Probing the intestinal α-glucosidase enzyme specificities of starch-digesting maltase-glucoamylase and sucrase-isomaltase: Synthesis and inhibitory properties of 3′- and 5′-maltose-extended De-O-sulfonated ponkoranol

Chemistry - A European Journal

Volumn 17, Issue 52, 2011, Pages 14817-14825

  Eskandari, Razieh ^a   Jones, Kyra ^b   Ravinder Reddy, Kongara ^a   Jayakanthan, Kumarasamy ^a   Chaudet, Marcia ^b   Rose, David R ^b   Pinto, B Mario ^a  

^a SIMON FRASER UNIVERSITY   (Canada)

^b UNIVERSITY OF WATERLOO   (Canada)

Author keywords

enzyme catalysis; inhibitors; intestinal glucosidases; maltose extended de O sulfonated ponkoranol; sulfonium ions

Indexed keywords

ALKYLATING AGENTS; D-GLUCOSE; DEPROTECTION; ENZYME CATALYSIS; ENZYME SPECIFICITY; GLUCOSIDASE; GLUCOSIDASE ACTIVITY; GLYCOSIDE HYDROLASE FAMILY 31; INHIBITORY ACTIVITY; INTESTINAL GLUCOSIDASES; MALTOSE-EXTENDED-DE-O- SULFONATED PONKORANOL; NATURALLY OCCURRING; NUCLEOPHILIC ATTACK; SELECTIVE INHIBITION; STARCH PRODUCTS; SULFONIUM IONS; TARGET COMPOUND;

CORROSION INHIBITORS; ENZYME ACTIVITY; GLUCOSE; IONS; MALTOSE; MUTAGENS; STARCH;

ENZYME INHIBITION;

ALPHA GLUCOSIDASE; ENZYME INHIBITOR; MALTOSE; PONKORANOL; STARCH; SUCRASE ISOMALTASE; SULFONIUM DERIVATIVE; THIOPHENE DERIVATIVE;

ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; ENZYMOLOGY; HUMAN; INTESTINE; METABOLISM; STEREOISOMERISM; SYNTHESIS;

ALPHA-GLUCOSIDASES; CATALYSIS; ENZYME INHIBITORS; HUMANS; INTESTINES; MALTOSE; MOLECULAR STRUCTURE; STARCH; STEREOISOMERISM; SUCRASE-ISOMALTASE COMPLEX; SULFONIUM COMPOUNDS; THIOPHENES;

EID: 83755219909     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.201102109     Document Type: Article

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