A protective role for inflammasome activation following injury

Shock

Volumn 37, Issue 1, 2012, Pages 47-55

  Osuka, Akinori ^a   Hanschen, Marc ^a   Stoecklein, Veit ^a   Lederer, James A ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

damage associated molecular patterns; danger; IL 1 ; IL 18; IL 33; Trauma

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; CD4 ANTIGEN; INFLAMMASOME; INTERLEUKIN 1BETA CONVERTING ENZYME; LIPOPOLYSACCHARIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; BURN; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DENDRITIC CELL; FLOW CYTOMETRY; IMMUNOCOMPETENT CELL; IN VIVO STUDY; INJURY; LYMPH NODE; LYMPH NODE BIOPSY; MACROPHAGE; MALE; MOUSE; NATURAL KILLER CELL; NONHUMAN; PROTECTION; SHAM PROCEDURE; SPLEEN BIOPSY; SPLEEN CELL; STAINING; TISSUE REACTION;

ANIMALS; BURNS; CASPASE 1; ENZYME ACTIVATION; INFLAMMASOMES; LYMPH NODES; LYMPHOCYTES; MACROPHAGES; MALE; MICE; PROTEASE INHIBITORS; SPLEEN;

EID: 83655191976     PISSN: 10732322     EISSN: 15400514     Source Type: Journal    
DOI: 10.1097/SHK.0b013e318234f7ff     Document Type: Article

References (30)

