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Volumn 8, Issue 1, 2012, Pages 99-112

Integrating breast cancer genetics into clinical practice

Author keywords

breast cancer; genetics; genomics; management; outcome

Indexed keywords

ANTHRACYCLINE; ANTHRACYCLINE DERIVATIVE; BEVACIZUMAB; CARBOPLATIN; CISPLATIN; DASATINIB; EVEROLIMUS; GEFITINIB; LAPATINIB; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; RIDAFOROLIMUS; TAMOXIFEN; TAXANE DERIVATIVE; TEMSIROLIMUS; TRASTUZUMAB; TYKREB; UNCLASSIFIED DRUG;

EID: 83755180433     PISSN: 17455057     EISSN: 17455065     Source Type: Journal    
DOI: 10.2217/whe.11.81     Document Type: Review
Times cited : (4)

References (106)
  • 2
    • 0029248011 scopus 로고
    • Induction of apoptosis by tumor suppressor genes and oncogenes
    • Canman CE, Kastan MB. Induction of apoptosis by tumor suppressor genes and oncogenes. Semin. Cancer Biol. 6(1), 17-25 (1995).
    • (1995) Semin. Cancer Biol. , vol.6 , Issue.1 , pp. 17-25
    • Canman, C.E.1    Kastan, M.B.2
  • 3
    • 0035695542 scopus 로고    scopus 로고
    • The challenge of pathway and environment-mediated drug resistance
    • DOI 10.1023/A:1013127605407
    • Sausville EA. The challenge of pathway and environment-mediated drug resistance. Cancer Metastasis Rev. 20(1-2), 117-122 (2001). (Pubitemid 34074687)
    • (2001) Cancer and Metastasis Reviews , vol.20 , Issue.1-2 , pp. 117-122
    • Sausville, E.A.1
  • 4
    • 34250887474 scopus 로고    scopus 로고
    • Taking gene-expression profiling to the clinic: When will molecular signatures become relevant to patient care?
    • DOI 10.1038/nrc2173, PII NRC2173
    • Sotiriou C, Piccart MJ. Taking gene-expression profiling to the clinic: when will molecular signatures become relevant to patient care? Nat. Rev. Cancer 7(7), 545-553 (2007). (Pubitemid 46985399)
    • (2007) Nature Reviews Cancer , vol.7 , Issue.7 , pp. 545-553
    • Sotiriou, C.1    Piccart, M.J.2
  • 5
    • 33645750432 scopus 로고    scopus 로고
    • DNA testing genetic screen misses mutations in women at high risk of breast cancer
    • Stokstad E. DNA testing. Genetic screen misses mutations in women at high risk of breast cancer. Science 311(5769), 1847 (2006).
    • (2006) Science , vol.311 , Issue.5769 , pp. 1847
    • Stokstad, E.1
  • 6
    • 13844250828 scopus 로고    scopus 로고
    • Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors
    • USA
    • Pollack JR, Sorlie T, Perou CM et al. Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors. Proc. Natl Acad. Sci. USA 99(20), 12963-12968 (2002).
    • (2002) Proc. Natl Acad. Sci. , vol.99 , Issue.20 , pp. 12963-12968
    • Pollack, J.R.1    Sorlie, T.2    Perou, C.M.3
  • 7
    • 79957846432 scopus 로고    scopus 로고
    • The molecular subtype classification is a determinant of sentinel node positivity in early breast carcinoma
    • Reyal F, Rouzier R, Depont-Hazelzet B et al. The molecular subtype classification is a determinant of sentinel node positivity in early breast carcinoma. PLoS One 6(5), e20297 (2011).
    • (2011) PLoS One , vol.6 , Issue.5
    • Reyal, F.1    Rouzier, R.2    Depont-Hazelzet, B.3
  • 8
    • 78649992702 scopus 로고    scopus 로고
    • Breast cancer prognostic classification in the molecular era: The role of histological grade
    • Rakha EA, Reis-Filho JS, Baehner F et al. Breast cancer prognostic classification in the molecular era: the role of histological grade. Breast Cancer Res. 12(4), 207 (2010).
    • (2010) Breast Cancer Res. , vol.12 , Issue.4 , pp. 207
    • Rakha, E.A.1    Reis-Filho, J.S.2    Baehner, F.3
  • 11
    • 41649114164 scopus 로고    scopus 로고
    • Enabling personalized cancer medicine through analysis of gene-expression patterns
    • DOI 10.1038/nature06915, PII NATURE06915
    • Van't Veer LJ, Bernards R. Enabling personalized cancer medicine through analysis of gene-expression patterns. Nature 452(7187), 564-570 (2008). (Pubitemid 351483370)
    • (2008) Nature , vol.452 , Issue.7187 , pp. 564-570
    • Van 't Veer, L.J.1    Bernards, R.2
  • 13
    • 0034680102 scopus 로고    scopus 로고
    • Molecular portraits of human breast tumors
    • Perou CM, Sorlie T, Eisen MB et al. Molecular portraits of human breast tumors. Nature 406(6797), 747-752 (2000).
