메뉴 건너뛰기




Volumn 75, Issue 1, 2012, Pages 15-23

Combined α-tocopherol and ascorbic acid protects against smoke-induced lung squamous metaplasia in ferrets

Author keywords

Antioxidants; Cigarette smoke; Cyclin D1; Lung carcinogenesis; Retinoic acid

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; CYCLIN D1; MALONALDEHYDE; PEROXIDASE; PROTEIN C JUN; RETINOIC ACID; RETINOIC ACID RECEPTOR ALPHA; RETINOIC ACID RECEPTOR BETA; RETINOL; RETINOL PALMITATE; TOBACCO SMOKE;

EID: 83555166283     PISSN: 01695002     EISSN: 18728332     Source Type: Journal    
DOI: 10.1016/j.lungcan.2011.05.017     Document Type: Article
Times cited : (15)

References (37)
  • 2
    • 0010607277 scopus 로고    scopus 로고
    • The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. The Alpha-Tocopherol, Beta Carotene Cancer Prevention Study Group.
    • N Engl J Med 1994;330:1029-35.
    • The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. The Alpha-Tocopherol, Beta Carotene Cancer Prevention Study Group. N Engl J Med 1994;330:1029-35.
  • 3
    • 10344238570 scopus 로고    scopus 로고
    • Alpha-tocopherol and beta-carotene supplements and lung cancer incidence in the alpha-tocopherol, beta-carotene cancer prevention study: effects of base-line characteristics and study compliance
    • Albanes D., Heinonen O.P., Taylor P.R., Virtamo J., Edwards B.K., Rautalahti M., et al. Alpha-tocopherol and beta-carotene supplements and lung cancer incidence in the alpha-tocopherol, beta-carotene cancer prevention study: effects of base-line characteristics and study compliance. J Natl Cancer Inst 1996, 88:1560-1570.
    • (1996) J Natl Cancer Inst , vol.88 , pp. 1560-1570
    • Albanes, D.1    Heinonen, O.P.2    Taylor, P.R.3    Virtamo, J.4    Edwards, B.K.5    Rautalahti, M.6
  • 4
    • 0038692733 scopus 로고    scopus 로고
    • Risk factors for lung cancer and for intervention effects in CARET, the Beta-Carotene and Retinol Efficacy Trial
    • Omenn G.S., Goodman G.E., Thornquist M.D., Balmes J., Cullen M.R., Glass A., et al. Risk factors for lung cancer and for intervention effects in CARET, the Beta-Carotene and Retinol Efficacy Trial. J Natl Cancer Inst 1996, 88:1550-1559.
    • (1996) J Natl Cancer Inst , vol.88 , pp. 1550-1559
    • Omenn, G.S.1    Goodman, G.E.2    Thornquist, M.D.3    Balmes, J.4    Cullen, M.R.5    Glass, A.6
  • 5
    • 9244262406 scopus 로고    scopus 로고
    • Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease
    • Omenn G.S., Goodman G.E., Thornquist M.D., Balmes J., Cullen M.R., Glass A., et al. Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease. N Engl J Med 1996, 334:1150-1155.
    • (1996) N Engl J Med , vol.334 , pp. 1150-1155
    • Omenn, G.S.1    Goodman, G.E.2    Thornquist, M.D.3    Balmes, J.4    Cullen, M.R.5    Glass, A.6
  • 6
    • 0033528079 scopus 로고    scopus 로고
    • Retinoid signaling and activator protein-1 expression in ferrets given beta-carotene supplements and exposed to tobacco smoke
    • Wang X.D., Liu C., Bronson R.T., Smith D.E., Krinsky N.I., Russell M. Retinoid signaling and activator protein-1 expression in ferrets given beta-carotene supplements and exposed to tobacco smoke. J Natl Cancer Inst 1999, 91:60-66.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 60-66
    • Wang, X.D.1    Liu, C.2    Bronson, R.T.3    Smith, D.E.4    Krinsky, N.I.5    Russell, M.6
  • 7
    • 4744341925 scopus 로고    scopus 로고
    • Low dose beta-carotene supplementation of ferrets attenuates smoke-induced lung phosphorylation of JNK, p38 MAPK, and p53 proteins
    • Liu C., Russell R.M., Wang X.D. Low dose beta-carotene supplementation of ferrets attenuates smoke-induced lung phosphorylation of JNK, p38 MAPK, and p53 proteins. J Nutr 2004, 134:2705-2710.
