Relationships between liposome properties, cell membrane binding, intracellular processing, and intracellular bioavailability

AAPS Journal

Volumn 13, Issue 4, 2011, Pages 585-597

  Li, Yinghuan ^a,b   Wang, Jie ^b   Gao, Yue ^b   Zhu, Jiabi ^a   Wientjes, M Guillaume ^b   Au, Jessie L S ^b  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

cationic liposomes; internalization; membrane binding; pegylation; zeta potential

Indexed keywords

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; 1,2 DIOLEOYL SN GLYCERO 3 PHOSPHOETHANOLAMINE; DIPALMITOYLPHOSPHATIDYLCHOLINE; LIPOSOME; UNCLASSIFIED DRUG;

ARTICLE; BIOAVAILABILITY; CHEMICAL PROCEDURES; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DISPERSION; ENDOSOME; HUMAN; HUMAN CELL; INTERNALIZATION; INTRACELLULAR BIOAVAILABILITY; INTRACELLULAR SPACE; INTRACELLULAR TRANSPORT; MEMBRANE BINDING; PEGYLATION; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; SURFACE CHARGE; ZETA POTENTIAL;

BIOLOGICAL AVAILABILITY; CELL LINE, TUMOR; CELL MEMBRANE; HUMANS; LIPOSOMES; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; POLYETHYLENE GLYCOLS;

EID: 83555174734     PISSN: 15507416     EISSN: None     Source Type: Journal    
DOI: 10.1208/s12248-011-9298-1     Document Type: Article

References (28)