    • (2000) Nature , vol.406 , Issue.6797 , pp. 747-752
    • Perou, C.M.1    Sorlie, T.2    Eisen, M.B.3
  • 19
    • 58149330982 scopus 로고    scopus 로고
    • Meta-analysis of gene expression profiles in breast cancer: Toward a unified understanding of breast cancer subtyping and prognosis signatures
    • Wirapati P, Sotiriou C, Kunkel S et al. Meta-analysis of gene expression profiles in breast cancer: toward a unified understanding of breast cancer subtyping and prognosis signatures. Breast Cancer Res. 10(4), R65 (2008).
    • (2008) Breast Cancer Res. , vol.10 , Issue.4
    • Wirapati, P.1    Sotiriou, C.2    Kunkel, S.3
  • 21
    • 77951637777 scopus 로고    scopus 로고
    • Prediction of risk of distant recurrence using the 21-gene recurrence score in node-negative and node-positive postmenopausal patients with breast cancer treated with anastrozole or tamoxifen: A TransATAC study
    • Dowsett M, Cuzick J, Wale C et al. Prediction of risk of distant recurrence using the 21-gene recurrence score in node-negative and node-positive postmenopausal patients with breast cancer treated with anastrozole or tamoxifen: a TransATAC study. J. Clin. Oncol. 28(11), 1829-1834 (2010).
    • (2010) J. Clin. Oncol. , vol.28 , Issue.11 , pp. 1829-1834
    • Dowsett, M.1    Cuzick, J.2    Wale, C.3
  • 22
    • 33846051527 scopus 로고    scopus 로고
    • Protein microarray technology
    • DOI 10.1016/j.mad.2006.11.021, PII S0047637406002545, Functional Genomics of Aging III
    • Hall DA, Ptacek J, Snyder M. Protein microarray technology. Mech. Ageing Dev. 128(1), 161-167 (2007). (Pubitemid 46073070)
    • (2007) Mechanisms of Ageing and Development , vol.128 , Issue.1 , pp. 161-167
    • Hall, D.A.1    Ptacek, J.2    Snyder, M.3
  • 23
    • 22244449596 scopus 로고    scopus 로고
    • High-throughput protein expression analysis using tissue microarray technology of a large well-characterised series identifies biologically distinct classes of breast cancer confirming recent cDNA expression analyses
    • DOI 10.1002/ijc.21004
    • Abd El-Rehim DM, Ball G, Pinder SE et al. High-throughput protein expression analysis using tissue microarray technology of a large well-characterized series identifies biologically distinct classes of breast cancer confirming recent cDNA expression analyses. Int. J. Cancer 116(3), 340-350 (2005). (Pubitemid 40993329)
    • (2005) International Journal of Cancer , vol.116 , Issue.3 , pp. 340-350
    • Abd El-Rehim, D.M.1    Ball, G.2    Finder, S.E.3    Rakha, E.4    Paish, C.5    Robertson, J.F.R.6    Macmillan, D.7    Blamey, R.W.8    Ellis, I.O.9
  • 24
    • 60849097255 scopus 로고    scopus 로고
    • Gene-expression signatures in breast cancer
    • Sotiriou C, Pusztai L. Gene-expression signatures in breast cancer. N. Engl. J. Med. 360(8), 790-800 (2009).
    • (2009) N. Engl. J. Med. , vol.360 , Issue.8 , pp. 790-800
    • Sotiriou, C.1    Pusztai, L.2
  • 25
    • 45149094267 scopus 로고    scopus 로고
    • Basal-like breast cancer: A critical review
    • Rakha EA, Reis-Filho JS, Ellis IO. Basal-like breast cancer: a critical review. J. Clin. Oncol. 26(15), 2568-2581 (2008).
    • (2008) J. Clin. Oncol. , vol.26 , Issue.15 , pp. 2568-2581
    • Rakha, E.A.1    Reis-Filho, J.S.2    Ellis, I.O.3
  • 27
    • 33747819585 scopus 로고    scopus 로고
    • Clinicopathologic significance of the basal-like subtype of breast cancer: A comparison with hormone receptor and Her2/neu-overexpressing phenotypes
    • DOI 10.1016/j.humpath.2006.04.015, PII S0046817706002644
    • Kim MJ, Ro JY, Ahn SH, Kim HH, Kim SB, Gong G. Clinicopathologic significance of the basal-like subtype of breast cancer: a comparison with hormone receptor and HER2/neu-overexpressing phenotypes. Hum. Pathol. 37(9), 1217-1226 (2006). (Pubitemid 44286991)
    • (2006) Human Pathology , vol.37 , Issue.9 , pp. 1217-1226
    • Kim, M.-J.1    Ro, J.Y.2    Ahn, S.-H.3    Kim, H.H.4    Kim, S.-B.5    Gong, G.6
  • 29
    • 81155133281 scopus 로고    scopus 로고
    • Prognostic value of a combined estrogen receptor progesterone receptor Ki-67 and human epidermal growth factor receptor 2 immunohistochemical score and comparison with the genomic health recurrence score in early breast cancer
    • Cuzick J, Dowsett M, Pineda S et al. Prognostic value of a combined estrogen receptor, progesterone receptor, Ki-67, and human epidermal growth factor receptor 2 immunohistochemical score and comparison with the genomic health recurrence score in early breast cancer. J. Clin. Oncol. 29(32), 4273-4278 (2011).
