Muscarinic receptor subtypes and signalling involved in the attenuation of isoprenaline-induced rat urinary bladder relaxation

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 384, Issue 6, 2011, Pages 555-563

  Witte, Lambertus P W ^a   De Haas, Noach ^a   Mammen, Mathai ^b   Stangeland, Eric L ^b   Steinfeld, Tod ^b   Aiyar, Jayashree ^b   Michel, Martin C ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b THERAVANCE INC   (United States)

Author keywords

Adrenoceptor; M 2 muscarinic receptor; M 3 muscarinic receptor; Relaxation; THRX 182087; Urinary bladder

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; CHELERYTHRINE; ISOPRENALINE; MUSCARINIC M2 RECEPTOR; MUSCARINIC M3 RECEPTOR; MUSCARINIC RECEPTOR BLOCKING AGENT; PROTEIN KINASE C; THRX 18207; THRX 199874; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLADDER; CONTROLLED STUDY; DETRUSOR MUSCLE; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVATION; MALE; NONHUMAN; PROTEIN BINDING; PROTEIN FUNCTION; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE RELAXATION;

ADRENERGIC BETA-AGONISTS; ANIMALS; CARBACHOL; ISOPROTERENOL; MALE; MUSCARINIC AGONISTS; MUSCARINIC ANTAGONISTS; MUSCLE RELAXATION; RATS; RATS, WISTAR; RECEPTOR, MUSCARINIC M2; RECEPTOR, MUSCARINIC M3; RECEPTORS, ADRENERGIC, BETA; SIGNAL TRANSDUCTION; URINARY BLADDER;

EID: 83455210932     PISSN: 00281298     EISSN: 14321912     Source Type: Journal    
DOI: 10.1007/s00210-011-0689-8     Document Type: Article

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