-
1
-
-
0030810722
-
Cloning of two human homologs of the Drosophila single-minded gene SIM1 on chromosome 6q and SIM2 on 21q within the Down syndrome chromosomal region
-
Chrast R, Scott HS, Chen H, Kudoh J, Rossier C, et al. (1997) Cloning of two human homologs of the Drosophila single-minded gene SIM1 on chromosome 6q and SIM2 on 21q within the Down syndrome chromosomal region. Genome Res 7: 615-624.
-
(1997)
Genome Res
, vol.7
, pp. 615-624
-
-
Chrast, R.1
Scott, H.S.2
Chen, H.3
Kudoh, J.4
Rossier, C.5
-
2
-
-
0030740207
-
The murine Sim-2 gene product inhibits transcription by active repression and functional interference
-
Moffett P, Reece M, Pelletier J, (1997) The murine Sim-2 gene product inhibits transcription by active repression and functional interference. Mol Cell Biol 17: 4933-4947.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 4933-4947
-
-
Moffett, P.1
Reece, M.2
Pelletier, J.3
-
3
-
-
0032837516
-
Mild impairment of learning and memory in mice overexpressing the mSim2 gene located on chromosome 16: an animal model of Down's syndrome
-
Ema M, Ikegami S, Hosoya T, Mimura J, Ohtani H, et al. (1999) Mild impairment of learning and memory in mice overexpressing the mSim2 gene located on chromosome 16: an animal model of Down's syndrome. Hum Mol Genet 8: 1409-1415.
-
(1999)
Hum Mol Genet
, vol.8
, pp. 1409-1415
-
-
Ema, M.1
Ikegami, S.2
Hosoya, T.3
Mimura, J.4
Ohtani, H.5
-
4
-
-
0033977276
-
Different transcriptional properties of mSim-1 and mSim-2
-
Moffett P, Pelletier J, (2000) Different transcriptional properties of mSim-1 and mSim-2. FEBS Lett 466: 80-86.
-
(2000)
FEBS Lett
, vol.466
, pp. 80-86
-
-
Moffett, P.1
Pelletier, J.2
-
5
-
-
0035972868
-
Molecular mechanisms of human single-minded 2 (SIM2) gene expression: identification of a promoter site in the SIM2 genomic sequence
-
Yamaki A, Tochigi J, Kudoh J, Minoshima S, Shimizu N, et al. (2001) Molecular mechanisms of human single-minded 2 (SIM2) gene expression: identification of a promoter site in the SIM2 genomic sequence. Gene 270: 265-275.
-
(2001)
Gene
, vol.270
, pp. 265-275
-
-
Yamaki, A.1
Tochigi, J.2
Kudoh, J.3
Minoshima, S.4
Shimizu, N.5
-
6
-
-
0036870701
-
Down's syndrome-associated single minded gene as a novel tumor marker
-
Deyoung MP, Scheurle D, Damania H, Zylberberg C, Narayanan R, (2002) Down's syndrome-associated single minded gene as a novel tumor marker. Anticancer Res 22: 3149-3157.
-
(2002)
Anticancer Res
, vol.22
, pp. 3149-3157
-
-
Deyoung, M.P.1
Scheurle, D.2
Damania, H.3
Zylberberg, C.4
Narayanan, R.5
-
7
-
-
0037447077
-
Identification of Down's syndrome critical locus gene SIM2-s as a drug therapy target for solid tumors
-
DeYoung MP, Tress M, Narayanan R, (2003) Identification of Down's syndrome critical locus gene SIM2-s as a drug therapy target for solid tumors. Proc Natl Acad Sci U S A 100: 4760-4765.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 4760-4765
-
-
DeYoung, M.P.1
Tress, M.2
Narayanan, R.3
-
8
-
-
0141863174
-
Down's syndrome-associated Single Minded 2 gene as a pancreatic cancer drug therapy target
-
DeYoung MP, Tress M, Narayanan R, (2003) Down's syndrome-associated Single Minded 2 gene as a pancreatic cancer drug therapy target. Cancer Lett 200: 25-31.