1. Hoover L, Bochicchio GV, Napolitano LM, Joshi M, Bochicchio K, Meyer W, Scalea TM: Systemic inflammatory response syndrome and nosocomial infection in trauma. J Trauma 61(2):310-316; discussion 316-317, 2006. (Pubitemid 44265808)
2. Sauaia A, Moore FA, Moore EE, Lezotte DC: Early risk factors for postinjury multiple organ failure. World J Surg 20(4):392-400, 1996. (Pubitemid 26138584)
3. Martinon F, Mayor A, Tschopp J: The inflammasomes: guardians of the body. Annu Rev Immunol 27:229-265, 2009.
4. Rock KL, Hearn A, Chen CJ, Shi Y: Natural endogenous adjuvants. Springer Semin Immunopathol 26(3):231-246, 2005.
5. Shi Y, Evans JE, Rock KL: Molecular identification of a danger signal that alerts the immune system to dying cells. Nature 425(6957):516-521, 2003. (Pubitemid 37237047)
6. Arend WP, Palmer G, Gabay C: IL-1, IL-18, and IL-33 families of cytokines. Immunol Rev 223:20-38, 2008. (Pubitemid 351986169)
7. Zedler S, Faist E: The impact of endogenous triggers on trauma-associated inflammation. Curr Opin Crit Care 12(6):595-601, 2006. (Pubitemid 44673437)
8. Fujimi S, Lapchak PH, Zang Y, MacConmara MP, Maung AA, Delisle AJ, Mannick JA, Lederer JA: Murine dendritic cell antigen-presenting cell function is not altered by burn injury. J Leukoc Biol 85(5):862-870, 2009.
9. Vermes I, Haanen C, Steffens-Nakken H, Reutelingsperger CA: Novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled annexin V. J Immunol Methods 184(1):39-51, 1995.
10. Broz P, Newton K, Lamkanfi M, Mariathasan S, Dixit VM, Monack DM: Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella. J Exp Med 207(8):1745-1755, 2010.
11. Rozman-Pungercar J, Kopitar-Jerala N, Bogyo M, Turk D, Vasiljeva O, Stefe I, Vandenabeele P, Bromme D, Puizdar V, Fonovic M, et al.: Inhibition of papainlike cysteine proteases and legumain by caspase-specific inhibitors: when reaction mechanism is more important than specificity. Cell Death Differ 10(8):881-888, 2003. (Pubitemid 36939698)
12. Paterson HM, Murphy TJ, Purcell EJ, Shelley O, Kriynovich SJ, Lien E, Mannick JA, Lederer JA: Injury primes the innate immune system for enhanced Toll-like receptor reactivity. J Immunol 171(3):1473-1483, 2003. (Pubitemid 36900082)
13. Maung AA, Fujimi S, MacConmara MP, Tajima G, McKenna AM, Delisle AJ, Stallwood C, Onderdonk AB, Mannick JA, Lederer JA: Injury enhances resistance to Escherichia coli infection by boosting innate immune system function. J Immunol 180(4):2450-2458, 2008.
14. Li H, Ambade A, Re F: Cutting edge: necrosis activates the NLRP3 inflammasome. J Immunol 183(3):1528-1532, 2009.
15. Gasse P, Riteau N, Charron S, Girre S, Fick L, Petrilli V, Tschopp J, Lagente V, Quesniaux VF, Ryffel B, et al.: Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis. Am J Respir Crit Care Med 179(10):903-913, 2009.
16. Franchi L, Eigenbrod T, Munoz-Planillo R, Nunez G: The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis. Nat Immunol 10(3):241-247, 2009.
17. Matzinger P: The danger model: a renewed sense of self. Science 296(5566): 301-305, 2002. (Pubitemid 34303674)
18. Seong SY, Matzinger P: Hydrophobicity: an ancient damage-associated molecular pattern that initiates innate immune responses. Nat Rev Immunol 4(6): 469-478, 2004. (Pubitemid 38745558)
19. Bianchi ME: DAMPs, PAMPs and alarmins: all we need to know about danger. J Leukoc Biol 81(1):1-5, 2007. (Pubitemid 46028489)
20. Pedra JH, Cassel SL, Sutterwala FS: Sensing pathogens and danger signals by the inflammasome. Curr Opin Immunol 21(1):10-16, 2009.
21. Iyer SS, Pulskens WP, Sadler JJ, Butter LM, Teske GJ, Ulland TK, Eisenbarth SC, Florquin S, Flavell RA, Leemans JC, et al.: Necrotic cells trigger a sterile inflammatory response through the NLRP3 inflammasome. Proc Natl Acad Sci USA 106(48):20388-20393, 2009.
22. Goncalves GM, Zamboni DS, Camara NO: The role of innate immunity in septic acute kidney injuries. Shock 34(Suppl 1):22-26, 2010.
23. Hasko G, Kuhel DG, Salzman AL, Szabo C: ATP suppression of interleukin-12 and tumour necrosis factor-alpha release from macrophages. Br J Pharmacol 129(5):909-914, 2000. (Pubitemid 30142902)
24. Sozen T, Tsuchiyama R, Hasegawa Y, Suzuki H, Jadhav V, Nishizawa S, Zhang JH: Role of interleukin-1beta in early brain injury after subarachnoid hemorrhage in mice. Stroke 40(7):2519-2525, 2009.
25. Liu HF, Liang D, Wang LM, Zhou N, Yao CW, Hong T, Tang DS, Chen XW: Effects of specific interleukin-1betaYconverting enzyme inhibitor on ischemic acute renal failure in murine models. Acta Pharmacol Sin 26(11): 1345-1351, 2005. (Pubitemid 41607007)
26. Karaoglan A, Kaya E, Akdemir O, Sagmanligil A, Bilguvar K, Cirakoglu B, Sahan E, Erdogan N, Barut AE, Colak A: Neuroprotective effects of Ac.YVAD.cmk on experimental spinal cord injury in rats. Surg Neurol 69(6):561-567, 2008.
27. Abreu MT, Fukata M, Arditi M: TLR signaling in the gut in health and disease. J Immunol 174(8):4453-4460, 2005.
28. Remick DG, Bolgos GR, Siddiqui J, Shin J, Nemzek JA: Six at six: interleukin-6 measured 6 h after the initiation of sepsis predicts mortality over 3 days. Shock 17(6):463-467, 2002.
29. Oboki K, Ohno T, Kajiwara N, Arae K, Morita H, Ishii A, Nambu A, Abe T, Kiyonari H, Matsumoto K, et al.: IL-33 is a crucial amplifier of innate rather than acquired immunity. Proc Natl Acad Sci USA 107(43):18581-18586, 2010.
30. Pushparaj PN, Tay HK, H'Ng SC, Pitman N, Xu D, McKenzie A, Liew FY, Melendez AJ: The cytokine interleukin-33 mediates anaphylactic shock. Proc Natl Acad Sci USA 106(24):9773-9778, 2009.