-
1
-
-
0036534129
-
Alternative splicing: multiple control mechanisms and involvement in human disease
-
Caceres JF, Kornblihtt AR, (2002) Alternative splicing: multiple control mechanisms and involvement in human disease. Trends Genet 18: 186-193.
-
(2002)
Trends Genet
, vol.18
, pp. 186-193
-
-
Caceres, J.F.1
Kornblihtt, A.R.2
-
2
-
-
56749098074
-
Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing
-
Pan Q, Shai O, Lee LJ, Frey BJ, Blencowe BJ, (2008) Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing. Nat Genet 40: 1413-1415.
-
(2008)
Nat Genet
, vol.40
, pp. 1413-1415
-
-
Pan, Q.1
Shai, O.2
Lee, L.J.3
Frey, B.J.4
Blencowe, B.J.5
-
3
-
-
0037443035
-
Pre-mRNA splicing and human disease
-
Faustino NA, Cooper TA, (2003) Pre-mRNA splicing and human disease. Genes Dev 17: 419-437.
-
(2003)
Genes Dev
, vol.17
, pp. 419-437
-
-
Faustino, N.A.1
Cooper, T.A.2
-
4
-
-
73949128867
-
The pathobiology of splicing
-
Ward AJ, Cooper TA, (2010) The pathobiology of splicing. J Pathol 220: 152-163.
-
(2010)
J Pathol
, vol.220
, pp. 152-163
-
-
Ward, A.J.1
Cooper, T.A.2
-
5
-
-
33746927884
-
The connection between splicing and cancer
-
Srebrow A, Kornblihtt AR, (2006) The connection between splicing and cancer. J Cell Sci 119: 2635-2641.
-
(2006)
J Cell Sci
, vol.119
, pp. 2635-2641
-
-
Srebrow, A.1
Kornblihtt, A.R.2
-
7
-
-
0142134358
-
The relevance of alternative RNA splicing to pharmacogenomics
-
Bracco L, Kearsey J, (2003) The relevance of alternative RNA splicing to pharmacogenomics. Trends Biotechnol 21: 346-353.
-
(2003)
Trends Biotechnol
, vol.21
, pp. 346-353
-
-
Bracco, L.1
Kearsey, J.2
-
8
-
-
29144463738
-
Alternative splicing: a new drug target of the post-genome era
-
Hagiwara M, (2005) Alternative splicing: a new drug target of the post-genome era. Biochim Biophys Acta 1754: 324-331.
-
(2005)
Biochim Biophys Acta
, vol.1754
, pp. 324-331
-
-
Hagiwara, M.1
-
9
-
-
45249091505
-
Substances that can change alternative splice-site selection
-
Sumanasekera C, Watt DS, Stamm S, (2008) Substances that can change alternative splice-site selection. Biochem Soc Trans 36: 483-490.
-
(2008)
Biochem Soc Trans
, vol.36
, pp. 483-490
-
-
Sumanasekera, C.1
Watt, D.S.2
Stamm, S.3
-
10
-
-
37849029826
-
Caffeine regulates alternative splicing in a subset of cancer-associated genes: a role for SC35
-
Shi J, Hu Z, Pabon K, Scotto KW, (2008) Caffeine regulates alternative splicing in a subset of cancer-associated genes: a role for SC35. Mol Cell Biol 28: 883-895.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 883-895
-
-
Shi, J.1
Hu, Z.2
Pabon, K.3
Scotto, K.W.4
-
11
-
-
0036527775
-
Histone-deacetylase inhibitors: novel drugs for the treatment of cancer
-
Johnstone RW, (2002) Histone-deacetylase inhibitors: novel drugs for the treatment of cancer. Nat Rev Drug Discov 1: 287-299.
-
(2002)
Nat Rev Drug Discov
, vol.1
, pp. 287-299
-
-
Johnstone, R.W.1
-
12
-
-
33745962138
-
Therapeutic potential of resveratrol: the in vivo evidence
-
Baur JA, Sinclair DA, (2006) Therapeutic potential of resveratrol: the in vivo evidence. Nat Rev Drug Discov 5: 493-506.
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 493-506
-
-
Baur, J.A.1
Sinclair, D.A.2
-
13
-
-
43549088782
-
Resveratrol: a multitargeted agent for age-associated chronic diseases
-
Harikumar KB, Aggarwal BB, (2008) Resveratrol: a multitargeted agent for age-associated chronic diseases. Cell Cycle 7: 1020-1035.
-
(2008)
Cell Cycle
, vol.7
, pp. 1020-1035
-
-
Harikumar, K.B.1
Aggarwal, B.B.2
-
14
-
-
33747886389
-
Resveratrol-a boon for treating Alzheimer's disease?
-
Anekonda TS, (2006) Resveratrol-a boon for treating Alzheimer's disease? Brain Res Rev 52: 316-326.
