Allosteric modulation by protein kinase Cε leads to modified responses of EGF receptor towards tyrosine kinase inhibitors

Cellular Signalling

Volumn 24, Issue 2, 2012, Pages 422-434

  Weisheit, Simona ^a   Liebmann, Claus ^a  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

Allosteric modulation; EGFR; Gefitinib; HNSCC cells; Lapatinib; PKC

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; GEFITINIB; LAPATINIB; PROTEIN KINASE C EPSILON;

ALLOSTERISM; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CARCINOMA CELL; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DIMERIZATION; DRUG CYTOTOXICITY; DRUG EFFICACY; HEAD AND NECK CARCINOMA; IMMUNOPRECIPITATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SQUAMOUS CELL CARCINOMA; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; CARCINOMA, SQUAMOUS CELL; CELL CYCLE; CELL LINE, TUMOR; DIMERIZATION; FLOW CYTOMETRY; GENE EXPRESSION; HEAD AND NECK NEOPLASMS; HUMANS; IMMUNOPRECIPITATION; PLASMIDS; PROTEIN CONFORMATION; PROTEIN KINASE C-EPSILON; PROTEIN KINASE INHIBITORS; QUINAZOLINES; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, ERBB-2; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 83555161620     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2011.09.010     Document Type: Article

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