-
2
-
-
0037043658
-
Inflammatory bowel disease
-
DOI 10.1056/NEJMra020831
-
Podolsky DK,. Inflammatory bowel disease. N Engl J Med. 2002; 347: 417-429. (Pubitemid 34851835)
-
(2002)
New England Journal of Medicine
, vol.347
, Issue.6
, pp. 417-429
-
-
Podolsky, D.K.1
-
3
-
-
33748293143
-
Etiopathogenesis of inflammatory bowel diseases
-
Danese S, Fiocchi C,. Etiopathogenesis of inflammatory bowel diseases. World J Gastroenterol. 2006; 12: 4807-4812. (Pubitemid 44323204)
-
(2006)
World Journal of Gastroenterology
, vol.12
, Issue.30
, pp. 4807-4812
-
-
Danese, S.1
Fiocchi, C.2
-
4
-
-
0035978533
-
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
-
DOI 10.1038/35079114
-
Ogura Y, Bonen DK, Inohara N, et al. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature. 2001; 411: 603-606. (Pubitemid 32531409)
-
(2001)
Nature
, vol.411
, Issue.6837
, pp. 603-606
-
-
Ogura, Y.1
Bonen, D.K.2
Inohara, N.3
Nicolae, D.L.4
Chen, F.F.5
Ramos, R.6
Britton, H.7
Moran, T.8
Karaliuskas, R.9
Duerr, R.H.10
Achkar, J.-P.11
Brant, S.R.12
Bayless, T.M.13
Kirschner, B.S.14
Hanauer, S.B.15
Nuez, G.16
Cho, J.H.17
-
5
-
-
33847381116
-
The fundamental basis of inflammatory bowel disease
-
DOI 10.1172/JCI30587
-
Strober W, Fuss I, Mannon P,. The fundamental basis of inflammatory bowel disease. J Clin Invest. 2007; 117: 514-521. (Pubitemid 46348505)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.3
, pp. 514-521
-
-
Strober, W.1
Fuss, I.2
Mannon, P.3
-
6
-
-
77951260924
-
The role of pattern-recognition receptors in innate immunity: Update on Toll-like receptors
-
Kawai T, Akira S,. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol. 2010; 11: 373-384.
-
(2010)
Nat Immunol.
, vol.11
, pp. 373-384
-
-
Kawai, T.1
Akira, S.2
-
7
-
-
0033600604
-
The beginning of the end: IkappaB kinase (IKK) and NF-kappaB activation
-
Karin M,. The beginning of the end: IkappaB kinase (IKK) and NF-kappaB activation. J Biol Chem. 1999; 274: 27339-27342.
-
(1999)
J Biol Chem.
, vol.274
, pp. 27339-27342
-
-
Karin, M.1
-
9
-
-
30744462300
-
Regulation of lung injury and repair by Toll-like receptors and hyaluronan
-
DOI 10.1038/nm1315, PII NM1315
-
Jiang D, Liang J, Fan J, et al. Regulation of lung injury and repair by Toll-like receptors and hyaluronan. Nat Med. 2005; 11: 1173-1179. (Pubitemid 43093664)
-
(2005)
Nature Medicine
, vol.11
, Issue.11
, pp. 1173-1179
-
-
Jiang, D.1
Liang, J.2
Fan, J.3
Yu, S.4
Chen, S.5
Luo, Y.6
Prestwich, G.D.7
Mascarenhas, M.M.8
Garg, H.G.9
Quinn, D.A.10
Homer, R.J.11
Goldstein, D.R.12
Bucala, R.13
Lee, P.J.14
Medzhitov, R.15
Noble, P.W.16
-
10
-
-
23644456849
-
The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages
-
DOI 10.1172/JCI23755
-
Schaefer L, Babelova A, Kiss E, et al. The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages. J Clin Invest. 2005; 115: 2223-2233. (Pubitemid 41134165)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.8
, pp. 2223-2233
-
-
Schaefer, L.1
Babelova, A.2
Kiss, E.3
Hausser, H.-J.4
Baliova, M.5
Krzyzankova, M.6
Marsche, G.7
Young, M.F.8
Mihalik, D.9
Gotte, M.10
Malle, E.11
Schaefer, R.M.12
Grone, H.-J.13
-
11
-
-
0346496019
-
The extracellular matrix protein mindin is a pattern-recognition molecule for microbial pathogens
-
DOI 10.1038/ni1021
-
He YW, Li H, Zhang J, et al. The extracellular matrix protein mindin is a pattern-recognition molecule for microbial pathogens. Nat Immunol. 2004; 5: 88-97. (Pubitemid 38081473)
-
(2004)
Nature Immunology
, vol.5
, Issue.1
, pp. 88-97
-
-
He, Y.-W.1
Li, H.2
Zhang, J.3
Hsu, C.-L.4
Lin, E.5
Zhang, N.6
Guo, J.7
