Decreased intracellular GABA levels contribute to spinal cord stimulation-induced analgesia in rats suffering from painful peripheral neuropathy: The role of KCC2 and GABA A receptor-mediated inhibition

Neurochemistry International

Volumn 60, Issue 1, 2012, Pages 21-30

  Janssen, S P ^a   Gerard, S ^a   Raijmakers, M E ^a   Truin, M ^a   Van Kleef, M ^a   Joosten, E A ^a  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Chronic neuropathic pain; GABA; GABA A receptor; KCC2; Rats; Spinal cord stimulation

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR STIMULATING AGENT; MEMBRANE PROTEIN; POTASSIUM CHLORIDE COTRANSPORTER; PROTEIN POTASSIUM CHLORIDE COTRANSPORTER 2; UNCLASSIFIED DRUG;

ANALGESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; IMMUNOCOMPETENT CELL; IMMUNOFLUORESCENCE; MALE; NERVE LIGATION; NONHUMAN; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL; PROTEIN CEREBROSPINAL FLUID LEVEL; PROTEIN EXPRESSION; RAT; SCIATIC NERVE; SPINAL CORD DORSAL HORN; SPINAL CORD STIMULATION; SPRAGUE DAWLEY RAT;

ANALGESIA; ANIMALS; CHRONIC PAIN; DISEASE MODELS, ANIMAL; ELECTRIC STIMULATION THERAPY; GAMMA-AMINOBUTYRIC ACID; MALE; NEURAL INHIBITION; NEURALGIA; PERIPHERAL NERVOUS SYSTEM DISEASES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; SPINAL CORD; SYMPORTERS; SYNAPTIC TRANSMISSION;

ANIMALIA; RATTUS;

EID: 83455211125     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2011.11.006     Document Type: Article

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