-
1
-
-
54249104026
-
The ubiquitin system, disease, and drug discovery
-
Petroski, M. D. The ubiquitin system, disease, and drug discovery. BMC Biochem., 2008, 9 (Suppl 1), S7.
-
(2008)
BMC Biochem
, vol.9
, Issue.SUPPL. 1
-
-
Petroski, M.D.1
-
2
-
-
65249098267
-
Catalytic mechanism and assembly of the proteasome
-
Marques, A. J.; Palanimurugan, R.; Matias, A. C.; Ramos, P. C.; Dohmen, R. J. Catalytic mechanism and assembly of the proteasome. Chem. Rev., 2009, 109, 1509-1536.
-
(2009)
Chem. Rev
, vol.109
, pp. 1509-1536
-
-
Marques, A.J.1
Palanimurugan, R.2
Matias, A.C.3
Ramos, P.C.4
Dohmen, R.J.5
-
3
-
-
48949085430
-
Role of proteasomes in cellular regulation
-
Konstantinova, I. M.; Tsimokha, A. S.; Mittenberg, A. G. Role of proteasomes in cellular regulation. Int. Rev. Cell. Mol. Biol., 2008, 267, 59-124.
-
(2008)
Int. Rev. Cell. Mol. Biol
, vol.267
, pp. 59-124
-
-
Konstantinova, I.M.1
Tsimokha, A.S.2
Mittenberg, A.G.3
-
4
-
-
58149159907
-
Dysfunction of the ubiquitin-proteasome system in multiple disease conditions: Therapeutic approaches
-
Paul, S. Dysfunction of the ubiquitin-proteasome system in multiple disease conditions: therapeutic approaches. Bioessays, 2008, 30, 1172-1184.
-
(2008)
Bioessays
, vol.30
, pp. 1172-1184
-
-
Paul, S.1
-
5
-
-
77954125336
-
Peripheral neuropathy during bortezomib treatment of multiple myeloma: A review of recent studies
-
Cavaletti, G.; Jakubowiak, A. J. Peripheral neuropathy during bortezomib treatment of multiple myeloma: a review of recent studies. Leuk. Lymphoma, 2010, 51, 1178-1187.
-
(2010)
Leuk. Lymphoma
, vol.51
, pp. 1178-1187
-
-
Cavaletti, G.1
Jakubowiak, A.J.2
-
6
-
-
77955712506
-
Bortezomib-resistant myeloma cell lines: A role for mutated PSMB5 in preventing the accumulation of unfolded proteins and fatal ER stress
-
Ri, M.; Iida, S.; Nakashima, T.; Miyazaki, H.; Mori, F.; Ito, A.; Inagaki, A.; Kusumoto, S.; Ishida, T.; Komatsu, H.; Shiotsu, Y.; Ueda, R. Bortezomib-resistant myeloma cell lines: a role for mutated PSMB5 in preventing the accumulation of unfolded proteins and fatal ER stress. Leukemia, 2010, 24, 1506-1512.
-
(2010)
Leukemia
, vol.24
, pp. 1506-1512
-
-
Ri, M.1
Iida, S.2
Nakashima, T.3
Miyazaki, H.4
Mori, F.5
Ito, A.6
Inagaki, A.7
Kusumoto, S.8
Ishida, T.9
Komatsu, H.10
Shiotsu, Y.11
Ueda, R.12
-
7
-
-
70450285396
-
Acquisition of a multidrug-resistant phenotype with a proteasome inhibitor in multiple myeloma
-
Gutman, D.; Morales, A. A.; Boise, L. H. Acquisition of a multidrug-resistant phenotype with a proteasome inhibitor in multiple myeloma. Leukemia, 2009, 23, 2181-2183.
-
(2009)
Leukemia
, vol.23
, pp. 2181-2183
-
-
Gutman, D.1
Morales, A.A.2
Boise, L.H.3
-
8
-
-
70450190022
-
Proteasome inhibitors in cancer therapy
-
Testa, U. Proteasome inhibitors in cancer therapy. Curr. Drug Targets, 2009, 10, 968-981.
-
(2009)
Curr. Drug Targets
, vol.10
, pp. 968-981
-
-
Testa, U.1
-
9
-
-
70249146895
-
Single-agent bortezomib in previously untreated multiple myeloma: Efficacy, characterization of peripheral neuropathy, and molecular correlations with response and neuropathy
-
Richardson, P. G.; Xie, W.; Mitsiades, C.; Chanan-Khan, A. A.; Lonial, S.; Hassoun, H.; Avigan, D. E.; Oaklander, A. L.; Kuter, D. J.; Wen, P. Y.; Kesari, S.; Briemberg, H. R.; Schlossman, R. L.; Munshi, N. C.; Heffner, L. T.; Doss, D.; Esseltine, D. L.; Weller, E.; Anderson, K. C.; Amato, A. A. Single-agent bortezomib in previously untreated multiple myeloma: efficacy, characterization of peripheral neuropathy, and molecular correlations with response and neuropathy. J. Clin. Oncol., 2009, 27, 3518-3525.
-
(2009)
J. Clin. Oncol
, vol.27
, pp. 3518-3525
-
-
Richardson, P.G.1
Xie, W.2
Mitsiades, C.3
Chanan-Khan, A.A.4
Lonial, S.5
Hassoun, H.6
Avigan, D.E.7
Oaklander, A.L.8
Kuter, D.J.9
Wen, P.Y.10
Kesari, S.11
Briemberg, H.R.12
Schlossman, R.L.13
Munshi, N.C.14
Heffner, L.T.15
Doss, D.16
Esseltine, D.L.17
Weller, E.18
Anderson, K.C.19
Amato, A.A.20
more..
-
10
-
-
2942692143
-
Phase I trial of the proteasome inhibitor bortezomib in patients with advanced solid tumors with observations in androgen-independent prostate cancer
-
Papandreou, C. N.; Daliani, D. D.; Nix, D.; Yang, H.; Madden, T.; Wang, X.; Pien, C. S.; Millikan, R. E.; Tu, S. M.; Pagliaro, L.; Kim, J.; Adams, J.; Elliott, P.; Esseltine, D.; Petrusich, A.; Dieringer, P.; Perez, C.; Logothetis, C. J. Phase I trial of the proteasome inhibitor bortezomib in patients with advanced solid tumors with observations in androgen-independent prostate cancer. J. Clin. Oncol., 2004, 22, 2108-2121.
-
(2004)
J. Clin. Oncol
, vol.22
, pp. 2108-2121
-
-
Papandreou, C.N.1
Daliani, D.D.2
Nix, D.3
Yang, H.4
Madden, T.5
Wang, X.6
Pien, C.S.7
Millikan, R.E.8
Tu, S.M.9
Pagliaro, L.10
Kim, J.11
Adams, J.12
Elliott, P.13
Esseltine, D.14
Petrusich, A.15
Dieringer, P.16
Perez, C.17
Logothetis, C.J.18
-
11
-
-
66549099025
-
Targeted inhibition of the immunoproteasome is a potent strategy against models of multiple myeloma that overcomes resistance to conventional drugs and nonspecific proteasome inhibitors
-
Kuhn, D. J.; Hunsucker, S. A.; Chen, Q.; Voorhees, P. M.; Orlowski, M.; Orlowski, R. Z. Targeted inhibition of the immunoproteasome is a potent strategy against models of multiple myeloma that overcomes resistance to conventional drugs and nonspecific proteasome inhibitors. Blood, 2009, 113, 4667-4676.
