The anti-inflammatory activity of the polyphenol resveratrol may be partially related to inhibition of tumour necrosis factor-α (TNF-α) pre-mRNA splicing

Molecular Immunology

Volumn 47, Issue 5, 2010, Pages 1114-1120

  Leiro, José M ^a   Varela, Monica ^a   Piazzon, M Carla ^a   Arranz, Juan A ^a   Noya, Manuel ^a   Lamas, Jesus ^a  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

IL 1 ; Inflammation; Resveratrol; Splicing; TNF ; Turbot

Indexed keywords

INTERLEUKIN 1BETA; MESSENGER RNA PRECURSOR; POLYSACCHARIDE; RESVERATROL; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; DRUG MECHANISM; FISH; GENE EXPRESSION; GENETIC TRANSCRIPTION; HOUSEKEEPING GENE; INFLAMMATION; LEUKOCYTE; MESSENGER RNA SYNTHESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PERITONEAL CAVITY; PRIORITY JOURNAL; RNA SPLICING; SEAWEED;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; FISH PROTEINS; FLATFISHES; FLAVONOIDS; INTERLEUKIN-1BETA; KIDNEY; LEUKOCYTES; PHENOLS; POLYSACCHARIDES; RNA PRECURSORS; RNA SPLICING; STILBENES; TUMOR NECROSIS FACTOR-ALPHA; ULVA;

SCOPHTHALMIDAE; SCOPHTHALMUS MAXIMUS; ULVA RIGIDA; VERTEBRATA;

EID: 74449089662     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2009.10.030     Document Type: Article

References (42)

