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Volumn 44, Issue 1, 2012, Pages 91-100

Apo- and holo-lactoferrin stimulate proliferation of mouse crypt cells but through different cellular signaling pathways

Author keywords

Crypt cells; ERK1 2 pathway; Lactoferrin; Lactoferrin receptor; PI3K Akt pathway

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 MORPHOLINO 8 PHENYLCHROMONE; APOLACTOFERRIN; BROXURIDINE; CYCLIN D1; HOLOLACTOFERRIN; IRON; LACTOFERRIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; UNCLASSIFIED DRUG;

EID: 83555173341     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2011.10.002     Document Type: Article
Times cited : (42)

References (57)
  • 2
    • 3342947832 scopus 로고    scopus 로고
    • Cellular internalization of lactoferrin in intestinal epithelial cells
    • DOI 10.1023/B:BIOM.0000027710.13543.3f
    • K. Ashida, H. Sasaki, Y.A. Suzuki, and B. Lonnerdal Cellular internalization of lactoferrin in intestinal epithelial cells Biometals 17 2004 311 315 (Pubitemid 38987155)
    • (2004) BioMetals , vol.17 , Issue.3 , pp. 311-315
    • Ashida, K.1    Sasaki, H.2    Suzuki, Y.A.3    Lonnerdal, B.4
  • 3
    • 54049141728 scopus 로고    scopus 로고
    • Mitogen-activated protein (MAP) kinase/MAP kinase phosphatase regulation: Roles in cell growth, death, and cancer
    • T. Boutros, E. Chevet, and P. Metrakos Mitogen-activated protein (MAP) kinase/MAP kinase phosphatase regulation: roles in cell growth, death, and cancer Pharmacol Rev 60 2008 261 310
    • (2008) Pharmacol Rev , vol.60 , pp. 261-310
    • Boutros, T.1    Chevet, E.2    Metrakos, P.3
  • 4
    • 0020508495 scopus 로고
    • The effect of trypsin and chymotrypsin on the in vitro antimicrobial and iron-binding properties of lactoferrin in human milk and bovine colostrum. Unusual resistance of human apolactoferrin to proteolytic digestion
    • DOI 10.1016/0304-4165(83)90317-3
    • R.D. Brines, and J.H. Brock The effect of trypsin and chymotrypsin on the in vitro antimicrobial and iron-binding properties of lactoferrin in human milk and bovine colostrum unusual resistance of human apolactoferrin to proteolytic digestion Biochim Biophys Acta 759 1983 229 235 (Pubitemid 13009058)
    • (1983) Biochimica et Biophysica Acta - General Subjects , vol.759 , Issue.3 , pp. 229-235
    • Brines, R.D.1    Brock, J.H.2
  • 5
    • 34147147026 scopus 로고    scopus 로고
    • Lactoferrin induces concentration-dependent functional modulation of intestinal proliferation and differentiation
    • DOI 10.1203/pdr.0b013e3180332c8d
    • V. Buccigrossi, G. de Marco, E. Bruzzese, L. Ombrato, I. Bracale, and G. Polito Lactoferrin induces concentration-dependent functional modulation of intestinal proliferation and differentiation Pediatr Res 61 2007 410 414 (Pubitemid 46569292)
    • (2007) Pediatric Research , vol.61 , Issue.4 , pp. 410-414
    • Buccigrossi, V.1    De Marco, G.2    Bruzzese, E.3    Ombrato, L.4    Bracale, I.5    Polito, G.6    Guarino, A.7
  • 6
    • 83555169859 scopus 로고    scopus 로고
    • Extracellular ATP activates MAP kinase cascades and increases intestinal Caco-2 cell proliferation