Forbush, K.A.8
Bevan, M.J.9
-
12
-
-
0344792632
-
A Murine Model of Chronic Inflammation-Induced Intestinal Fibrosis Down-Regulated by Antisense NF-κB
-
DOI 10.1053/j.gastro.2003.08.027
-
Lawrance IC, Wu F, Leite AZ, et al. A murine model of chronic inflammation-induced intestinal fibrosis down-regulated by antisense NF-kappa B. Gastroenterology. 2003; 125: 1750-1761. (Pubitemid 37500440)
-
(2003)
Gastroenterology
, vol.125
, Issue.6
, pp. 1750-1761
-
-
Lawrance, I.C.1
Wu, F.2
Leite, A.Z.A.3
Willis, J.4
West, G.A.5
Fiocchi, C.6
Chakravarti, S.7
-
13
-
-
38449104349
-
Differential expression of inflammatory and fibrogenic genes and their regulation by NF-{kappa}B inhibition in a mouse model of chronic colitis
-
Wu F, Chakravarti S,. Differential expression of inflammatory and fibrogenic genes and their regulation by NF-{kappa}B inhibition in a mouse model of chronic colitis. J Immunol. 2007; 179: 6988-7000.
-
(2007)
J Immunol.
, vol.179
, pp. 6988-7000
-
-
Wu, F.1
Chakravarti, S.2
-
14
-
-
34548861475
-
A novel role of the lumican core protein in bacterial lipopolysaccharide- induced innate immune response
-
DOI 10.1074/jbc.M702402200
-
Wu F, Vij N, Roberts L, et al. A novel role of the lumican core protein in bacterial lipopolysaccharide-induced innate immune response. J Biol Chem. 2007; 282: 26409-26417. (Pubitemid 47443780)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.36
, pp. 26409-26417
-
-
Wu, F.1
Vij, N.2
Roberts, L.3
Lopez-Briones, S.4
Joyce, S.5
Chakravarti, S.6
-
15
-
-
0032101311
-
Lumican regulates collagen fibril assembly: Skin fragility and corneal opacity in the absence of lumican
-
DOI 10.1083/jcb.141.5.1277
-
Chakravarti S, Magnuson T, Lass JH, et al. Lumican regulates collagen fibril assembly: skin fragility and corneal opacity in the absence of lumican. J Cell Biol. 1998; 141: 1277-1286. (Pubitemid 28265620)
-
(1998)
Journal of Cell Biology
, vol.141
, Issue.5
, pp. 1277-1286
-
-
Chakravarti, S.1
Magnuson, T.2
Lass, J.H.3
Jepsen, K.J.4
LaMantia, C.5
Carroll, H.6
-
17
-
-
0026585781
-
RAG-1-deficient mice have no mature B and T lymphocytes
-
Mombaerts P, Iacomini J, Johnson RS, et al. RAG-1-deficient mice have no mature B and T lymphocytes. Cell. 1992; 68: 869-877.
-
(1992)
Cell.
, vol.68
, pp. 869-877
-
-
Mombaerts, P.1
Iacomini, J.2
Johnson, R.S.3
-
18
-
-
31544469833
-
Role of T-cell-associated lymphocyte function-associated antigen-1 in the pathogenesis of experimental colitis
-
DOI 10.1093/intimm/dxh378
-
Pavlick KP, Ostanin DV, Furr KL, et al. Role of T-cell-associated lymphocyte function-associated antigen-1 in the pathogenesis of experimental colitis. Int Immunol. 2006; 18: 389-398. (Pubitemid 43160151)
-
(2006)
International Immunology
, vol.18
, Issue.2
, pp. 389-398
-
-
Pavlick, K.P.1
Ostanin, D.V.2
Furr, K.L.3
Laroux, F.S.4
Brown, C.M.5
Gray, L.6
Kevil, C.G.7
Grisham, M.B.8
-
19
-
-
0141651913
-
Functions of lumican and fibromodulin: Lessons from knockout mice
-
DOI 10.1023/A:1025348417078
-
Chakravarti S,. Functions of lumican and fibromodulin: lessons from knockout mice. Glycoconj J. 2002; 19: 287-293. (Pubitemid 37174557)
-
(2002)
Glycoconjugate Journal
, vol.19
, Issue.4-5
, pp. 287-293
-
-
Chakravarti, S.1
-
20
-
-
0029160769
-
Primary structure of human lumican (keratan sulfate proteoglycan) and localization of the gene (LUM) to chromosome 12q21.3-q22
-
Chakravarti S, Stallings RL, SundarRaj N, et al. Primary structure of human lumican (keratan sulfate proteoglycan) and localization of the gene (LUM) to chromosome 12q21.3-q22. Genomics. 1995; 27: 481-488.
