Premutation huntingtin allele adopts a non-B conformation and contains a hot spot for DNA damage

Biochemical and Biophysical Research Communications

Volumn 416, Issue 1-2, 2011, Pages 146-152

  Jarem, Daniel A ^a   Delaney, Sarah ^a  

^a BROWN UNIVERSITY   (United States)

Author keywords

Chemical probes; Differential scanning calorimetry; Huntington's disease; Non B DNA conformation; Oxidative damage; Trinucleotide repeat expansion

Indexed keywords

HUNTINGTIN; NUCLEIC ACID BASE; PEROXYNITRITE;

ALLELE; ARTICLE; CALORIMETRY; CORRELATION ANALYSIS; DNA CONFORMATION; DNA DAMAGE; HUNTINGTON CHOREA; PRIORITY JOURNAL; SEQUENCE ANALYSIS; STRUCTURE ANALYSIS; THERMODYNAMICS; TRINUCLEOTIDE REPEAT;

ALLELES; CALORIMETRY; DNA DAMAGE; DNA, B-FORM; HUMANS; HUNTINGTON DISEASE; MUTATION; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; NUCLEIC ACID CONFORMATION; PEROXYNITROUS ACID; TRANSITION TEMPERATURE; TRINUCLEOTIDE REPEATS;

EID: 83055185701     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.11.013     Document Type: Article

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