메뉴 건너뛰기




Volumn 107, Issue 6, 2006, Pages 2507-2516

AMAPK/HNRPK pathway controls BCR/ABL oncogenic potential by regulating MYC mRNA translation

Author keywords

[No Author keywords available]

Indexed keywords

BCR ABL PROTEIN; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN K; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MYC PROTEIN; CD34 ANTIGEN; HNRPK PROTEIN, HUMAN; MYC PROTEIN, HUMAN; RIBONUCLEOPROTEIN;

EID: 33644755496     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2005-09-3732     Document Type: Article
Times cited : (174)

References (55)
  • 1
    • 2542441665 scopus 로고    scopus 로고
    • The BCR-ABL story: Bench to bedside and back
    • Wong S, Witte ON. The BCR-ABL story: bench to bedside and back. Annu Rev Immunol. 2004;22:247-306.
    • (2004) Annu Rev Immunol , vol.22 , pp. 247-306
    • Wong, S.1    Witte, O.N.2
  • 2
    • 2542500611 scopus 로고    scopus 로고
    • The biology of CML blast crisis
    • Calabretta B, Perrotti D. The biology of CML blast crisis. Blood. 2004;103:4010-4022.
    • (2004) Blood , vol.103 , pp. 4010-4022
    • Calabretta, B.1    Perrotti, D.2
  • 3
    • 0033614446 scopus 로고    scopus 로고
    • Chronic myeloid leukemia
    • Sawyers CL. Chronic myeloid leukemia. N Engl J Med. 1999;340:1330-1340.
    • (1999) N Engl J Med , vol.340 , pp. 1330-1340
    • Sawyers, C.L.1
  • 4
    • 2942648711 scopus 로고    scopus 로고
    • Signal transduction pathways in Bcr-Abl transformed cells
    • Arlinghaus R, Sun T. Signal transduction pathways in Bcr-Abl transformed cells. Cancer Treat Res. 2004;119:239-270.
    • (2004) Cancer Treat Res , vol.119 , pp. 239-270
    • Arlinghaus, R.1    Sun, T.2
  • 6
    • 0141508021 scopus 로고    scopus 로고
    • Bcr-Abl kinase modulates the translation regulators ribosomal protein S6 and 4E-BP1 in chronic myelogenous leukemia cells via the mammalian target of rapamycin
    • Ly C, Arechiga AF, Melo JV, Walsh CM, Ong ST. Bcr-Abl kinase modulates the translation regulators ribosomal protein S6 and 4E-BP1 in chronic myelogenous leukemia cells via the mammalian target of rapamycin. Cancer Res. 2003;63:5716-5722.
    • (2003) Cancer Res , vol.63 , pp. 5716-5722
    • Ly, C.1    Arechiga, A.F.2    Melo, J.V.3    Walsh, C.M.4    Ong, S.T.5
  • 8
    • 0029133211 scopus 로고
    • Increase of bcrabl chimeric mRNA expression in tumor cells of patients with chronic myeloid leukemia precedes disease progression
    • Gaiger A, Henn T, Horth E, et al. Increase of bcrabl chimeric mRNA expression in tumor cells of patients with chronic myeloid leukemia precedes disease progression. Blood. 1995;86:2371-2378.
    • (1995) Blood , vol.86 , pp. 2371-2378
    • Gaiger, A.1    Henn, T.2    Horth, E.3
  • 9
    • 0033884287 scopus 로고    scopus 로고
    • The amount of BCR-ABL fusion transcripts detected by the real-time quantitative polymerase chain reaction method in patients with Philadelphia chromosome positive chronic myeloid leukemia correlates with the disease stage
    • Elmaagacli AH, Beelen DW, Opalka B, Seeber S, Schaefer UW. The amount of BCR-ABL fusion transcripts detected by the real-time quantitative polymerase chain reaction method in patients with Philadelphia chromosome positive chronic myeloid leukemia correlates with the disease stage. Ann Hematol. 2000;79:424-431.