1. J Wang Z Lu MG Wientjes JL Au 2010 Delivery of siRNA Therapeutics: Barriers and Carriers AAPS J 12 4 492 503 20544328 10.1208/s12248-010-9210-4 1:CAS:528:DC%2BC3cXhsFCqsbfN
2. KD Fisher K Ulbrich V Subr CM Ward V Mautner D Blakey, et al. 2000 A versatile system for receptor-mediated gene delivery permits increased entry of DNA into target cells, enhanced delivery to the nucleus and elevated rates of transgene expression Gene Ther 7 15 1337 1343 10918506 10.1038/sj.gt.3301230 1:CAS:528:DC%2BD3cXlsVelsLo%3D (Pubitemid 30623782)
3. B Li S Li Y Tan DB Stolz SC Watkins LH Block, et al. 2000 Lyophilization of cationic lipid-protamine-DNA (LPD) complexes J Pharm Sci 89 3 355 364 10707016 10.1002/(SICI)1520-6017(200003)89:3<355::AID-JPS7>3.0.CO;2-H 1:CAS:528:DC%2BD3cXit1KntL8%3D (Pubitemid 30152436)
4. YC Tseng S Mozumdar L Huang 2009 Lipid-based systemic delivery of siRNA Adv Drug Deliv Rev 61 9 721 731 19328215 10.1016/j.addr.2009.03.003 1:CAS:528:DC%2BD1MXmsFyns7Y%3D
5. SY Wu NA McMillan 2009 Lipidic systems for in vivo siRNA delivery AAPS J 11 4 639 652 19757082 10.1208/s12248-009-9140-1 1:CAS:528:DC%2BD1MXhsFGmur%2FF
6. IA Khalil K Kogure H Akita H Harashima 2006 Uptake pathways and subsequent intracellular trafficking in nonviral gene delivery Pharmacol Rev 58 1 32 45 16507881 10.1124/pr.58.1.8 1:CAS:528:DC%2BD28XjtlCqsLw%3D
7. IA Khalil K Kogure S Futaki H Harashima 2006 High density of octaarginine stimulates macropinocytosis leading to efficient intracellular trafficking for gene expression J Biol Chem 281 6 3544 3551 16326716 10.1074/jbc.M503202200 1:CAS:528:DC%2BD28XhtFSmtrw%3D (Pubitemid 43845971)
8. AK Iyer G Khaled J Fang H Maeda 2006 Exploiting the enhanced permeability and retention effect for tumor targeting Drug Discov Today 11 17-18 812 818 16935749 10.1016/j.drudis.2006.07.005 1:CAS:528:DC%2BD28XoslOgtLo%3D (Pubitemid 44280021)
9. A Gabizon H Shmeeda Y Barenholz 2003 Pharmacokinetics of pegylated liposomal Doxorubicin: review of animal and human studies Clin Pharmacokinet 42 5 419 436 12739982 10.2165/00003088-200342050-00002 1:CAS:528: DC%2BD3sXkvFOjsrY%3D (Pubitemid 36649037)
10. N Dos Santos C Allen AM Doppen M Anantha KAK Cox RC Gallagher, et al. 2007 Influence of poly(ethylene glycol) grafting density and polymer length on liposomes: Relating plasma circulation lifetimes to protein binding Biochim Biophys Acta 1768 6 1367 1377 17400180 10.1016/j.bbamem.2006.12.013 (Pubitemid 46782695)
11. AK Kenworthy K Hristova D Needham TJ McIntosh 1995 Range and magnitude of the steric pressure between bilayers containing phospholipids with covalently attached poly(ethylene glycol) Biophys J 68 5 1921 1936 7612834 10.1016/S0006-3495(95)80369-3 1:CAS:528:DyaK2MXlt1KgsLk%3D
12. SD Li L Huang 2008 Pharmacokinetics and biodistribution of nanoparticles Mol Pharm 5 4 496 504 18611037 10.1021/mp800049w 1:CAS:528:DC%2BD1cXot1ersr8%3D
13. Z Ma J Li F He A Wilson B Pitt S Li 2005 Cationic lipids enhance siRNA-mediated interferon response in mice Biochem Biophys Res Commun 330 3 755 759 15809061 10.1016/j.bbrc.2005.03.041 1:CAS:528:DC%2BD2MXivV2jtL8%3D (Pubitemid 40462151)
14. Y Zhang TJ Anchordoquy 2004 The role of lipid charge density in the serum stability of cationic lipid/DNA complexes Biochim Biophys Acta 1663 1-2 143 157 15157617 1:CAS:528:DC%2BD2cXkt1Smt7k%3D (Pubitemid 38625589)
15. DJ Porteous JR Dorin G McLachlan H Davidson-Smith H Davidson BJ Stevenson, et al. 1997 Evidence for safety and efficacy of DOTAP cationic liposome mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis Gene Ther 4 3 210 218 9135734 10.1038/sj.gt.3300390 1:CAS:528:DyaK2sXhvFSjurg%3D (Pubitemid 27182074)
16. S Simoes JN Moreira C Fonseca N Duzgunes MCP de Lima 2004 On the formulation of pH-sensitive long circulation times Adv Drug Deliv Rev 56 7 947 965 15066754 10.1016/j.addr.2003.10.038 1:CAS:528:DC%2BD2cXivVGitLg%3D (Pubitemid 38520203)
17. T Yang FD Cui MK Choi JW Cho SJ Chung CK Shim, et al. 2007 Enhanced solubility and stability of PEGylated liposomal paclitaxel: in vitro and in vivo evaluation Int J Pharm 338 1-2 317 326 17368984 10.1016/j.ijpharm.2007.02.011 1:CAS:528:DC%2BD2sXlslWgsLs%3D (Pubitemid 46777245)
18. SK Hobbs WL Monsky F Yuan WG Roberts L Griffith VP Torchilin, et al. 1998 Regulation of transport pathways in tumor vessels: Role of tumor type and microenvironment Proc Natl Acad Sci USA 95 8 4607 4612 9539785 10.1073/pnas.95.8.4607 1:CAS:528:DyaK1cXis1OgsLc%3D (Pubitemid 28207960)
19. F Yuan M Dellian D Fukumura M Leunig DA Berk VP Torchilin, et al. 1995 Vascular-Permeability in A Human Tumor Xenograft - Molecular-Size Dependence and Cutoff Size Cancer Res 55 17 3752 3756 7641188 1:CAS:528:DyaK2MXnvVelsLc%3D
20. N Duzgunes S Nir 1999 Mechanisms and kinetics of liposome-cell interactions Adv Drug Deliv Rev 40 1-2 3 18 10.1016/S0169-409X(99)00037-X 1:CAS:528:DyaK1MXmsFajsLo%3D (Pubitemid 29486601)
21. KD Lee S Nir D Papahadjopoulos 1993 Quantitative analysis of liposome-cell interactions in vitro: rate constants of binding and endocytosis with suspension and adherent J774 cells and human monocytes Biochemistry 32 3 889 899 8422393 10.1021/bi00054a021 1:CAS:528:DyaK3sXksFKmsA%3D%3D (Pubitemid 23059371)
22. I Wrobel D Collins 1995 Fusion of cationic liposomes with mammalian cells occurs after endocytosis Biochim Biophys Acta 1235 2 296 304 7756338 10.1016/0005-2736(95)80017-A
23. MG Qaddoumi H Ueda J Yang J Davda V Labhasetwar VHL Lee 2004 The characteristics and mechanisms of uptake of PLGA nanoparticles in rabbit conjunctival epithelial cell layers Pharm Res 21 4 641 648 15139521 10.1023/B:PHAM.0000022411.47059.76 1:CAS:528:DC%2BD2cXjsVWqs7s%3D (Pubitemid 38457287)
24. WL Hinrichs FA Mancenido NN Sanders K Braeckmans SC De Smedt J Demeester, et al. 2006 The choice of a suitable oligosaccharide to prevent aggregation of PEGylated nanoparticles during freeze thawing and freeze drying Int J Pharm 311 1-2 237 244 16442758 10.1016/j.ijpharm.2005.12.032 1:CAS:528: DC%2BD28XhvF2lsrY%3D
25. T Gjetting NS Arildsen CL Christensen TT Poulsen JA Roth VN Handlos, et al. 2010 In vitro and in vivo effects of polyethylene glycol (PEG)-modified lipid in DOTAP/cholesterol-mediated gene transfection Int J Nanomedicine 5 371 383 20957159 1:CAS:528:DC%2BC3cXntVGqsbk%3D
26. J Rejman A Bragonzi M Conese 2005 Role of clathrin- and caveolae-mediated endocytosis in gene transfer mediated by lipo- and polyplexes Mol Ther 12 3 468 474 15963763 10.1016/j.ymthe.2005.03.038 1:CAS:528:DC%2BD2MXos1agsrY%3D (Pubitemid 41150132)
27. CR Miller B Bondurant SD Mclean KA McGovern DF O'Brien 1998 Liposome-cell interactions in vitro: Effect of liposome surface charge on the binding and endocytosis of conventional and sterically stabilized liposomes Biochemistry 37 37 12875 12883 9737866 10.1021/bi980096y 1:CAS:528:DyaK1cXlsVKmtb8%3D (Pubitemid 28433520)
28. A Santel M Aleku O Keil J Endruschat V Esche G Fisch, et al. 2006 A novel siRNA-lipoplex technology for RNA interference in the mouse vascular endothelium Gene Ther 13 16 1222 1234 16625243 10.1038/sj.gt.3302777 1:CAS:528:DC%2BD28Xnsl2hu7g%3D (Pubitemid 44184716)