    • N. Buzzi, P. Scodelaro Bilbao, R. Boland, and A. Russo de Boland Extracellular ATP activates MAP kinase cascades and increases intestinal Caco-2 cell proliferation Bone 45 2009 S148
    • (2009) Bone , vol.45 , pp. 148
    • Buzzi, N.1    Scodelaro Bilbao, P.2    Boland, R.3    Russo De Boland, A.4
  • 7
    • 0032881288 scopus 로고    scopus 로고
    • AKT/PKB and other D3 phosphoinositide-regulated kinases: Kinase activation by phosphoinositide-dependent phosphorylation
    • DOI 10.1146/annurev.biochem.68.1.965
    • T.O. Chan, S.E. Rittenhouse, and P.N. Tsichlis AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide- dependent phosphorylation Annu Rev Biochem 68 1999 965 1014 (Pubitemid 29449213)
    • (1999) Annual Review of Biochemistry , vol.68 , pp. 965-1014
    • Chan, T.O.1    Rittenhouse, S.E.2    Tsichlis, P.N.3
  • 8
    • 0025014970 scopus 로고
    • Iron retention from lactoferrin-supplemented formulas in infant rhesus monkeys
    • L.A. Davidson, R.E. Litov, and B. Lonnerdal Iron retention from lactoferrin-supplemented formulas in infant rhesus monkeys Pediatr Res 27 1990 176 180 (Pubitemid 20044538)
    • (1990) Pediatric Research , vol.27 , Issue.2 , pp. 176-180
    • Davidson, L.A.1    Litov, R.E.2    Lonnerdal, B.3
  • 9
    • 0022644310 scopus 로고
    • Isolation and characterization of rhesus monkey milk lactoferrin
    • L.A. Davidson, and B. Lonnerdal Isolation and characterization of rhesus monkey milk lactoferrin Pediatr Res 20 1986 197 201 (Pubitemid 16126024)
    • (1986) Pediatric Research , vol.20 , Issue.2 , pp. 197-201
    • Davidson, L.A.1    Lonnerdal, B.2
  • 10
    • 0023200493 scopus 로고
    • Persistence of human milk proteins in the breast-fed infant
    • L.A. Davidson, and B. Lonnerdal Persistence of human milk proteins in the breast-fed infant Acta Paediatr Scand 76 1987 733 740 (Pubitemid 17154939)
    • (1987) Acta Paediatrica Scandinavica , vol.76 , Issue.5 , pp. 733-740
    • Davidson, L.A.1    Lonnerdal, B.2
  • 11
    • 0033788822 scopus 로고    scopus 로고
    • Lactoferrin upregulates the expression of CD4 antigen through the stimulation of the mitogen-activated protein kinase in the human lymphoblastic T Jurkat cell line
    • I. Dhennin-Duthille, M. Masson, E. Damiens, C. Fillebeen, G. Spik, and J. Mazurier Lactoferrin upregulates the expression of CD4 antigen through the stimulation of the mitogen-activated protein kinase in the human lymphoblastic T Jurkat cell line J Cell Biochem 79 2000 583 593
    • (2000) J Cell Biochem , vol.79 , pp. 583-593
    • Dhennin-Duthille, I.1    Masson, M.2    Damiens, E.3    Fillebeen, C.4    Spik, G.5    Mazurier, J.6
  • 12
    • 33746257209 scopus 로고    scopus 로고
    • The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism
    • DOI 10.1038/nrg1879, PII NRG1879
    • J.A. Engelman, J. Luo, and L.C. Cantley The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism Nat Rev Genet 7 2006 606 619 (Pubitemid 44100518)
    • (2006) Nature Reviews Genetics , vol.7 , Issue.8 , pp. 606-619
    • Engelman, J.A.1    Luo, J.2    Cantley, L.C.3
  • 13
    • 0026654558 scopus 로고
    • Regulation of brush-border enzyme activities and enterocyte migration rates in mouse small intestine
