Transcutaneous electrical nerve stimulation on Yongquan acupoint reduces CFA-induced thermal hyperalgesia of rats via down-regulation of ERK2 phosphorylation and c-Fos expression

Anatomical Record

Volumn 293, Issue 7, 2010, Pages 1207-1213

  Yang, Lin ^a   Yang, Lianxue ^a   Gao, Xiulai ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

c Fos; CFA induced inflammatory pain; ERK1 2; TENS application

Indexed keywords

FREUND ADJUVANT; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN C FOS;

ADOLESCENT; AMYGDALOID NUCLEUS; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENE EXPRESSION REGULATION; HYPERALGESIA; HYPERSENSITIVITY; INTERVERTEBRAL DISK HERNIA; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SOMATOSENSORY CORTEX; THERMAL STIMULATION; TRANSCUTANEOUS NERVE STIMULATION; ACUPUNCTURE; ANALGESIA; ANIMAL; CHEMICALLY INDUCED; DRUG EFFECTS; ENZYMOLOGY; FOOT; METABOLISM; PHOSPHORYLATION; POSTERIOR HORN CELL; WISTAR RAT;

ACUPUNCTURE POINTS; ANALGESIA; ANIMALS; DOWN-REGULATION; FOOT; FREUND'S ADJUVANT; HYPERALGESIA; MALE; MITOGEN-ACTIVATED PROTEIN KINASE 1; PHOSPHORYLATION; POSTERIOR HORN CELLS; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, WISTAR; TRANSCUTANEOUS ELECTRIC NERVE STIMULATION;

EID: 77954566066     PISSN: 19328486     EISSN: 19328494     Source Type: Journal    
DOI: 10.1002/ar.21157     Document Type: Article

References (36)

