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Volumn 28, Issue 1, 2012, Pages 20-27

Microfluidic production of monodisperse biopolymer particles with reproducible morphology by kinetic control

Author keywords

Gelation; Microfluidic; Microparticles; Phase separation

Indexed keywords

BIOMOLECULES; COOLING; LIME; MICROFLUIDICS; MICROSTRUCTURE; PHASE INTERFACES; PHASE SEPARATION; POLYSACCHARIDES;

EID: 83455263804     PISSN: 0268005X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.foodhyd.2011.11.004     Document Type: Article
Times cited : (20)

References (49)
  • 1
    • 0037455351 scopus 로고    scopus 로고
    • Formation of dispersions using flow-focusing in microchannels
    • Anna S.L., Bontoux N., Stone H.A. Formation of dispersions using flow-focusing in microchannels. Applied Physics Letters 2003, 90:364-366.
    • (2003) Applied Physics Letters , vol.90 , pp. 364-366
    • Anna, S.L.1    Bontoux, N.2    Stone, H.A.3
  • 3
    • 0141530988 scopus 로고    scopus 로고
    • Three-dimensional fluorescence recovery after photobleaching with the confocal scanning laser microscope
    • Braeckmans K., Peeters L., Sanders N.N., Smedt D.C.S., Demeester J. Three-dimensional fluorescence recovery after photobleaching with the confocal scanning laser microscope. Biophysical Journal 2003, 85:2240-2252.
    • (2003) Biophysical Journal , vol.85 , pp. 2240-2252
    • Braeckmans, K.1    Peeters, L.2    Sanders, N.N.3    Smedt, D.C.S.4    Demeester, J.5
  • 4
    • 0034607396 scopus 로고    scopus 로고
    • Effect of matrix composition and process conditions on casein-gelatin beads floating properties
    • Bulgarelli E., Forni F., Bernabei M.T. Effect of matrix composition and process conditions on casein-gelatin beads floating properties. International Journal of Pharmaceutics 2000, 198:157-165.
    • (2000) International Journal of Pharmaceutics , vol.198 , pp. 157-165
    • Bulgarelli, E.1    Forni, F.2    Bernabei, M.T.3
  • 6
    • 72049096369 scopus 로고    scopus 로고
    • Preparation and characterization of polysaccharidic microbeads by a microfluidic technique: application to the encapsulation of Sertoli cells
    • Capretto L., Mazzitelli A., Luca G., Nastruzzi C. Preparation and characterization of polysaccharidic microbeads by a microfluidic technique: application to the encapsulation of Sertoli cells. Acta Biomaterialia 2010, 6:429-435.
    • (2010) Acta Biomaterialia , vol.6 , pp. 429-435
    • Capretto, L.1    Mazzitelli, A.2    Luca, G.3    Nastruzzi, C.4
  • 7
    • 33744464045 scopus 로고    scopus 로고
    • Alginate-whey protein granular microspheres as oral delivery vehicles for bioactive compounds
    • Chen L., Subirade M. Alginate-whey protein granular microspheres as oral delivery vehicles for bioactive compounds. Biomaterials 2006, 27:4646-4654.
    • (2006) Biomaterials , vol.27 , pp. 4646-4654
    • Chen, L.1    Subirade, M.2
  • 9
    • 52649128338 scopus 로고    scopus 로고
    • Experimental observation of the squeezing-to-dripping transition in t-shaped microfluidic junctions
    • Christofer G.F., Noharuddin N.N., Taylor J.A., Anna S.L. Experimental observation of the squeezing-to-dripping transition in t-shaped microfluidic junctions. Physical Review Letters 2008, 78:036317.
    • (2008) Physical Review Letters , vol.78 , pp. 036317
    • Christofer, G.F.1    Noharuddin, N.N.2    Taylor, J.A.3    Anna, S.L.4
  • 11
    • 0000084998 scopus 로고
    • Preparation and properties of fluorescent dextrans
    • De Belder A.N., Granath K. Preparation and properties of fluorescent dextrans. Carbohydrate Research 1973, 30:375-378.