    • (2004) J Nutr , vol.134 , pp. 2705-2710
    • Liu, C.1    Russell, R.M.2    Wang, X.D.3
  • 9
    • 0034521543 scopus 로고    scopus 로고
    • Effects of physiological versus pharmacological beta-carotene supplementation on cell proliferation and histopathological changes in the lungs of cigarette smoke-exposed ferrets
    • Liu C., Wang X.D., Bronson R.T., Smith D.E., Krinsky N.I., Russell R.M. Effects of physiological versus pharmacological beta-carotene supplementation on cell proliferation and histopathological changes in the lungs of cigarette smoke-exposed ferrets. Carcinogenesis 2000, 21:2245-2253.
    • (2000) Carcinogenesis , vol.21 , pp. 2245-2253
    • Liu, C.1    Wang, X.D.2    Bronson, R.T.3    Smith, D.E.4    Krinsky, N.I.5    Russell, R.M.6
  • 10
    • 33745728937 scopus 로고    scopus 로고
    • Combined antioxidant (beta-carotene, alpha-tocopherol and ascorbic acid) supplementation increases the levels of lung retinoic acid and inhibits the activation of mitogen-activated protein kinase in the ferret lung cancer model
    • Kim Y., Chongviriyaphan N., Liu C., Russell R.M., Wang X.D. Combined antioxidant (beta-carotene, alpha-tocopherol and ascorbic acid) supplementation increases the levels of lung retinoic acid and inhibits the activation of mitogen-activated protein kinase in the ferret lung cancer model. Carcinogenesis 2006, 27:1410-1419.
    • (2006) Carcinogenesis , vol.27 , pp. 1410-1419
    • Kim, Y.1    Chongviriyaphan, N.2    Liu, C.3    Russell, R.M.4    Wang, X.D.5
  • 11
    • 0035162101 scopus 로고    scopus 로고
    • Ethanol enhances retinoic acid metabolism into polar metabolites in rat liver via induction of cytochrome P4502E1
    • Liu C., Russell R.M., Seitz H.K., Wang X.D. Ethanol enhances retinoic acid metabolism into polar metabolites in rat liver via induction of cytochrome P4502E1. Gastroenterology 2001, 120:179-189.
    • (2001) Gastroenterology , vol.120 , pp. 179-189
    • Liu, C.1    Russell, R.M.2    Seitz, H.K.3    Wang, X.D.4
  • 12
    • 0037228085 scopus 로고    scopus 로고
    • Exposing ferrets to cigarette smoke and a pharmacological dose of beta-carotene supplementation enhance in vitro retinoic acid catabolism in lungs via induction of cytochrome P450 enzymes
    • Liu C., Russell R.M., Wang X.D. Exposing ferrets to cigarette smoke and a pharmacological dose of beta-carotene supplementation enhance in vitro retinoic acid catabolism in lungs via induction of cytochrome P450 enzymes. J Nutr 2003, 133:173-179.
    • (2003) J Nutr , vol.133 , pp. 173-179
    • Liu, C.1    Russell, R.M.2    Wang, X.D.3
  • 13
    • 0030906015 scopus 로고    scopus 로고
    • Vitamin E supplementation and in vivo immune response in healthy elderly subjects. A randomized controlled trial
    • Meydani S.N., Meydani M., Blumberg J.B., Leka L.S., Siber G., Loszewski R., et al. Vitamin E supplementation and in vivo immune response in healthy elderly subjects. A randomized controlled trial. JAMA 1997, 277:1380-1386.