-
(2009)
Blood
, vol.113
, pp. 4667-4676
-
-
Kuhn, D.J.1
Hunsucker, S.A.2
Chen, Q.3
Voorhees, P.M.4
Orlowski, M.5
Orlowski, R.Z.6
-
12
-
-
34247190754
-
LMP2-specific inhibitors: Chemical genetic tools for proteasome biology
-
Ho, Y. K.; Bargagna-Mohan, P.; Wehenkel, M.; Mohan, R.; Kim, K. B. LMP2-specific inhibitors: chemical genetic tools for proteasome biology. Chem. Biol., 2007, 14, 419-430.
-
(2007)
Chem. Biol
, vol.14
, pp. 419-430
-
-
Ho, Y.K.1
Bargagna-Mohan, P.2
Wehenkel, M.3
Mohan, R.4
Kim, K.B.5
-
13
-
-
85038466802
-
-
U. S. Patent 7,691,852, April 6
-
Shenk, K. D.; Parlati, F.; Zhou, H. J.; Sylvain, C.; Smyth, M. S.; Bennett, M. K.; Laidig, G. J.: Compounds for enzyme inhibition. U. S. Patent 7,691,852, April 6, 2010.
-
(2010)
Compounds For Enzyme Inhibition
-
-
Shenk, K.D.1
Parlati, F.2
Zhou, H.J.3
Sylvain, C.4
Smyth, M.S.5
Bennett, M.K.6
Laidig, G.J.7
-
14
-
-
67650388103
-
A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis
-
Muchamuel, T.; Basler, M.; Aujay, M. A.; Suzuki, E.; Kalim, K. W.; Lauer, C.; Sylvain, C.; Ring, E. R.; Shields, J.; Jiang, J.; Shwonek, P.; Parlati, F.; Demo, S. D.; Bennett, M. K.; Kirk, C. J.; Groettrup, M. A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis. Nat. Med., 2009, 15, 781-787.
-
(2009)
Nat. Med
, vol.15
, pp. 781-787
-
-
Muchamuel, T.1
Basler, M.2
Aujay, M.A.3
Suzuki, E.4
Kalim, K.W.5
Lauer, C.6
Sylvain, C.7
Ring, E.R.8
Shields, J.9
Jiang, J.10
Shwonek, P.11
Parlati, F.12
Demo, S.D.13
Bennett, M.K.14
Kirk, C.J.15
Groettrup, M.16
-
16
-
-
0033279836
-
SCF and Cullin/Ring H2-based ubiquitin ligases. Annu
-
Deshaies, R. J. SCF and Cullin/Ring H2-based ubiquitin ligases. Annu. Rev. Cell. Dev. Biol., 1999, 15, 435-467.
-
(1999)
Rev. Cell. Dev. Biol
, vol.15
, pp. 435-467
-
-
Deshaies, R.J.1
-
17
-
-
0033525589
-
A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly
-
Koegl, M.; Hoppe, T.; Schlenker, S.; Ulrich, H. D.; Mayer, T. U.; Jentsch, S. A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly. Cell, 1999, 96, 635-644.
-
(1999)
Cell
, vol.96
, pp. 635-644
-
-
Koegl, M.1
Hoppe, T.2
Schlenker, S.3
Ulrich, H.D.4
Mayer, T.U.5
Jentsch, S.6
-
18
-
-
0030897031
-
Structure of 20S proteasome from yeast at 2.4 A resolution
-
Groll, M.; Ditzel, L.; Lowe, J.; Stock, D.; Bochtler, M.; Bartunik, H. D.; Huber, R. Structure of 20S proteasome from yeast at 2.4 A resolution. Nature, 1997, 386, 463-471.
-
(1997)
Nature
, vol.386
, pp. 463-471
-
-
Groll, M.1
Ditzel, L.2
Lowe, J.3
Stock, D.4
Bochtler, M.5
Bartunik, H.D.6
Huber, R.7
-
19
-
-
0035290730
-
Antigen processing by the proteasome
-
Kloetzel, P. M. Antigen processing by the proteasome. Nat. Rev. Mol. Cell. Biol., 2001, 2, 179-187.
-
(2001)
Nat. Rev. Mol. Cell. Biol
, vol.2
, pp. 179-187
-
-
Kloetzel, P.M.1
-
20
-
-
0025998206
-
Subunit of the '20S' proteasome (multicatalytic proteinase) encoded by the major histocompatibility complex
-
Ortiz-Navarrete, V.; Seelig, A.; Gernold, M.; Frentzel, S.; Kloetzel, P. M.; Hammerling, G. J. Subunit of the '20S' proteasome (multicatalytic proteinase) encoded by the major histocompatibility complex. Nature, 1991, 353, 662-664.
-
(1991)
Nature
, vol.353
, pp. 662-664
-
-
Ortiz-Navarrete, V.1
Seelig, A.2
Gernold, M.3
Frentzel, S.4
Kloetzel, P.M.5
Hammerling, G.J.6
-
21
-
-
0028179233
-
Interferon-gamma induces different subunit organizations and functional diversity of proteasomes
-
Aki, M.; Shimbara, N.; Takashina, M.; Akiyama, K.; Kagawa, S.; Tamura, T.; Tanahashi, N.; Yoshimura, T.; Tanaka, K.; Ichihara, A. Interferon-gamma induces different subunit organizations and functional diversity of proteasomes. J. Biochem. (Tokyo), 1994, 115, 257-269.
-
(1994)
J. Biochem. (Tokyo)
, vol.115
, pp. 257-269
-
-
Aki, M.1
Shimbara, N.2
Takashina, M.3
Akiyama, K.4
Kagawa, S.5
Tamura, T.6
Tanahashi, N.7
Yoshimura, T.8
Tanaka, K.9
Ichihara, A.10
-
22
-
-
0035067590
-
Interferongamma inducible exchanges of 20S proteasome active site subunits: Why?
-
Groettrup, M.; Khan, S.; Schwarz, K.; Schmidtke, G. Interferongamma inducible exchanges of 20S proteasome active site subunits: why? Biochimie, 2001, 83, 367-372.
-
(2001)
Biochimie
, vol.83
, pp. 367-372
-
-
Groettrup, M.1
Khan, S.2
Schwarz, K.3
Schmidtke, G.4
-
23
-
-
0037310166
-
Interferon-gamma-inducible subunits are incorporated in human brain 20S proteasome
-
Piccinini, M.; Mostert, M.; Croce, S.; Baldovino, S.; Papotti, M.; Rinaudo, M. T. Interferon-gamma-inducible subunits are incorporated in human brain 20S proteasome. J. Neuroimmunol., 2003, 135, 135-140.
-
(2003)
J. Neuroimmunol
, vol.135
, pp. 135-140
-
-
Piccinini, M.1
Mostert, M.2
Croce, S.3
Baldovino, S.4
Papotti, M.5
Rinaudo, M.T.6
-
24
-
-
0034652763
-
Biochemical analysis of proteasomes from mouse microglia: Induction of immunoproteasomes by interferon-gamma and lipopolysaccharide
-
Stohwasser, R.; Giesebrecht, J.; Kraft, R.; Muller, E. C.; Hausler, K. G.; Kettenmann, H.; Hanisch, U. K.; Kloetzel, P. M. Biochemical analysis of proteasomes from mouse microglia: induction of immunoproteasomes by interferon-gamma and lipopolysaccharide. Glia, 2000, 29, 355-365.
-
(2000)
Glia
, vol.29
, pp. 355-365
-
-
Stohwasser, R.1
Giesebrecht, J.2
Kraft, R.3
Muller, E.C.4
Hausler, K.G.5
Kettenmann, H.6
Hanisch, U.K.7
Kloetzel, P.M.8
-
25
-
-
0035070697
-
Regulation of proteasome complexes by gamma-interferon and phosphorylation
-
Rivett, A. J.; Bose, S.; Brooks, P.; Broadfoot, K. I. Regulation of proteasome complexes by gamma-interferon and phosphorylation. Biochimie, 2001, 83, 363-366.
