-
1
-
-
53049087109
-
Genomic and epigenetic instability in colorectal cancer pathogenesis
-
Grady W.M., Carethers J.M. Genomic and epigenetic instability in colorectal cancer pathogenesis. Gastroenterology 2008, 135:1079-1099.
-
(2008)
Gastroenterology
, vol.135
, pp. 1079-1099
-
-
Grady, W.M.1
Carethers, J.M.2
-
2
-
-
0027314411
-
Microsatellite instability in cancer of the proximal colon
-
Thibodeau S.N., Bren G., Schaid D. Microsatellite instability in cancer of the proximal colon. Science 1993, 260:816-819.
-
(1993)
Science
, vol.260
, pp. 816-819
-
-
Thibodeau, S.N.1
Bren, G.2
Schaid, D.3
-
3
-
-
0028785603
-
Microsatellite instability and mutations of the transforming growth factor beta type II receptor gene in colorectal cancer
-
Parsons R., Myeroff L.L., Liu B., Willson J.K., Markowitz S.D., Kinzler K.W., Vogelstein B. Microsatellite instability and mutations of the transforming growth factor beta type II receptor gene in colorectal cancer. Cancer Res. 1995, 55:5548-5550.
-
(1995)
Cancer Res.
, vol.55
, pp. 5548-5550
-
-
Parsons, R.1
Myeroff, L.L.2
Liu, B.3
Willson, J.K.4
Markowitz, S.D.5
Kinzler, K.W.6
Vogelstein, B.7
-
4
-
-
0033984095
-
Involvement of PTEN mutations in the genetic pathways of colorectal cancerogenesis
-
Guanti G., Resta N., Simone C., Cariola F., Demma I.I., Fiorente P.P., Gentile M. Involvement of PTEN mutations in the genetic pathways of colorectal cancerogenesis. Hum. Mol. Genet. 2000, 9:283-287.
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 283-287
-
-
Guanti, G.1
Resta, N.2
Simone, C.3
Cariola, F.4
Demma, I.I.5
Fiorente, P.P.6
Gentile, M.7
-
5
-
-
0035881961
-
Instabilotyping: comprehensive identification of frameshift mutations caused by coding region microsatellite instability
-
Mori Y., Yin J., Rashid A., Leggett B.A., Young J., Simms L., Kuehl P.M., Langenberg P., Meltzer S.J., Stine O.C. Instabilotyping: comprehensive identification of frameshift mutations caused by coding region microsatellite instability. Cancer Res. 2001, 61:6046-6049.
-
(2001)
Cancer Res.
, vol.61
, pp. 6046-6049
-
-
Mori, Y.1
Yin, J.2
Rashid, A.3
Leggett, B.A.4
Young, J.5
Simms, L.6
Kuehl, P.M.7
Langenberg, P.8
Meltzer, S.J.9
Stine, O.C.10
-
6
-
-
1542377485
-
Loss of activin receptor type 2 protein expression in microsatellite unstable colon cancers
-
Jung B., Doctolero R.T., Tajima A., Nguyen A.K., Keku T., Sandler R.S., Carethers J.M. Loss of activin receptor type 2 protein expression in microsatellite unstable colon cancers. Gastroenterology 2004, 126:654-659.
-
(2004)
Gastroenterology
, vol.126
, pp. 654-659
-
-
Jung, B.1
Doctolero, R.T.2
Tajima, A.3
Nguyen, A.K.4
Keku, T.5
Sandler, R.S.6
Carethers, J.M.7
-
7
-
-
20944440949
-
Microsatellite instability of selective target genes in HNPCC-associated colon adenomas
-
Woerner S.M., Kloor M., Mueller A., Rueschoff J., Friedrichs N., Buettner R., Buzello M., Kienle P., Knaebel H.P., Kunstmann E., Pagenstecher C., Schackert H.K., Moslein G., Vogelsang H., von Knebel Doeberitz M., Gebert J.F. Microsatellite instability of selective target genes in HNPCC-associated colon adenomas. Oncogene 2005, 24:2525-2535.