    • (2000) Ann Hematol , vol.79 , pp. 424-431
    • Elmaagacli, A.H.1    Beelen, D.W.2    Opalka, B.3    Seeber, S.4    Schaefer, U.W.5
  • 10
    • 3943088431 scopus 로고    scopus 로고
    • Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML
    • Jamieson CH, Ailles LE, Dylla SJ, et al. Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML. N Engl J Med. 2004;351:657-667.
    • (2004) N Engl J Med , vol.351 , pp. 657-667
    • Jamieson, C.H.1    Ailles, L.E.2    Dylla, S.J.3
  • 11
    • 0036340784 scopus 로고    scopus 로고
    • BCR-ABL suppresses C/EBPalpha expression through inhibitory action of hnRNP E2
    • Perrotti D, Cesi V, Trotta R, et al. BCR-ABL suppresses C/EBPalpha expression through inhibitory action of hnRNP E2. Nat Genet. 2002;30:48-58.
    • (2002) Nat Genet , vol.30 , pp. 48-58
    • Perrotti, D.1    Cesi, V.2    Trotta, R.3
  • 12
    • 0012956142 scopus 로고    scopus 로고
    • BCR/ABL activates mdm2 mRNA translation via the la antigen
    • Trotta R, Vignudelli T, Candini O, et al. BCR/ABL activates mdm2 mRNA translation via the La antigen. Cancer Cell. 2003;3:145-160.
    • (2003) Cancer Cell , vol.3 , pp. 145-160
    • Trotta, R.1    Vignudelli, T.2    Candini, O.3
  • 13
    • 0036223676 scopus 로고    scopus 로고
    • The poly(C)-binding proteins: A multiplicity of functions and a search for mechanisms
    • Makeyev AV, Liebhaber SA. The poly(C)-binding proteins: a multiplicity of functions and a search for mechanisms. RNA. 2002;8:265-278.
    • (2002) RNA , vol.8 , pp. 265-278
    • Makeyev, A.V.1    Liebhaber, S.A.2
  • 14
  • 15
    • 0029671095 scopus 로고    scopus 로고
    • Trans-Activation by the hnRNP K protein involves an increase in RNA synthesis from the reporter genes
    • Lee MH, Mori S, Raychaudhuri P. trans-Activation by the hnRNP K protein involves an increase in RNA synthesis from the reporter genes. J Biol Chem. 1996;271:3420-3427.
    • (1996) J Biol Chem , vol.271 , pp. 3420-3427
    • Lee, M.H.1    Mori, S.2    Raychaudhuri, P.3
  • 17
    • 0028329195 scopus 로고
    • An RNA-binding protein associated with Src through its SH2 and SH3 domains in mitosis
    • Taylor SJ, Shalloway D. An RNA-binding protein associated with Src through its SH2 and SH3 domains in mitosis. Nature. 1994;368:867-871.
    • (1994) Nature , vol.368 , pp. 867-871
    • Taylor, S.J.1    Shalloway, D.2
  • 18
    • 0028894021 scopus 로고
    • Association of the vav proto-oncogene product with poly(rC)-specific RNA-binding proteins
    • Bustelo XR, Suen KL, Michael WM, Dreyfuss G, Barbacid M. Association of the vav proto-oncogene product with poly(rC)-specific RNA-binding proteins. Mol Cell Biol. 1995;15:1324-1332.
    • (1995) Mol Cell Biol , vol.15 , pp. 1324-1332
    • Bustelo, X.R.1    Suen, K.L.2    Michael, W.M.3    Dreyfuss, G.4    Barbacid, M.5
  • 19
    • 0032563806 scopus 로고    scopus 로고
    • Mutagenic analysis of Vav reveals that an intact SH3 domain is required for transformation
    • Groysman M, Nagano M, Shaanan B, Katzav S. Mutagenic analysis of Vav reveals that an intact SH3 domain is required for transformation. Oncogene. 1998;17:1597-1606.