-
(2001)
Biochimie
, vol.83
, pp. 363-366
-
-
Rivett, A.J.1
Bose, S.2
Brooks, P.3
Broadfoot, K.I.4
-
26
-
-
21544475903
-
IFN-gammainduced immune adaptation of the proteasome system is an accelerated and transient response
-
Heink, S.; Ludwig, D.; Kloetzel, P. M.; Kruger, E. IFN-gammainduced immune adaptation of the proteasome system is an accelerated and transient response. Proc. Natl. Acad. Sci. USA, 2005, 102, 9241-9246.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 9241-9246
-
-
Heink, S.1
Ludwig, D.2
Kloetzel, P.M.3
Kruger, E.4
-
27
-
-
0035892754
-
Immunoproteasomes largely replace constitutive proteasomes during an antiviral and antibacterial immune response in the liver
-
Khan, S.; van den Broek, M.; Schwarz, K.; de Giuli, R.; Diener, P. A.; Groettrup, M. Immunoproteasomes largely replace constitutive proteasomes during an antiviral and antibacterial immune response in the liver. J. Immunol., 2001, 167, 6859-6868.
-
(2001)
J. Immunol
, vol.167
, pp. 6859-6868
-
-
Khan, S.1
van den Broek, M.2
Schwarz, K.3
de Giuli, R.4
Diener, P.A.5
Groettrup, M.6
-
28
-
-
0031819536
-
The MHC class I ligand-generating system: Roles of immunoproteasomes and the interferon-gammainducible proteasome activator PA28
-
Tanaka, K.; Kasahara, M. The MHC class I ligand-generating system: roles of immunoproteasomes and the interferon-gammainducible proteasome activator PA28. Immunol. Rev., 1998, 163, 161-176.
-
(1998)
Immunol. Rev
, vol.163
, pp. 161-176
-
-
Tanaka, K.1
Kasahara, M.2
-
29
-
-
17944369433
-
Immunoproteasome assembly and antigen presentation in mice lacking both PA28alpha and PA28beta
-
Murata, S.; Udono, H.; Tanahashi, N.; Hamada, N.; Watanabe, K.; Adachi, K.; Yamano, T.; Yui, K.; Kobayashi, N.; Kasahara, M.; Tanaka, K.; Chiba, T. Immunoproteasome assembly and antigen presentation in mice lacking both PA28alpha and PA28beta. Embo J., 2001, 20, 5898-5907.
-
(2001)
Embo J
, vol.20
, pp. 5898-5907
-
-
Murata, S.1
Udono, H.2
Tanahashi, N.3
Hamada, N.4
Watanabe, K.5
Adachi, K.6
Yamano, T.7
Yui, K.8
Kobayashi, N.9
Kasahara, M.10
Tanaka, K.11
Chiba, T.12
-
30
-
-
67649425771
-
The proteasomal system
-
Jung, T.; Catalgol, B.; Grune, T. The proteasomal system. Mol. Aspects Med., 2009, 30, 191-296.
-
(2009)
Mol. Aspects Med
, vol.30
, pp. 191-296
-
-
Jung, T.1
Catalgol, B.2
Grune, T.3
-
31
-
-
27644554700
-
A heterodimeric complex that promotes the assembly of mammalian 20S proteasomes
-
Hirano, Y.; Hendil, K. B.; Yashiroda, H.; Iemura, S.; Nagane, R.; Hioki, Y.; Natsume, T.; Tanaka, K.; Murata, S. A heterodimeric complex that promotes the assembly of mammalian 20S proteasomes. Nature, 2005, 437, 1381-1385.
-
(2005)
Nature
, vol.437
, pp. 1381-1385
-
-
Hirano, Y.1
Hendil, K.B.2
Yashiroda, H.3
Iemura, S.4
Nagane, R.5
Hioki, Y.6
Natsume, T.7
Tanaka, K.8
Murata, S.9
-
32
-
-
0030793290
-
The subunits MECL-1 and LMP2 are mutually required for incorporation into the 20S proteasome
-
Groettrup, M.; Standera, S.; Stohwasser, R.; Kloetzel, P. M. The subunits MECL-1 and LMP2 are mutually required for incorporation into the 20S proteasome. Proc. Natl. Acad. Sci. USA, 1997, 94, 8970-8975.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 8970-8975
-
-
Groettrup, M.1
Standera, S.2
Stohwasser, R.3
Kloetzel, P.M.4
-
33
-
-
0034604609
-
Novel propeptide function in 20 S proteasome assembly influences beta subunit composition
-
Kingsbury, D. J.; Griffin, T. A.; Colbert, R. A. Novel propeptide function in 20 S proteasome assembly influences beta subunit composition. J. Biol. Chem., 2000, 275, 24156-24162.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 24156-24162
-
-
Kingsbury, D.J.1
Griffin, T.A.2
Colbert, R.A.3
-
34
-
-
0031973736
-
Immunoproteasome assembly: Cooperative incorporation of interferon gamma (IFN-gamma)-inducible subunits
-
Griffin, T. A.; Nandi, D.; Cruz, M.; Fehling, H. J.; Kaer, L. V.; Monaco, J. J.; Colbert, R. A. Immunoproteasome assembly: cooperative incorporation of interferon gamma (IFN-gamma)-inducible subunits. J. Exp. Med., 1998, 187, 97-104.
-
(1998)
J. Exp. Med
, vol.187
, pp. 97-104
-
-
Griffin, T.A.1
Nandi, D.2
Cruz, M.3
Fehling, H.J.4
Kaer, L.V.5
Monaco, J.J.6
Colbert, R.A.7
-
35
-
-
0032971227
-
Degradation of cell proteins and the generation of MHC class I- presented peptides
-
Rock, K. L.; Goldberg, A. L. Degradation of cell proteins and the generation of MHC class I- presented peptides. Annu. Rev. Immunol., 1999, 17, 739-779.
-
(1999)
Annu. Rev. Immunol
, vol.17
, pp. 739-779
-
-
Rock, K.L.1
Goldberg, A.L.2
-
36
-
-
34247190754
-
LMP2-specific inhibitors: Novel chemical genetic tools for proteasome biology
-
Ho, Y. K.; Bargagna-Mohan, P.; Mohan, R.; Kim, K. B. LMP2-specific inhibitors: Novel chemical genetic tools for proteasome biology. Chem. Biol., 2007, 14, 419-430.
-
(2007)
Chem. Biol
, vol.14
, pp. 419-430
-
-
Ho, Y.K.1
Bargagna-Mohan, P.2
Mohan, R.3
Kim, K.B.4
-
37
-
-
0028241569
-
Displacement of housekeeping proteasome subunits by MHCencoded LMPs: A newly discovered mechanism for modulating the multicatalytic proteinase complex
-
Fruh, K.; Gossen, M.; Wang, K.; Bujard, H.; Peterson, P. A.; Yang, Y. Displacement of housekeeping proteasome subunits by MHCencoded LMPs: a newly discovered mechanism for modulating the multicatalytic proteinase complex. EMBO J., 1994, 13, 3236-3244.
-
(1994)
EMBO J
, vol.13
, pp. 3236-3244
-
-
Fruh, K.1
Gossen, M.2
Wang, K.3
Bujard, H.4
Peterson, P.A.5
Yang, Y.6
-
38
-
-
33947659939
-
20S proteasome and its inhibitors: Crystallographic knowledge for drug development
-
Borissenko, L.; Groll, M. 20S proteasome and its inhibitors: crystallographic knowledge for drug development. Chem. Rev., 2007, 107, 687-717.
-
(2007)
Chem. Rev
, vol.107
, pp. 687-717
-
-
Borissenko, L.1
Groll, M.2
-
39
-
-
0034988832
-
Accessory proteins that control the assembly of MHC molecules with peptides
-
Van Kaer, L. Accessory proteins that control the assembly of MHC molecules with peptides. Immunol. Res., 2001, 23, 205-214.