-
(2005)
Oncogene
, vol.24
, pp. 2525-2535
-
-
Woerner, S.M.1
Kloor, M.2
Mueller, A.3
Rueschoff, J.4
Friedrichs, N.5
Buettner, R.6
Buzello, M.7
Kienle, P.8
Knaebel, H.P.9
Kunstmann, E.10
Pagenstecher, C.11
Schackert, H.K.12
Moslein, G.13
Vogelsang, H.14
von Knebel Doeberitz, M.15
Gebert, J.F.16
-
8
-
-
0027742295
-
The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer
-
Fishel R., Lescoe M.K., Rao M.R., Copeland N.G., Jenkins N.A., Garber J., Kane M., Kolodner R. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell 1993, 75:1027-1038.
-
(1993)
Cell
, vol.75
, pp. 1027-1038
-
-
Fishel, R.1
Lescoe, M.K.2
Rao, M.R.3
Copeland, N.G.4
Jenkins, N.A.5
Garber, J.6
Kane, M.7
Kolodner, R.8
-
9
-
-
0028350601
-
Mutation of a mutL homolog in hereditary colon cancer
-
Papadopoulos N., Nicolaides N.C., Wei Y.F., Ruben S.M., Carter K.C., Rosen C.A., Haseltine W.A., Fleischmann R.D., Fraser C.M., Adams M.D.M.D. Mutation of a mutL homolog in hereditary colon cancer. Science 1994, 263:1625-1629.
-
(1994)
Science
, vol.263
, pp. 1625-1629
-
-
Papadopoulos, N.1
Nicolaides, N.C.2
Wei, Y.F.3
Ruben, S.M.4
Carter, K.C.5
Rosen, C.A.6
Haseltine, W.A.7
Fleischmann, R.D.8
Fraser, C.M.9
Adams, M.D.M.D.10
-
10
-
-
0030465237
-
HMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6
-
Acharya S., Wilson T., Gradia S., Kane M.F., Guerrette S., Marsischky G.T., Kolodner R., Fishel R. hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6. Proc. Natl. Acad. Sci. U.S.A. 1996, 93:13629-13634.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, pp. 13629-13634
-
-
Acharya, S.1
Wilson, T.2
Gradia, S.3
Kane, M.F.4
Guerrette, S.5
Marsischky, G.T.6
Kolodner, R.7
Fishel, R.8
-
11
-
-
0029659046
-
HMutSbeta, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA
-
Palombo F., Iaccarino I., Nakajima E., Ikejima M., Shimada T., Jiricny J. hMutSbeta, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA. Curr. Biol. 1996, 6:1181-1184.
-
(1996)
Curr. Biol.
, vol.6
, pp. 1181-1184
-
-
Palombo, F.1
Iaccarino, I.2
Nakajima, E.3
Ikejima, M.4
Shimada, T.5
Jiricny, J.6
-
12
-
-
0032527704
-
Mismatch repair, molecular switches, and signal transduction
-
Fishel R. Mismatch repair, molecular switches, and signal transduction. Genes Dev. 1998, 12:2096-2101.
-
(1998)
Genes Dev.
, vol.12
, pp. 2096-2101
-
-
Fishel, R.1
-
13
-
-
33646391241
-
Influence of target gene mutations on survival, stage and histology in sporadic microsatellite unstable colon cancers
-
Jung B., Smith E.J., Doctolero R.T., Gervaz P., Alonso J.C., Miyai K.K., Keku T., Sandler R.S., Carethers J.M. Influence of target gene mutations on survival, stage and histology in sporadic microsatellite unstable colon cancers. Int. J. Cancer 2006, 118:2509-2513.
