Flanking sequence specificity determines coding microsatellite heteroduplex and mutation rates with defective DNA mismatch repair (MMR)

Oncogene

Volumn 29, Issue 15, 2010, Pages 2172-2180

  Chung, H ^a   Lopez, C ^a   Young, D ^b   Lai, J ^a   Holmstrom, J ^a   Ream Robinson, D ^a   Cabrera, B ^a   Carethers, J M ^a,b,c  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

Author keywords

ACVR2; Colonic tumors; Frameshift mutation; Microsatellite; Microsatellite instability; MMR

Indexed keywords

ENHANCED GREEN FLUORESCENT PROTEIN; HETERODUPLEX; MICROSATELLITE DNA;

ARTICLE; COLON CANCER; COLON CARCINOGENESIS; CONTROLLED STUDY; DNA FLANKING REGION; FRAMESHIFT MUTATION; HUMAN; HUMAN CELL; MICROSATELLITE INSTABILITY; MISMATCH REPAIR; MOLECULAR RECOGNITION; MUTATION RATE; PRIORITY JOURNAL;

ACTIVIN RECEPTORS, TYPE II; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; BASE PAIR MISMATCH; BASE SEQUENCE; CELL LINE, TUMOR; DNA REPAIR; DNA, INTERGENIC; EXONS; HUMANS; MICROSATELLITE REPEATS; MUTAGENESIS; NUCLEAR PROTEINS;

EID: 77951094233     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2009.508     Document Type: Article

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