-
(2001)
Immunol. Res
, vol.23
, pp. 205-214
-
-
van Kaer, L.1
-
40
-
-
0027991677
-
MHC class I expression in mice lacking the proteasome subunit LMP-7
-
Fehling, H. J.; Swat, W.; Laplace, C.; Kuhn, R.; Rajewsky, K.; Muller, U.; von Boehmer, H. MHC class I expression in mice lacking the proteasome subunit LMP-7. Science, 1994, 265, 1234-1237.
-
(1994)
Science
, vol.265
, pp. 1234-1237
-
-
Fehling, H.J.1
Swat, W.2
Laplace, C.3
Kuhn, R.4
Rajewsky, K.5
Muller, U.6
von Boehmer, H.7
-
41
-
-
0029347127
-
LMP2+proteasomes are required for the presentation of specific antigens to cytotoxic T lymphocytes
-
Sibille, C.; Gould, K. G.; Willard-Gallo, K.; Thomson, S.; Rivett, A. J.; Powis, S.; Butcher, G. W.; De Baetselier, P. LMP2+proteasomes are required for the presentation of specific antigens to cytotoxic T lymphocytes. Curr. Biol., 1995, 5, 923-930.
-
(1995)
Curr. Biol
, vol.5
, pp. 923-930
-
-
Sibille, C.1
Gould, K.G.2
Willard-Gallo, K.3
Thomson, S.4
Rivett, A.J.5
Powis, S.6
Butcher, G.W.7
de Baetselier, P.8
-
42
-
-
33646884677
-
An altered T cell repertoire in MECL-1-deficient mice
-
Basler, M.; Moebius, J.; Elenich, L.; Groettrup, M.; Monaco, J. J. An altered T cell repertoire in MECL-1-deficient mice. J. Immunol., 2006, 176, 6665-6672.
-
(2006)
J. Immunol
, vol.176
, pp. 6665-6672
-
-
Basler, M.1
Moebius, J.2
Elenich, L.3
Groettrup, M.4
Monaco, J.J.5
-
43
-
-
0029940895
-
20S proteasome from LMP7 knock out mice reveals altered proteolytic activities and cleavage site preferences
-
Stohwasser, R.; Kuckelkorn, U.; Kraft, R.; Kostka, S.; Kloetzel, P. M. 20S proteasome from LMP7 knock out mice reveals altered proteolytic activities and cleavage site preferences. FEBS Lett., 1996, 383, 109-113.
-
(1996)
FEBS Lett
, vol.383
, pp. 109-113
-
-
Stohwasser, R.1
Kuckelkorn, U.2
Kraft, R.3
Kostka, S.4
Kloetzel, P.M.5
-
44
-
-
0035806246
-
-
Chen, W.; Norbury, C. C.; Cho, Y.; Yewdell, J. W.; Bennink, J. R. Immunoproteasomes shape immunodominance hierarchies of antiviral CD8(+) T cells at the levels of T cell repertoire and presentation of viral antigens. J. Exp. Med., 2001, 193, 1319-1326.
-
(2001)
Immunoproteasomes Shape Immunodominance Hierarchies of Antiviral CD8(+) T Cells At the Levels of T Cell Repertoire and Presentation of Viral Antigens
, vol.193
, pp. 1319-1326
-
-
Chen, W.1
Norbury, C.C.2
Cho, Y.3
Yewdell, J.W.4
Bennink, J.R.5
-
45
-
-
21544452226
-
Immunoproteasomes: Regulating the regulator
-
Yewdell, J. W. Immunoproteasomes: regulating the regulator. Proc. Natl. Acad. Sci. USA, 2005, 102, 9089-9090.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 9089-9090
-
-
Yewdell, J.W.1
-
46
-
-
33646053214
-
T cells lacking immunoproteasome subunits MECL-1 and LMP7 hyperproliferate in response to polyclonal mitogens
-
Caudill, C. M.; Jayarapu, K.; Elenich, L.; Monaco, J. J.; Colbert, R. A.; Griffin, T. A. T cells lacking immunoproteasome subunits MECL-1 and LMP7 hyperproliferate in response to polyclonal mitogens. J. Immunol., 2006, 176, 4075-4082.
-
(2006)
J. Immunol
, vol.176
, pp. 4075-4082
-
-
Caudill, C.M.1
Jayarapu, K.2
Elenich, L.3
Monaco, J.J.4
Colbert, R.A.5
Griffin, T.A.6
-
47
-
-
0026442415
-
Proteasome subunits encoded in the MHC are not generally required for the processing of peptides bound by MHC class I molecules
-
Arnold, D.; Driscoll, J.; Androlewicz, M.; Hughes, E.; Cresswell, P.; Spies, T. Proteasome subunits encoded in the MHC are not generally required for the processing of peptides bound by MHC class I molecules. Nature, 1992, 360, 171-174.
-
(1992)
Nature
, vol.360
, pp. 171-174
-
-
Arnold, D.1
Driscoll, J.2
Androlewicz, M.3
Hughes, E.4
Cresswell, P.5
Spies, T.6
-
48
-
-
0028346277
-
MHCencoded proteasome subunits LMP2 and LMP7 are not required for efficient antigen presentation
-
Yewdell, J.; Lapham, C.; Bacik, I.; Spies, T.; Bennink, J. MHCencoded proteasome subunits LMP2 and LMP7 are not required for efficient antigen presentation. J. Immunol., 1994, 152, 1163-1170.
-
(1994)
J. Immunol
, vol.152
, pp. 1163-1170
-
-
Yewdell, J.1
Lapham, C.2
Bacik, I.3
Spies, T.4
Bennink, J.5
-
49
-
-
0026480535
-
Proteasome subunits encoded by the major histocompatibility complex are not essential for antigen presentation
-
Momburg, F.; Ortiz-Navarrete, V.; Neefjes, J.; Goulmy, E.; van de Wal, Y.; Spits, H.; Powis, S. J.; Butcher, G. W.; Howard, J. C.; Walden, P et al. Proteasome subunits encoded by the major histocompatibility complex are not essential for antigen presentation. Nature, 1992, 360, 174-177.
-
(1992)
Nature
, vol.360
, pp. 174-177
-
-
Momburg, F.1
Ortiz-Navarrete, V.2
Neefjes, J.3
Goulmy, E.4
van de Wal, Y.5
Spits, H.6
Powis, S.J.7
Butcher, G.W.8
Howard, J.C.9
Walden, P.10
-
50
-
-
0036402152
-
Proteasome function and protein oxidation in the aged retina
-
Louie, J. L.; Kapphahn, R. J.; Ferrington, D. A. Proteasome function and protein oxidation in the aged retina. Exp. Eye Res., 2002, 75, 271-284.
-
(2002)
Exp. Eye Res
, vol.75
, pp. 271-284
-
-
Louie, J.L.1
Kapphahn, R.J.2
Ferrington, D.A.3
-
51
-
-
45249092950
-
Immunoproteasome responds to injury in the retina and brain
-
Ferrington, D. A.; Hussong, S. A.; Roehrich, H.; Kapphahn, R. J.; Kavanaugh, S. M.; Heuss, N. D.; Gregerson, D. S. Immunoproteasome responds to injury in the retina and brain. J. Neurochem., 2008, 106, 158-169.
-
(2008)
J. Neurochem
, vol.106
, pp. 158-169
-
-
Ferrington, D.A.1
Hussong, S.A.2
Roehrich, H.3
Kapphahn, R.J.4
Kavanaugh, S.M.5
Heuss, N.D.6
Gregerson, D.S.7
-
52
-
-
33847160728
-
Transformation of the proteasome with agerelated macular degeneration
-
Ethen, C. M.; Hussong, S. A.; Reilly, C.; Feng, X.; Olsen, T. W.; Ferrington, D. A. Transformation of the proteasome with agerelated macular degeneration. FEBS Lett., 2007, 581, 885-890.