-
(2006)
Int. J. Cancer
, vol.118
, pp. 2509-2513
-
-
Jung, B.1
Smith, E.J.2
Doctolero, R.T.3
Gervaz, P.4
Alonso, J.C.5
Miyai, K.K.6
Keku, T.7
Sandler, R.S.8
Carethers, J.M.9
-
14
-
-
33750083332
-
Mechanisms in eukaryotic mismatch repair
-
Modrich P. Mechanisms in eukaryotic mismatch repair. J. Biol. Chem. 2006, 281:30305-30309.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 30305-30309
-
-
Modrich, P.1
-
15
-
-
0037374547
-
Evidence of selection for clones having genetic inactivation of the activin A type II receptor (ACVR2) gene in gastrointestinal cancers
-
Hempen P.M., Zhang L., Bansal R.K., Iacobuzio-Donahue C.A., Murphy K.M., Maitra A., Vogelstein B., Whitehead R.H., Markowitz S.D., Willson J.K., Yeo C.J., Hruban R.H., Kern S.E. Evidence of selection for clones having genetic inactivation of the activin A type II receptor (ACVR2) gene in gastrointestinal cancers. Cancer Res. 2003, 63:994-999.
-
(2003)
Cancer Res.
, vol.63
, pp. 994-999
-
-
Hempen, P.M.1
Zhang, L.2
Bansal, R.K.3
Iacobuzio-Donahue, C.A.4
Murphy, K.M.5
Maitra, A.6
Vogelstein, B.7
Whitehead, R.H.8
Markowitz, S.D.9
Willson, J.K.10
Yeo, C.J.11
Hruban, R.H.12
Kern, S.E.13
-
16
-
-
54949132907
-
Mutation rates of TGFBR2 and ACVR2 coding microsatellites in human cells with defective DNA mismatch repair
-
Chung H., Young D.J., Lopez C.G., Le T.A., Lee J.K., Ream-Robinson D., Huang S.C., Carethers J.M. Mutation rates of TGFBR2 and ACVR2 coding microsatellites in human cells with defective DNA mismatch repair. PLoS ONE 2008, 3:e3463.
-
(2008)
PLoS ONE
, vol.3
-
-
Chung, H.1
Young, D.J.2
Lopez, C.G.3
Le, T.A.4
Lee, J.K.5
Ream-Robinson, D.6
Huang, S.C.7
Carethers, J.M.8
-
17
-
-
77951094233
-
Flanking sequence specificity determines coding microsatellite heteroduplex and mutation rates with defective DNA mismatch repair (MMR)
-
Chung H., Lopez C.G., Young D.J., Lai J.F., Holmstrom J., Ream-Robinson D., Cabrera B.L., Carethers J.M. Flanking sequence specificity determines coding microsatellite heteroduplex and mutation rates with defective DNA mismatch repair (MMR). Oncogene 2010, 29:2172-2180.
-
(2010)
Oncogene
, vol.29
, pp. 2172-2180
-
-
Chung, H.1
Lopez, C.G.2
Young, D.J.3
Lai, J.F.4
Holmstrom, J.5
Ream-Robinson, D.6
Cabrera, B.L.7
Carethers, J.M.8
-
18
-
-
0001641514
-
Mutations of bacteria from virus sensitivity to virus resistance
-
Luria S.E., Delbruck M. Mutations of bacteria from virus sensitivity to virus resistance. Genetics 1943, 28:491-511.
-
(1943)
Genetics
, vol.28
, pp. 491-511
-
-
Luria, S.E.1
Delbruck, M.2
-
19
-
-
77954165537
-
Both microsatellite length and sequence context determine frameshift mutation rates in defective DNA mismatch repair
-
Chung H., Lopez C.G., Holmstrom J., Young D.J., Lai J.F.J.F., Ream-Robinson D., Carethers J.M. Both microsatellite length and sequence context determine frameshift mutation rates in defective DNA mismatch repair. Hum. Mol. Genet. 2010, 19:2638-2647.