    • (2011) J. Clin. Oncol. , vol.29 , Issue.32 , pp. 4273-4278
    • Cuzick, J.1    Dowsett, M.2    Pineda, S.3
  • 31
    • 78449291165 scopus 로고    scopus 로고
    • Utility of oncotype DX risk estimates in clinically intermediate risk hormone receptor-positive HER2-normal grade II lymph node-negative breast cancers
    • Kelly CM, Krishnamurthy S, Bianchini G et al. Utility of oncotype DX risk estimates in clinically intermediate risk hormone receptor-positive, HER2-normal, grade II, lymph node-negative breast cancers. Cancer 116(22), 5161-5167 (2010).
    • (2010) Cancer , vol.116 , Issue.22 , pp. 5161-5167
    • Kelly, C.M.1    Krishnamurthy, S.2    Bianchini, G.3
  • 33
    • 33646255471 scopus 로고    scopus 로고
    • A two-gene expression ratio of homeobox 13 and interleukin 17B receptor for prediction of recurrence and survival in women receiving adjuvant tamoxifen
    • 7 Pt 1
    • Goetz MP, Suman VJ, Ingle JN et al. A two-gene expression ratio of homeobox 13 and interleukin 17B receptor for prediction of recurrence and survival in women receiving adjuvant tamoxifen. Clin. Cancer Res. 12(7 Pt 1), 2080-2087 (2006)
    • (2006) Clin. Cancer Res. , vol.12 , pp. 2080-2087
    • Goetz, M.P.1    Suman, V.J.2    Ingle, J.N.3
  • 38
    • 33644551073 scopus 로고    scopus 로고
    • Gene expression programs in response to hypoxia: Cell type specificity and prognostic significance in human cancers
    • Chi JT, Wang Z, Nuyten DS et al. Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers. PLoS Med. 3(3), e47 (2006).
    • (2006) PLoS Med. , vol.3 , Issue.3
    • Chi, J.T.1    Wang, Z.2    Nuyten, D.S.3
  • 39
    • 0034782631 scopus 로고    scopus 로고
    • Molecular classification of breast cancer patients by gene expression profiling
    • Ahr A, Holtrich U, Solbach C et al. Molecular classification of breast cancer patients by gene expression profiling. J. Pathol. 195(3), 312-320 (2001).
    • (2001) J. Pathol. , vol.195 , Issue.3 , pp. 312-320
    • Ahr, A.1    Holtrich, U.2    Solbach, C.3
  • 40
    • 79960841940 scopus 로고    scopus 로고
    • Development of 95-gene classifier as a powerful predictor of recurrences in node-negative and ER-positive breast cancer patients
    • Naoi Y, Kishi K, Tanei T et al. Development of 95-gene classifier as a powerful predictor of recurrences in node-negative and ER-positive breast cancer patients. Breast Cancer Res. Treat. 128(3), 633-641 (2011).
    • (2011) Breast Cancer Res. Treat. , vol.128 , Issue.3 , pp. 633-641
    • Naoi, Y.1    Kishi, K.2    Tanei, T.3
  • 41
    • 79957617088 scopus 로고    scopus 로고
    • Prognostic utility of HOXB13:IL17BR and molecular grade index in early-stage breast cancer patients from the stockholm trial
    • Jerevall PL, Ma XJ, Li H et al. Prognostic utility of HOXB13:IL17BR and molecular grade index in early-stage breast cancer patients from the Stockholm trial. Br. J. Cancer 104(11), 1762-1769 (2011).
    • (2011) Br. J. Cancer , vol.104 , Issue.11 , pp. 1762-1769
    • Jerevall, P.L.1    Ma, X.J.2    Li, H.3
  • 42
    • 33744808550 scopus 로고    scopus 로고
    • A population-based study of tumor gene expression and risk of breast cancer death among lymph node-negative patients
    • Habel LA, Shak S, Jacobs MK et al. A population-based study of tumor gene expression and risk of breast cancer death among lymph node-negative patients. Breast Cancer Res. 8(3), R25 (2006).
    • (2006) Breast Cancer Res. , vol.8 , Issue.3
    • Habel, L.A.1    Shak, S.2    Jacobs, M.K.3
  • 44
    • 52049095087 scopus 로고    scopus 로고
    • A five-gene molecular grade index and HOXB13:IL17BR are complementary prognostic factors in early stage breast cancer
    • Ma XJ, Salunga R, Dahiya S et al. A five-gene molecular grade index and HOXB13:IL17BR are complementary prognostic factors in early stage breast cancer. Clin. Cancer Res. 14(9), 2601-2608 (2008).