    • (1998) Oncogene , vol.17 , pp. 1597-1606
    • Groysman, M.1    Nagano, M.2    Shaanan, B.3    Katzav, S.4
  • 20
    • 0033591364 scopus 로고    scopus 로고
    • Regulated interaction of protein kinase Cdelta with the heterogeneous nuclear ribonucleoprotein K protein
    • Schullery DS, Ostrowski J, Denisenko ON, et al. Regulated interaction of protein kinase Cdelta with the heterogeneous nuclear ribonucleoprotein K protein. J Biol Chem. 1999;274:15101-15109.
    • (1999) J Biol Chem , vol.274 , pp. 15101-15109
    • Schullery, D.S.1    Ostrowski, J.2    Denisenko, O.N.3
  • 21
    • 0035095885 scopus 로고    scopus 로고
    • ERK phosphorylation drives cytoplasmic accumulation of hnRNP-K and inhibition of mRNA translation
    • Habelhah H, Shah K, Huang L, et al. ERK phosphorylation drives cytoplasmic accumulation of hnRNP-K and inhibition of mRNA translation. Nat Cell Biol. 2001;3:325-330.
    • (2001) Nat Cell Biol , vol.3 , pp. 325-330
    • Habelhah, H.1    Shah, K.2    Huang, L.3
  • 22
    • 0036276219 scopus 로고    scopus 로고
    • c-Src-mediated phosphorylation of hnRNP K drives translational activation of specifically silenced mRNAs
    • Ostareck-Lederer A, Ostareck DH, Cans C, et al. c-Src-mediated phosphorylation of hnRNP K drives translational activation of specifically silenced mRNAs. Mol Cell Biol. 2002;22:4535-4543.
    • (2002) Mol Cell Biol , vol.22 , pp. 4535-4543
    • Ostareck-Lederer, A.1    Ostareck, D.H.2    Cans, C.3
  • 23
    • 0345549480 scopus 로고    scopus 로고
    • Members of the poly (rC) binding protein family stimulate the activity of the c-myc internal ribosome entry segment in vitro and in vivo
    • Evans JR, Mitchell SA, Spriggs KA, et al. Members of the poly (rC) binding protein family stimulate the activity of the c-myc internal ribosome entry segment in vitro and in vivo. Oncogene. 2003;22:8012-8020.
    • (2003) Oncogene , vol.22 , pp. 8012-8020
    • Evans, J.R.1    Mitchell, S.A.2    Spriggs, K.A.3
  • 24
    • 0036124398 scopus 로고    scopus 로고
    • hnRNP A1 nucleocytoplasmic shuttling activity is required for normal myelopoiesis and BCR/ABL leukemogenesis
    • Iervolino A, Santilli G, Trotta R, et al. hnRNP A1 nucleocytoplasmic shuttling activity is required for normal myelopoiesis and BCR/ABL leukemogenesis. Mol Cell Biol. 2002;22:2255-2266.
    • (2002) Mol Cell Biol , vol.22 , pp. 2255-2266
    • Iervolino, A.1    Santilli, G.2    Trotta, R.3
  • 25
    • 0036351379 scopus 로고    scopus 로고
    • Ribonomics: Identifying mRNA subsets in mRNP complexes using antibodies to RNA-binding proteins and genomic arrays
    • Tenenbaum SA, Lager PJ, Carson CC, Keene JD. Ribonomics: identifying mRNA subsets in mRNP complexes using antibodies to RNA-binding proteins and genomic arrays. Methods. 2002;26:191-198.
    • (2002) Methods , vol.26 , pp. 191-198
    • Tenenbaum, S.A.1    Lager, P.J.2    Carson, C.C.3    Keene, J.D.4
  • 26
    • 0033525882 scopus 로고    scopus 로고
    • Expression of c-Myc in response to colony-stimulating factor-1 requires mitogen-activated protein kinase kinase-1
    • Cheng M, Wang D, Roussel MF. Expression of c-Myc in response to colony-stimulating factor-1 requires mitogen-activated protein kinase kinase-1. J Biol Chem. 1999;274:6553-6558.