    • (1973) Carbohydrate Research , vol.30 , pp. 375-378
    • De Belder, A.N.1    Granath, K.2
  • 12
    • 78149372900 scopus 로고    scopus 로고
    • Straightforward FRAP for quantitative diffusion measurements with a laser scanning microscope
    • Deschout H., Hagman J., Fransson S., Jonasson J., Rudemo M., Lorén N., et al. Straightforward FRAP for quantitative diffusion measurements with a laser scanning microscope. Optics Express 2010, 18(22):22886-22905.
    • (2010) Optics Express , vol.18 , Issue.22 , pp. 22886-22905
    • Deschout, H.1    Hagman, J.2    Fransson, S.3    Jonasson, J.4    Rudemo, M.5    Lorén, N.6
  • 13
    • 0038541889 scopus 로고    scopus 로고
    • Ordered and disordered patterns in two phase flows in microchannels
    • Dreyfus R., Tabeling P., Willaime H. Ordered and disordered patterns in two phase flows in microchannels. Physical Review Letters 2003, 90:144505.
    • (2003) Physical Review Letters , vol.90 , pp. 144505
    • Dreyfus, R.1    Tabeling, P.2    Willaime, H.3
  • 14
    • 44949111502 scopus 로고    scopus 로고
    • Controlled production of emulsions and particles by milli- and microfludic techniques
    • Engl W., Backov R., Panizza P. Controlled production of emulsions and particles by milli- and microfludic techniques. Current Opinion in Colloid & Interface Science 2008, 13:206-216.
    • (2008) Current Opinion in Colloid & Interface Science , vol.13 , pp. 206-216
    • Engl, W.1    Backov, R.2    Panizza, P.3
  • 15
    • 67049087876 scopus 로고    scopus 로고
    • Effect of confinement and kinetics in the morphology of phase separating gelatin-maltodextrin droplets
    • Fransson S., Lorén N., Altskär A., Hermansson A.-M. Effect of confinement and kinetics in the morphology of phase separating gelatin-maltodextrin droplets. Biomacromolecules 2009, 10:1446-1453.
    • (2009) Biomacromolecules , vol.10 , pp. 1446-1453
    • Fransson, S.1    Lorén, N.2    Altskär, A.3    Hermansson, A.-M.4
  • 16
    • 77953312828 scopus 로고    scopus 로고
    • Modelling and confocal microscopy of biopolymer mixtures in confined geometries
    • Fransson S., Peleg O., Lorén N., Hermansson A.-M., Kröger M. Modelling and confocal microscopy of biopolymer mixtures in confined geometries. Soft Matter 2010, 6:2713-2722.
    • (2010) Soft Matter , vol.6 , pp. 2713-2722
    • Fransson, S.1    Peleg, O.2    Lorén, N.3    Hermansson, A.-M.4    Kröger, M.5
  • 17
    • 0000731845 scopus 로고    scopus 로고
    • The use of confocal laser scanning microscopy in studying mixed biopolymer systems
    • IRL Press, University Press, Oxford, P. Williams, G. Phillips (Eds.)
    • Garnier C., Bourriot S., Doublier J.-L. The use of confocal laser scanning microscopy in studying mixed biopolymer systems. Gums and stabilisers for the food industry 1998, Vol. 9:247-256. IRL Press, University Press, Oxford. P. Williams, G. Phillips (Eds.).
    • (1998) Gums and stabilisers for the food industry , vol.9 , pp. 247-256
    • Garnier, C.1    Bourriot, S.2    Doublier, J.-L.3
  • 18
    • 33644648479 scopus 로고    scopus 로고
    • Formation of droplets and bubbles in a microfluidic T-junction. Scaling and mechanism of break-up
    • Garstecki P., Fuerstman M.J., Stone H.A., Whitesides G.M. Formation of droplets and bubbles in a microfluidic T-junction. Scaling and mechanism of break-up. Lab on a Chip 2006, 6:437-446.