    • R.P. Ferraris, S.A. Villenas, and J. Diamond Regulation of brush-border enzyme activities and enterocyte migration rates in mouse small intestine Am J Physiol 262 1992 G1047 G1059
    • (1992) Am J Physiol , vol.262
    • Ferraris, R.P.1    Villenas, S.A.2    Diamond, J.3
  • 14
    • 73349115588 scopus 로고    scopus 로고
    • Integrin-linked kinase regulates migration and proliferation of human intestinal cells under a fibronectin-dependent mechanism
    • D. Gagne, J.F. Groulx, Y.D. Benoit, N. Basora, E. Herring, and P.H. Vachon Integrin-linked kinase regulates migration and proliferation of human intestinal cells under a fibronectin-dependent mechanism J Cell Physiol 222 2010 387 400
    • (2010) J Cell Physiol , vol.222 , pp. 387-400
    • Gagne, D.1    Groulx, J.F.2    Benoit, Y.D.3    Basora, N.4    Herring, E.5    Vachon, P.H.6
  • 15
    • 33644517238 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase controls early and late events in mammalian cell division
    • DOI 10.1038/sj.emboj.7600967, PII 7600967
    • Z. Garcia, A. Kumar, M. Marques, I. Cortes, and A.C. Carrera Phosphoinositide 3-kinase controls early and late events in mammalian cell division EMBO J 25 2006 655 661 (Pubitemid 43292428)
    • (2006) EMBO Journal , vol.25 , Issue.4 , pp. 655-661
    • Garcia, Z.1    Kumar, A.2    Marques, M.3    Cortes, I.4    Carrera, A.C.5
  • 16
    • 0035201179 scopus 로고    scopus 로고
    • Dexamethasone administration to newborn mice alters mucosal and muscular morphology in the ileum and modulates IGF-I localization
    • P.V. Gordon, W.A. Price, and A.D. Stiles Dexamethasone administration to newborn mice alters mucosal and muscular morphology in the ileum and modulates IGF-I localization Pediatr Res 49 2001 93 100 (Pubitemid 32015006)
    • (2001) Pediatric Research , vol.49 , Issue.1 , pp. 93-100
    • Gordon, P.V.1    Price, W.A.2    Stiles, A.D.3
  • 18
    • 33646550545 scopus 로고    scopus 로고
    • Lactoferrin potently inhibits osteoblast apoptosis, via an LRP1-independent pathway
    • DOI 10.1016/j.mce.2006.03.002, PII S0303720706001055
    • A. Grey, Q. Zhu, M. Watson, K. Callon, and J. Cornish Lactoferrin potently inhibits osteoblast apoptosis, via an LRP1-independent pathway Mol Cell Endocrinol 251 2006 96 102 (Pubitemid 43728834)
    • (2006) Molecular and Cellular Endocrinology , vol.251 , Issue.1-2 , pp. 96-102
    • Grey, A.1    Zhu, Q.2    Watson, M.3    Callon, K.4    Cornish, J.5
  • 21
    • 0026023387 scopus 로고
    • Origin of intact lactoferrin and its DNA-binding fragments found in the urine of human milk-fed preterm infants evaluation by stable isotopic enrichment
    • T.W. Hutchens, J.F. Henry, T.T. Yip, D.L. Hachey, R.J. Schanler, and K.J. Motil Origin of intact lactoferrin and its DNA-binding fragments found in the urine of human milk-fed preterm infants evaluation by stable isotopic enrichment Pediatr Res 29 1991 243 250
    • (1991) Pediatr Res , vol.29 , pp. 243-250
    • Hutchens, T.W.1    Henry, J.F.2    Yip, T.T.3    Hachey, D.L.4    Schanler, R.J.5    Motil, K.J.6
  • 22
    • 0032213139 scopus 로고    scopus 로고