-
(2006)
Brain Res Rev
, vol.52
, pp. 316-326
-
-
Anekonda, T.S.1
-
15
-
-
33751072349
-
Resveratrol improves health and survival of mice on a high-calorie diet
-
Baur JA, Pearson KJ, Price NL, Jamieson HA, Lerin C, et al. (2006) Resveratrol improves health and survival of mice on a high-calorie diet. Nature 444: 337-342.
-
(2006)
Nature
, vol.444
, pp. 337-342
-
-
Baur, J.A.1
Pearson, K.J.2
Price, N.L.3
Jamieson, H.A.4
Lerin, C.5
-
16
-
-
3943071801
-
Sirtuin activators mimic caloric restriction and delay ageing in metazoans
-
Wood JG, Rogina B, Lavu S, Howitz K, Helfand SL, et al. (2004) Sirtuin activators mimic caloric restriction and delay ageing in metazoans. Nature 430: 686-689.
-
(2004)
Nature
, vol.430
, pp. 686-689
-
-
Wood, J.G.1
Rogina, B.2
Lavu, S.3
Howitz, K.4
Helfand, S.L.5
-
17
-
-
13944253348
-
Calorie restriction-the SIR2 connection
-
Guarente L, Picard F, (2005) Calorie restriction-the SIR2 connection. Cell 120: 473-482.
-
(2005)
Cell
, vol.120
, pp. 473-482
-
-
Guarente, L.1
Picard, F.2
-
18
-
-
70350524083
-
Resveratrol is Not a Direct Activator of SIRT1 Enzyme Activity
-
Beher D, Wu J, Cumine S, Kim KW, Lu SC, et al. (2009) Resveratrol is Not a Direct Activator of SIRT1 Enzyme Activity. Chem Biol Drug Des 74: 619-624.
-
(2009)
Chem Biol Drug Des
, vol.74
, pp. 619-624
-
-
Beher, D.1
Wu, J.2
Cumine, S.3
Kim, K.W.4
Lu, S.C.5
-
19
-
-
77950246109
-
SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1
-
Pacholec M, Chrunyk BA, Cunningham D, Flynn D, Griffith DA, et al. (2010) SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1. J Biol Chem 285: 8340-8351.
-
(2010)
J Biol Chem
, vol.285
, pp. 8340-8351
-
-
Pacholec, M.1
Chrunyk, B.A.2
Cunningham, D.3
Flynn, D.4
Griffith, D.A.5
-
20
-
-
21644470770
-
A forkhead in the road to longevity: the molecular basis of lifespan becomes clearer. [Invited Review]
-
Morris BJ, (2005) A forkhead in the road to longevity: the molecular basis of lifespan becomes clearer. [Invited Review]. J Hypertens 23: 1285-1309.
-
(2005)
J Hypertens
, vol.23
, pp. 1285-1309
-
-
Morris, B.J.1
-
21
-
-
77949887506
-
Mammalian sirtuins: biological insights and disease relevance
-
Haigis MC, Sinclair DA, (2010) Mammalian sirtuins: biological insights and disease relevance. Annu Rev Pathol 5: 253-295.
-
(2010)
Annu Rev Pathol
, vol.5
, pp. 253-295
-
-
Haigis, M.C.1
Sinclair, D.A.2
-
22
-
-
1242342067
-
Resveratrol modulates the phosphoinositide 3-kinase pathway through an estrogen receptor alpha-dependent mechanism: relevance in cell proliferation
-
Pozo-Guisado E, Lorenzo-Benayas MJ, Fernandez-Salguero PM, (2004) Resveratrol modulates the phosphoinositide 3-kinase pathway through an estrogen receptor alpha-dependent mechanism: relevance in cell proliferation. Int J Cancer 109: 167-173.
-
(2004)
Int J Cancer
, vol.109
, pp. 167-173
-
-
Pozo-Guisado, E.1
Lorenzo-Benayas, M.J.2
Fernandez-Salguero, P.M.3
-
23
-
-
64549127790
-
PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure
-
Canto C, Auwerx J, (2009) PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure. Curr Opin Lipidol 20: 98-105.
-
(2009)
Curr Opin Lipidol
, vol.20
, pp. 98-105
-
-
Canto, C.1
Auwerx, J.2
-
24
-
-
63549108476
-
Different Dietary Restriction Regimens Extend Lifespan by both Independent and Overlapping Genetic Pathways in C. elegans
-
Greer EL, Brunet A, (2009) Different Dietary Restriction Regimens Extend Lifespan by both Independent and Overlapping Genetic Pathways in C. elegans. Aging Cell 8: 113-127.
