NFBD1/MDC1 is a protein of oncogenic potential in human cervical cancer

Molecular and Cellular Biochemistry

Volumn 359, Issue 1-2, 2012, Pages 333-346

  Yuan, Chengfu ^a   Bu, Youquan ^a   Wang, Changdong ^a   Yi, Faping ^a   Yang, Zhengmei ^a   Huang, Xiuning ^a   Cheng, Li ^a   Liu, Geli ^a   Wang, Yong ^a   Song, Fangzhou ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Cell growth; Cervical cancer; NFBD1; Retrovirus

Indexed keywords

CASPASE 3; CASPASE 9; CYCLIN B1; CYCLIN DEPENDENT KINASE 2; CYTOCHROME C; DOXORUBICIN; MDC1 PROTEIN; MESSENGER RNA; NFBD1 PROTEIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN NOXA; PUMA PROTEIN; SHORT HAIRPIN RNA; TUMOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CANCER TISSUE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL FUNCTION; CELL GROWTH; CELLULAR DISTRIBUTION; CHEMOSENSITIVITY; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GROWTH INHIBITION; HELA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; RETROVIRUS; RNA INTERFERENCE; UTERINE CERVIX CANCER; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; DOXORUBICIN; FEMALE; GENE KNOCKDOWN TECHNIQUES; HUMANS; MICE; MICE, NUDE; NUCLEAR PROTEINS; ONCOGENE PROTEINS; TRANS-ACTIVATORS; UTERINE CERVICAL NEOPLASMS;

MUS MUSCULUS;

EID: 83555166034     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-011-1027-7     Document Type: Article

References (20)