    • (1999) J Biol Chem , vol.274 , pp. 6553-6558
    • Cheng, M.1    Wang, D.2    Roussel, M.F.3
  • 27
    • 0026788001 scopus 로고
    • Dominant negative MYC blocks transformation by ABL oncogenes
    • Sawyers CL, Callahan W, Witte ON. Dominant negative MYC blocks transformation by ABL oncogenes. Cell. 1992;70:901-910.
    • (1992) Cell , vol.70 , pp. 901-910
    • Sawyers, C.L.1    Callahan, W.2    Witte, O.N.3
  • 28
    • 0027851829 scopus 로고
    • Interleukin-3 and p210 BCR/ABL activate both unique and overlapping pathways of signal transduction in a factor-dependent myeloid cell line
    • Matulonis U, Salgia R, Okuda K, Druker B, Griffin JD. Interleukin-3 and p210 BCR/ABL activate both unique and overlapping pathways of signal transduction in a factor-dependent myeloid cell line. Exp Hematol. 1993;21:1460-1466.
    • (1993) Exp Hematol , vol.21 , pp. 1460-1466
    • Matulonis, U.1    Salgia, R.2    Okuda, K.3    Druker, B.4    Griffin, J.D.5
  • 29
    • 0030725775 scopus 로고    scopus 로고
    • The Bcr-Abl tyrosine kinase activates mitogenic signaling pathways and stimulates G1-to-S phase transition in hematopoietic cells
    • Cortez D, Reuther G, Pendergast AM. The Bcr-Abl tyrosine kinase activates mitogenic signaling pathways and stimulates G1-to-S phase transition in hematopoietic cells. Oncogene. 1997;15:2333-2342.
    • (1997) Oncogene , vol.15 , pp. 2333-2342
    • Cortez, D.1    Reuther, G.2    Pendergast, A.M.3
  • 30
    • 0029768861 scopus 로고    scopus 로고
    • Antisense oligodeoxynucleotide combination therapy of primary chronic myelogenous leukemia blast crisis in SCID mice
    • Skorski T, Nieborowska-Skorska M, Wlodarski P, Zon G, Iozzo RV, Calabretta B. Antisense oligodeoxynucleotide combination therapy of primary chronic myelogenous leukemia blast crisis in SCID mice. Blood. 1996;88:1005-1012.
    • (1996) Blood , vol.88 , pp. 1005-1012
    • Skorski, T.1    Nieborowska-Skorska, M.2    Wlodarski, P.3    Zon, G.4    Iozzo, R.V.5    Calabretta, B.6
  • 31
    • 25444457705 scopus 로고    scopus 로고
    • Dose-dependent effects of Bcr-Abl in cell line models of different stages of chronic myeloid leukemia
    • Barnes DJ, Schultheis B, Adedeji S, Melo JV. Dose-dependent effects of Bcr-Abl in cell line models of different stages of chronic myeloid leukemia. Oncogene. 2005;24:6432-6440.
    • (2005) Oncogene , vol.24 , pp. 6432-6440
    • Barnes, D.J.1    Schultheis, B.2    Adedeji, S.3    Melo, J.V.4
  • 32
    • 0032479980 scopus 로고    scopus 로고
    • TLS/FUS, a pro-oncogene involved in multiple chromosomal translocations, is a novel regulator of BCR/ABLmediated leukemogenesis
    • Perrotti D, Bonatti S, Trotta R, et al. TLS/FUS, a pro-oncogene involved in multiple chromosomal translocations, is a novel regulator of BCR/ABLmediated leukemogenesis. EMBO J. 1998;17:4442-4455.