-
(2009)
Aging Cell
, vol.8
, pp. 113-127
-
-
Greer, E.L.1
Brunet, A.2
-
25
-
-
20444485396
-
Interaction of resveratrol and genistein with nucleic acids
-
Usha S, Johnson IM, Malathi R, (2005) Interaction of resveratrol and genistein with nucleic acids. J Biochem Mol Biol 38: 198-205.
-
(2005)
J Biochem Mol Biol
, vol.38
, pp. 198-205
-
-
Usha, S.1
Johnson, I.M.2
Malathi, R.3
-
26
-
-
0347623371
-
Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays
-
Johnson JM, Castle J, Garrett-Engele P, Kan Z, Loerch PM, et al. (2003) Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays. Science 302: 2141-2144.
-
(2003)
Science
, vol.302
, pp. 2141-2144
-
-
Johnson, J.M.1
Castle, J.2
Garrett-Engele, P.3
Kan, Z.4
Loerch, P.M.5
-
27
-
-
37749054939
-
Induction of full-length survival motor neuron by polyphenol botanical compounds
-
Sakla MS, Lorson CL, (2008) Induction of full-length survival motor neuron by polyphenol botanical compounds. Hum Genet 122: 635-643.
-
(2008)
Hum Genet
, vol.122
, pp. 635-643
-
-
Sakla, M.S.1
Lorson, C.L.2
-
28
-
-
0033485795
-
The in vivo minigene approach to analyze tissue-specific splicing
-
Stoss O, Stoilov P, Hartmann AM, Nayler O, Stamm S, (1999) The in vivo minigene approach to analyze tissue-specific splicing. Brain Res Brain Res Protoc 4: 383-394.
-
(1999)
Brain Res Brain Res Protoc
, vol.4
, pp. 383-394
-
-
Stoss, O.1
Stoilov, P.2
Hartmann, A.M.3
Nayler, O.4
Stamm, S.5
-
30
-
-
33847630730
-
The gene encoding the splicing factor SF2/ASF is a proto-oncogene
-
Karni R, de Stanchina E, Lowe SW, Sinha R, Mu D, et al. (2007) The gene encoding the splicing factor SF2/ASF is a proto-oncogene. Nat Struct Mol Biol 14: 185-193.
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 185-193
-
-
Karni, R.1
de Stanchina, E.2
Lowe, S.W.3
Sinha, R.4
Mu, D.5
-
31
-
-
0242626913
-
Heterogeneous nuclear ribonucleoprotein particle A/B proteins and the control of alternative splicing of the mammalian heterogeneous nuclear ribonucleoprotein particle A1 pre-mRNA
-
Chabot B, LeBel C, Hutchison S, Nasim FH, Simard MJ, (2003) Heterogeneous nuclear ribonucleoprotein particle A/B proteins and the control of alternative splicing of the mammalian heterogeneous nuclear ribonucleoprotein particle A1 pre-mRNA. Prog Mol Subcell Biol 31: 59-88.
-
(2003)
Prog Mol Subcell Biol
, vol.31
, pp. 59-88
-
-
Chabot, B.1
LeBel, C.2
Hutchison, S.3
Nasim, F.H.4
Simard, M.J.5
-
32
-
-
53849124668
-
Diverse molecular functions of Hu proteins
-
Hinman MN, Lou H, (2008) Diverse molecular functions of Hu proteins. Cell Mol Life Sci 65: 3168-3181.
-
(2008)
Cell Mol Life Sci
, vol.65
, pp. 3168-3181
-
-
Hinman, M.N.1
Lou, H.2
-
33
-
-
33748603768
-
WT1 interacts with the splicing protein RBM4 and regulates its ability to modulate alternative splicing in vivo
-
Markus MA, Heinrich B, Raitskin O, Adams DJ, Mangs H, et al. (2006) WT1 interacts with the splicing protein RBM4 and regulates its ability to modulate alternative splicing in vivo. Exp Cell Res 312: 3379-3388.
-
(2006)
Exp Cell Res
, vol.312
, pp. 3379-3388
-
-
Markus, M.A.1
Heinrich, B.2
Raitskin, O.3
Adams, D.J.4
Mangs, H.5
-
34
-
-
49349112872
-
Polypyrimidine-tract-binding protein: a multifunctional RNA-binding protein
-
Sawicka K, Bushell M, Spriggs KA, Willis AE, (2008) Polypyrimidine-tract-binding protein: a multifunctional RNA-binding protein. Biochem Soc Trans 36: 641-647.
-
(2008)
Biochem Soc Trans
, vol.36
, pp. 641-647
-
-
Sawicka, K.1
Bushell, M.2
Spriggs, K.A.3
Willis, A.E.4
-
35
-
-
0034743627
-
The role of U2AF35 and U2AF65 in enhancer-dependent splicing
-
Graveley BR, Hertel KJ, Maniatis T, (2001) The role of U2AF35 and U2AF65 in enhancer-dependent splicing. RNA 7: 806-818.