    • Structure of human apolactoferrin at 2.0 A resolution. Refinement and analysis of ligand-induced conformational change
    • G.B. Jameson, B.F. Anderson, G.E. Norris, D.H. Thomas, and E.N. Baker Structure of human apolactoferrin at 2.0 A resolution. Refinement and analysis of ligand-induced conformational change Acta Crystallogr D Biol Crystallogr 54 1998 1319 1335
    • (1998) Acta Crystallogr D Biol Crystallogr , vol.54 , pp. 1319-1335
    • Jameson, G.B.1    Anderson, B.F.2    Norris, G.E.3    Thomas, D.H.4    Baker, E.N.5
  • 23
    • 80051937861 scopus 로고    scopus 로고
    • Apo- and holo-lactoferrin are both internalized by lactoferrin receptor via clathrin-mediated endocytosis but differentially affect ERK-signaling and cell proliferation in caco-2 cells
    • R. Jiang, V. Lopez, S.L. Kelleher, and B. Lonnerdal Apo- and holo-lactoferrin are both internalized by lactoferrin receptor via clathrin-mediated endocytosis but differentially affect ERK-signaling and cell proliferation in caco-2 cells J Cell Physiol 226 2011 3022 3031
    • (2011) J Cell Physiol , vol.226 , pp. 3022-3031
    • Jiang, R.1    Lopez, V.2    Kelleher, S.L.3    Lonnerdal, B.4
  • 25
    • 33745116879 scopus 로고    scopus 로고
    • A novel apoptosis cascade mediated by lysosomal lactoferrin and its participation in hepatocyte apoptosis induced by d-galactosamine
    • DOI 10.1016/j.febslet.2006.05.057, PII S0014579306006703
    • N. Katunuma, Q.T. Le, E. Murata, A. Matsui, E. Majima, and N. Ishimaru A novel apoptosis cascade mediated by lysosomal lactoferrin and its participation in hepatocyte apoptosis induced by d-galactosamine FEBS Lett 580 2006 3699 3705 (Pubitemid 43902806)
    • (2006) FEBS Letters , vol.580 , Issue.15 , pp. 3699-3705
    • Katunuma, N.1    Le, Q.T.2    Murata, E.3    Matsui, A.4    Majima, E.5    Ishimaru, N.6    Hayashi, Y.7    Ohashi, A.8
  • 27
    • 0029786329 scopus 로고    scopus 로고
    • Cyclin D1 expression is regulated positively by the p42/p44(MAPK) and negatively by the p38/HOG(MAPK) pathway
    • DOI 10.1074/jbc.271.34.20608
    • J.N. Lavoie, G. L'Allemain, A. Brunet, R. Muller, and J. Pouyssegur Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway J Biol Chem 271 1996 20608 20616 (Pubitemid 26281839)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.34 , pp. 20608-20616
    • Lavoie, J.N.1    L'Allemain, G.2    Brunei, A.3    Muller, R.4    Pouyssegur, J.5
  • 30
    • 0029130333 scopus 로고
    • Lactoferrin: Molecular structure and biological function
    • B. Lonnerdal, and S. Iyer Lactoferrin: molecular structure and biological function Annu Rev Nutr 15 1995 93 110
    • (1995) Annu Rev Nutr , vol.15 , pp. 93-110
    • Lonnerdal, B.1    Iyer, S.2
  • 31
    • 42549125136 scopus 로고    scopus 로고
    • Lactoferrin receptor mediates apo- but not holo-lactoferrin internalization via clathrin-mediated endocytosis in trophoblasts
    • DOI 10.1042/BJ20070393
    • V. Lopez, S.L. Kelleher, and B. Lonnerdal Lactoferrin receptor mediates apo- but not holo-lactoferrin internalization via clathrin-mediated endocytosis in trophoblasts Biochem J 441 2008 271 278 (Pubitemid 351580179)
    • (2008) Biochemical Journal , vol.411 , Issue.2 , pp. 271-278