    • (2008) Clin. Cancer Res. , vol.14 , Issue.9 , pp. 2601-2608
    • Ma, X.J.1    Salunga, R.2    Dahiya, S.3
  • 45
    • 34648829133 scopus 로고    scopus 로고
    • An immune response gene expression module identifies a good prognosis subtype in estrogen receptor negative breast cancer
    • Teschendorff AE, Miremadi A, Pinder SE, Ellis IO, Caldas C. An immune response gene expression module identifies a good prognosis subtype in estrogen receptor negative breast cancer. Genome Biol. 8(8), R157 (2007).
    • (2007) Genome Biol. , vol.8 , Issue.8
    • Teschendorff, A.E.1    Miremadi, A.2    Pinder, S.E.3    Ellis, I.O.4    Caldas, C.5
  • 46
    • 51349088017 scopus 로고    scopus 로고
    • Biological processes associated with breast cancer clinical outcome depend on the molecular subtypes
    • Desmedt C, Haibe-Kains B, Wirapati P et al. Biological processes associated with breast cancer clinical outcome depend on the molecular subtypes. Clin. Cancer Res. 14(16), 5158-5165 (2008).
    • (2008) Clin. Cancer Res. , vol.14 , Issue.16 , pp. 5158-5165
    • Desmedt, C.1    Haibe-Kains, B.2    Wirapati, P.3
  • 48
    • 79952198073 scopus 로고    scopus 로고
    • A prognostic DNA signature for T1T2 node-negative breast cancer patients
    • Gravier E, Pierron G, Vincent-Salomon A et al. A prognostic DNA signature for T1T2 node-negative breast cancer patients. Genes Chromosomes Cancer 49(12), 1125-1134 (2010).
    • (2010) Genes Chromosomes Cancer , vol.49 , Issue.12 , pp. 1125-1134
    • Gravier, E.1    Pierron, G.2    Vincent-Salomon, A.3
  • 49
    • 78649646316 scopus 로고    scopus 로고
    • Breast cancer assessment tools and optimizing adjuvant therapy
    • Oakman C, Santarpia L, Di Leo A. Breast cancer assessment tools and optimizing adjuvant therapy. Nat. Rev. Clin. Oncol. 7(12), 725-732 (2010).
    • (2010) Nat. Rev. Clin. Oncol. , vol.7 , Issue.12 , pp. 725-732
    • Oakman, C.1    Santarpia, L.2    Di Leo, A.3
  • 50
    • 73249140371 scopus 로고    scopus 로고
    • Prognostic and predictive value of the 21-gene recurrence score assay in postmenopausal women with node-positive oestrogen-receptor-positive breast cancer on chemotherapy: A retrospective analysis of a randomised trial
    • Albain KS, Barlow WE, Shak S et al. Prognostic and predictive value of the 21-gene recurrence score assay in postmenopausal women with node-positive, oestrogen-receptor-positive breast cancer on chemotherapy: a retrospective analysis of a randomised trial. Lancet Oncol. 11(1), 55-65 (2010).
    • (2010) Lancet Oncol. , vol.11 , Issue.1 , pp. 55-65
    • Albain, K.S.1    Barlow, W.E.2    Shak, S.3
  • 53
    • 77954290417 scopus 로고    scopus 로고
    • Clinical significance of the 21-gene signature oncotype DX in hormone receptor-positive early stage primary breast cancer in the Japanese population
    • Toi M, Iwata H, Yamanaka T et al. Clinical significance of the 21-gene signature (Oncotype DX) in hormone receptor-positive early stage primary breast cancer in the Japanese population. Cancer 116(13), 3112-3118 (2010).
    • (2010) Cancer , vol.116 , Issue.13 , pp. 3112-3118
    • Toi, M.1    Iwata, H.2    Yamanaka, T.3
  • 55
    • 83755165084 scopus 로고    scopus 로고
    • BlueCross BlueShield Association BCBSA Technology Evaluation Center TEC Blue Cross and Blue Shield Association Chicago IL USA
    • BlueCross BlueShield Association (BCBSA), Technology Evaluation Center (TEC). Gene Expression Profiling for Managing Breast Cancer Treatment. Blue Cross and Blue Shield Association, Chicago, IL, USA, 22 (2008).
    • (2008) Gene Expression Profiling for Managing Breast Cancer Treatment , vol.22
  • 56
    • 83755184542 scopus 로고    scopus 로고
    • Gene expression profiling of breast cancer to predict the likelihood of recurrence
    • ECRI Institute ECRI Institute PA USA
    • ECRI Institute. Gene Expression Profiling of Breast Cancer to Predict the Likelihood of Recurrence. Emerging technology evidence report. ECRI Institute, PA, USA (2008).
    • (2008) Emerging Technology Evidence Report
  • 57
    • 59849127767 scopus 로고    scopus 로고
    • Recommendations from the EGAPP working group: Can tumor gene expression profiling improve outcomes in patients with breast cancer
    • Evaluation of Genomic Applications in Practice and Prevention EGAPP Working Group
    • Evaluation of Genomic Applications in Practice and Prevention (EGAPP) Working Group. Recommendations from the EGAPP Working Group: can tumor gene expression profiling improve outcomes in patients with breast cancer? Genet. Med. 11(1), 66-73 (2009).