-
(2001)
RNA
, vol.7
, pp. 806-818
-
-
Graveley, B.R.1
Hertel, K.J.2
Maniatis, T.3
-
36
-
-
58349102337
-
Dietary activators of Sirt1
-
Allard JS, Perez E, Zou S, de Cabo R, (2009) Dietary activators of Sirt1. Mol Cell Endocrinol 299: 58-63.
-
(2009)
Mol Cell Endocrinol
, vol.299
, pp. 58-63
-
-
Allard, J.S.1
Perez, E.2
Zou, S.3
de Cabo, R.4
-
37
-
-
47849132642
-
Resveratrol in prevention and treatment of common clinical conditions of aging
-
Markus MA, Morris BJ, (2008) Resveratrol in prevention and treatment of common clinical conditions of aging. Clin Interv Aging 3: 331-339.
-
(2008)
Clin Interv Aging
, vol.3
, pp. 331-339
-
-
Markus, M.A.1
Morris, B.J.2
-
38
-
-
29244490598
-
Determinants of exon 7 splicing in the spinal muscular atrophy genes, SMN1 and SMN2
-
Cartegni L, Hastings ML, Calarco JA, de Stanchina E, Krainer AR, (2006) Determinants of exon 7 splicing in the spinal muscular atrophy genes, SMN1 and SMN2. Am J Hum Genet 78: 63-77.
-
(2006)
Am J Hum Genet
, vol.78
, pp. 63-77
-
-
Cartegni, L.1
Hastings, M.L.2
Calarco, J.A.3
de Stanchina, E.4
Krainer, A.R.5
-
39
-
-
0034670097
-
Regulation of SRp20 exon 4 splicing
-
Jumaa H, Nielsen PJ, (2000) Regulation of SRp20 exon 4 splicing. Biochim Biophys Acta 1494: 137-143.
-
(2000)
Biochim Biophys Acta
, vol.1494
, pp. 137-143
-
-
Jumaa, H.1
Nielsen, P.J.2
-
40
-
-
0034602848
-
Modulation of RNA function by aminoglycoside antibiotics
-
Schroeder R, Waldsich C, Wank H, (2000) Modulation of RNA function by aminoglycoside antibiotics. EMBO J 19: 1-9.
-
(2000)
EMBO J
, vol.19
, pp. 1-9
-
-
Schroeder, R.1
Waldsich, C.2
Wank, H.3
-
41
-
-
58249093940
-
The SR protein family of splicing factors: master regulators of gene expression
-
Long JC, Caceres JF, (2009) The SR protein family of splicing factors: master regulators of gene expression. Biochem J 417: 15-27.
-
(2009)
Biochem J
, vol.417
, pp. 15-27
-
-
Long, J.C.1
Caceres, J.F.2
-
42
-
-
74449089662
-
The anti-inflammatory activity of the polyphenol resveratrol may be partially related to inhibition of tumour necrosis factor-alpha (TNF-alpha) pre-mRNA splicing
-
Leiro JM, Varela M, Piazzon MC, Arranz JA, Noya M, et al. (2010) The anti-inflammatory activity of the polyphenol resveratrol may be partially related to inhibition of tumour necrosis factor-alpha (TNF-alpha) pre-mRNA splicing. Mol Immunol 47: 1114-1120.
-
(2010)
Mol Immunol
, vol.47
, pp. 1114-1120
-
-
Leiro, J.M.1
Varela, M.2
Piazzon, M.C.3
Arranz, J.A.4
Noya, M.5
-
43
-
-
77949357437
-
Cardioprotection by resveratrol: a novel mechanism via autophagy involving the mTORC2 pathway
-
Gurusamy N, Lekli I, Mukherjee S, Ray D, Ahsan MK, et al. (2010) Cardioprotection by resveratrol: a novel mechanism via autophagy involving the mTORC2 pathway. Cardiovasc Res 86: 103-112.
-
(2010)
Cardiovasc Res
, vol.86
, pp. 103-112
-
-
Gurusamy, N.1
Lekli, I.2
Mukherjee, S.3
Ray, D.4
Ahsan, M.K.5
-
44
-
-
27744569843
-
mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events
-
Holz MK, Ballif BA, Gygi SP, Blenis J, (2005) mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events. Cell 123: 569-580.
-
(2005)
Cell
, vol.123
, pp. 569-580
-
-
Holz, M.K.1
Ballif, B.A.2
Gygi, S.P.3
Blenis, J.4
-
45
-
-
41849086320
-
FOXO-binding partners: it takes two to tango
-
van der Vos KE, Coffer PJ, (2008) FOXO-binding partners: it takes two to tango. Oncogene 27: 2289-2299.
-
(2008)
Oncogene
, vol.27
, pp. 2289-2299
-
-
van der Vos, K.E.1
Coffer, P.J.2
|