-
(2003)
Cancer Lett
, vol.200
, pp. 25-31
-
-
DeYoung, M.P.1
Tress, M.2
Narayanan, R.3
-
9
-
-
24644525067
-
Inhibition of Single Minded 2 gene expression mediates tumor-selective apoptosis and differentiation in human colon cancer cells
-
Aleman MJ, DeYoung MP, Tress M, Keating P, Perry GW, et al. (2005) Inhibition of Single Minded 2 gene expression mediates tumor-selective apoptosis and differentiation in human colon cancer cells. Proc Natl Acad Sci U S A 102: 12765-12770.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 12765-12770
-
-
Aleman, M.J.1
DeYoung, M.P.2
Tress, M.3
Keating, P.4
Perry, G.W.5
-
10
-
-
33847313222
-
Inhibition of breast cancer growth and invasion by single-minded 2s
-
Kwak HI, Gustafson T, Metz RP, Laffin B, Schedin P, et al. (2007) Inhibition of breast cancer growth and invasion by single-minded 2s. Carcinogenesis 28: 259-266.
-
(2007)
Carcinogenesis
, vol.28
, pp. 259-266
-
-
Kwak, H.I.1
Gustafson, T.2
Metz, R.P.3
Laffin, B.4
Schedin, P.5
-
11
-
-
77953708821
-
Single minded 2-s (SIM2-s) gene is expressed in human GBM cells and involved in GBM invasion
-
He Q, Li G, Su Y, Shen J, Liu Q, Single minded 2-s (SIM2-s) gene is expressed in human GBM cells and involved in GBM invasion. Cancer Biol Ther 9: 430-436.
-
Cancer Biol Ther
, vol.9
, pp. 430-436
-
-
He, Q.1
Li, G.2
Su, Y.3
Shen, J.4
Liu, Q.5
-
12
-
-
70349448674
-
Identification of the transcription factor single-minded homologue 2 as a potential biomarker and immunotherapy target in prostate cancer
-
Arredouani MS, Lu B, Bhasin M, Eljanne M, Yue W, et al. (2009) Identification of the transcription factor single-minded homologue 2 as a potential biomarker and immunotherapy target in prostate cancer. Clin Cancer Res 15: 5794-5802.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 5794-5802
-
-
Arredouani, M.S.1
Lu, B.2
Bhasin, M.3
Eljanne, M.4
Yue, W.5
-
13
-
-
33847396441
-
Increased expression of SIM2-s protein is a novel marker of aggressive prostate cancer
-
Halvorsen OJ, Rostad K, Oyan AM, Puntervoll H, Bo TH, et al. (2007) Increased expression of SIM2-s protein is a novel marker of aggressive prostate cancer. Clin Cancer Res 13: 892-897.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 892-897
-
-
Halvorsen, O.J.1
Rostad, K.2
Oyan, A.M.3
Puntervoll, H.4
Bo, T.H.5
-
14
-
-
70350064297
-
The HIF1alpha-inducible pro-cell death gene BNIP3 is a novel target of SIM2s repression through cross-talk on the hypoxia response element
-
Farrall AL, Whitelaw ML, (2009) The HIF1alpha-inducible pro-cell death gene BNIP3 is a novel target of SIM2s repression through cross-talk on the hypoxia response element. Oncogene 28: 3671-3680.
