Modified Wu-Zi-Yan-Zong prescription, a traditional Chinese polyherbal formula, suppresses lipopolysaccharide-induced neuroinflammatory processes in rat astrocytes via NF-κB and JNK/p38 MAPK signaling pathways

Phytomedicine

Volumn 19, Issue 2, 2012, Pages 122-129

  Zeng, Ke Wu ^a   Zhang, Tai ^a   Fu, Hong ^a   Liu, Geng Xin ^a   Wang, Xue Mei ^a  

^a PEKING UNIVERSITY   (China)

Author keywords

Astrocyte; HPLC analysis; Lipopolysaccharide; Modified Wu Zi Yan Zong prescription; Neuroinflammation; Traditional Chinese medicine

Indexed keywords

CHINESE DRUG; CYCLOOXYGENASE 2; I KAPPA B; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; MODIFIED WU ZI YAN ZONG PRESCRIPTION; NITRIC OXIDE; PROSTAGLANDIN E; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASTROCYTE; CHEMICAL COMPOSITION; CHINESE HERB; COCULTURE; CONTROLLED STUDY; DEGENERATIVE DISEASE; DOWN REGULATION; DRUG MECHANISM; ENZYME PHOSPHORYLATION; GENE EXPRESSION REGULATION; INFLAMMATION; NERVE CELL CULTURE; NEUROINFLAMMATION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ASTROCYTES; BLOTTING, WESTERN; CELL SURVIVAL; COCULTURE TECHNIQUES; DRUGS, CHINESE HERBAL; GENE EXPRESSION REGULATION; INFLAMMATION; LIPOPOLYSACCHARIDES; MAP KINASE SIGNALING SYSTEM; NEURONS; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PRIMARY CELL CULTURE; PROSTAGLANDINS E; RATS; RATS, SPRAGUE-DAWLEY;

RATTUS;

EID: 83655201395     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2011.08.003     Document Type: Article

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