1. Bi X.L., Yang J.Y., Dong Y.X., Wang J.M., Cui Y.H., Ikeshima T., Zhao Y.Q., and Wu C.F. Resveratrol inhibits nitric oxide and TNF-α production by lipopolysaccharide-activated microglia. Int. Immunopharmacol. 5 (2005) 185-193
2. Bird S., Zou J., Wang T., Munday B., Cunningham C., and Secombes C.J. Evolution of interleukin-1beta. Cytokine Growth Factor Rev. 13 (2002) 483-502
3. Bradley J.R. TNF-mediated inflammatory disease. J. Pathol. 214 (2008) 149-160
4. Buck I., Morceau F., Grigorakaki C., Dicato M., and Diederich M. Linking anemia to inflammation and cancer: the crucial role of TNFα. Biochem. Pharmacol. 77 (2009) 1572-1579
5. Bureau G., Longpré F., and Martinoli M.G. Resveratrol and quercetin, two natural polyphenols, reduce apoptotic neuronal cell death induced by neuroinflammation. J. Neurosci. Res. 86 (2008) 403-410
6. Castro R., Lamas J., Morais P., Sanmartín M.L., Orallo F., and Leiro J. Resveratrol modulates innate and inflammatory responses in fish leucocytes. Vet. Immunol. Immunopathol. 126 (2008) 9-19
7. Castro R., Piazzon M.C., Zarra I., Leiro J., Noya M., and Lamas J. Stimulation of turbot phagocytes by Ulva rigida C. Agardh polysaccharides. Aquaculture 254 (2006) 9-20
8. Castro R., Zarra I., and Lamas J. Water-soluble seaweed extracts modulate the respiratory burst activity of turbot phagocytes. Aquaculture 229 (2004) 67-78
9. Chadzinska M., Scislowska-Czarnecka A., and Plytycz B. Inhibitory effects of morphine on some inflammation-related parameters in the goldfish Carassius auratus L. Fish Shellfish Immunol. 10 (2000) 531-542
10. Covello J.M., Bird S., Morrison R.N., Battaglene S.C., Secombes C.J., and Nowak B.F. Cloning and expression analysis of three striped trumpeter (Latris lineata) pro-inflammatory cytokines, TNF-alpha, IL-1beta and IL-8, in response to infection by the ectoparasitic, Chondracanthus goldsmidi. Fish Shellfish Immunol. 26 (2009) 773-786
11. de la Lastra C.A., and Villegas I. Resveratrol as an anti-inflammatory and anti-aging agent: mechanisms and clinical implications. Mol. Nutr. Food Res. 49 (2005) 405-430
12. Feng Y.H., Zhu Y.N., Liu J., Ren Y.X., Xu J.Y., Yang Y.F., Li X.Y., and Zou J.P. Differential regulation of resveratrol on lipopolysacchride-stimulated human macrophages with or without IFN-gamma pre-priming. Int. Immunopharmacol. 4 (2004) 713-720
13. García-Castillo J., Chaves-Pozo E., Olivares P., Pelegrín P., Meseguer J., and Mulero V. The tumor necrosis factor alpha of the bony fish seabream exhibits the in vivo proinflammatory and proliferative activities of its mammalian counterparts, yet it functions in a species-specific manner. Cell. Mol. Life Sci. 61 (2004) 1331-1340
14. García-Castillo J., Pelegrín P., Mulero V., and Meseguer J. Molecular cloning and expression analysis of tumor necrosis factor alpha from a marine fish reveal its constitutive expression and ubiquitous nature. Immunogenetics 54 (2002) 200-207
15. Goetz F.W., Planas J.V., and MacKenzie S. Tumor necrosis factors. Dev. Comp. Immunol. 28 (2004) 487-497
16. Grayfer L., Walsh J.G., and Belosevic M. Characterization and functional analysis of goldfish (Carassius auratus L.) tumor necrosis factor-alpha. Dev. Comp. Immunol. 32 (2008) 532-543
17. Hirono I., Nam B.H., Kurobe T., and Aoki T. Molecular cloning, characterization, and expression of TNF cDNA and gene from Japanese flounder Paralychthys olivaceus. J. Immunol. 165 (2000) 4423-4427
18. Jarrous N., and Kaempfer R. Induction of human interleukin-1 gene expression by retinoic acid and its regulation at processing of precursor transcripts. J. Biol. Chem. 269 (1994) 23141-23149
19. Jarrous N., Osman F., and Kaempfer R. 2-Aminopurine selectively inhibits splicing of tumor necrosis factor alpha mRNA. Mol. Cell. Biol. 16 (1996) 2814-2822
20. Kang O.H., Jang H.J., Chae H.S., Oh Y.C., Choi J.G., Lee Y.S., Kim J.H., Kim Y.C., Sohn D.H., Park H., and Kwon D.Y. Anti-inflammatory mechanisms of resveratrol in activated HMC-1 cells: pivotal roles of NF-kappaB and MAPK. Pharmacol. Res. 59 (2009) 330-337
21. Kowalski J., Samojedny A., Paul M., Pietsz G., and Wilczok T. Effect of apigenin, kaempferol and resveratrol on the expression of interleukin-1beta and tumor necrosis factor-alpha genes in J774.2 macrophages. Pharmacol. Rep. 57 (2005) 390-394