    • (1997) JAMA , vol.277 , pp. 1380-1386
    • Meydani, S.N.1    Meydani, M.2    Blumberg, J.B.3    Leka, L.S.4    Siber, G.5    Loszewski, R.6
  • 14
    • 0028339787 scopus 로고
    • NADPH-initiated cytochrome P450-mediated free metal ion-independent oxidative damage of microsomal proteins. Exclusive prevention by ascorbic acid
    • Mukhopadhyay C.K., Chatterjee I.B. NADPH-initiated cytochrome P450-mediated free metal ion-independent oxidative damage of microsomal proteins. Exclusive prevention by ascorbic acid. J Biol Chem 1994, 269:13390-13397.
    • (1994) J Biol Chem , vol.269 , pp. 13390-13397
    • Mukhopadhyay, C.K.1    Chatterjee, I.B.2
  • 15
    • 33845951110 scopus 로고    scopus 로고
    • Cyclin D1 in non-small cell lung cancer: a key driver of malignant transformation
    • Gautschi O., Ratschiller D., Gugger M., Betticher D.C., Heighway J. Cyclin D1 in non-small cell lung cancer: a key driver of malignant transformation. Lung Cancer 2007, 55:1-14.
    • (2007) Lung Cancer , vol.55 , pp. 1-14
    • Gautschi, O.1    Ratschiller, D.2    Gugger, M.3    Betticher, D.C.4    Heighway, J.5
  • 16
    • 0033111210 scopus 로고    scopus 로고
    • Prognostic role of cyclin D1 in lung cancer. Relationship to proliferating cell nuclear antigen
    • Caputi M., Groeger A.M., Esposito V., Dean C., De Luca A., Pacilio C., et al. Prognostic role of cyclin D1 in lung cancer. Relationship to proliferating cell nuclear antigen. Am J Respir Cell Mol Biol 1999, 20:746-750.
    • (1999) Am J Respir Cell Mol Biol , vol.20 , pp. 746-750
    • Caputi, M.1    Groeger, A.M.2    Esposito, V.3    Dean, C.4    De Luca, A.5    Pacilio, C.6
  • 18
    • 0023005882 scopus 로고
    • Regulation of differentiation of airway epithelial cells by retinoids
    • Jetten A.M., Rearick J.I., Smits H.L. Regulation of differentiation of airway epithelial cells by retinoids. Biochem Soc Trans 1986, 14:930-933.
    • (1986) Biochem Soc Trans , vol.14 , pp. 930-933
    • Jetten, A.M.1    Rearick, J.I.2    Smits, H.L.3
  • 19
    • 0024405690 scopus 로고
    • Effects of bryostatins and retinoic acid on phorbol ester- and diacylglycerol-induced squamous differentiation in human tracheobronchial epithelial cells
    • Jetten A.M., George M.A., Pettit G.R., Rearick J.I. Effects of bryostatins and retinoic acid on phorbol ester- and diacylglycerol-induced squamous differentiation in human tracheobronchial epithelial cells. Cancer Res 1989, 49:3990-3995.
    • (1989) Cancer Res , vol.49 , pp. 3990-3995
    • Jetten, A.M.1    George, M.A.2    Pettit, G.R.3    Rearick, J.I.4
  • 20
    • 0027411409 scopus 로고
    • Regulation of transglutaminase type I expression in squamous differentiating rabbit tracheal epithelial cells and human epidermal keratinocytes: effects of retinoic acid and phorbol esters
    • Saunders N.A., Bernacki S.H., Vollberg T.M., Jetten A.M. Regulation of transglutaminase type I expression in squamous differentiating rabbit tracheal epithelial cells and human epidermal keratinocytes: effects of retinoic acid and phorbol esters. Mol Endocrinol 1993, 7:387-398.
    • (1993) Mol Endocrinol , vol.7 , pp. 387-398
    • Saunders, N.A.1    Bernacki, S.H.2    Vollberg, T.M.3    Jetten, A.M.4
  • 21
    • 33847689364 scopus 로고    scopus 로고
    • Inhibition of lung carcinogenesis by 1alpha, 25-dihydroxyvitamin D3 and 9-cis retinoic acid in the A/J mouse model: evidence of retinoid mitigation of vitamin D toxicity
    • Mernitz H., Smith D.E., Wood R.J., Russell R.M., Wang X.D. Inhibition of lung carcinogenesis by 1alpha, 25-dihydroxyvitamin D3 and 9-cis retinoic acid in the A/J mouse model: evidence of retinoid mitigation of vitamin D toxicity. Int J Cancer 2007, 120:1402-1409.