    • (2006) Lab on a Chip , vol.6 , pp. 437-446
    • Garstecki, P.1    Fuerstman, M.J.2    Stone, H.A.3    Whitesides, G.M.4
  • 19
    • 34548590903 scopus 로고    scopus 로고
    • Stability of a jet in confined pressure-driven biphasic flows at low Reynolds numbers
    • Guillot P., Colin A., Utada A.S., Adjari A. Stability of a jet in confined pressure-driven biphasic flows at low Reynolds numbers. Physical Review Letters 2007, 99:104502.
    • (2007) Physical Review Letters , vol.99 , pp. 104502
    • Guillot, P.1    Colin, A.2    Utada, A.S.3    Adjari, A.4
  • 21
    • 67349199958 scopus 로고    scopus 로고
    • Microfluidic controlling monodisperse microdroplets for 5-fluorouracil loaded genipin-gelatin microcapsules
    • Huang K.-S., Lu K., Yeh C.-S., Chung S.-R., Lin C.-H., Yang C.-H., et al. Microfluidic controlling monodisperse microdroplets for 5-fluorouracil loaded genipin-gelatin microcapsules. Journal of Controlled Release 2009, 137:15-19.
    • (2009) Journal of Controlled Release , vol.137 , pp. 15-19
    • Huang, K.-S.1    Lu, K.2    Yeh, C.-S.3    Chung, S.-R.4    Lin, C.-H.5    Yang, C.-H.6
  • 23
    • 77955303909 scopus 로고    scopus 로고
    • Facile control of porous structure of polymer microspheres using an osmotic agent for pulmonary delivery
    • Lee J., Oh Y.J., Lee S.K., Lee K.Y. Facile control of porous structure of polymer microspheres using an osmotic agent for pulmonary delivery. Journal of Controlled Release 2010, 146:61-67.
    • (2010) Journal of Controlled Release , vol.146 , pp. 61-67
    • Lee, J.1    Oh, Y.J.2    Lee, S.K.3    Lee, K.Y.4
  • 24
    • 64249124693 scopus 로고    scopus 로고
    • Role of geometry and fluid properties in droplet and thread formation processes in planar flow focusing
    • Lee W., Walker L.M., Anna S.L. Role of geometry and fluid properties in droplet and thread formation processes in planar flow focusing. Physics of Fluids 2009, 21:032103.
    • (2009) Physics of Fluids , vol.21 , pp. 032103
    • Lee, W.1    Walker, L.M.2    Anna, S.L.3
  • 25
    • 0035818656 scopus 로고    scopus 로고
    • Structure evolution during gelation at later stages of spinodal decomposition in gelatin/maltodextrin mixtures
    • Lorén N., Altskär A., Hermansson A.-M. Structure evolution during gelation at later stages of spinodal decomposition in gelatin/maltodextrin mixtures. Macromolecules 2001, 34:8117-8128.
    • (2001) Macromolecules , vol.34 , pp. 8117-8128
    • Lorén, N.1    Altskär, A.2    Hermansson, A.-M.3
  • 28
    • 0000312469 scopus 로고    scopus 로고
    • Confocal laser scanning microscopy and image analysis of kinetically trapped phase-separation gelatin/maltodextrin gels
    • Lorén N., Langton M., Hermansson A.-M. Confocal laser scanning microscopy and image analysis of kinetically trapped phase-separation gelatin/maltodextrin gels. Food Hydrocolloids 1999, 13:185-198.
    • (1999) Food Hydrocolloids , vol.13 , pp. 185-198
    • Lorén, N.1    Langton, M.2    Hermansson, A.-M.3
  • 31
    • 77955057374 scopus 로고    scopus 로고
    • Fabrication and characterization of filled hydrogel particles based on sequential segregative and aggregative biopolymer phase separation
    • Matalanis A., Lesmes U., Decker E.A., McClements D.J. Fabrication and characterization of filled hydrogel particles based on sequential segregative and aggregative biopolymer phase separation. Food Hydrocolloids 2010, 24:689-701.
