect of simvastatin in an experimental model of zymosan-induced multiple organ failure. Br J Pharmacol 163: 609-623.
-
(2011)
Br J Pharmacol
, vol.163
, pp. 609-623
-
-
Rinaldi, B.1
Donniacuo, M.2
Esposito, E.3
Capuano, A.4
Sodano, L.5
Mazzon, E.6
-
43
-
-
0036082627
-
Atorvastatin treatment induced peroxisome proliferator-activated receptor α expression and decreased plasma nonesterified fatty acids and liver triglyceride in fructose-fed rats
-
DOI 10.1124/jpet.302.1.232
-
Roglans N, Sanguino E, Peris C, Alegret M, Vázquez M, Adzet T, et al,. (2002). Atorvastatin treatment induced peroxisome proliferator-activated receptor alpha expression and decreased plasma nonesterified fatty acids and liver triglyceride in fructose-fed rats. J Pharmacol Exp Ther 302: 232-239. (Pubitemid 34680443)
-
(2002)
Journal of Pharmacology and Experimental Therapeutics
, vol.302
, Issue.1
, pp. 232-239
-
-
Roglans, N.1
Sanguino, E.2
Peris, C.3
Alegret, M.4
Vazquez, M.5
Adzet, T.6
Diaz, C.7
Hernandez, G.8
Laguna, J.C.9
Sanchez, R.M.10
-
44
-
-
23044464574
-
Atorvastatin reverses age-related reduction in rat hepatic PPARα and HNF-4
-
DOI 10.1038/sj.bjp.0706260
-
Sanguino E, Roglans N, Alegret M, Sánchez RM, Vázquez- Carrera M, Laguna JC, (2005). Atorvastatin reverses age-related reduction in rat hepatic PPARalpha and HNF-4. Br J Pharmacol 145: 853-861. (Pubitemid 41129006)
-
(2005)
British Journal of Pharmacology
, vol.145
, Issue.7
, pp. 853-861
-
-
Sanguino, E.1
Roglans, N.2
Alegret, M.3
Sanchez, R.M.4
Vazquez-Carrera, M.5
Laguna, J.C.6
-
45
-
-
77958529709
-
Cardiovascular risk and thiazolidinediones-what do meta-analyses really tell us?
-
Schernthaner G, Chilton RJ, (2010). Cardiovascular risk and thiazolidinediones-what do meta-analyses really tell us? Diabetes Obes Metab 12: 1023-1035.
-
(2010)
Diabetes Obes Metab
, vol.12
, pp. 1023-1035
-
-
Schernthaner, G.1
Chilton, R.J.2
-
46
-
-
78049243976
-
Simvastatin attenuates cardiopulmonary bypass-induced myocardial inflammatory injury in rats by activating peroxisome proliferator-activated receptor γ
-
Shen Y, Wu H, Wang C, Shao H, Huang H, Jing H, et al,. (2010). Simvastatin attenuates cardiopulmonary bypass-induced myocardial inflammatory injury in rats by activating peroxisome proliferator-activated receptor γ. Eur J Pharmacol 649: 255-262.
-
(2010)
Eur J Pharmacol
, vol.649
, pp. 255-262
-
-
Shen, Y.1
Wu, H.2
Wang, C.3
Shao, H.4
Huang, H.5
Jing, H.6
-
47
-
-
73349123205
-
Atorvastatin upregulates the expression of PPAR alpha/gamma and inhibits the hypertrophy of cardiac myocytes in vitro
-
Sheng L, Ye P, Liu YX, (2005). Atorvastatin upregulates the expression of PPAR alpha/gamma and inhibits the hypertrophy of cardiac myocytes in vitro. Zhonghua Xin Xue Guan Bing Za Zhi 33: 1080-1084.
-
(2005)
Zhonghua Xin Xue Guan Bing Za Zhi
, vol.33
, pp. 1080-1084
-
-
Sheng, L.1
Ye, P.2
Liu, Y.X.3
-
48
-
-
46849111226
-
Benefit of adding Pioglitazone to successful statin therapy in nondiabetic patients with coronary artery disease
-
DOI 10.1253/circj.72.1193
-
Sugamura K, Sugiyama S, Matsuzawa Y, Nozaki T, Horibata Y, Ogawa H, (2008). Benefit of adding pioglitazone to successful statin therapy in nondiabetic patients with coronary artery disease. Circ J 72: 1193-1197. (Pubitemid 351957091)
-
(2008)
Circulation Journal
, vol.72
, Issue.7
, pp. 1193-1197
-
-
Sugamura, K.1
Sugiyama, S.2
Matsuzawa, Y.3
Nozaki, T.4
Horibata, Y.5
Ogawa, H.6
-
49
-
-
34547774295
-
The dual peroxisome proliferator-activated receptor α/γ agonist tesaglitazar further improves the lipid profile in dyslipidemic subjects treated with atorvastatin
-
DOI 10.1016/j.metabol.2007.05.003, PII S0026049507001849
-
Tonstad S, Retterstàl K, Ose L, Ohman KP, Lindberg MB, Svensson M, (2007). The dual peroxisome proliferator-activated receptor alpha/gamma agonist tesaglitazar further improves the lipid profile in dyslipidemic subjects treated with atorvastatin. Metabolism 56: 1285-1292. (Pubitemid 47241145)
-
(2007)
Metabolism: Clinical and Experimental
, vol.56
, Issue.9
, pp. 1285-1292
-
-
Tonstad, S.1
Retterstol, K.2
Ose, L.3
Ohman, K.P.4
Lindberg, M.B.5
Svensson, M.6
-
50
-
-
0028910272
-
Beneficial effects of cholesterol-lowering therapy on the coronary endothelium in patients with coronary artery disease
-
Treasure CB, Klein JL, Weintraub WS, Talley JD, Stillabower ME, Kosinski AS, et al,. (1995). Beneficial effects of cholesterol-lowering therapy on the coronary endothelium in patients with coronary artery disease. N Engl J Med 332: 481-487.