-
(2007)
FEBS Lett
, vol.581
, pp. 885-890
-
-
Ethen, C.M.1
Hussong, S.A.2
Reilly, C.3
Feng, X.4
Olsen, T.W.5
Ferrington, D.A.6
-
53
-
-
33645788632
-
A structural model of 20S immunoproteasomes: Effect of LMP2 codon 60 polymorphism on expression, activity, intracellular localisation and insight into the regulatory mechanisms
-
Mishto, M.; Santoro, A.; Bellavista, E.; Sessions, R.; Textoris-Taube, K.; Dal Piaz, F.; Carrard, G.; Forti, K.; Salvioli, S.; Friguet, B.; Kloetzel, P. M.; Rivett, A. J.; Franceschi, C. A structural model of 20S immunoproteasomes: effect of LMP2 codon 60 polymorphism on expression, activity, intracellular localisation and insight into the regulatory mechanisms. Biol. Chem., 2006, 387, 417-429.
-
(2006)
Biol. Chem
, vol.387
, pp. 417-429
-
-
Mishto, M.1
Santoro, A.2
Bellavista, E.3
Sessions, R.4
Textoris-Taube, K.5
dal Piaz, F.6
Carrard, G.7
Forti, K.8
Salvioli, S.9
Friguet, B.10
Kloetzel, P.M.11
Rivett, A.J.12
Franceschi, C.13
-
54
-
-
72949119404
-
Critical role for the immunoproteasome subunit LMP7 in the resistance of mice to Toxoplasma gondii infection
-
Tu, L.; Moriya, C.; Imai, T.; Ishida, H.; Tetsutani, K.; Duan, X.; Murata, S.; Tanaka, K.; Shimokawa, C.; Hisaeda, H.; Himeno, K. Critical role for the immunoproteasome subunit LMP7 in the resistance of mice to Toxoplasma gondii infection. Eur. J. Immunol., 2009, 39, 3385-3394.
-
(2009)
Eur. J. Immunol
, vol.39
, pp. 3385-3394
-
-
Tu, L.1
Moriya, C.2
Imai, T.3
Ishida, H.4
Tetsutani, K.5
Duan, X.6
Murata, S.7
Tanaka, K.8
Shimokawa, C.9
Hisaeda, H.10
Himeno, K.11
-
55
-
-
0034770294
-
Characterization of membraneassociated proteasomes in WB rat liver epithelial cells
-
Khan, M. T.; Joseph, S. K. Characterization of membraneassociated proteasomes in WB rat liver epithelial cells. Arch. Biochem. Biophys., 2001, 385, 99-107.
-
(2001)
Arch. Biochem. Biophys
, vol.385
, pp. 99-107
-
-
Khan, M.T.1
Joseph, S.K.2
-
56
-
-
2342588229
-
Genomic analysis of the host response to hepatitis B virus infection
-
Wieland, S.; Thimme, R.; Purcell, R. H.; Chisari, F. V. Genomic analysis of the host response to hepatitis B virus infection. Proc. Natl. Acad. Sci. USA, 2004, 101, 6669-6674.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 6669-6674
-
-
Wieland, S.1
Thimme, R.2
Purcell, R.H.3
Chisari, F.V.4
-
57
-
-
33846083832
-
Role of immunoproteasome catalytic subunits in the immune response to hepatitis B virus
-
Robek, M. D.; Garcia, M. L.; Boyd, B. S.; Chisari, F. V. Role of immunoproteasome catalytic subunits in the immune response to hepatitis B virus. J. Virol., 2007, 81, 483-491.
-
(2007)
J. Virol
, vol.81
, pp. 483-491
-
-
Robek, M.D.1
Garcia, M.L.2
Boyd, B.S.3
Chisari, F.V.4
-
58
-
-
0037105392
-
Regulation of immunoproteasome subunit expression in vivo following pathogenic fungal infection
-
Barton, L. F.; Cruz, M.; Rangwala, R.; Deepe, G. S., Jr.; Monaco, J. J. Regulation of immunoproteasome subunit expression in vivo following pathogenic fungal infection. J. Immunol., 2002, 169, 3046-3052.
-
(2002)
J. Immunol
, vol.169
, pp. 3046-3052
-
-
Barton, L.F.1
Cruz, M.2
Rangwala, R.3
Deepe Jr., G.S.4
Monaco, J.J.5
-
59
-
-
33750597617
-
Virus-induced type I IFN stimulates generation of immunoproteasomes at the site of infection
-
Shin, E. C.; Seifert, U.; Kato, T.; Rice, C. M.; Feinstone, S. M.; Kloetzel, P. M.; Rehermann, B. Virus-induced type I IFN stimulates generation of immunoproteasomes at the site of infection. J. Clin. Invest., 2006, 116, 3006-3014.
-
(2006)
J. Clin. Invest
, vol.116
, pp. 3006-3014
-
-
Shin, E.C.1
Seifert, U.2
Kato, T.3
Rice, C.M.4
Feinstone, S.M.5
Kloetzel, P.M.6
Rehermann, B.7
-
60
-
-
33744819439
-
Intracellular HIV-1 Tat protein represses constitutive LMP2 transcription increasing proteasome activity by interfering with the binding of IRF-1 to STAT1
-
Remoli, A. L.; Marsili, G.; Perrotti, E.; Gallerani, E.; Ilari, R.; Nappi, F.; Cafaro, A.; Ensoli, B.; Gavioli, R.; Battistini, A. Intracellular HIV-1 Tat protein represses constitutive LMP2 transcription increasing proteasome activity by interfering with the binding of IRF-1 to STAT1. Biochem. J.,2006, 396, 371-380.
-
(2006)
Biochem. J
, vol.396
, pp. 371-380
-
-
Remoli, A.L.1
Marsili, G.2
Perrotti, E.3
Gallerani, E.4
Ilari, R.5
Nappi, F.6
Cafaro, A.7
Ensoli, B.8
Gavioli, R.9
Battistini, A.10
-
61
-
-
37849043864
-
The Tat protein broadens T cell responses directed to the HIV-1 antigens Gag and Env: Implications for the design of new vaccination strategies against AIDS
-
Gavioli, R.; Cellini, S.; Castaldello, A.; Voltan, R.; Gallerani, E.; Gagliardoni, F.; Fortini, C.; Cofano, E. B.; Triulzi, C.; Cafaro, A.; Srivastava, I.; Barnett, S.; Caputo, A.; Ensoli, B. The Tat protein broadens T cell responses directed to the HIV-1 antigens Gag and Env: implications for the design of new vaccination strategies against AIDS. Vaccine, 2008, 26, 727-737.
-
(2008)
Vaccine
, vol.26
, pp. 727-737
-
-
Gavioli, R.1
Cellini, S.2
Castaldello, A.3
Voltan, R.4
Gallerani, E.5
Gagliardoni, F.6
Fortini, C.7
Cofano, E.B.8
Triulzi, C.9
Cafaro, A.10
Srivastava, I.11
Barnett, S.12
Caputo, A.13
Ensoli, B.14
-
62
-
-
76149101291
-
Persistent hijacking of brain proteasomes in HIV-associated dementia
-
Nguyen, T. P.; Soukup, V. M.; Gelman, B. B. Persistent hijacking of brain proteasomes in HIV-associated dementia. Am. J. Pathol., 2010, 176, 893-902.