    • (1998) EMBO J , vol.17 , pp. 4442-4455
    • Perrotti, D.1    Bonatti, S.2    Trotta, R.3
  • 33
    • 27644569730 scopus 로고    scopus 로고
    • The tumor suppressor PP2A is functionally inactivated in blast crisis CML through the inhibitory activity of the BCR/ABL-regulated SET protein
    • Neviani P, Santhanam R, Trotta R, et al. The tumor suppressor PP2A is functionally inactivated in blast crisis CML through the inhibitory activity of the BCR/ABL-regulated SET protein. Cancer Cell. 2005;5:355-368.
    • (2005) Cancer Cell , vol.5 , pp. 355-368
    • Neviani, P.1    Santhanam, R.2    Trotta, R.3
  • 34
    • 0035971083 scopus 로고    scopus 로고
    • Growth factors regulate heterogeneous nuclear ribonucleoprotein K expression and function
    • Mandal M, Vadlamudi R, Nguyen D, et al. Growth factors regulate heterogeneous nuclear ribonucleoprotein K expression and function. J Biol Chem. 2001;276:9699-9704.
    • (2001) J Biol Chem , vol.276 , pp. 9699-9704
    • Mandal, M.1    Vadlamudi, R.2    Nguyen, D.3
  • 35
    • 1642291861 scopus 로고    scopus 로고
    • Differential protein synthesis and expression levels in normal and neoplastic human prostate cells and their regulation by type I and II interferons
    • Nagano K, Masters JR, Akpan A, et al. Differential protein synthesis and expression levels in normal and neoplastic human prostate cells and their regulation by type I and II interferons. Oncogene. 2004;23:1693-1703.
    • (2004) Oncogene , vol.23 , pp. 1693-1703
    • Nagano, K.1    Masters, J.R.2    Akpan, A.3
  • 36
    • 4444363680 scopus 로고    scopus 로고
    • Comparative proteomic analysis of all-trans-retinoic acid treatment reveals systematic posttranscriptional control mechanisms in acute promyelocytic leukemia
    • Harris MN, Ozpolat B, Abdi F, et al. Comparative proteomic analysis of all-trans-retinoic acid treatment reveals systematic posttranscriptional control mechanisms in acute promyelocytic leukemia. Blood. 2004;104:1314-1323.
    • (2004) Blood , vol.104 , pp. 1314-1323
    • Harris, M.N.1    Ozpolat, B.2    Abdi, F.3
  • 37
    • 14644412367 scopus 로고    scopus 로고
    • A proteomic investigation into etoposide chemo-resistance of neuroblastoma cell lines
    • Urbani A, Poland J, Bernardini S, et al. A proteomic investigation into etoposide chemo-resistance of neuroblastoma cell lines. Proteomics. 2005;5:796-804.
    • (2005) Proteomics , vol.5 , pp. 796-804
    • Urbani, A.1    Poland, J.2    Bernardini, S.3
  • 38
    • 0029029421 scopus 로고
    • C-RAF-1 serine/threonine kinase is required in BCR/ABL-dependent and normal hematopoiesis
    • Skorski T, Nieborowska-Skorska M, Szczylik C, et al. C-RAF-1 serine/threonine kinase is required in BCR/ABL-dependent and normal hematopoiesis. Cancer Res. 1995;55:2275-2278.
    • (1995) Cancer Res , vol.55 , pp. 2275-2278
    • Skorski, T.1    Nieborowska-Skorska, M.2    Szczylik, C.3
  • 39
    • 1842474838 scopus 로고    scopus 로고
    • BCR/ABL kinase inhibition by imatinib mesylate enhances MAP kinase activity in chronic myelogenous leukemia CD34+ cells
    • Chu S, Holtz M, Gupta M, Bhatia R. BCR/ABL kinase inhibition by imatinib mesylate enhances MAP kinase activity in chronic myelogenous leukemia CD34+ cells. Blood. 2004;103:3167-3174.