    • Lopez, V.1    Kelleher, S.L.2    Lonnerdal, B.3
  • 32
    • 33748438863 scopus 로고    scopus 로고
    • Ontogenic changes in lactoferrin receptor and DMT1 in mouse small intestine: Implications for iron absorption during early life
    • DOI 10.1139/O06-059
    • V. Lopez, Y.A. Suzuki, and B. Lonnerdal Ontogenic changes in lactoferrin receptor and DMT1 in mouse small intestine: implications for iron absorption during early life Biochem Cell Biol 84 2006 337 344 (Pubitemid 44341308)
    • (2006) Biochemistry and Cell Biology , vol.84 , Issue.3 , pp. 337-344
    • Lopez, V.1    Suzuki, Y.A.2    Lonnerdal, B.3
  • 33
    • 79958026380 scopus 로고    scopus 로고
    • The Ras-ERK and PI3K-mTOR pathways: Cross-talk and compensation
    • M.C. Mendoza, E.E. Er, and J. Blenis The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation Trends Biochem Sci 36 2011 320 328
    • (2011) Trends Biochem Sci , vol.36 , pp. 320-328
    • Mendoza, M.C.1    Er, E.E.2    Blenis, J.3
  • 34
    • 0028025037 scopus 로고
    • Apical-to-basolateral transepithelial transport of human lactoferrin in the intestinal cell line HT-29cl.19A
    • T. Mikogami, M. Heyman, G. Spik, and J.F. Desjeux Apical-to-basolateral transepithelial transport of human lactoferrin in the intestinal cell line HT-29cl.19A Am J Physiol 267 1994 G308 G315
    • (1994) Am J Physiol , vol.267
    • Mikogami, T.1    Heyman, M.2    Spik, G.3    Desjeux, J.F.4
  • 38
    • 0023228506 scopus 로고
    • Human lactoferrin stimulates thymidine incorporation into DNA of rat crypt cells
    • B.L. Nichols, K.S. McKee, J.F. Henry, and M. Putman Human lactoferrin stimulates thymidine incorporation into DNA of rat crypt cells Pediatr Res 21 1987 563 567 (Pubitemid 17076188)
    • (1987) Pediatric Research , vol.21 , Issue.6 , pp. 563-567
    • Nichols, B.L.1    Mckee, K.S.2    Henry, J.F.3    Putman, M.4
  • 39
    • 0029003339 scopus 로고
    • Iron saturation alters the effect of lactoferrin on the proliferation and differentiation of human enterocytes (Caco-2 cells)
    • S. Oguchi, W.A. Walker, and I.R. Sanderson Iron saturation alters the effect of lactoferrin on the proliferation and differentiation of human enterocytes (Caco-2 cells) Biol Neonate 67 1995 330 339
    • (1995) Biol Neonate , vol.67 , pp. 330-339
    • Oguchi, S.1    Walker, W.A.2    Sanderson, I.R.3
  • 40
    • 0035834720 scopus 로고    scopus 로고
    • Human neutrophil lactoferrin trans-activates the matrix metalloproteinase 1 gene through stress-activated MAPK signaling modules
    • S.M. Oh, D.H. Hahm, I.H. Kim, and S.Y. Choi Human neutrophil lactoferrin trans-activates the matrix metalloproteinase 1 gene through stress-activated MAPK signaling modules J Biol Chem 276 2001 42575 42579
    • (2001) J Biol Chem , vol.276 , pp. 42575-42579
    • Oh, S.M.1    Hahm, D.H.2    Kim, I.H.3    Choi, S.Y.4
  • 41
    • 67349157318 scopus 로고    scopus 로고
    • Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche
    • A. Ootani, X. Li, E. Sangiorgi, Q.T. Ho, H. Ueno, and S. Toda Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche Nat Med 15 2009 701 706
    • (2009) Nat Med , vol.15 , pp. 701-706