-
(1995)
N Engl J Med
, vol.332
, pp. 481-487
-
-
Treasure, C.B.1
Klein, J.L.2
Weintraub, W.S.3
Talley, J.D.4
Stillabower, M.E.5
Kosinski, A.S.6
-
51
-
-
71349086893
-
Rhabdomyolysis associated with fibrate therapy: Review of 76 published cases and a new case report
-
Wu J, Song Y, Li H, Chen J, (2009). Rhabdomyolysis associated with fibrate therapy: review of 76 published cases and a new case report. Eur J Clin Pharmacol 65: 1169-1174.
-
(2009)
Eur J Clin Pharmacol
, vol.65
, pp. 1169-1174
-
-
Wu, J.1
Song, Y.2
Li, H.3
Chen, J.4
-
52
-
-
79251472161
-
Effects of atorvastatin and losartan on monocrotaline-induced pulmonary artery remodeling in rats
-
Xie L, Lin P, Xie H, Xu C, (2010). Effects of atorvastatin and losartan on monocrotaline-induced pulmonary artery remodeling in rats. Clin Exp Hypertens 32: 547-554.
-
(2010)
Clin Exp Hypertens
, vol.32
, pp. 547-554
-
-
Xie, L.1
Lin, P.2
Xie, H.3
Xu, C.4
-
53
-
-
34249723258
-
Statins activate peroxisome proliferator-activated receptor γ through extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase-dependent cyclooxygenase-2 expression in macrophages
-
DOI 10.1161/01.RES.0000268411.49545.9c
-
Yano M, Matsumura T, Senokuchi T, Ishii N, Murata Y, Taketa K, et al,. (2007). Statins activate peroxisome proliferators-activated receptor gamma through extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase-dependent cyclooxygenase-2 expression in macrophages. Circ Res 100: 1442-1451. (Pubitemid 46834756)
-
(2007)
Circulation Research
, vol.100
, Issue.10
, pp. 1442-1451
-
-
Yano, M.1
Matsumura, T.2
Senokuchi, T.3
Ishii, N.4
Murata, Y.5
Taketa, K.6
Motoshima, H.7
Taguchi, T.8
Sonoda, K.9
Kukidome, D.10
Takuwa, Y.11
Kawada, T.12
Brownlee, M.13
Nishikawa, T.14
Araki, E.15
-
54
-
-
33947512398
-
Atorvastatin attenuating down-regulation of peroxisome proliferator-activated receptor gamma in preventing cardiac hypertrophy of rats in vitro and in vivo
-
Ye P, Sheng L, Zhang C, Liu Y, (2006). Atorvastatin attenuating down-regulation of peroxisome proliferator-activated receptor gamma in preventing cardiac hypertrophy of rats in vitro and in vivo. J Pharm Pharm Sci 9: 365-375. (Pubitemid 46629864)
-
(2006)
Journal of Pharmacy and Pharmaceutical Sciences
, vol.9
, Issue.3
, pp. 365-375
-
-
Ye, P.1
Sheng, L.2
Zhang, C.3
Liu, Y.4
-
55
-
-
35548979848
-
The role of fenofibrate in clinical practice
-
DOI 10.3132/dvdr.2007.053
-
Zambon A, Cusi K, (2007). The role of fenofibrate in clinical practice. Diab Vasc Dis Res 4: S15-S20. (Pubitemid 350013473)
-
(2007)
Diabetes and Vascular Disease Research
, vol.4
, Issue.SUPPL. 3
-
-
Zambon, A.1
Cusi, K.2
-
56
-
-
0036445650
-
Modulation of inflammatory mediators and PPARγ and NFB expression by pravastatin in response to lipoproteins in human monocytes in vitro
-
DOI 10.1006/phrs.2001.0922
-
Zelvyte I, Dominaitiene R, Crisby M, Janciauskiene S, (2002). Modulation of inflammatory mediators and PPARgamma and NFkappaB expression by pravastatin in response to lipoproteins in human monocytes in vitro. Pharmacol Res 45: 147-154. (Pubitemid 35425654)
-
(2002)
Pharmacological Research
, vol.45
, Issue.2
, pp. 147-154
-
-
Zelvyte, I.1
Dominaitiene, R.2
Crisby, M.3
Janciauskiene, S.4
|