Synthesis and antitumor activity of new shikonin glycosides

European Journal of Medicinal Chemistry

Volumn 45, Issue 7, 2010, Pages 2713-2718

  Su, Yehua ^a   Xie, Jiansheng ^b   Wang, Yanguang ^a   Hu, Xun ^b   Lin, Xianfu ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Antitumor; Drug resistance; Glycosides; Shikonin; Synthesis

Indexed keywords

1 (1 (5,8 DIHYDROXY 1,4 NAPHTHOQUINONE 2 YL) 4 METHYL 3 PENTENYLOXY) 2,3,4 TRI O ACETYL BETA DEXTRO ARABO FURANOSIDE; 1 (1 (5,8 DIHYDROXY 1,4 NAPHTHOQUINONE 2 YL) 4 METHYL 3 PENTENYLOXY) 2,3,4 TRI O ACETYL BETA DEXTRO RIBOFURANOSIDE; 1 (1 (5,8 DIHYDROXY 1,4 NAPHTHOQUINONE 2 YL) 4 METHYL 3 PENTENYLOXY) 2,3,4 TRI O ACETYL BETA LEVO ARABOFURANOSIDE; 1 (1 (5,8 DIHYDROXY 1,4 NAPHTHOQUINONE 2 YL) 4 METHYL 3 PENTENYLOXY) 2,3,4 TRI O ACETYL BETA RHAMPYRANOSIDE; 1 (1 (5,8 DIHYDROXY 1,4 NAPHTHOQUINONE 2 YL) 4 METHYL 3 PENTENYLOXY) 2,3,4 TRI O ACETYL BETA XYLOPYRANOSIDE; 1 (1 (5,8 DIHYDROXY 1,4 NAPHTHOQUINONE 2 YL) 4 METHYL 3 PENTENYLOXY) 2,3,4,6 TETRA O ACETYL BETA GALACTO PYRANOSIDE; 1 (1 (5,8 DIHYDROXY 1,4 NAPHTHOQUINONE 2 YL) 4 METHYL 3 PENTENYLOXY) 2,3,4,6 TETRA O ACETYL BETA GLUCOPYRANOSIDE; 1 (1 (5,8 DIHYDROXY 1,4 NAPHTHOQUINONE 2 YL) 4 METHYL 3 PENTENYLOXY) 2,3,4,6 TETRA O ACETYL BETA MANNO PYRANOSIDE; 1 (1 (5,8 DIHYDROXY 1,4 NAPHTHOQUINONE 2 YL) 4 METHYL 3 PENTENYLOXY) 2,3,6,2',3',4',6' HEPTA O ACETYL BETA CELLUBIOSIDE; 1 (1 (5,8 DIHYDROXY 1,4 NAPHTHOQUINONE 2 YL) 4 METHYL 3 PENTENYLOXY) 2,3,6,2',3',4',6' HEPTA O ACETYL BETA LACTOSIDE; 1 (1 (5,8 DIHYDROXY 1,4 NAPHTHOQUINONE 2 YL) 4 METHYL 3 PENTENYLOXY) 2,3,6,2',3',4',6' HEPTA O ACETYL BETA MALTOSIDE; AMINOSUGAR; ANTINEOPLASTIC AGENT; GLYCOPROTEIN P; GLYCOSIDE; HYDRAZINE DERIVATIVE; MULTIDRUG RESISTANCE PROTEIN 1; SHIKONIN DERIVATIVE; SUGAR; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER RESISTANCE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL PROLIFERATION; CELL STRAIN HL 60; CELL STRAIN K 562; CELL STRAIN MCF 7; CHEMICAL REACTION; CHEMICAL STRUCTURE; CYTOTOXICITY; DRUG ACETYLATION; DRUG SYNTHESIS; GLYCOSYLATION; IC 50; IN VITRO STUDY; INFRARED SPECTROSCOPY; MULTIDRUG RESISTANCE; NONHUMAN; PHARMACOPHORE; PROTON NUCLEAR MAGNETIC RESONANCE;

ANTINEOPLASTIC AGENTS; GLYCOSIDES; HUMANS; INHIBITORY CONCENTRATION 50; NAPHTHOQUINONES;

EID: 77954348864     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2010.02.002     Document Type: Article

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