    • (2009) Genet. Med. , vol.11 , Issue.1 , pp. 66-73
  • 58
    • 39149113165 scopus 로고    scopus 로고
    • Development of the 21-gene assay and its application in clinical practice and clinical trials
    • DOI 10.1200/JCO.2007.15.1068
    • Sparano JA, Paik S. Development of the 21-gene assay and its application in clinical practice and clinical trials. J. Clin. Oncol. 26(5), 721-728 (2008). (Pubitemid 351264384)
    • (2008) Journal of Clinical Oncology , vol.26 , Issue.5 , pp. 721-728
    • Sparano, J.A.1    Paik, S.2
  • 63
    • 67650471685 scopus 로고    scopus 로고
    • Inhibition of poly ADP-ribose polymerase in tumors from BRCA mutation carriers
    • Fong PC, Boss DS, Yap TA et al. Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers. N. Engl. J. Med. 361(2), 123-134 (2009).
    • (2009) N. Engl. J. Med. , vol.361 , Issue.2 , pp. 123-134
    • Fong, P.C.1    Boss, D.S.2    Yap, T.A.3
  • 64
    • 54949097426 scopus 로고    scopus 로고
    • Platinum-based chemotherapy in triple-negative breast cancer
    • Sirohi B, Arnedos M, Popat S et al. Platinum-based chemotherapy in triple-negative breast cancer. Ann. Oncol. 19(11), 1847-1852 (2008).
    • (2008) Ann. Oncol. , vol.19 , Issue.11 , pp. 1847-1852
    • Sirohi, B.1    Arnedos, M.2    Popat, S.3
  • 65
    • 67749097987 scopus 로고    scopus 로고
    • Familial breast cancer: Clinical response to induction chemotherapy or radiotherapy related to BRCA1/2 mutations status
    • Fourquet A, Stoppa-Lyonnet D, Kirova YM, Sigal-Zafrani B, Asselain B. Familial breast cancer: clinical response to induction chemotherapy or radiotherapy related to BRCA1/2 mutations status. Am. J. Clin. Oncol. 32(2), 127-131 (2009).
    • (2009) Am. J. Clin. Oncol. , vol.32 , Issue.2 , pp. 127-131
    • Fourquet, A.1    Stoppa-Lyonnet, D.2    Kirova, Y.M.3    Sigal-Zafrani, B.4    Asselain, B.5
  • 68
    • 67649540912 scopus 로고    scopus 로고
    • Basal cytokeratin and epidermal growth factor receptor expression are not predictive of BRCA1 mutation status in women with triple-negative breast cancers
    • Collins LC, Martyniak A, Kandel MJ et al. Basal cytokeratin and epidermal growth factor receptor expression are not predictive of BRCA1 mutation status in women with triple-negative breast cancers. Am. J. Surg. Pathol. 33(7), 1093-1097 (2009).
    • (2009) Am. J. Surg. Pathol. , vol.33 , Issue.7 , pp. 1093-1097
    • Collins, L.C.1    Martyniak, A.2    Kandel, M.J.3
  • 69
    • 77955019276 scopus 로고    scopus 로고
    • Oral poly ADP-ribose polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: A proof-of-concept trial
    • Tutt A, Robson M, Garber JE et al. Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial. Lancet 376(9737), 235-244 (2010).
    • (2010) Lancet , vol.376 , Issue.9737 , pp. 235-244
    • Tutt, A.1    Robson, M.2    Garber, J.E.3
  • 70
    • 79851507487 scopus 로고    scopus 로고
    • Next-generation sequencing: emerging lessons on the origins of human cancer
    • Pfeifer GP, Hainaut P. Next-generation sequencing: emerging lessons on the origins of human cancer. Curr. Opin. Oncol. 23(1), 62-68 (2010).
    • (2010) Curr. Opin. Oncol. , vol.23 , Issue.1 , pp. 62-68
    • Pfeifer, G.P.1    Hainaut, P.2
  • 72
    • 59449085594 scopus 로고    scopus 로고
    • Evidence that molecular changes in cells occur before morphological alterations during the progression of breast ductal carcinoma
    • Castro NP, Osorio CA, Torres C et al. Evidence that molecular changes in cells occur before morphological alterations during the progression of breast ductal carcinoma. Breast Cancer Res. 10(5), R87 (2008).