    • (2010) Food Hydrocolloids , vol.24 , pp. 689-701
    • Matalanis, A.1    Lesmes, U.2    Decker, E.A.3    McClements, D.J.4
  • 32
    • 49149101874 scopus 로고    scopus 로고
    • In vitro release of bovine serum albumin from alginate/HPMC hydrogel beads
    • Nochos A., Douroumis D., Bouropoulos N. In vitro release of bovine serum albumin from alginate/HPMC hydrogel beads. Carbohydrate Polymers 2008, 74:451-457.
    • (2008) Carbohydrate Polymers , vol.74 , pp. 451-457
    • Nochos, A.1    Douroumis, D.2    Bouropoulos, N.3
  • 33
    • 0035189392 scopus 로고    scopus 로고
    • Microstructure design in mixed biopolymer composites
    • Norton I.T., Frith W.J. Microstructure design in mixed biopolymer composites. Food Hydrocolloids 2001, 15:543-553.
    • (2001) Food Hydrocolloids , vol.15 , pp. 543-553
    • Norton, I.T.1    Frith, W.J.2
  • 34
    • 47349107407 scopus 로고    scopus 로고
    • Biopolymer microparticle and nanoparticle formation within a microfluidic device
    • Rondeau E., Cooper-White J.J. Biopolymer microparticle and nanoparticle formation within a microfluidic device. Langmuir 2008, 24:6937-6945.
    • (2008) Langmuir , vol.24 , pp. 6937-6945
    • Rondeau, E.1    Cooper-White, J.J.2
  • 35
    • 0027327772 scopus 로고
    • Influence of manufacturing parameters on the size characteristics and the release profiles of nifedipine from poly(DL-lactide-co-glycolide) microspheres
    • Sansdrap S., Moës A.J. Influence of manufacturing parameters on the size characteristics and the release profiles of nifedipine from poly(DL-lactide-co-glycolide) microspheres. International Journal of Pharmaceutics 1993, 98:157-164.
    • (1993) International Journal of Pharmaceutics , vol.98 , pp. 157-164
    • Sansdrap, S.1    Moës, A.J.2
  • 36
    • 36148988769 scopus 로고    scopus 로고
    • M-PIV study of the formation of segmented flow in microfluidic T-junctions
    • van Steijn V., Kreuzer M.T., Kleijn C.R. m-PIV study of the formation of segmented flow in microfluidic T-junctions. Chemical Engineering Science 2007, 62:7505-7514.
    • (2007) Chemical Engineering Science , vol.62 , pp. 7505-7514
    • van Steijn, V.1    Kreuzer, M.T.2    Kleijn, C.R.3
  • 37
    • 70349331511 scopus 로고    scopus 로고
    • A brief introduction to slippage, droplets and mixing in microfluidic systems
    • Tabeling P. A brief introduction to slippage, droplets and mixing in microfluidic systems. Lab on a Chip 2009, 9:2428-2436.
    • (2009) Lab on a Chip , vol.9 , pp. 2428-2436
    • Tabeling, P.1
  • 38
    • 59049085704 scopus 로고    scopus 로고
    • Review: doxorubicin delivery systems based on chitosan for cancer therapy
    • Tan M.L., Choong P.F.M., Dass C.R. Review: doxorubicin delivery systems based on chitosan for cancer therapy. Journal of Pharmacy and Pharmacology 2009, 61:131-142.
    • (2009) Journal of Pharmacy and Pharmacology , vol.61 , pp. 131-142
    • Tan, M.L.1    Choong, P.F.M.2    Dass, C.R.3
  • 40
  • 41
    • 0037243795 scopus 로고    scopus 로고
    • Some thermodynammic considerations in food formulation
    • Tolstoguzov V. Some thermodynammic considerations in food formulation. Food Hydrocolloids 2003, 17:1-23.