-
(1995)
Genomics.
, vol.27
, pp. 481-488
-
-
Chakravarti, S.1
Stallings, R.L.2
Sundarraj, N.3
-
21
-
-
69949142985
-
Extracellular matrix lumican deposited on the surface of neutrophils promotes migration by binding to beta2 integrin
-
Lee S, Bowrin K, Hamad AR, et al. Extracellular matrix lumican deposited on the surface of neutrophils promotes migration by binding to beta2 integrin. J Biol Chem. 2009; 284: 23662-23669.
-
(2009)
J Biol Chem.
, vol.284
, pp. 23662-23669
-
-
Lee, S.1
Bowrin, K.2
Hamad, A.R.3
-
22
-
-
0034723293
-
Role of lumican in the corneal epithelium during wound healing
-
DOI 10.1074/jbc.275.4.2607
-
Saika S, Shiraishi A, Liu CY, et al. Role of lumican in the corneal epithelium during wound healing. J Biol Chem. 2000; 275: 2607-2612. (Pubitemid 30082027)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.4
, pp. 2607-2612
-
-
Saika, S.1
Shiraishi, A.2
Saika, S.3
Liu, C.-Y.4
Funderburgh, J.L.5
Kao, C.W.-C.6
Converse, R.L.7
Kao, W.W.-Y.8
-
23
-
-
1642421036
-
Lumican suppresses cell proliferation and aids Fas-Fas ligand mediated apoptosis: Implications in the cornea
-
DOI 10.1016/j.exer.2003.12.006, PII S0014483504000028
-
Vij N, Roberts L, Joyce S, et al. Lumican suppresses cell proliferation and aids Fas-Fas ligand mediated apoptosis: implications in the cornea. Exp Eye Res. 2004; 78: 957-971. (Pubitemid 38402204)
-
(2004)
Experimental Eye Research
, vol.78
, Issue.5
, pp. 957-971
-
-
Vij, N.1
Roberts, L.2
Joyce, S.3
Chakravarti, S.4
-
24
-
-
11144256156
-
Lumican regulates corneal inflammatory responses by modulating Fas-Fas ligand signaling
-
DOI 10.1167/iovs.04-0833
-
Vij N, Roberts L, Joyce S, et al. Lumican regulates corneal inflammatory responses by modulating Fas-Fas ligand signaling. Invest Ophthalmol Vis Sci. 2005; 46: 88-95. (Pubitemid 40041183)
-
(2005)
Investigative Ophthalmology and Visual Science
, vol.46
, Issue.1
, pp. 88-95
-
-
Vij, N.1
Roberts, L.2
Joyce, S.3
Chakravarti, S.4
-
25
-
-
0031593664
-
Role of NF-κB in immune and inflammatory responses in the gut
-
Neurath MF, Becker C, Barbulescu K,. Role of NF-kappaB in immune and inflammatory responses in the gut. Gut. 1998; 43: 856-860. (Pubitemid 28539668)
-
(1998)
Gut
, vol.43
, Issue.6
, pp. 856-860
-
-
Neurath, M.F.1
Becker, C.2
Barbulescu, K.3
-
26
-
-
0029836444
-
Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-κB abrogates established experimental colitis in mice
-
DOI 10.1038/nm0996-998
-
Neurath MF, Pettersson S, Meyer zum Buschenfelde KH, et al. Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-kappa B abrogates established experimental colitis in mice. Nat Med. 1996; 2: 998-1004. (Pubitemid 26306838)
-
(1996)
Nature Medicine
, vol.2
, Issue.9
, pp. 998-1004
-
-
Neurath, M.F.1
Pettersson, S.2
Meyer Zum Buschenfelde, K.-H.3
Strober, W.4
-
27
-
-
0026575942
-
A comparative analysis of two models of colitis in rats
-
Yamada Y, Marshall S, Specian RD, et al. A comparative analysis of two models of colitis in rats. Gastroenterology. 1992; 102: 1524-1534.
-
(1992)
Gastroenterology.
, vol.102
, pp. 1524-1534
-
-
Yamada, Y.1
Marshall, S.2
Specian, R.D.3
-
28
-
-
0028861975
-
Antibodies to interleukin 12 abrogate established experimental colitis in mice
-
Neurath M, Fuss I, Kelsall B, et al. Antibodies to interleukin 12 abrogate established experimental colitis in mice. J Exp Med. 1995; 182: 1281-1290.
-
(1995)
J Exp Med.