    • (2008) Breast Cancer Res. , vol.10 , Issue.5
    • Castro, N.P.1    Osorio, C.A.2    Torres, C.3
  • 73
    • 33744940272 scopus 로고    scopus 로고
    • Progression-specific genes identified by expression profiling of matched ductal carcinomas in situ and invasive breast tumors, combining laser capture microdissection and oligonucleotide microarray analysis
    • DOI 10.1158/0008-5472.CAN-05-4610
    • Schuetz CS, Bonin M, Clare SE et al. Progression-specific genes identified by expression profiling of matched ductal carcinomas in situ and invasive breast tumors, combining laser capture microdissection and oligonucleotide microarray analysis. Cancer Res. 66(10), 5278-5286 (2006). (Pubitemid 43844952)
    • (2006) Cancer Research , vol.66 , Issue.10 , pp. 5278-5286
    • Schuetz, C.S.1    Bonin, M.2    Clare, S.E.3    Nieselt, K.4    Sotlar, K.5    Walter, M.6    Fehm, T.7    Solomayer, E.8    Riess, O.9    Wallwiener, D.10    Kurek, R.11    Neubauer, H.J.12
  • 74
    • 0036838070 scopus 로고    scopus 로고
    • Estrogen receptor breast cancer phenotypes in the Surveillance, Epidemiology, and End Results database
    • DOI 10.1023/A:1020299707510
    • Anderson WF, Chatterjee N, Ershler WB, Brawley OW. Estrogen receptor breast cancer phenotypes in the surveillance, epidemiology, and end results database. Breast Cancer Res. Treat. 76(1), 27-36 (2002). (Pubitemid 35178626)
    • (2002) Breast Cancer Research and Treatment , vol.76 , Issue.1 , pp. 27-36
    • Anderson, W.F.1    Chatterjee, N.2    Ershler, W.B.3    Brawley, O.W.4
  • 75
    • 79551604866 scopus 로고    scopus 로고
    • Pharmacogenetics of endocrine therapy for breast cancer
    • Higgins MJ, Stearns V. Pharmacogenetics of endocrine therapy for breast cancer. Ann. Rev. Med. 62, 281-293 (2011).
    • (2011) Ann. Rev. Med. , vol.62 , pp. 281-293
    • Higgins, M.J.1    Stearns, V.2
  • 77
    • 79959735521 scopus 로고    scopus 로고
    • RERG ras-like oestrogen-regulated growth-inhibitor expression in breast cancer: A marker of ER-positive luminal-like subtype
    • Habashy HO, Powe DG, Glaab E et al. RERG (Ras-like, oestrogen-regulated, growth-inhibitor) expression in breast cancer: a marker of ER-positive luminal-like subtype. Breast Cancer Res. Treat. 128(2), 315-326 (2010).
    • (2010) Breast Cancer Res. Treat. , vol.128 , Issue.2 , pp. 315-326
    • Habashy, H.O.1    Powe, D.G.2    Glaab, E.3
  • 78
    • 46049099977 scopus 로고    scopus 로고
    • Forkhead-box A1 FOXA1 expression in breast cancer and its prognostic significance
    • Habashy HO, Powe DG, Rakha EA et al. Forkhead-box A1 (FOXA1) expression in breast cancer and its prognostic significance. Eur. J. Cancer 44(11), 1541-1551 (2008).
    • (2008) Eur. J. Cancer , vol.44 , Issue.11 , pp. 1541-1551
    • Habashy, H.O.1    Powe, D.G.2    Rakha, E.A.3
  • 79
    • 0038575385 scopus 로고    scopus 로고
    • Expression of the HER1-4 family of receptor tyrosine kinases in breast cancer
    • DOI 10.1002/path.1370
    • Witton CJ, Reeves JR, Going JJ, Cooke TG, Bartlett JM. Expression of the HER1-4 family of receptor tyrosine kinases in breast cancer. J. Pathol. 200(3), 290-297 (2003). (Pubitemid 36827302)
    • (2003) Journal of Pathology , vol.200 , Issue.3 , pp. 290-297
    • Witton, C.J.1    Reeves, J.R.2    Going, J.J.3    Cooke, T.G.4    Barlett, J.M.S.5
  • 80
    • 0022406444 scopus 로고
    • Amplification of a novel v-erbB-related gene in a human mammary carcinoma
    • King CR, Kraus MH, Aaronson SA. Amplification of a novel v-erbB-related gene in a human mammary carcinoma. Science 229(4717), 974-976 (1985). (Pubitemid 16248488)
    • (1985) Science , vol.229 , Issue.4717 , pp. 974-976
    • King, C.R.1    Kraus, M.H.2    Aaronson, S.A.3
  • 82
    • 37049183697 scopus 로고
    • Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • Slamon DJ, Clark GM, Wong SG, Levin WJ, Ullrich A, McGuire WL. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 235(4785), 177-182 (1987). (Pubitemid 17231334)
    • (1987) Science , vol.235 , Issue.4785 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3
  • 83
    • 79952840115 scopus 로고    scopus 로고
    • Testing for HER2 in breast cancer: A continuing evolution
    • Shah S, Chen B. Testing for HER2 in breast cancer: a continuing evolution. Patholog. Res. Int. 2011, 903202 (2011).