    • Ootani, A.1    Li, X.2    Sangiorgi, E.3    Ho, Q.T.4    Ueno, H.5    Toda, S.6
  • 43
    • 73349095402 scopus 로고    scopus 로고
    • Thrombin stimulates RPE cell proliferation by promoting c-Fos-mediated cyclin D1 expression
    • A. Parrales, J.P. Palma-Nicolas, E. Lopez, and A.M. Lopez-Colome Thrombin stimulates RPE cell proliferation by promoting c-Fos-mediated cyclin D1 expression J Cell Physiol 222 2010 302 312
    • (2010) J Cell Physiol , vol.222 , pp. 302-312
    • Parrales, A.1    Palma-Nicolas, J.P.2    Lopez, E.3    Lopez-Colome, A.M.4
  • 44
    • 0034997845 scopus 로고    scopus 로고
    • Mitogen-activated protein (MAP) kinase pathways: Regulation and physiological functions
    • DOI 10.1210/er.22.2.153
    • G. Pearson, F. Robinson, T. Beers Gibson, B.E. Xu, M. Karandikar, and K. Berman Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions Endocr Rev 22 2001 153 183 (Pubitemid 32458157)
    • (2001) Endocrine Reviews , vol.22 , Issue.2 , pp. 153-183
    • Pearson, G.1    Robinson, F.2    Gibson, T.B.3    Xu, B.-E.4    Karandikar, M.5    Berman, K.6    Cobb, M.H.7
  • 45
    • 34248597065 scopus 로고    scopus 로고
    • Differential regulation and properties of MAPKs
    • DOI 10.1038/sj.onc.1210392, PII 1210392
    • M. Raman, W. Chen, and M.H. Cobb Differential regulation and properties of MAPKs Oncogene 26 2007 3100 3112 (Pubitemid 46763006)
    • (2007) Oncogene , vol.26 , Issue.22 , pp. 3100-3112
    • Raman, M.1    Chen, W.2    Cobb, M.H.3
  • 46
    • 20044371666 scopus 로고    scopus 로고
    • The Caco-2 cell line as a model of the intestinal barrier: Influence of cell and culture-related factors on Caco-2 cell functional characteristics
    • DOI 10.1007/s10565-005-0085-6
    • Y. Sambuy, I. De Angelis, G. Ranaldi, M.L. Scarino, A. Stammati, and F. Zucco The Caco-2 cell line as a model of the intestinal barrier: influence of cell and culture-related factors on Caco-2 cell functional characteristics Cell Biol Toxicol 21 2005 1 26 (Pubitemid 40767684)
    • (2005) Cell Biology and Toxicology , vol.21 , Issue.1 , pp. 1-26
    • Sambuy, Y.1    De Angelis, I.2    Ranaldi, G.3    Scarino, M.L.4    Stammati, A.5    Zucco, F.6
  • 47
    • 0023780022 scopus 로고
    • Development of the pattern of cell renewal in the crypt-villus unit of chimaeric mouse small intestine
    • G.H. Schmidt, D.J. Winton, and B.A. Ponder Development of the pattern of cell renewal in the crypt-villus unit of chimaeric mouse small intestine Development 103 1988 785 790
    • (1988) Development , vol.103 , pp. 785-790
    • Schmidt, G.H.1    Winton, D.J.2    Ponder, B.A.3
  • 48
    • 33745307617 scopus 로고    scopus 로고
    • Ras, PI(3)K and mTOR signalling controls tumour cell growth
    • DOI 10.1038/nature04869, PII NATURE04869
    • R.J. Shaw, and L.C. Cantley Ras, PI(3)K and mTOR signalling controls tumour cell growth Nature 441 2006 424 430 (Pubitemid 44050136)
    • (2006) Nature , vol.441 , Issue.7092 , pp. 424-430
    • Shaw, R.J.1    Cantley, L.C.2
  • 49
    • 8644219655 scopus 로고    scopus 로고
    • Living with or without cyclins and cyclin-dependent kinases
    • DOI 10.1101/gad.1256504