, vol.182
, pp. 1281-1290
-
-
Neurath, M.1
Fuss, I.2
Kelsall, B.3
-
29
-
-
38849170507
-
Granulocyte macrophage colony-stimulating factor ameliorates DSS-induced experimental colitis
-
DOI 10.1002/ibd.20279
-
Sainathan SK, Hanna EM, Gong Q, et al. Granulocyte macrophage colony-stimulating factor ameliorates DSS-induced experimental colitis. Inflamm Bowel Dis. 2008; 14: 88-99. (Pubitemid 351196873)
-
(2008)
Inflammatory Bowel Diseases
, vol.14
, Issue.1
, pp. 88-99
-
-
Sainathan, S.K.1
Hanna, E.M.2
Gong, Q.3
Bishnupuri, K.S.4
Luo, Q.5
Colonna, M.6
White, F.V.7
Croze, E.8
Houchen, C.9
Anant, S.10
Dieckgraefe, B.K.11
-
30
-
-
20244372724
-
Toll-like receptor-4 is required for intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis
-
DOI 10.1152/ajpgi.00328.2004
-
Fukata M, Michelsen KS, Eri R, et al. Toll-like receptor-4 is required for intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis. Am J Physiol Gastrointest Liver Physiol. 2005; 288: G1055-1065. (Pubitemid 40563149)
-
(2005)
American Journal of Physiology - Gastrointestinal and Liver Physiology
, vol.288
, Issue.5-51
-
-
Fukata, M.1
Michelsen, K.S.2
Eri, R.3
Thomas, L.S.4
Hu, B.5
Lukasek, K.6
Nast, C.C.7
Lechago, J.8
Xu, R.9
Naiki, Y.10
Soliman, A.11
Arditi, M.12
Abreu, M.T.13
-
31
-
-
38849189905
-
MyD88 signalling plays a critical role in host defence by controlling pathogen burden and promoting epithelial cell homeostasis during Citrobacterrodentium-induced colitis
-
DOI 10.1111/j.1462-5822.2007.01071.x
-
Gibson DL, Ma C, Bergstrom KS, et al. MyD88 signalling plays a critical role in host defence by controlling pathogen burden and promoting epithelial cell homeostasis during Citrobacter rodentium-induced colitis. Cell Microbiol. 2008; 10: 618-631. (Pubitemid 351194091)
-
(2008)
Cellular Microbiology
, vol.10
, Issue.3
, pp. 618-631
-
-
Gibson, D.L.1
Ma, C.2
Bergstrom, K.S.B.3
Huang, J.T.4
Man, C.5
Vallance, B.A.6
-
32
-
-
17044385039
-
TLR signaling in the gut in health and disease
-
Abreu MT, Fukata M, Arditi M,. TLR signaling in the gut in health and disease. J Immunol. 2005; 174: 4453-4460.
-
(2005)
J Immunol.
, vol.174
, pp. 4453-4460
-
-
Abreu, M.T.1
Fukata, M.2
Arditi, M.3
-
33
-
-
33747114270
-
Role of Toll-like Receptors in Spontaneous Commensal-Dependent Colitis
-
DOI 10.1016/j.immuni.2006.06.010, PII S107476130600344X
-
Rakoff-Nahoum S, Hao L, Medzhitov R,. Role of Toll-like receptors in spontaneous commensal-dependent colitis. Immunity. 2006; 25: 319-329. (Pubitemid 44224143)
-
(2006)
Immunity
, vol.25
, Issue.2
, pp. 319-329
-
-
Rakoff-Nahoum, S.1
Hao, L.2
Medzhitov, R.3
-
34
-
-
3242664636
-
Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis
-
DOI 10.1016/j.cell.2004.07.002, PII S0092867404006610
-
Rakoff-Nahoum S, Paglino J, Eslami-Varzaneh F, et al. Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell. 2004; 118: 229-241. (Pubitemid 38962578)
-
(2004)
Cell
, vol.118
, Issue.2
, pp. 229-241
-
-
Rakoff-Nahoum, S.1
Paglino, J.2
Eslami-Varzaneh, F.3
Edberg, S.4
Medzhitov, R.5
-
37
-
-
77954584972
-
Cross-talk between the insulin-like growth factor (IGF) axis and membrane integrins to regulate cell physiology
-
Beattie J, McIntosh L, van der Walle CF,. Cross-talk between the insulin-like growth factor (IGF) axis and membrane integrins to regulate cell physiology. J Cell Physiol. 2010; 224: 605-611.
-
(2010)
J Cell Physiol.
, vol.224
, pp. 605-611
-
-
Beattie, J.1
McIntosh, L.2
Van Der Walle, C.F.3
|