    • (2011) Patholog. Res. Int. 2011 , pp. 903202
    • Shah, S.1    Chen, B.2
  • 84
    • 34548636864 scopus 로고    scopus 로고
    • Lapatinib: A tyrosine kinase inhibitor with clinical role in breast cancer
    • DOI 10.1517/14656566.8.13.2189
    • Mukherjee A, Dhadda AS, Shehata M, Chan S. Lapatinib: a tyrosine kinase inhibitor with a clinical role in breast cancer. Expert Opin. Pharmacother. 8(13), 2189-2204 (2007). (Pubitemid 47505592)
    • (2007) Expert Opinion on Pharmacotherapy , vol.8 , Issue.13 , pp. 2189-2204
    • Mukherjee, A.1    Dhadda, A.S.2    Shehata, M.3    Chan, S.4
  • 86
    • 79960836840 scopus 로고    scopus 로고
    • Are we missing the mTOR target in breast cancer
    • Johnston SR. Are we missing the mTOR target in breast cancer? Breast Cancer Res. Treat. 128(3), 607-611 (2011).
    • (2011) Breast Cancer Res. Treat. , vol.128 , Issue.3 , pp. 607-611
    • Johnston, S.R.1
  • 87
    • 79960835593 scopus 로고    scopus 로고
    • Overcoming breast cancer drug resistance with mTOR inhibitors could it be a myth or a real possibility in the short-term future
    • Margariti N, Fox SB, Bottini A, Generali D. 'Overcoming breast cancer drug resistance with mTOR inhibitors'. Could it be a myth or a real possibility in the short-term future? Breast Cancer Res. Treat. 128(3), 599-606 (2011).
    • (2011) Breast Cancer Res. Treat. , vol.128 , Issue.3 , pp. 599-606
    • Margariti, N.1    Fox, S.B.2    Bottini, A.3    Generali, D.4
  • 89
    • 1542320044 scopus 로고    scopus 로고
    • Inhibition of HER1 signaling pathway enhances antitumor effect of endocrine therapy in breast cancer
    • Kurebayashi J, Okubo S, Yamamoto Y, Sonoo H. Inhibition of HER1 signaling pathway enhances antitumor effect of endocrine therapy in breast cancer. Breast Cancer 11(1), 38-41 (2004).
    • (2004) Breast Cancer , vol.11 , Issue.1 , pp. 38-41
    • Kurebayashi, J.1    Okubo, S.2    Yamamoto, Y.3    Sonoo, H.4
  • 90
    • 0036164390 scopus 로고    scopus 로고
    • Prognostic value of epidermal growth factor receptor (EGFR) and its relationship to the estrogen receptor status in 1029 patients with breast cancer
    • DOI 10.1023/A:1013397232011
    • Tsutsui S, Ohno S, Murakami S, Hachitanda Y, Oda S. Prognostic value of epidermal growth factor receptor (EGFR) and its relationship to the estrogen receptor status in 1029 patients with breast cancer. Breast Cancer Res. Treat. 71(1), 67-75 (2002). (Pubitemid 34121818)
    • (2002) Breast Cancer Research and Treatment , vol.71 , Issue.1 , pp. 67-75
    • Tsutsui, S.1    Ohno, S.2    Murakami, S.3    Hachitanda, Y.4    Oda, S.5
  • 92
    • 25844467036 scopus 로고    scopus 로고
    • Overview of tyrosine kinase inhibitors in clinical breast cancer
    • DOI 10.1677/erc.1.01059, Growth Factor Signalling snd Therapeutic Resistance in Breast Cancer
    • Agrawal A, Gutteridge E, Gee JM, Nicholson RI, Robertson JF. Overview of tyrosine kinase inhibitors in clinical breast cancer. Endocr. Relat. Cancer 12(Suppl. 1), S135-S144 (2005). (Pubitemid 41395421)
    • (2005) Endocrine-Related Cancer , vol.12 , Issue.SUPPL. 1
    • Agrawal, A.1    Gutteridge, E.2    Gee, J.M.W.3    Nicholson, R.I.4    Robertson, J.F.R.5
  • 94
    • 69849105168 scopus 로고    scopus 로고
    • Estrogen receptor, progesterone receptor, human epidermal growth factor receptor 2 HER2 and epidermal growth factor receptor expression and benefit from lapatinib in a randomized trial of paclitaxel with lapatinib or placebo as first-line treatment in HER2-negative or unknown metastatic breast cancer
    • Finn RS, Press MF, Dering J et al. Estrogen receptor, progesterone receptor, human epidermal growth factor receptor 2 (HER2), and epidermal growth factor receptor expression and benefit from lapatinib in a randomized trial of paclitaxel with lapatinib or placebo as first-line treatment in HER2-negative or unknown metastatic breast cancer. J. Clin. Oncol. 27(24), 3908-3915 (2009).
    • (2009) J. Clin. Oncol. , vol.27 , Issue.24 , pp. 3908-3915
    • Finn, R.S.1    Press, M.F.2    Dering, J.3
  • 96
    • 78549278133 scopus 로고    scopus 로고
    • Tyrosine phosphorylation profiling reveals the signaling network characteristics of basal breast cancer cells
    • Hochgrafe F, Zhang L, O'Toole SA et al. Tyrosine phosphorylation profiling reveals the signaling network characteristics of basal breast cancer cells. Cancer Res. 70(22), 9391-9401 (2010).