    • (2004) Blood , vol.103 , pp. 3167-3174
    • Chu, S.1    Holtz, M.2    Gupta, M.3    Bhatia, R.4
  • 40
    • 0035803494 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of Grb2 by Bcr/Abl and epidermal growth factor receptor: A novel regulatory mechanism for tyrosine kinase signaling
    • Li S, Couvillon AD, Brasher BB, Van Etten RA. Tyrosine phosphorylation of Grb2 by Bcr/Abl and epidermal growth factor receptor: a novel regulatory mechanism for tyrosine kinase signaling. EMBO J. 2001;20:6793-6804.
    • (2001) EMBO J , vol.20 , pp. 6793-6804
    • Li, S.1    Couvillon, A.D.2    Brasher, B.B.3    Van Etten, R.A.4
  • 41
    • 0030978415 scopus 로고    scopus 로고
    • The K nuclear shuttling domain: A novel signal for nuclear import and nuclear export in the hnRNP K protein
    • Michael WM, Eder PS, Dreyfuss G. The K nuclear shuttling domain: a novel signal for nuclear import and nuclear export in the hnRNP K protein. EMBO J. 1997;16:3587-3598.
    • (1997) EMBO J , vol.16 , pp. 3587-3598
    • Michael, W.M.1    Eder, P.S.2    Dreyfuss, G.3
  • 42
    • 0035817343 scopus 로고    scopus 로고
    • p62(dok), a negative regulator of Ras and mitogen-activated protein kinase (MAPK) activity, opposes leukemogenesis by p210(bcr-abl)
    • Di Cristofano A, Niki M, Zhao M, et al. p62(dok), a negative regulator of Ras and mitogen-activated protein kinase (MAPK) activity, opposes leukemogenesis by p210(bcr-abl). J Exp Med. 2001;194:275-284.
    • (2001) J Exp Med , vol.194 , pp. 275-284
    • Di Cristofano, A.1    Niki, M.2    Zhao, M.3
  • 43
    • 0031982854 scopus 로고    scopus 로고
    • The SH3 domain contributes to BCR/ABLdependent leukemogenesis in vivo: Role in adhesion, invasion, and homing
    • Skorski T, Nieborowska-Skorska M, Wlodarski P, et al. The SH3 domain contributes to BCR/ABLdependent leukemogenesis in vivo: role in adhesion, invasion, and homing. Blood. 1998;91:406-418.
    • (1998) Blood , vol.91 , pp. 406-418
    • Skorski, T.1    Nieborowska-Skorska, M.2    Wlodarski, P.3
  • 44
    • 0023217510 scopus 로고
    • Molecular characteristics of chronic myelogenous leukemia in blast crisis
    • Blick M, Romero P, Talpaz M, et al. Molecular characteristics of chronic myelogenous leukemia in blast crisis. Cancer Genet Cytogenet. 1987;27:349-356.
    • (1987) Cancer Genet Cytogenet , vol.27 , pp. 349-356
    • Blick, M.1    Romero, P.2    Talpaz, M.3
  • 45
    • 0027070651 scopus 로고
    • Abnormal regulation of the myc gene in myeloid leukemia
    • Gopal V, Kadam P, Preisler H, et al. Abnormal regulation of the myc gene in myeloid leukemia. Med Oncol Tumor Pharmacother. 1992;9:139-147.
    • (1992) Med Oncol Tumor Pharmacother , vol.9 , pp. 139-147
    • Gopal, V.1    Kadam, P.2    Preisler, H.3
  • 47
    • 0029850508 scopus 로고    scopus 로고
    • Blastic transformation of p53-deficient bone marrow cells by p210bcr/abl tyrosine kinase
    • U S A
    • Skorski T, Nieborowska-Skorska M, Wlodarski P, et al. Blastic transformation of p53-deficient bone marrow cells by p210bcr/abl tyrosine kinase. Proc Natl Acad Sci U S A. 1996;93:13137-13142.
    • (1996) Proc Natl Acad Sci , vol.93 , pp. 13137-13142
    • Skorski, T.1    Nieborowska-Skorska, M.2    Wlodarski, P.3
  • 48
    • 0027312772 scopus 로고
    • The role of myc in transformation by BCR-ABL
    • Sawyers CL. The role of myc in transformation by BCR-ABL. Leuk Lymphoma. 1993;11(suppl 1):45-46.