    • C.J. Sherr, and J.M. Roberts Living with or without cyclins and cyclin-dependent kinases Genes Dev 18 2004 2699 2711 (Pubitemid 39507762)
    • (2004) Genes and Development , vol.18 , Issue.22 , pp. 2699-2711
    • Sherr, C.J.1    Roberts, J.M.2
  • 50
    • 3342880250 scopus 로고    scopus 로고
    • Baculovirus expression of mouse lactoferrin receptor and tissue distribution in the mouse
    • DOI 10.1023/B:BIOM.0000027709.42733.e4
    • Y.A. Suzuki, and B. Lonnerdal Baculovirus expression of mouse lactoferrin receptor and tissue distribution in the mouse Biometals 17 2004 301 309 (Pubitemid 38987154)
    • (2004) BioMetals , vol.17 , Issue.3 , pp. 301-309
    • Suzuki, Y.A.1    Lonnerdal, B.2
  • 51
    • 28344453346 scopus 로고    scopus 로고
    • Mammalian lactoferrin receptors: Structure and function
    • DOI 10.1007/s00018-005-5371-1
    • Y.A. Suzuki, V. Lopez, and B. Lonnerdal Mammalian lactoferrin receptors: structure and function Cell Mol Life Sci 62 2005 2560 2575 (Pubitemid 41721230)
    • (2005) Cellular and Molecular Life Sciences , vol.62 , Issue.22 , pp. 2560-2575
    • Suzuki, Y.A.1    Lopez, V.2    Lonnerdal, B.3
  • 52
    • 0035951070 scopus 로고    scopus 로고
    • Molecular cloning and functional expression of a human intestinal lactoferrin receptor
    • DOI 10.1021/bi0155899
    • Y.A. Suzuki, K. Shin, and B. Lonnerdal Molecular cloning and functional expression of a human intestinal lactoferrin receptor Biochemistry 40 2001 15771 15779 (Pubitemid 34015206)
    • (2001) Biochemistry , vol.40 , Issue.51 , pp. 15771-15779
    • Suzuki, Y.A.1    Shin, K.2    Lonnerdal, B.3
  • 53
    • 34248572839 scopus 로고    scopus 로고
    • MAP kinases and the control of nuclear events
    • DOI 10.1038/sj.onc.1210415, PII 1210415
    • A.G. Turjanski, J.P. Vaque, and J.S. Gutkind MAP kinases and the control of nuclear events Oncogene 26 2007 3240 3253 (Pubitemid 46763018)
    • (2007) Oncogene , vol.26 , Issue.22 , pp. 3240-3253
    • Turjanski, A.G.1    Vaque, J.P.2    Gutkind, J.S.3
  • 54
    • 0030664951 scopus 로고    scopus 로고
    • 5 of human lactoferrin is essential for binding to heparin, bacterial lipopolysaccharide, human lysozyme and DNA
    • P.H. van Berkel, M.E. Geerts, H.A. van Veen, M. Mericskay, H.A. de Boer, and J.H. Nuijens N-terminal stretch Arg2 Arg3, Arg4 and Arg5 of human lactoferrin is essential for binding to heparin, bacterial lipopolysaccharide, human lysozyme and DNA Biochem J 328 Pt 1 1997 145 151 (Pubitemid 27499451)
    • (1997) Biochemical Journal , vol.328 , Issue.1 , pp. 145-151
    • Van Berkel, P.H.C.1    Geerts, M.E.J.2    Van Veen, H.A.3    Mericskay, M.4    De Boer, H.A.5    Nuijens, J.H.6
  • 56
    • 39749195406 scopus 로고    scopus 로고
    • Cip1
    • DOI 10.1042/BJ20070781
    • C. Yang, E.A. Klein, R.K. Assoian, and M.G. Kazanietz Heregulin beta1 promotes breast cancer cell proliferation through Rac/ERK-dependent induction of cyclin D1 and p21Cip1 Biochem J 410 2008 167 175 (Pubitemid 351300336)
    • (2008) Biochemical Journal , vol.410 , Issue.1 , pp. 167-175
    • Yang, C.1    Klein, E.A.2    Assoian, R.K.3    Kazanietz, M.G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.