A versatile system for receptor-mediated gene delivery permits increased entry of DNA into target cells, enhanced delivery to the nucleus and elevated rates of transgene expression

Gene Therapy

Volumn 7, Issue 15, 2000, Pages 1337-1343

  Fisher, K D ^a   Ulbrich, K ^b   Subr, V ^b   Ward, C M ^a   Mautner, V ^a   Blakey, D ^c   Seymour, L W ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b INSTITUTE OF MACROMOLECULAR CHEMISTRY   (Czech Republic)

^c ASTRAZENECA   (United Kingdom)

Author keywords

BFGF; Endothelial cells; Gene delivery; HUVE cells; Polymer; Transferrin

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; COPOLYMER; DEOXYCYTIDINE TRIPHOSPHATE; DNA; LIGAND; N (2 HYDROXYPROPYL)METHACRYLAMIDE; NANOPARTICLE; PHOSPHORUS 32; PLASMA PROTEIN; PLASMID DNA; POLYELECTROLYTE; POLYLYSINE; POLY[N (2 HYDROXYPROPYL)METHACRYLAMIDE]; TRANSFERRIN; VASCULOTROPIN;

ARTICLE; BIODEGRADATION; CELL NUCLEUS; CELL SPECIFICITY; CLONING VECTOR; CONTROLLED STUDY; CROSS LINKING; CYTOPLASM; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; TARGET CELL; TRANSGENE;

EID: 0033883579     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301230     Document Type: Article

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