1. Abbadie C, Besson JM, Calvino B. 1994. C-Fos expression in the spinal-cord and pain-related symptoms induced by chronic arthritis in the rat are prevented by pretreatment with freund adjuvant. J Neurosci 14:5865-5871.
2. Bellavance LL, Beitz AJ. 1996. Altered c-fos expression in the parabrachial nucleus in a rodent model of CFA-induced peripheral inflammation. J Comp Neurol 366:431-447.
3. Bjordal JM, Johnson MI, Ljunggreen AE. 2003. Transcutaneous electrical nerve stimulation (TENS) can reduce postoperative analgesic consumption. A meta-analysis with assessment of optimal treatment parameters for postoperative pain. Eur J Pain 7:181-188.
4. Buchel C, Dolan RJ. 2000. Classical fear conditioning in functional neuroimaging. Curr Opin Neurobiol 10:219-223. (Pubitemid 30201115)
5. Carlsson C. 2002. Acupuncture mechanisms for clinically relevant long-term effects - reconsideration and a hypothesis. Acupunct Med 20:82-99. (Pubitemid 34975975)
6. Chao AS, Chao A, Wang TH, Chang YC, Peng HH, Chang SD, Chao A, Chang CJ, Lai CH, Wong AM. 2007. Pain relief by applying transcutaneous electrical nerve stimulation (TENS) on acupuncture points during the first stage of labor: a randomized double-blind placebo-controlled trial. Pain 127:214-220.
7. Cruz CD, Ferreira D, McMahon SB, Cruz F. 2007. The activation of the ERK pathway contributes to the spinal c-fos expression observed after noxious bladder stimultion. Somatoens Mot Res 24:15-20.
8. Dhond RP, Kettner N, Napadow V. 2007. Do the neural correlates of acupuncture and placebo effects differ? Pain 128:8-12.
9. Fields HL. 2000. Pain modulation: expectation, opioid analgesia and virtual pain. Prog Brain Res 122:245-253.
10. Garrison DW, Foreman RD. 1994. Decreased activity of spontaneous and noxiously evoked dorsal horn cells during transcutaneous electrical nerve stimulation (TENS). Pain 58:309-315.
11. Giles PA, Trezise DJ, King AE. 2007. Differential activation of protein kinases in the dorsal horn in vitro of normal and inflamed rats by group I metabotropic glutamate receptor subtypes. Neuropharmacology 53:58-70.
12. Guo ZL, Moazzami AR, Longhurst JC. 2004. Electroacupuncture induces c-Fos expression in the rostral ventrolateral medulla and periaqueductal gray in cats: relation to opioid containing neurons. Brain Res 1030:103-115.
13. Han JS. 2003. Acupuncture: neuropeptide release produced by electrical stimulation of different frequencies. Trends Neurosci 26:17-22.
14. Hargreaves K, Dubner R, Brown F, Flores C, Joris J. 1988. A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain 32:77-88.
15. Hay CH, Trevethick MA, Wheeldon A, Bowers JS, de Belleroche JS. 1997. The potential role of spinal cord cyclooxygenase-2 in the development of Freund's complete adjuvant-induced changes in hyperalgesia and allodynia. Neuroscience 78:843-850.
16. Ji RR, Baba H, Brenner GJ, Woolf CJ. 1999. Nociceptive-specific activation of ERK in spinal neurons contributes to pain hypersensitivity. Nat Neurosci 2:1114-1119.
17. Ji RR, Befort K, Brenner GJ, Woolf CJ. 2002. ERK MAP kinase activation in superficial spinal cord neurons induces prodynorphin and NK-1 upregulation and contributes to persistent inflammatory pain hypersensitivity. J Neurosci 22:478-485.
18. Jiang J, Yang W, Huang P, Bu X, Zhang N, Li J. 2009. Increased phosphorylation of Ets-like transcription factor-1 in neurons of hypoxic preconditioned mice. Neurochem Res 34:1443-1450.
19. Kawasaki Y, Kohno T, Zhuang ZY, Brenner GJ, Wang H, Van Der MC, Befort K, Woolf CJ, Ji RR. 2004. Ionotropic and metabotropic receptors, protein kinase A, protein kinase C, and Src contribute to C-fiber-induced ERK activation and cAMP response element-binding protein phosphorylation in dorsal horn neurons, leading to central sensitization. J Neurosci 24:8310-8321.
20. Kim JH, Chung JY, Kwon YK, Kim KJ, Yang CH, Hahm DH, Lee HJ, Pyun KH, Shim I. 2005. Acupuncture reduces alcohol withdrawal syndrome and c-Fos expression in rat brain. Am J Chin Med 33:887-896.
21. Kim JH, Kim HK, Park YI, Sohn IC, Choi DO, Kim MS, Park BR. 2006. Moxibustion at ST36 alleviates pain in complete Freund's adjuvant-induced arthritic rats. Am J Chin Med 34:57-67.
22. Kwon YB, Han HJ, Beitz AJ, Lee JH. 2004. Bee venom acupoint stimulation increases Fos expression in catecholaminergic neurons in the rat brain. Mol Cells 17:329-333.
23. Lu R, Liu M. 1991. Clinical application of single acupoint for treatment. J Tradit Chin Med 11:284-285.
24. McCarson KE, Krause JE. 1994. NK-1 and NK-3 type tachykinin receptor mRNA expression in the rat spinal cord dorsal horn is increased during adjuvant or formalin-induced nociception. J Neurosci 14:712-720.
25. Napadow V, Kettner N, Liu J, Li M, Kwong KK, Vangel M, Makris N, Audette J, Hui KK. 2007. Hypothalamus and amygdala response to acupuncture stimuli in Carpal Tunnel Syndrome. Pain 130:254-266. (Pubitemid 46977116)
26. Petrovic P, Carlsson K, Petersson KM, Hansson P, Ingvar M. 2004. Context-dependent deactivation of the amygdala during pain. J Cogn Neurosci 16:1289-1301.
27. Petrovic P, Petersson KM, Ghatan PH, Stone-Elander S, Ingvar M. 2000. Pain-related cerebral activation is altered by a distracting cognitive task. Pain 85:19-30.
28. Petrovic P, Petersson KM, Hansson P, Ingvar M. 2002. A regression analysis study of the primary somatosensory cortex during pain10. Neuroimage 16:1142-1150.
29. Qin W, Tian J, Bai L, Pan X, Yang L, Chen P, Dai J, Ai L, Zhao B, Gong Q, Wang W, von Deneen KM, Liu Y. 2008. FMRI connectivity analysis of acupuncture effects on an amygdala-associated brain network. Mol Pain 4:1-17.
30. Roh DH, Kim HW, Yoon SY, Kang SY, Kwon YB, Cho KH, Han HJ, Ryu YH, Choi SM, Lee HJ, Beitz AJ, Lee JH. 2006. Bee venom injection significantly reduces nociceptive behavior in the mouse formalin test via capsaicin-insensitive afferents. J Pain 7:500-512.
31. Wang TT, Yuan WL, Ke Q, Song XB, Zhou X, Kang Y, Zhang HT, Lin Y, Hu YL, Feng ZT, Wu LL, Zhou XF. 2006. Effects of electro-acupuncture on the expression of c-jun and c-fos in spared dorsal root ganglion and associated spinal laminae following removal of adjacent dorsal root ganglia in cats. Neuroscience 140:1169-1176.
32. Woolf CJ. 2007. Central sensitization: uncovering the relation between pain and plasticity. Anesthesiology 106:864-867.
33. Woolf CJ, Salter MW. 2000. Neuronal plasticity: increasing the gain in pain. Science 288:1765-1769.
34. Zhang N, Gao G, Bu X, Han S, Fang L, Li J. 2007. Neuron-specific phosphorylation of c-Jun N-terminal kinase increased in the brain of hypoxic preconditioned mice. Neurosci Lett 423:219-224. (Pubitemid 47285484)
35. Zhang YQ, Ji GC, Wu GC, Zhao ZQ. 2003. Kynurenic acid enhances electroacupuncture analgesia in normal and carrageenan-injected rats. Brain Res 966:300-307.
36. Zhuang ZY, Gerner P, Woolf CJ, Ji RR. 2005. ERK is sequentially activated in neurons, microglia, and astrocytes by spinal nerve ligation and contributes to mechanical allodynia in this neuropathic pain model. Pain 114:149-159.