    • (2003) Food Hydrocolloids , vol.17 , pp. 1-23
    • Tolstoguzov, V.1
  • 42
    • 79952315769 scopus 로고    scopus 로고
    • Why and how to prepare biodegradable, monodispersed, polymeric microparticles in the field of pharmacy?
    • Tran V.-T., Benoît J.-P., Venier-Julienne M.-C. Why and how to prepare biodegradable, monodispersed, polymeric microparticles in the field of pharmacy?. International Journal of Pharmaceutics 2011, 407:1-11.
    • (2011) International Journal of Pharmaceutics , vol.407 , pp. 1-11
    • Tran, V.-T.1    Benoît, J.-P.2    Venier-Julienne, M.-C.3
  • 43
    • 0033640011 scopus 로고    scopus 로고
    • Monodisperse emulsion generation via drop break off in a coflowing stream
    • Umbanhowar P.B., Prasad V., Weitz D.A. Monodisperse emulsion generation via drop break off in a coflowing stream. Langmuir 2000, 16:347-351.
    • (2000) Langmuir , vol.16 , pp. 347-351
    • Umbanhowar, P.B.1    Prasad, V.2    Weitz, D.A.3
  • 45
    • 67749133574 scopus 로고    scopus 로고
    • Preparation of monodisperse biodegradable polymer microparticles using a microfluidic flow-focusing device for controlled drug delivery
    • Xu Q., Hashimoto M., Dang T.T., Hoare T., Kohane D.S., Whitesides G.M., et al. Preparation of monodisperse biodegradable polymer microparticles using a microfluidic flow-focusing device for controlled drug delivery. Small 2009, 5(13):1575-1581.
    • (2009) Small , vol.5 , Issue.13 , pp. 1575-1581
    • Xu, Q.1    Hashimoto, M.2    Dang, T.T.3    Hoare, T.4    Kohane, D.S.5    Whitesides, G.M.6
  • 46
    • 0028105002 scopus 로고
    • Characterization and morphological analysis of protein-loaded poly(lactide-co-glycolide) microparticles prepared by water-in-oil-in-water emulsion technique
    • Yan C., Resau J.H., Hewetson J., West M., Rill W.L., Kende M. Characterization and morphological analysis of protein-loaded poly(lactide-co-glycolide) microparticles prepared by water-in-oil-in-water emulsion technique. Journal of Controlled Release 1994, 32(3):231-241.
    • (1994) Journal of Controlled Release , vol.32 , Issue.3 , pp. 231-241
    • Yan, C.1    Resau, J.H.2    Hewetson, J.3    West, M.4    Rill, W.L.5    Kende, M.6
  • 47
    • 34147124963 scopus 로고    scopus 로고
    • Manufacturing monodisperse chitosan microparticles containing ampicillin using a microchannel chip
    • Yang C.-H., Huang K.-S., Chang J.-Y. Manufacturing monodisperse chitosan microparticles containing ampicillin using a microchannel chip. Biomedical Microdevices 2007, 9:253-259.
    • (2007) Biomedical Microdevices , vol.9 , pp. 253-259
    • Yang, C.-H.1    Huang, K.-S.2    Chang, J.-Y.3
  • 48
    • 64549095212 scopus 로고    scopus 로고
    • Using a t-junction microfluidic chip for monodisperse calcium alginate microparticles and encapsulation of nanoparticles
    • Yeh C.-H., Zhao Q., Lee S.-J., Lin Y.-C. Using a t-junction microfluidic chip for monodisperse calcium alginate microparticles and encapsulation of nanoparticles. Sensors and Actuators A: Physical 2009, 151:231-236.
    • (2009) Sensors and Actuators A: Physical , vol.151 , pp. 231-236
    • Yeh, C.-H.1    Zhao, Q.2    Lee, S.-J.3    Lin, Y.-C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.