Design, synthesis, preliminary pharmacological evaluation, and docking studies of pyrazoline derivatives

Chemical Papers

Volumn 66, Issue 1, 2012, Pages 67-74

  Das, Nirupam ^a   Dash, Biswajit ^a   Dhanawat, Meenakshi ^a   Shrivastava, Sushant Kumar ^a  

^a BANARAS HINDU UNIVERSITY   (India)

Author keywords

anticonvulsant; antidepressant; docking; yrazoline

Indexed keywords

EID: 83555164956     PISSN: 03666352     EISSN: 13369075     Source Type: Journal    
DOI: 10.2478/s11696-011-0106-2     Document Type: Article

References (27)

1. N. D. Amnerkar K. P. Bhusari 2010 Synthesis, anticonvulsant activity and 3D-QSAR study of some prop-2-eneamido and 1-acetyl-pyrazolin derivatives of aminoben zothiazole European Journal of Medicinal Chemistry 45 149 159 1:CAS:528:DC%2BD1MXhsF2ju7zO
2. A. E. E. Amr N. A. Abdel-Latif M. M. Abdalla 2006 Synthesis and antiandrogenic activity of some new 3-substituted androstano[17,16-c]-5′- aryl-pyrazoline and their derivatives Bioorganic & Medicinal Chemistry 14 373 384 1:CAS:528:DC%2BD2MXhtlSiur3F (Pubitemid 41767597)
3. M. Bourin M. Hascoët M. C. Colombel R. T. Coutts G. B. Baker 2002 Clonidine potentiates the effects of tranylcypromine, phenelzine and two analogues in the forced swimming test in mice Journal of Psychiatry & Neuroscience 27 178 185 (Pubitemid 34693928)
4. A. Casimiro-Garcia D. A. Dudley R. J. Heemstra K. J. Filipski C. F. Bigge J. J. Edmunds 2006 Progress in the discovery of factor Xa inhibitors Expert Opinion on Therapeutic Patents 16 119 145 1:CAS:528:DC%2BD28XotlGgtA%3D%3D (Pubitemid 43263237)
5. F. Chimenti A. Bolasco F. Manna D. Secci P. Chimenti O. Befani P. Turini V. Giovannini B. Mondovì R. Cirilli F. La Torre 2004 Synthesis and selective inhibitory activity of 1-acetyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazole derivatives against monoamine oxidase Journal of Medicinal Chemistry 47 2071 2074 1:CAS:528:DC%2BD2cXitVOqurw%3D (Pubitemid 38453922)
6. F. Chimenti S. Carradori D. Secci A. Bolasco B. Bizzarri P. Chimenti A. Granese M. Yáñez F. Orallo 2010 Synthesis and inhibitory activity against human monoamine oxidase of N1-thiocarbamoyl-3,5-di(hetero)aryl-4,5- dihydro-(1H)-pyrazole derivatives European Journal of Medicinal Chemistry 45 800 804 1:CAS:528:DC%2BC3cXos1Smtg%3D%3D
7. F. Chimenti R. Fioravanti A. Bolasco F. Manna P. Chimenti D. Secci F. Rossi P. Turini F. Ortuso S. Alcaro M. C. Cardia 2008 Synthesis, molecular modeling studies and selective inhibitory activity against MAO of N1-propanoyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazole derivatives European Journal of Medicinal Chemistry 43 2262 2267 1:CAS:528:DC%2BD1cXht1CqsLbF
8. L. De Colibus M. Li C. Binda A. Lustig D. E. Edmondson A. Mattevi 2005 Three-dimensional structure of human monoamine oxidase A (MAO A): relation to the structures of rat MAO A and human MAO B Proceedings of the National Academy of Sciences USA 102 12684 12689 (Pubitemid 41279426)
9. A. H. F. A. El-Wahab Z. I. A. Al-Fifi A. H. Bedair F. M. Ali A. H. A. Halawa A. M. El-Agrody 2011 Synthesis, reactions and biological evaluation of some new naphtho[2,1-b]furan derivatives bearing a pyrazole nucleus Molecules 16 307 318
10. R. Fioravanti A. Bolasco F. Manna F. Rossi F. Orallo F. Ortuso S. Alcaro R. Cirilli 2010 Synthesis and biological evaluation of N-substituted-3,5- diphenyl-2-pyrazoline derivatives as cyclooxygenase (COX-2) inhibitors European Journal of Medicinal Chemistry 45 6135 6138 1:CAS:528:DC%2BC3cXhsVGit7rF
11. J. S. Fowler J. Logan A. J. Azzaro R. M. Fielding W. Zhu A. K. Poshusta D. Burch B. Brand J. Free M. Asgharnejad G. J. Wang F. Telang B. Hubbard M. Jayne P. King P. Carter S. Carter Y. Xu C. Shea L. Muench D. Alexoff E. Shumay M. Schueller D. Warner K. Apelskog-Torres 2010 Reversible inhibitors of monoamine oxidase-A (RIMAs): robust, reversible inhibition of human brain MAO-A by CX157 Neuropsychopharmacology 35 623 631 1:CAS:528:DC%2BC3cXht1yht7s%3D