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 2638-2647
-
-
Chung, H.1
Lopez, C.G.2
Holmstrom, J.3
Young, D.J.4
Lai, J.F.J.F.5
Ream-Robinson, D.6
Carethers, J.M.7
-
20
-
-
0033599013
-
Somatic frameshift mutations in the MBD4 gene of sporadic colon cancers with mismatch repair deficiency
-
Bader S., Walker M., Hendrich B., Bird A., Bird C., Hooper M., Wyllie A. Somatic frameshift mutations in the MBD4 gene of sporadic colon cancers with mismatch repair deficiency. Oncogene 1999, 18:8044-8047.
-
(1999)
Oncogene
, vol.18
, pp. 8044-8047
-
-
Bader, S.1
Walker, M.2
Hendrich, B.3
Bird, A.4
Bird, C.5
Hooper, M.6
Wyllie, A.7
-
21
-
-
0042334602
-
There is no increase in frequency of somatic mutations in metastases compared with primary colorectal carcinomas with microsatellite instability
-
Barnetson R., Eckstein R., Robinson B., Schnitzler M. There is no increase in frequency of somatic mutations in metastases compared with primary colorectal carcinomas with microsatellite instability. Genes Chromosomes Cancer 2003, 38:149-156.
-
(2003)
Genes Chromosomes Cancer
, vol.38
, pp. 149-156
-
-
Barnetson, R.1
Eckstein, R.2
Robinson, B.3
Schnitzler, M.4
-
22
-
-
0029741089
-
Frameshift mutator mutations
-
Malkhosyan S., Rampino N., Yamamoto H., Perucho M.M. Frameshift mutator mutations. Nature 1996, 382:499-500.
-
(1996)
Nature
, vol.382
, pp. 499-500
-
-
Malkhosyan, S.1
Rampino, N.2
Yamamoto, H.3
Perucho, M.M.4
-
23
-
-
0031018674
-
Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype
-
Rampino N., Yamamoto H., Ionov Y., Li Y., Sawai H., Reed J.C., Perucho M. Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype. Science 1997, 275:967-969.
-
(1997)
Science
, vol.275
, pp. 967-969
-
-
Rampino, N.1
Yamamoto, H.2
Ionov, Y.3
Li, Y.4
Sawai, H.5
Reed, J.C.6
Perucho, M.7
-
24
-
-
0344417114
-
Frameshift mutations at mononucleotide repeats in caspase-5 and other target genes in endometrial and gastrointestinal cancer of the microsatellite mutator phenotype
-
Schwartz S., Yamamoto H., Navarro M., Maestro M., Reventos J., Perucho M. Frameshift mutations at mononucleotide repeats in caspase-5 and other target genes in endometrial and gastrointestinal cancer of the microsatellite mutator phenotype. Cancer Res. 1999, 59:2995-3002.
-
(1999)
Cancer Res.
, vol.59
, pp. 2995-3002
-
-
Schwartz, S.1
Yamamoto, H.2
Navarro, M.3
Maestro, M.4
Reventos, J.5
Perucho, M.6
-
25
-
-
16144368515
-
Microsatellite instability in the insulin-like growth factor II receptor gene in gastrointestinal tumors
-
Souza R.F., Appel R., Yin J., Wang S., Smolinski K.N., Abraham J.M., Zou T.T., Shi Y.Q., Lei J., Cottrell J., Cymes K., Biden K., Simms L., Leggett B., Lynch P.M., Frazier M., Powell S.M., Harpaz N., Sugimura H., Young J., Meltzer S.J. Microsatellite instability in the insulin-like growth factor II receptor gene in gastrointestinal tumors. Nat. Genet. 1996, 14:255-257.
-
(1996)
Nat. Genet.
, vol.14
, pp. 255-257
-
-
Souza, R.F.1
Appel, R.2
Yin, J.3
Wang, S.4
Smolinski, K.N.5
Abraham, J.M.6
Zou, T.T.7
Shi, Y.Q.8
Lei, J.9
Cottrell, J.10
Cymes, K.11
Biden, K.12
Simms, L.13
Leggett, B.14
Lynch, P.M.15
Frazier, M.16
Powell, S.M.17
Harpaz, N.18
Sugimura, H.19
Young, J.20
Meltzer, S.J.21
more..
|