Both microsatellite length and sequence context determine frameshift mutation rates in defective DNA mismatch repair

Human Molecular Genetics

Volumn 19, Issue 13, 2010, Pages 2638-2647

  Chung, Heekyung ^a   Lopez, Claudia G ^a   Holmstrom, Joy ^a   Young, Dennis J ^b   Lai, Jenny F ^a   Ream Robinson, Deena ^a   Carethers, John M ^a,b,c  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN RECEPTOR 2; DNA; ENHANCED GREEN FLUORESCENT PROTEIN; PROTEIN MLH1; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; GREEN FLUORESCENT PROTEIN; MICROSATELLITE DNA; PROTEIN SERINE THREONINE KINASE; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA TYPE II RECEPTOR; TRANSFORMING GROWTH FACTOR-BETA TYPE II RECEPTOR;

ARTICLE; CELL CULTURE; CELL SELECTION; COLORECTAL CANCER; CONTROLLED STUDY; DNA REPAIR; DNA SEQUENCE; EXON; FRAMESHIFT MUTATION; GENE MUTATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MISMATCH REPAIR; MOLECULAR CLONING; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE ANALYSIS; GENETICS; NUCLEOTIDE SEQUENCE; TUMOR CELL LINE;

ACTIVIN RECEPTORS, TYPE II; BASE SEQUENCE; CELL LINE, TUMOR; DNA MISMATCH REPAIR; FRAMESHIFT MUTATION; GREEN FLUORESCENT PROTEINS; HUMANS; MICROSATELLITE REPEATS; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA;

EID: 77954165537     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddq151     Document Type: Article

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