1. A Dueñas-González M Lizano M Candelaria L Cetina C Arce E Cervera 2005 Epigenetics of cervical cancer. An overview and therapeutic perspectives Mol Cancer 4 38 16248899 10.1186/1476-4598-4-38 (Pubitemid 41631192)
2. Z Yang Y Bu C Wang G Liu F Song 2010 Growth inhibition, morphology change, and cell cycle alterations in NFBD1-depleted human esophageal cancer cells Mol Cell Biochem 342 1 6 20364298 10.1007/s11010-010-0460-3 1:CAS:528:DC%2BC3cXhtVaqtLvJ
3. YL Shang AJ Bodero PL Chen 2003 NFBD1, a novel nuclear protein with signature motifs of FHA and BRCT, and an internal 41-amino acid repeat sequence, is an early participant in DNA damage response J Biol Chem 278 6323 6329 12475977 10.1074/jbc.M210749200 1:CAS:528:DC%2BD3sXht1ejsro%3D (Pubitemid 36800890)
4. GS Stewart B Wang CR Bignell AM Taylor SJ Elledge 2003 MDC1 is a mediator of the mammalian DNA damage checkpoint Nature 421 961 966 12607005 10.1038/nature01446 1:CAS:528:DC%2BD3sXhsVKgtbo%3D (Pubitemid 36288029)
5. Y Bu Y Suenaga S Ono T Koda F Song A Nakagawara T Ozaki 2008 Sp1-mediated transcriptional regulation of NFBD1/MDC1 plays a critical role in DNA damage response pathway Genes Cells 13 53 66 18173747 10.1111/j.1365-2443.2007.01144.x 1:CAS:528:DC%2BD1cXhsVahtLw%3D
6. T Ozaki T Nagase S Ichimiya N Seki M Ohiri N Nomura N Takada S Sakiyama BL Weber A Nakagawara 2000 NFBD1/KIAA0170 is a novel nuclear transcriptional transactivator with BRCT domain DNA Cell Biol 19 475 485 10975465 10.1089/10445490050128403 1:CAS:528:DC%2BD3cXmtFyhu7g%3D (Pubitemid 32186442)
7. Z Lou K Minter-Dykhouse S Franco M Gostissa MA Rivera A Celeste JP Manis J van Deursen A Nussenzweig TT Paull FW Alt J Chen 2006 MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals Mol Cell 21 187 200 16427009 10.1016/j.molcel.2005.11.025 1:CAS:528:DC%2BD28Xht12rs7s%3D (Pubitemid 43099935)
8. C Yuan C Wang Y Bu T Xiang X Huang Z Wang F Yi G Ren G Liu F Song 2010 Antioxidative and immunoprotective effects of Pyracantha fortuneana (Maxim.) Li polysaccharides in mice Immunol Lett 133 14 18 20403383 10.1016/j.imlet.2010.04. 004 1:CAS:528:DC%2BC3cXhtVKitrnI
9. R Ralhan LV Desouza A Matta S Chandra Tripathi S Ghanny S Datta Gupta S Bahadur KW Siu 2008 Discovery and verification of head-and-neck cancer biomarkers by differential protein expression analysis using iTRAQ labeling, multidimensional liquid chromatography, and tandem mass spectrometry Mol Cell Proteomics 7 1162 1173 18339795 10.1074/mcp.M700500-MCP200 1:CAS:528: DC%2BD1cXns1yntro%3D (Pubitemid 351943962)
10. K Takara M Fujita M Matsubara T Minegaki N Kitada N Ohnishi T Yokoyama 2007 Effects of propolis extract on sensitivity to chemotherapeutic agents in HeLa and resistant sublines Phytother Res 21 841 846 17486684 10.1002/ptr.2165 1:CAS:528:DC%2BD2sXhtFKgurnJ (Pubitemid 47401853)
11. D Tedesco J Zhang L Trinh G Lalehzadeh R Meisner KD Yamaguchi DL Ruderman H Dinter DA Zajchowski 2007 The ubiquitin-conjugating enzyme E2-EPF is overexpressed in primary breast cancer and modulates sensitivity to topoisomerase II inhibition Neoplasia 9 601 613 17710163 10.1593/neo.07385 1:CAS:528:DC%2BD2sXptlKruro%3D (Pubitemid 47121834)
12. SW Ha YJ Kim W Kim CS Lee 2009 Antitumor effects of camptothecin combined with conventional anticancer drugs on the cervical and uterine squamous cell carcinoma cell line SiHa Korean J Physiol Pharmacol 13 115 121 19885006 10.4196/kjpp.2009.13.2.115 1:CAS:528:DC%2BD1MXmtlagtL0%3D
13. CS Lee YJ Kim MS Lee ES Han SJ Lee 2008 18 beta-Glycyrrhetinic acid induces apoptotic cell death in SiHa cells and exhibits a synergistic effect against antibiotic anti-cancer drug toxicity Life Sci 83 481 489 18721818 10.1016/j.lfs.2008.07.014 1:CAS:528:DC%2BD1cXhtFekt7jE
14. PY Yeh SE Chuang KH Yeh YC Song AL Cheng 2003 Involvement of nuclear transcription factor-kappa B in low-dose doxorubicin-induced drug resistance of cervical carcinoma cells Biochem Pharmacol 66 25 33 12818362 10.1016/S0006-2952(03)00250-8 1:CAS:528:DC%2BD3sXks1WktL4%3D (Pubitemid 36724896)
15. J Bartek J Lukas 2007 DNA damage checkpoints: from initiation to recovery or adaptation Curr Opin Cell Biol 19 238 245 17303408 10.1016/j.ceb.2007.02.009 1:CAS:528:DC%2BD2sXjt1Sksrg%3D (Pubitemid 46386406)
16. MB Kastan J Bartek 2004 Cell-cycle checkpoints and cancer Nature 432 316 323 15549093 10.1038/nature03097 1:CAS:528:DC%2BD2cXpvVCjtLo%3D (Pubitemid 39551659)
17. J Bartkova Z Horejsí K Koed A Krämer F Tort K Zieger P Guldberg M Sehested JM Nesland C Lukas T Ørntoft J Lukas J Bartek 2005 DNA damage response as a candidate anticancer barrier in early human tumorigenesis Nature 434 864 870 15829956 10.1038/nature03482 1:CAS:528:DC%2BD2MXjtFOms7k%3D (Pubitemid 40558993)
18. VG Gorgoulis LV Vassiliou P Karakaidos P Zacharatos A Kotsinas T Liloglou M Venere RA Ditullio Jr NG Kastrinakis B Levy D Kletsas A Yoneta M Herlyn C Kittas TD Halazonetis 2005 Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions Nature 434 907 913 15829965 10.1038/nature03485 1:CAS:528:DC%2BD2MXjtFOms7Y%3D (Pubitemid 40559004)
19. A Fire S Xu MK Montgomery SA Kostas SE Driver CC Mello 1998 Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans Nature 391 806 811 9486653 10.1038/35888 1:CAS:528:DyaK1cXhtlCju74%3D (Pubitemid 28099681)
20. J Bartkova Z Horejsí M Sehested JM Nesland E Rajpert-De Meyts NE Skakkebaek M Stucki S Jackson J Lukas J Bartek 2007 DNA damage response mediators MDC1 and 53BP1: constitutive activation and aberrant loss in breast and lung cancer, but not in testicular germ cell tumours Oncogene 26 7414 7422 17546051 10.1038/sj.onc.1210553 1:CAS:528:DC%2BD2sXhtlCrsLfM (Pubitemid 350158716)