-
(2010)
Am. J. Pathol
, vol.176
, pp. 893-902
-
-
Nguyen, T.P.1
Soukup, V.M.2
Gelman, B.B.3
-
63
-
-
33646471043
-
Immunoproteasome subunit LMP2 expression is deregulated in Sjogren's syndrome but not in other autoimmune disorders
-
Krause, S.; Kuckelkorn, U.; Dorner, T.; Burmester, G. R.; Feist, E.; Kloetzel, P. M. Immunoproteasome subunit LMP2 expression is deregulated in Sjogren's syndrome but not in other autoimmune disorders. Ann. Rheum. Dis., 2006, 65, 1021-1027.
-
(2006)
Ann. Rheum. Dis
, vol.65
, pp. 1021-1027
-
-
Krause, S.1
Kuckelkorn, U.2
Dorner, T.3
Burmester, G.R.4
Feist, E.5
Kloetzel, P.M.6
-
64
-
-
72449155236
-
Expression of proteasomal immunosubunit β1i Is dysregulated in inflammatory infiltrates of minor salivary glands in sjogren's syndrome
-
Morawietz, L.; Martinez-Gamboa, L.; Scheffler, S.; Hausdorf, G.; Dankof, A.; Kuckelkorn, U.; Doerner, T.; Egerer, K.; Burmester, G. R.; Faustman, D. L.; Feist, E. Expression of proteasomal immunosubunit β1i Is dysregulated in inflammatory infiltrates of minor salivary glands in sjogren's syndrome. J. Rheumatol., 2009, 36, 2694-2703.
-
(2009)
J. Rheumatol
, vol.36
, pp. 2694-2703
-
-
Morawietz, L.1
Martinez-Gamboa, L.2
Scheffler, S.3
Hausdorf, G.4
Dankof, A.5
Kuckelkorn, U.6
Doerner, T.7
Egerer, K.8
Burmester, G.R.9
Faustman, D.L.10
Feist, E.11
-
65
-
-
33646474855
-
Tissue-specific up-regulation of the proteasome subunit beta5i (LMP7) in Sjogren's syndrome
-
Egerer, T.; Martinez-Gamboa, L.; Dankof, A.; Stuhlmuller, B.; Dorner, T.; Krenn, V.; Egerer, K.; Rudolph, P. E.; Burmester, G. R.; Feist, E. Tissue-specific up-regulation of the proteasome subunit beta5i (LMP7) in Sjogren's syndrome. Arthritis Rheum., 2006, 54, 1501-1508.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 1501-1508
-
-
Egerer, T.1
Martinez-Gamboa, L.2
Dankof, A.3
Stuhlmuller, B.4
Dorner, T.5
Krenn, V.6
Egerer, K.7
Rudolph, P.E.8
Burmester, G.R.9
Feist, E.10
-
66
-
-
33845306274
-
Proteasome-mediated degradation of IkappaBalpha and processing of p105 in Crohn disease and ulcerative colitis
-
Visekruna, A.; Joeris, T.; Seidel, D.; Kroesen, A.; Loddenkemper, C.; Zeitz, M.; Kaufmann, S. H.; Schmidt-Ullrich, R.; Steinhoff, U. Proteasome-mediated degradation of IkappaBalpha and processing of p105 in Crohn disease and ulcerative colitis. J. Clin. Invest., 2006, 116, 3195-3203.
-
(2006)
J. Clin. Invest
, vol.116
, pp. 3195-3203
-
-
Visekruna, A.1
Joeris, T.2
Seidel, D.3
Kroesen, A.4
Loddenkemper, C.5
Zeitz, M.6
Kaufmann, S.H.7
Schmidt-Ullrich, R.8
Steinhoff, U.9
-
67
-
-
33847768010
-
Enhanced intestinal expression of the proteasome subunit low molecular mass polypeptide 2 in patients with inflammatory bowel disease
-
Fitzpatrick, L. R.; Small, J. S.; Poritz, L. S.; McKenna, K. J.; Koltun, W. A. Enhanced intestinal expression of the proteasome subunit low molecular mass polypeptide 2 in patients with inflammatory bowel disease. Dis. Colon Rectum, 2007, 50, 337-348.
-
(2007)
Dis. Colon Rectum
, vol.50
, pp. 337-348
-
-
Fitzpatrick, L.R.1
Small, J.S.2
Poritz, L.S.3
McKenna, K.J.4
Koltun, W.A.5
-
68
-
-
33748433821
-
Dextran sulfate sodium-induced colitis is associated with enhanced low molecular mass polypeptide 2 (LMP2) expression and is attenuated in LMP2 knockout mice
-
Fitzpatrick, L. R.; Khare, V.; Small, J. S.; Koltun, W. A. Dextran sulfate sodium-induced colitis is associated with enhanced low molecular mass polypeptide 2 (LMP2) expression and is attenuated in LMP2 knockout mice. Dig. Dis. Sci., 2006, 51, 1269-1276.
-
(2006)
Dig. Dis. Sci
, vol.51
, pp. 1269-1276
-
-
Fitzpatrick, L.R.1
Khare, V.2
Small, J.S.3
Koltun, W.A.4
-
69
-
-
2442651500
-
Proteasomal expression, induction of immunoproteasome subunits, and local MHC class I presentation in myofibrillar myopathy and inclusion body myositis
-
Ferrer, I.; Martin, B.; Castano, J. G.; Lucas, J. J.; Moreno, D.; Olive, M. Proteasomal expression, induction of immunoproteasome subunits, and local MHC class I presentation in myofibrillar myopathy and inclusion body myositis. J. Neuropathol. Exp. Neurol., 2004, 63, 484-498.
-
(2004)
J. Neuropathol. Exp. Neurol
, vol.63
, pp. 484-498
-
-
Ferrer, I.1
Martin, B.2
Castano, J.G.3
Lucas, J.J.4
Moreno, D.5
Olive, M.6
-
70
-
-
68149163335
-
Cardiovascular inflammation and lesion cell apoptosis: A novel connection via the interferon-inducible immunoproteasome
-
Yang, Z.; Gagarin, D.; St Laurent, G., 3rd; Hammell, N.; Toma, I.; Hu, C. A.; Iwasa, A.; McCaffrey, T. A. Cardiovascular inflammation and lesion cell apoptosis: a novel connection via the interferon-inducible immunoproteasome. Arterioscler. Thromb. Vasc. Biol., 2009, 29, 1213-1219.
-
(2009)
Arterioscler. Thromb. Vasc. Biol
, vol.29
, pp. 1213-1219
-
-
Yang, Z.1
Gagarin, D.2
Laurent St. III, G.3
Hammell, N.4
Toma, I.5
Hu, C.A.6
Iwasa, A.7
McCaffrey, T.A.8
-
71
-
-
0347064159
-
Neuronal induction of the immunoproteasome in Huntington's disease
-
Diaz-Hernandez, M.; Hernandez, F.; Martin-Aparicio, E.; Gomez-Ramos, P.; Moran, M. A.; Castano, J. G.; Ferrer, I.; Avila, J.; Lucas, J. J. Neuronal induction of the immunoproteasome in Huntington's disease. J. Neurosci., 2003, 23, 11653-11661.
-
(2003)
J. Neurosci
, vol.23
, pp. 11653-11661
-
-
Diaz-Hernandez, M.1
Hernandez, F.2
Martin-Aparicio, E.3
Gomez-Ramos, P.4
Moran, M.A.5
Castano, J.G.6
Ferrer, I.7
Avila, J.8
Lucas, J.J.9
-
72
-
-
13944283365
-
Enhanced induction of the immunoproteasome by interferon gamma in neurons expressing mutant Huntingtin
-
Diaz-Hernandez, M.; Martin-Aparicio, E.; Avila, J.; Hernandez, F.; Lucas, J. J. Enhanced induction of the immunoproteasome by interferon gamma in neurons expressing mutant Huntingtin. Neurotox. Res., 2004, 6, 463-468.
