Indole-containing fractions of brassica rapa inhibit inducible nitric oxide synthase and pro-inflammatory cytokine expression by inactivating nuclear factor-κB

Journal of Medicinal Food

Volumn 14, Issue 12, 2011, Pages 1527-1537

  Shin, Ji Sun ^a   Yun, Chang Hyeon ^a   Cho, Young Wuk ^a   Baek, Nam In ^a   Choi, Myung Sook ^b   Jeong, Tae Sook ^c   Chung, Hae Gon ^d   Lee, Kyung Tae ^a  

^a Kyung Hee University   (South Korea)

^b Kyungpook National University   (South Korea)

^c Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^d GangHwa Agricultural R and D Center   (South Korea)

Author keywords

Brassica rapa; cytokine; inflammation; nitric oxide; nuclear factor jB

Indexed keywords

ANTIINFLAMMATORY AGENT; ANTINOCICEPTIVE AGENT; ARVELEXIN; CAULILEXIN C; CYCLOOXYGENASE 2; I KAPPA B; IBUPROFEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDOLE DERIVATIVE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; PLANT EXTRACT; PROSTAGLANDIN E2; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTINOCICEPTION; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; DNA BINDING; DRUG ISOLATION; GENE TRANSLOCATION; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; IN VIVO STUDY; MACROPHAGE; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PAW EDEMA; PLANT ROOT; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; RAT; TURNIP; WRITING;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BRASSICA RAPA; CELL LINE; CYCLOOXYGENASE 2; DINOPROSTONE; GENE EXPRESSION REGULATION; HUMANS; INDOLES; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MALE; MICE; MICE, INBRED ICR; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; PHOSPHORYLATION; PLANT EXTRACTS; PLANT ROOTS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 83455194602     PISSN: 1096620X     EISSN: 15577600     Source Type: Journal    
DOI: 10.1089/jmf.2011.1611     Document Type: Article

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