    • (2007) Int J Cancer , vol.120 , pp. 1402-1409
    • Mernitz, H.1    Smith, D.E.2    Wood, R.J.3    Russell, R.M.4    Wang, X.D.5
  • 22
    • 33749236979 scopus 로고    scopus 로고
    • 9-cis-Retinoic acid inhibition of lung carcinogenesis in the A/J mouse model is accompanied by increased expression of RAR-beta but no change in cyclooxygenase-2
    • Mernitz H., Smith D.E., Zhu A.X., Wang X.D. 9-cis-Retinoic acid inhibition of lung carcinogenesis in the A/J mouse model is accompanied by increased expression of RAR-beta but no change in cyclooxygenase-2. Cancer Lett 2006, 244:101-108.
    • (2006) Cancer Lett , vol.244 , pp. 101-108
    • Mernitz, H.1    Smith, D.E.2    Zhu, A.X.3    Wang, X.D.4
  • 24
    • 0032549649 scopus 로고    scopus 로고
    • All-trans-retinoic acid inhibits Jun N-terminal kinase-dependent signaling pathways
    • Lee H.Y., Walsh G.L., Dawson M.I., Hong W.K., Kurie J.M. All-trans-retinoic acid inhibits Jun N-terminal kinase-dependent signaling pathways. J Biol Chem 1998, 273:7066-7071.
    • (1998) J Biol Chem , vol.273 , pp. 7066-7071
    • Lee, H.Y.1    Walsh, G.L.2    Dawson, M.I.3    Hong, W.K.4    Kurie, J.M.5
  • 25
    • 0032980121 scopus 로고    scopus 로고
    • All-trans-retinoic acid inhibits Jun N-terminal kinase by increasing dual-specificity phosphatase activity
    • Lee H.Y., Sueoka N., Hong W.K., Mangelsdorf D.J., Claret F.X., Kurie J.M. All-trans-retinoic acid inhibits Jun N-terminal kinase by increasing dual-specificity phosphatase activity. Mol Cell Biol 1999, 19:1973-1980.
    • (1999) Mol Cell Biol , vol.19 , pp. 1973-1980
    • Lee, H.Y.1    Sueoka, N.2    Hong, W.K.3    Mangelsdorf, D.J.4    Claret, F.X.5    Kurie, J.M.6
  • 27
    • 0037099516 scopus 로고    scopus 로고
    • Loss of retinoic acid receptor beta gene expression is linked to aberrant histone H3 acetylation in lung cancer cell lines
    • Suh Y.A., Lee H.Y., Virmani A., Wong J., Mann K.K., Miller W.H., et al. Loss of retinoic acid receptor beta gene expression is linked to aberrant histone H3 acetylation in lung cancer cell lines. Cancer Res 2002, 62:3945-3949.
    • (2002) Cancer Res , vol.62 , pp. 3945-3949
    • Suh, Y.A.1    Lee, H.Y.2    Virmani, A.3    Wong, J.4    Mann, K.K.5    Miller, W.H.6
  • 28
    • 0142053910 scopus 로고    scopus 로고
    • Aberrant methylation of multiple genes in the upper aerodigestive tract epithelium of heavy smokers
    • Zochbauer-Muller S., Lam S., Toyooka S., Virmani A.K., Toyooka K.O., Seidl S., et al. Aberrant methylation of multiple genes in the upper aerodigestive tract epithelium of heavy smokers. Int J Cancer 2003, 107:612-616.
    • (2003) Int J Cancer , vol.107 , pp. 612-616
    • Zochbauer-Muller, S.1    Lam, S.2    Toyooka, S.3    Virmani, A.K.4    Toyooka, K.O.5    Seidl, S.6
  • 29
    • 20144388725 scopus 로고    scopus 로고
    • Retinoic acid targets DNA-methyltransferases and histone deacetylases during APL blast differentiation in vitro and in vivo
    • Fazi F., Travaglini L., Carotti D., Palitti F., Diverio D., Alcalay M., et al. Retinoic acid targets DNA-methyltransferases and histone deacetylases during APL blast differentiation in vitro and in vivo. Oncogene 2005, 24:1820-1830.