    • (2010) Cancer Res. , vol.70 , Issue.22 , pp. 9391-9401
    • Hochgrafe, F.1    Zhang, L.2    O'Toole, S.A.3
  • 97
    • 70350540711 scopus 로고    scopus 로고
    • HDAC inhibitor SNDX-275 induces apoptosis in erbB2-overexpressing breast cancer cells via down-regulation of erbB3 expression
    • Huang X, Gao L, Wang S, Lee CK, Ordentlich P, Liu B. HDAC inhibitor SNDX-275 induces apoptosis in erbB2- overexpressing breast cancer cells via down-regulation of erbB3 expression. Cancer Res. 69(21), 8403-8411 (2009).
    • (2009) Cancer Res. , vol.69 , Issue.21 , pp. 8403-8411
    • Huang, X.1    Gao, L.2    Wang, S.3    Lee, C.K.4    Ordentlich, P.5    Liu, B.6
  • 98
    • 22744437647 scopus 로고    scopus 로고
    • HDAC inhibitors enhance the apoptosis-inducing potential of TRAIL in breast carcinoma
    • DOI 10.1038/sj.onc.1208585
    • Singh TR, Shankar S, Srivastava RK. HDAC inhibitors enhance the apoptosis-inducing potential of TRAIL in breast carcinoma. Oncogene 24(29), 4609-4623 (2005). (Pubitemid 41032599)
    • (2005) Oncogene , vol.24 , Issue.29 , pp. 4609-4623
    • Singh, T.R.1    Shankar, S.2    Srivastava, R.K.3
  • 99
    • 79959206030 scopus 로고    scopus 로고
    • Genomic predictors of response to doxorubicin versus docetaxel in primary breast cancer
    • Martin M, Romero A, Cheang MC et al. Genomic predictors of response to doxorubicin versus docetaxel in primary breast cancer. Breast Cancer Res. Treat. 128(1), 127-136 (2011).
    • (2011) Breast Cancer Res. Treat. , vol.128 , Issue.1 , pp. 127-136
    • Martin, M.1    Romero, A.2    Cheang, M.C.3
  • 100
    • 47949130625 scopus 로고    scopus 로고
    • Topoisomerase levels determine chemotherapy response in vitro and in vivo
    • USA
    • Burgess DJ, Doles J, Zender L et al. Topoisomerase levels determine chemotherapy response in vitro and in vivo. Proc. Natl Acad. Sci. USA 105(26), 9053-9058 (2008).
    • (2008) Proc. Natl Acad. Sci. , vol.105 , Issue.26 , pp. 9053-9058
    • Burgess, D.J.1    Doles, J.2    Zender, L.3
  • 101
    • 79955008762 scopus 로고    scopus 로고
    • Multifactorial approach to predicting resistance to anthracyclines
    • Desmedt C, Di Leo A, de Azambuja E et al. Multifactorial approach to predicting resistance to anthracyclines. J. Clin. Oncol. 29(12), 1578-1586 (2011).
    • (2011) J. Clin. Oncol. , vol.29 , Issue.12 , pp. 1578-1586
    • Desmedt, C.1    Di Leo, A.2    De Azambuja, E.3
  • 103
    • 58149334773 scopus 로고    scopus 로고
    • A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer
    • Farmer P, Bonnefoi H, Anderle P et al. A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer. Nat. Med. 15(1), 68-74 (2009).
    • (2009) Nat. Med. , vol.15 , Issue.1 , pp. 68-74
    • Farmer, P.1    Bonnefoi, H.2    Anderle, P.3
  • 105
    • 69549122386 scopus 로고    scopus 로고
    • Systems biology modeling of the radiation sensitivity network: A biomarker discovery platform
    • Eschrich S, Zhang H, Zhao H et al. Systems biology modeling of the radiation sensitivity network: a biomarker discovery platform. Int. J. Radiat. Oncol. Biol. Phys. 75(2), 497-505 (2009).
    • (2009) Int. J. Radiat. Oncol. Biol. Phys. , vol.75 , Issue.2 , pp. 497-505
    • Eschrich, S.1    Zhang, H.2    Zhao, H.3
  • 106
    • 69449090120 scopus 로고    scopus 로고
    • Thresholds for therapies: Highlights of the St gallen international expert consensus on the primary therapy of early breast cancer 2009
    • Goldhirsch A, Ingle JN, Gelber RD, Coates AS, Thurlimann B, Senn HJ. Thresholds for therapies: highlights of the St Gallen International Expert Consensus on the primary therapy of early breast cancer 2009. Ann. Oncol. 20(8), 1319-1329 (2009).
    • (2009) Ann. Oncol. , vol.20 , Issue.8 , pp. 1319-1329
    • Goldhirsch, A.1    Ingle, J.N.2    Gelber, R.D.3    Coates, A.S.4    Thurlimann, B.5    Senn, H.J.6


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