-
(2004)
Neurotox. Res
, vol.6
, pp. 463-468
-
-
Diaz-Hernandez, M.1
Martin-Aparicio, E.2
Avila, J.3
Hernandez, F.4
Lucas, J.J.5
-
73
-
-
27744461250
-
Immunoproteasome and LMP2 polymorphism in aged and Alzheimer's disease brains
-
Mishto, M.; Bellavista, E.; Santoro, A.; Stolzing, A.; Ligorio, C.; Nacmias, B.; Spazzafumo, L.; Chiappelli, M.; Licastro, F.; Sorbi, S.; Pession, A.; Ohm, T.; Grune, T.; Franceschi, C. Immunoproteasome and LMP2 polymorphism in aged and Alzheimer's disease brains. Neurobiol. Aging, 2006, 27, 54-66.
-
(2006)
Neurobiol. Aging
, vol.27
, pp. 54-66
-
-
Mishto, M.1
Bellavista, E.2
Santoro, A.3
Stolzing, A.4
Ligorio, C.5
Nacmias, B.6
Spazzafumo, L.7
Chiappelli, M.8
Licastro, F.9
Sorbi, S.10
Pession, A.11
Ohm, T.12
Grune, T.13
Franceschi, C.14
-
74
-
-
27744601821
-
Non-neuronal induction of immunoproteasome subunits in an ALS model: Possible mediation by cytokines
-
Puttaparthi, K.; Elliott, J. L. Non-neuronal induction of immunoproteasome subunits in an ALS model: possible mediation by cytokines. Exp. Neurol., 2005, 196, 441-451.
-
(2005)
Exp. Neurol
, vol.196
, pp. 441-451
-
-
Puttaparthi, K.1
Elliott, J.L.2
-
75
-
-
57649232173
-
Functional alterations of the ubiquitin-proteasome system in motor neurons of a mouse model of familial amyotrophic lateral sclerosis
-
Cheroni, C.; Marino, M.; Tortarolo, M.; Veglianese, P.; De Biasi, S.; Fontana, E.; Zuccarello, L. V.; Maynard, C. J.; Dantuma, N. P.; Bendotti, C. Functional alterations of the ubiquitin-proteasome system in motor neurons of a mouse model of familial amyotrophic lateral sclerosis. Hum. Mol. Genet., 2009, 18, 82-96.
-
(2009)
Hum. Mol. Genet
, vol.18
, pp. 82-96
-
-
Cheroni, C.1
Marino, M.2
Tortarolo, M.3
Veglianese, P.4
de Biasi, S.5
Fontana, E.6
Zuccarello, L.V.7
Maynard, C.J.8
Dantuma, N.P.9
Bendotti, C.10
-
76
-
-
34250621825
-
Assessing the role of immuno-proteasomes in a mouse model of familial ALS
-
Puttaparthi, K.; Van Kaer, L.; Elliott, J. L. Assessing the role of immuno-proteasomes in a mouse model of familial ALS. Exp. Neurol., 2007, 206, 53-58.
-
(2007)
Exp. Neurol
, vol.206
, pp. 53-58
-
-
Puttaparthi, K.1
van Kaer, L.2
Elliott, J.L.3
-
77
-
-
70350686895
-
Down-regulation of HLA class I antigen-processing machinery components in esophageal squamous cell carcinomas: Association with disease progression
-
Liu, Q.; Hao, C.; Su, P.; Shi, J. Down-regulation of HLA class I antigen-processing machinery components in esophageal squamous cell carcinomas: association with disease progression. Scand. J. Gastroenterol., 2009, 44, 960-969.
-
(2009)
Scand. J. Gastroenterol
, vol.44
, pp. 960-969
-
-
Liu, Q.1
Hao, C.2
Su, P.3
Shi, J.4
-
78
-
-
0034843611
-
Prognostic significance of immuno-proteosome subunit expression in patients with renal-cell carcinoma: A preliminary study
-
Murakami, Y.; Kanda, K.; Yokota, K.; Kanayama, H.; Kagawa, S. Prognostic significance of immuno-proteosome subunit expression in patients with renal-cell carcinoma: a preliminary study. Mol. Urol., 2001, 5, 113-119.
-
(2001)
Mol. Urol
, vol.5
, pp. 113-119
-
-
Murakami, Y.1
Kanda, K.2
Yokota, K.3
Kanayama, H.4
Kagawa, S.5
-
79
-
-
4344644908
-
High frequency of functionally active Melan-a-specific T cells in a patient with progressive immunoproteasome-deficient melanoma
-
Meidenbauer, N.; Zippelius, A.; Pittet, M. J.; Laumer, M.; Vogl, S.; Heymann, J.; Rehli, M.; Seliger, B.; Schwarz, S.; Le Gal, F. A.; Dietrich, P. Y.; Andreesen, R.; Romero, P.; Mackensen, A. High frequency of functionally active Melan-a-specific T cells in a patient with progressive immunoproteasome-deficient melanoma. Cancer Res., 2004, 64, 6319-6326.
-
(2004)
Cancer Res
, vol.64
, pp. 6319-6326
-
-
Meidenbauer, N.1
Zippelius, A.2
Pittet, M.J.3
Laumer, M.4
Vogl, S.5
Heymann, J.6
Rehli, M.7
Seliger, B.8
Schwarz, S.9
Le Gal, F.A.10
Dietrich, P.Y.11
Andreesen, R.12
Romero, P.13
Mackensen, A.14
-
80
-
-
0035650718
-
Deficient expression of components of the MHC class I antigen processing machinery in human cervical carcinoma
-
Ritz, U.; Momburg, F.; Pilch, H.; Huber, C.; Maeurer, M. J.; Seliger, B. Deficient expression of components of the MHC class I antigen processing machinery in human cervical carcinoma. Int. J. Oncol., 2001, 19, 1211-1220.
-
(2001)
Int. J. Oncol
, vol.19
, pp. 1211-1220
-
-
Ritz, U.1
Momburg, F.2
Pilch, H.3
Huber, C.4
Maeurer, M.J.5
Seliger, B.6
-
81
-
-
17644413210
-
Defects in the human leukocyte antigen class I antigen processing machinery in head and neck squamous cell carcinoma: Association with clinical outcome
-
Meissner, M.; Reichert, T. E.; Kunkel, M.; Gooding, W.; Whiteside, T. L.; Ferrone, S.; Seliger, B. Defects in the human leukocyte antigen class I antigen processing machinery in head and neck squamous cell carcinoma: association with clinical outcome. Clin. Cancer Res., 2005, 11, 2552-2560.
-
(2005)
Clin. Cancer Res
, vol.11
, pp. 2552-2560
-
-
Meissner, M.1
Reichert, T.E.2
Kunkel, M.3
Gooding, W.4
Whiteside, T.L.5
Ferrone, S.6
Seliger, B.7
-
82
-
-
24744456734
-
Effects of PS-341 on the activity and composition of proteasomes in multiple myeloma cells
-
Altun, M.; Galardy, P. J.; Shringarpure, R.; Hideshima, T.; LeBlanc, R.; Anderson, K. C.; Ploegh, H. L.; Kessler, B. M. Effects of PS-341 on the activity and composition of proteasomes in multiple myeloma cells. Cancer Res., 2005, 65, 7896-7901.
-
(2005)
Cancer Res
, vol.65
, pp. 7896-7901
-
-
Altun, M.1
Galardy, P.J.2
Shringarpure, R.3
Hideshima, T.4
Leblanc, R.5
Anderson, K.C.6
Ploegh, H.L.7
Kessler, B.M.8
-
83
-
-
36049051956
-
Enhanced expression of interferon-gamma-induced antigen-processing machinery components in a spontaneously occurring cancer
-
Cerruti, F.; Martano, M.; Petterino, C.; Bollo, E.; Morello, E.; Bruno, R.; Buracco, P.; Cascio, P. Enhanced expression of interferon-gamma-induced antigen-processing machinery components in a spontaneously occurring cancer. Neoplasia, 2007, 9, 960-969.