    • (2005) Oncogene , vol.24 , pp. 1820-1830
    • Fazi, F.1    Travaglini, L.2    Carotti, D.3    Palitti, F.4    Diverio, D.5    Alcalay, M.6
  • 30
    • 0032820358 scopus 로고    scopus 로고
    • Vitamin E regulates mitochondrial hydrogen peroxide generation
    • Chow C.K., Ibrahim W., Wei Z., Chan A.C. Vitamin E regulates mitochondrial hydrogen peroxide generation. Free Radic Biol Med 1999, 27:580-587.
    • (1999) Free Radic Biol Med , vol.27 , pp. 580-587
    • Chow, C.K.1    Ibrahim, W.2    Wei, Z.3    Chan, A.C.4
  • 31
    • 0029829954 scopus 로고    scopus 로고
    • Induction of c-jun protooncogene expression by hydrogen peroxide through hydroxyl radical generation and p60SRC tyrosine kinase activation
    • Lee S.F., Huang Y.T., Wu W.S., Lin J.K. Induction of c-jun protooncogene expression by hydrogen peroxide through hydroxyl radical generation and p60SRC tyrosine kinase activation. Free Radic Biol Med 1996, 21:437-448.
    • (1996) Free Radic Biol Med , vol.21 , pp. 437-448
    • Lee, S.F.1    Huang, Y.T.2    Wu, W.S.3    Lin, J.K.4
  • 32
    • 0029984062 scopus 로고    scopus 로고
    • Antioxidant and redox regulation of gene transcription
    • Sen C.K., Packer L. Antioxidant and redox regulation of gene transcription. FASEB J 1996, 10:709-720.
    • (1996) FASEB J , vol.10 , pp. 709-720
    • Sen, C.K.1    Packer, L.2
  • 33
    • 0032126403 scopus 로고    scopus 로고
    • Protein-PCNA interactions: a DNA-scanning mechanism?
    • Kelman Z., Hurwitz J. Protein-PCNA interactions: a DNA-scanning mechanism?. Trends Biochem Sci 1998, 23:236-238.
    • (1998) Trends Biochem Sci , vol.23 , pp. 236-238
    • Kelman, Z.1    Hurwitz, J.2
  • 35
    • 0033746230 scopus 로고    scopus 로고
    • Inhibits cell proliferation and the activation of extracellular signal-regulated kinase during the promotion phase of lung tumorigenesis irrespective of antioxidative effect
    • Yano T., Yajima S., Hagiwara K., Kumadaki I., Yano Y., Otani S., et al. inhibits cell proliferation and the activation of extracellular signal-regulated kinase during the promotion phase of lung tumorigenesis irrespective of antioxidative effect. Carcinogenesis 2000, 21:2129-2133.
    • (2000) Carcinogenesis , vol.21 , pp. 2129-2133
    • Yano, T.1    Yajima, S.2    Hagiwara, K.3    Kumadaki, I.4    Yano, Y.5    Otani, S.6
  • 36
    • 0031044561 scopus 로고    scopus 로고
    • MEKKs, GCKs, MLKs, PAKs, TAKs, and tpls: upstream regulators of the c-Jun amino-terminal kinases?
    • Fanger G.R., Gerwins P., Widmann C., Jarpe M.B., Johnson G.L. MEKKs, GCKs, MLKs, PAKs, TAKs, and tpls: upstream regulators of the c-Jun amino-terminal kinases?. Curr Opin Genet Dev 1997, 7:67-74.
    • (1997) Curr Opin Genet Dev , vol.7 , pp. 67-74
    • Fanger, G.R.1    Gerwins, P.2    Widmann, C.3    Jarpe, M.B.4    Johnson, G.L.5
  • 37
    • 0031600501 scopus 로고    scopus 로고
    • Growth factors and mitogen-activated protein kinases
    • Force T., Bonventre J.V. Growth factors and mitogen-activated protein kinases. Hypertension 1998, 31:152-161.
    • (1998) Hypertension , vol.31 , pp. 152-161
    • Force, T.1    Bonventre, J.V.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.