22. Laing K.J., Wang T., Zou J., Holland J., Hong S., Bols N., Hirono I., Aoki T., and Secombes C.J. Cloning and expression analysis of rainbow trout Oncorhynchus mykiss tumour necrosis factor alpha. Eur. J. Biochem. 268 (2001) 1315-1322
23. Leiro J., Iglesias R., Paramá A., Aragort W., and Sanmartín M.L. PCR detection of Tetramicra brevifilum (Microspora) infection in turbot (Scophthalmus maximus L.) musculature. Parasitology 124 (2002) 145-151
24. Leiro J.M., Castro R., Arranz J.A., and Lamas J. Immunomodulating activities of acidic sulphated polysaccharides obtained from the seaweed Ulva rigida C. Agardh. Int. Immunopharmacol. 7 (2007) 879-888
25. Locksley R.M., Killeen N., and Lenardo M.J. The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell 104 (2001) 487-501
26. Ma Z.H., Ma Q.Y., Wang L.C., Sha H.C., Wu S.L., and Zhang M. Effect of resveratrol on peritoneal macrophages in rats with severe acute pancreatitis. Inflamm. Res. 54 (2005) 522-527
27. Meng X.L., Yang J.Y., Chen G.L., Zhang L.J., Wang L.H., Li J., Wang J.M., and Wu C.F. RV09, a novel resveratrol analogue, inhibits NO and TNF-alpha production by LPS-activated microglia. Int. Immunopharmacol. 8 (2008) 1074-1082
28. Möller B., and Villiger P.M. Inhibition of IL-1, IL-6, and TNF-alpha in immune-mediated inflammatory diseases. Springer Semin. Immunopathol. 27 (2006) 391-408
29. Morrison R.N., Zou J., Secombes C.J., Scapigliati G., Adams M.B., and Nowak B.F. Molecular cloning and expression analysis of tumour necrosis factor-α in amoebic gill disease (AGD)-affected Atlantic salmon (Salmo salar L.). Fish Shellfish Immunol. 23 (2007) 1015-1031
30. Nascimento D.S., Pereira P.J., Reis M.I., do Vale A., Zou J., Silva M.T., Secombes C.J., and dos Santos N.M. Molecular cloning and expression analysis of sea bass (Dicentrarchus labrax L.) tumor necrosis factor-alpha (TNF-alpha). Fish Shellfish Immunol. 23 (2007) 701-710
31. Ordás M.C., Costa M.M., Roca F.J., López-Castejón G., Mulero V., Meseguer J., Figueras A., and Novoa B. Turbot TNFα gene: molecular characterization and biological activity of the recombinant protein. Mol. Immunol. 44 (2007) 389-400
32. Osman F., Jarrous N., Ben-Asouli Y., and Kaempfer R. A cis-acting element in the 3′-untranslated region of human TNF-alpha mRNA renders splicing dependent on the activation of protein kinase PKR. Genes Dev. 13 (1999) 3280-3293
33. Richard N., Porath D., Radspieler A., and Schwager J. Effects of resveratrol, piceatannol, tri-acetoxystilbene, and genistein on the inflammatory response of human peripheral blood leukocytes. Mol. Nutr. Food Res. 49 (2005) 431-442
34. Saeij J.P., Stet R.J., de Vries B.J., van Muiswinkel W.B., and Wiegertjes G.F. Molecular and functional characterization of carp TNF: a link between TNF polymorphism and trypanotolerance?. Dev. Comp. Immunol. 27 (2003) 29-41
35. Savan R., Kono T., Igawa D., and Sakai M. A novel tumor necrosis factor (TNF) gene present in tandem with the TNF-α gene on the same chromosome in teleosts. Immunogenetics 57 (2005) 140-150
36. Sumanasekera C., Watt D.S., and Stamm S. Substances that can change alternative splice-site selection. Biochem. Soc. Trans. 36 (2008) 483-490
37. Szlosarek P., Charles K.A., and Balkwill F.R. Tumour necrosis factor-alpha as a tumour promoter. Eur. J. Cancer 42 (2006) 745-750
38. Tao H.Y., Wu C.F., Zhou Y., Gong W.H., Zhang X., Iribarren P., Zhao Y.Q., Le Y.Y., and Wang J.M. The grape component resveratrol interferes with the function of chemoattractant receptors on phagocytic leukocytes. Cell. Mol. Immunol. 1 (2004) 50-56
39. Tincani A., Andreoli L., Bazzani C., Bosiso D., and Sozzani S. Inflammatory molecules: a target for treatment of systemic autoimmune diseases. Autoimmun. Rev. 7 (2007) 1-7
40. Uenobe M., Kohchi C., Yoshioka N., Yuasa A., Inagawa H., Morii K., Nishizawa T., Takahashi Y., and Soma G. Cloning and characterization of a TNF-like protein of Plecoglossus altivelis (ayu fish). Mol. Immunol. 44 (2007) 1115-1122
41. Zhu J., Yong W., Wu X., Yu Y., Lv J., Liu C., Mao X., Zhu Y., Xu K., Han X., and Liu C. Anti-inflammatory effect of resveratrol on TNF-alpha-induced MCP-1 expression in adipocytes. Biochem. Biophys. Res. Commun. 369 (2008) 471-477
42. Zou J., Secombes C.J., Long S., Miller N., Clem L.W., and Chinchar V.G. Molecular identification and expression analysis of tumor necrosis factor in channel catfish (Ictalurus punctatus). Dev. Comp. Immunol. 27 (2003) 845-858