12. S. Gok M. M. Demet A. Özdemir G. Turan-Zitouni 2010 Evaluation of antidepressant-like effect of 2-pyrazoline derivatives Medicinal Chemistry Research 19 94 101 1:CAS:528:DC%2BD1MXjt1Ggu70%3D
13. T. A. Halgren R. B. Murphy R. A. Friesner H. S. Beard L. L. Frye W. T. Pollard J. L. Banks 2004 Glide: a new approach for rapid, accurate docking and scoring. 2. Enrichment factors in database screening Journal of Medicinal Chemistry 47 1750 1759 1:CAS:528:DC%2BD2cXhsFyit78%3D (Pubitemid 38380918)
14. Z. Jia Q. Zhu 2010 'Click' assembly of selective inhibitors for MAO-A Bioorganic & Medicinal Chemistry Letters 20 6222 6225 1:CAS:528: DC%2BC3cXht1KrsbjN
15. Z. A. Kaplancikli A. Özdemir G. Turan-Zitouni M. D. Altintop O. D. Can 2010 New pyrazoline derivatives and their antidepressant activity European Journal of Medicinal Chemistry 45 4383 4387 1:CAS:528:DC%2BC3cXpvFKhtbc%3D
16. M. Karuppasamy M. Mahapatra S. Yabanoglu G. Ucar B. N. Sinha A. Basu N. Mishra A. Sharon U. Kulandaivelu V. Jayaprakash 2010 Development of selective and reversible pyrazoline based MAO-A inhibitors: Synthesis, biological evaluation and docking studies Bioorganic & Medicinal Chemistry 18 1875 1881 1:CAS:528:DC%2BC3cXis1Wqtb8%3D
17. R. L. Krall J. K. Penry B. G. White H. J. Kupferberg E. A. Swinyard 1978 Antiepileptic drug development: II. Anticonvulsant drug screening Epilepsia 19 409 428 1:STN:280:DyaE1M%2FisVGkuw%3D%3D (Pubitemid 9016848)
18. F. Manna F. Chimenti A. Bolasco D. Secci B. Bizzarri O. Befani P. Turini B. Mondovi S. Alcaro A. Tafi 2002 Inhibition of amine oxidases activity by 1-acetyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazole derivatives Bioorganic & Medicinal Chemistry Letters 12 3629 3633 1:CAS:528:DC%2BD38Xoslykt7o%3D (Pubitemid 35346503)
19. Motulsky, H. (1984). GraphPad InStat version 3.01 for Windows 95 (GraphPad software). San Diego, CA, USA: GraphPad Software, Inc.
20. Z. Ozdemir H. B. Kandilci B. Gumusel U. Calis A. A. Bilgin 2008 Synthesis and studies on antidepressant and anticonvulsant activities of some 3-(2-thienyl) pyrazoline derivatives Archiv der Pharmazie 341 701 707 1:CAS:528:DC%2BD1cXhsVOgsrbI
21. B. Petit-Demouliere F. Chenu M. Bourin 2005 Forced swimming test in mice: a review of antidepressant activity Psychopharmacology 177 245 255 1:CAS:528:DC%2BD2cXhtVyltLrE (Pubitemid 40137284)
22. R. D. Porsolt A. Bertin M. Jalfre 1977 Behavioral despair in mice: a primary screening test for antidepressants Archives Internationales de Pharmacodynamie et de Thérapie 229 327 336 1:CAS:528:DyaE1cXktlKgsbs%3D (Pubitemid 8225714)
23. Y. R. Prasad A. L. Rao L. Prasoona K. Murali P. R. Kumar 2005 Synthesis and antidepressant activity of some 1,3,5-triphenyl-2-pyrazolines and 3-(2″-hydroxy naphthalen-1″-yl)-1,5-diphenyl-2-pyrazolines Bioorganic & Medicinal Chemistry Letters 15 5030 5034 1:CAS:528: DC%2BD2MXhtVynu73M (Pubitemid 41400179)
24. Rani, M., Yusuf, M., Khan, S. A., Sahota, P. P., & Pandove, G. (2011). Synthesis, studies and in-vitro antibacterial activity of N-substituted 5-(furan-2-yl)-phenyl pyrazolines. Arabian Journal of Chemistry, in press. DOI: 10.1016/j.jscs.2011.02.012.
25. N. Siddiqui P. Alam W. Ahsan 2009 Design, synthesis, and in-vivo pharmacological screening of N,3-(substituted diphenyl)-5-phenyl-1H-pyrazoline- 1-carbothioamide derivatives Archiv der Pharmazie 342 173 181 1:CAS:528:DC%2BD1MXktVSkt78%3D
26. Vogel, H. G. (2002). Rotarod method. In Drug discovery and evaluation: Pharmacological assays (pp. 398). New York, NY, USA: Springer.
27. M. B. H. Youdim D. Edmondson K. F. Tipton 2006 The therapeutic potential of monoamine oxidase inhibitors Nature Reviews Neuroscience 7 295 309 1:CAS:528:DC%2BD28Xis1Gksrs%3D