-
(2007)
Neoplasia
, vol.9
, pp. 960-969
-
-
Cerruti, F.1
Martano, M.2
Petterino, C.3
Bollo, E.4
Morello, E.5
Bruno, R.6
Buracco, P.7
Cascio, P.8
-
84
-
-
41049094957
-
Proteasome modulators: Essential chemical genetic tools for understanding human diseases
-
Wehenkel, M.; Hong, J. T.; Kim, K. B. Proteasome modulators: essential chemical genetic tools for understanding human diseases. Mol. Biosyst., 2008, 4, 280-286.
-
(2008)
Mol. Biosyst
, vol.4
, pp. 280-286
-
-
Wehenkel, M.1
Hong, J.T.2
Kim, K.B.3
-
85
-
-
0034864799
-
Proteasome inhibitors: From research tools to drug candidates
-
Kisselev, A. F.; Goldberg, A. L. Proteasome inhibitors: from research tools to drug candidates. Chem. Biol., 2001, 8, 739-758.
-
(2001)
Chem. Biol
, vol.8
, pp. 739-758
-
-
Kisselev, A.F.1
Goldberg, A.L.2
-
86
-
-
33748075461
-
Proteasome inhibitor drugs on the rise
-
Joazeiro, C. A.; Anderson, K. C.; Hunter, T. Proteasome inhibitor drugs on the rise. Cancer Res., 2006, 66, 7840-7842.
-
(2006)
Cancer Res
, vol.66
, pp. 7840-7842
-
-
Joazeiro, C.A.1
Anderson, K.C.2
Hunter, T.3
-
87
-
-
34447116376
-
Antitumor activity of PR-171, a novel irreversible inhibitor of the proteasome
-
Demo, S. D.; Kirk, C. J.; Aujay, M. A.; Buchholz, T. J.; Dajee, M.; Ho, M. N.; Jiang, J.; Laidig, G. J.; Lewis, E. R.; Parlati, F.; Shenk, K. D.; Smyth, M. S.; Sun, C. M.; Vallone, M. K.; Woo, T. M.; Molineaux, C. J.; Bennett, M. K. Antitumor activity of PR-171, a novel irreversible inhibitor of the proteasome. Cancer Res., 2007, 67, 6383-6391.
-
(2007)
Cancer Res
, vol.67
, pp. 6383-6391
-
-
Demo, S.D.1
Kirk, C.J.2
Aujay, M.A.3
Buchholz, T.J.4
Dajee, M.5
Ho, M.N.6
Jiang, J.7
Laidig, G.J.8
Lewis, E.R.9
Parlati, F.10
Shenk, K.D.11
Smyth, M.S.12
Sun, C.M.13
Vallone, M.K.14
Woo, T.M.15
Molineaux, C.J.16
Bennett, M.K.17
-
88
-
-
33750209537
-
A novel proteasome inhibitor NPI-0052 as an anticancer therapy
-
Chauhan, D.; Hideshima, T.; Anderson, K. C. A novel proteasome inhibitor NPI-0052 as an anticancer therapy. Br. J. Cancer, 2006, 95, 961-965.
-
(2006)
Br. J. Cancer
, vol.95
, pp. 961-965
-
-
Chauhan, D.1
Hideshima, T.2
Anderson, K.C.3
-
89
-
-
33947196412
-
Phase I/II study of bortezomib plus docetaxel in patients with advanced androgen-independent prostate cancer
-
Dreicer, R.; Petrylak, D.; Agus, D.; Webb, I.; Roth, B. Phase I/II study of bortezomib plus docetaxel in patients with advanced androgen-independent prostate cancer. Clin. Cancer Res., 2007, 13, 1208-1215.
-
(2007)
Clin. Cancer Res
, vol.13
, pp. 1208-1215
-
-
Dreicer, R.1
Petrylak, D.2
Agus, D.3
Webb, I.4
Roth, B.5
-
90
-
-
1842866995
-
Proteasome inhibitor PS-341 down-regulates prostate-specific antigen (PSA) and induces growth arrest and apoptosis of androgen-dependent human prostate cancer LNCaP cells
-
Ikezoe, T.; Yang, Y.; Saito, T.; Koeffler, H. P.; Taguchi, H. Proteasome inhibitor PS-341 down-regulates prostate-specific antigen (PSA) and induces growth arrest and apoptosis of androgen-dependent human prostate cancer LNCaP cells. Cancer Sci., 2004, 95, 271-275.
-
(2004)
Cancer Sci
, vol.95
, pp. 271-275
-
-
Ikezoe, T.1
Yang, Y.2
Saito, T.3
Koeffler, H.P.4
Taguchi, H.5
-
91
-
-
65649139708
-
Design and synthesis of an orally bioavailable and selective peptide epoxyketone proteasome inhibitor (PR-047)
-
Zhou, H. J.; Aujay, M. A.; Bennett, M. K.; Dajee, M.; Demo, S. D.; Fang, Y.; Ho, M. N.; Jiang, J.; Kirk, C. J.; Laidig, G. J.; Lewis, E. R.; Lu, Y.; Muchamuel, T.; Parlati, F.; Ring, E.; Shenk, K. D.; Shields, J.; Shwonek, P. J.; Stanton, T.; Sun, C. M.; Sylvain, C.; Woo, T. M.; Yang, J. Design and synthesis of an orally bioavailable and selective peptide epoxyketone proteasome inhibitor (PR-047). J. Med. Chem., 2009, 52(9),3028-3038.
-
(2009)
J. Med. Chem
, vol.52
, Issue.9
, pp. 3028-3038
-
-
Zhou, H.J.1
Aujay, M.A.2
Bennett, M.K.3
Dajee, M.4
Demo, S.D.5
Fang, Y.6
Ho, M.N.7
Jiang, J.8
Kirk, C.J.9
Laidig, G.J.10
Lewis, E.R.11
Lu, Y.12
Muchamuel, T.13
Parlati, F.14
Ring, E.15
Shenk, K.D.16
Shields, J.17
Shwonek, P.J.18
Stanton, T.19
Sun, C.M.20
Sylvain, C.21
Woo, T.M.22
Yang, J.23
more..
-
92
-
-
50249092779
-
Development of proteasome inhibitors in oncology and autoimmune diseases
-
Bennett, M. K.; Kirk, C. J. Development of proteasome inhibitors in oncology and autoimmune diseases. Curr. Opin. Drug Discov. Devel., 2008, 11, 616-625.
-
(2008)
Curr. Opin. Drug Discov. Devel
, vol.11
, pp. 616-625
-
-
Bennett, M.K.1
Kirk, C.J.2
-
93
-
-
0343262654
-
Crystal structure of epoxomicin:20S proteasome reveals a molecular basis for selectivity of α',β'-epoxyketone proteasome inhibitors
-
Groll, M.; Kim, K. B.; Kairies, N.; Huber, R.; Crews, C. M. Crystal structure of epoxomicin:20S proteasome reveals a molecular basis for selectivity of α',β'-epoxyketone proteasome inhibitors. J. Am. Chem. Soc., 2000, 122, 1237-1238.
-
(2000)
J. Am. Chem. Soc
, vol.122
, pp. 1237-1238
-
-
Groll, M.1
Kim, K.B.2
Kairies, N.3
Huber, R.4
Crews, C.M.5
-
94
-
-
83455232300
-
-
U. S. Patent7,642,369, January 5
-
Kim, K. B.; Ho, Y. K. Epoxyketone-based immunoproteasome inhibitors. U. S. Patent7,642,369, January 5, 2010.
-
(2010)
Epoxyketone-based Immunoproteasome Inhibitors
-
-
Kim, K.B.1
Ho, Y.K.2
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