TLR3 signaling is either protective or pathogenic for the development of Theiler's virus-induced demyelinating disease depending on the time of viral infection

Journal of Neuroinflammation

Volumn 8, Issue , 2011, Pages

  Jin, Young Hee ^a   Kaneyama, Tomoki ^b   Kang, Min H ^a   Kang, Hyun S ^a   Koh, Chang Sung ^b   Kim, Byung S ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b SHINSHU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

CNS; Demyelination; T cell responses; TLR3; TMEV

Indexed keywords

CD11B ANTIGEN; GAMMA INTERFERON; POLYINOSINIC POLYCYTIDYLIC ACID; TOLL LIKE RECEPTOR 3; TRANSCRIPTION FACTOR FOXP3; TLR3 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL INFILTRATION; CELL ISOLATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DEMYELINATING DISEASE; ENCEPHALITIS; FLOW CYTOMETRY; HISTOPATHOLOGY; IMMUNE RESPONSE; MOUSE; MURINE ENCEPHALOMYELITIS VIRUS; NONHUMAN; PATHOGENESIS; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE SUBPOPULATION; VIRUS INFECTION; VIRUS LOAD; VIRUS STRAIN; ANIMAL; CARDIOVIRUS INFECTION; IMMUNOLOGY; METABOLISM; MOUSE MUTANT; VIROLOGY;

ANIMALS; CARDIOVIRUS INFECTIONS; DEMYELINATING DISEASES; FLOW CYTOMETRY; MICE; MICE, KNOCKOUT; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; THEILOVIRUS; TOLL-LIKE RECEPTOR 3;

EID: 83755187877     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/1742-2094-8-178     Document Type: Article

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