    • (1993) Leuk Lymphoma , vol.11 , Issue.1 SUPPL. , pp. 45-46
    • Sawyers, C.L.1
  • 49
    • 0037126385 scopus 로고    scopus 로고
    • Jak2 is involved in c-Myc induction by Bcr-Abl
    • Xie S, Lin H, Sun T, Arlinghaus RB. Jak2 is involved in c-Myc induction by Bcr-Abl. Oncogene. 2002;21:7137-7146.
    • (2002) Oncogene , vol.21 , pp. 7137-7146
    • Xie, S.1    Lin, H.2    Sun, T.3    Arlinghaus, R.B.4
  • 50
    • 0028980342 scopus 로고
    • Structural and signaling requirements for BCR-ABL-mediated transformation and inhibition of apoptosis
    • Cortez D, Kadlec L, Pendergast AM. Structural and signaling requirements for BCR-ABL-mediated transformation and inhibition of apoptosis. Mol Cell Biol. 1995;15:5531-5541.
    • (1995) Mol Cell Biol , vol.15 , pp. 5531-5541
    • Cortez, D.1    Kadlec, L.2    Pendergast, A.M.3
  • 51
    • 0023772690 scopus 로고
    • Effect of differentiation-inducing agents on oncogene expression in a chronic myelogenous leukemia cell line
    • Eisbruch A, Blick M, Evinger-Hodges MJ, et al. Effect of differentiation-inducing agents on oncogene expression in a chronic myelogenous leukemia cell line. Cancer. 1988;62:1171-1178.
    • (1988) Cancer , vol.62 , pp. 1171-1178
    • Eisbruch, A.1    Blick, M.2    Evinger-Hodges, M.J.3
  • 52
    • 18244404089 scopus 로고    scopus 로고
    • Characterization of stage progression in chronic myeloid leukemia by DNA microarray with purified hematopoietic stem cells
    • Ohmine K, Ota J, Ueda M, et al. Characterization of stage progression in chronic myeloid leukemia by DNA microarray with purified hematopoietic stem cells. Oncogene. 2001;20:8249-8257.
    • (2001) Oncogene , vol.20 , pp. 8249-8257
    • Ohmine, K.1    Ota, J.2    Ueda, M.3
  • 53
    • 0038799721 scopus 로고    scopus 로고
    • Genomic imbalances in CML blast crisis: 8q24.12-q24.13 segment identified as a common region of over-representation
    • Gribble SM, Reid AG, Roberts I, Grace C, Green AR, Nacheva EP. Genomic imbalances in CML blast crisis: 8q24.12-q24.13 segment identified as a common region of over-representation. Genes Chromosomes Cancer. 2003;37:346-358.
    • (2003) Genes Chromosomes Cancer , vol.37 , pp. 346-358
    • Gribble, S.M.1    Reid, A.G.2    Roberts, I.3    Grace, C.4    Green, A.R.5    Nacheva, E.P.6
  • 54
    • 0030063410 scopus 로고    scopus 로고
    • Detection of c-myc oncogene amplification in a CML blastic phase patient with double minute chromosomes
    • Karasawa M, Okamoto K, Maehara T, et al. Detection of c-myc oncogene amplification in a CML blastic phase patient with double minute chromosomes. Leuk Res. 1996;20:85-91.
    • (1996) Leuk Res , vol.20 , pp. 85-91
    • Karasawa, M.1    Okamoto, K.2    Maehara, T.3
  • 55
    • 4244081197 scopus 로고    scopus 로고
    • The molecular biology of chronic myeloid leukaemia
    • Melo JV. The molecular biology of chronic myeloid leukaemia. Leukemia. 1996;10:751-756.
    • (1996) Leukemia , vol.10 , pp. 751-756
    • Melo, J.V.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.