-
(2009)
Oncogene
, vol.28
, pp. 3671-3680
-
-
Farrall, A.L.1
Whitelaw, M.L.2
-
15
-
-
23844524767
-
Gene signatures of progression and metastasis in renal cell cancer
-
Jones J, Otu H, Spentzos D, Kolia S, Inan M, et al. (2005) Gene signatures of progression and metastasis in renal cell cancer. Clin Cancer Res 11: 5730-5739.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 5730-5739
-
-
Jones, J.1
Otu, H.2
Spentzos, D.3
Kolia, S.4
Inan, M.5
-
16
-
-
0035793042
-
Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection
-
Li C, Wong WH, (2001) Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection. Proc Natl Acad Sci U S A 98: 31-36.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 31-36
-
-
Li, C.1
Wong, W.H.2
-
17
-
-
0037095769
-
Accuracy and calibration of commercial oligonucleotide and custom cDNA microarrays
-
Yuen T, Wurmbach E, Pfeffer RL, Ebersole BJ, Sealfon SC, (2002) Accuracy and calibration of commercial oligonucleotide and custom cDNA microarrays. Nucleic Acids Res 30: e48.
-
(2002)
Nucleic Acids Res
, vol.30
-
-
Yuen, T.1
Wurmbach, E.2
Pfeffer, R.L.3
Ebersole, B.J.4
Sealfon, S.C.5
-
18
-
-
0037131389
-
"Stemness": transcriptional profiling of embryonic and adult stem cells
-
Ramalho-Santos M, Yoon S, Matsuzaki Y, Mulligan RC, Melton DA, (2002) "Stemness": transcriptional profiling of embryonic and adult stem cells. Science 298: 597-600.
-
(2002)
Science
, vol.298
, pp. 597-600
-
-
Ramalho-Santos, M.1
Yoon, S.2
Matsuzaki, Y.3
Mulligan, R.C.4
Melton, D.A.5
-
19
-
-
51649111988
-
Gene expression profile of mouse prostate tumors reveals dysregulations in major biological processes and identifies potential murine targets for preclinical development of human prostate cancer therapy
-
Haram KM, Peltier HJ, Lu B, Bhasin M, Otu HH, et al. (2008) Gene expression profile of mouse prostate tumors reveals dysregulations in major biological processes and identifies potential murine targets for preclinical development of human prostate cancer therapy. Prostate 68: 1517-1530.
-
(2008)
Prostate
, vol.68
, pp. 1517-1530
-
-
Haram, K.M.1
Peltier, H.J.2
Lu, B.3
Bhasin, M.4
Otu, H.H.5
-
20
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
-
Livak KJ, Schmittgen TD, (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
21
-
-
67849106535
-
MetaboAnalyst: a web server for metabolomic data analysis and interpretation
-
Xia J, Psychogios N, Young N, Wishart DS, (2009) MetaboAnalyst: a web server for metabolomic data analysis and interpretation. Nucleic Acids Res 37: W652-660.
-
(2009)
Nucleic Acids Res
, vol.37
-
-
Xia, J.1
Psychogios, N.2
Young, N.3
Wishart, D.S.4
-
22
-
-
79958115671
-
Web-based inference of biological patterns, functions and pathways from metabolomic data using MetaboAnalyst
-
Xia J, Wishart DS Web-based inference of biological patterns, functions and pathways from metabolomic data using MetaboAnalyst. Nat Protoc 6: 743-760.
-
Nat Protoc
, vol.6
, pp. 743-760
-
-
Xia, J.1
Wishart, D.S.2
-
23
-
-
33744948882
-
Differential transcriptional regulation by mouse single-minded 2s
-
Metz RP, Kwak HI, Gustafson T, Laffin B, Porter WW, (2006) Differential transcriptional regulation by mouse single-minded 2s. J Biol Chem 281: 10839-10848.
-
(2006)
J Biol Chem
, vol.281
, pp. 10839-10848
-
-
Metz, R.P.1
Kwak, H.I.2
Gustafson, T.3
Laffin, B.4
Porter, W.W.5
-
24
-
-
0033551070
-
New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway
-
Cantley LC, Neel BG, (1999) New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway. Proc Natl Acad Sci U S A 96: 4240-4245.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 4240-4245
-
-
Cantley, L.C.1
Neel, B.G.2
-
25
-
-
51849111556
-
PI3K pathway alterations in cancer: variations on a theme
-
Yuan TL, Cantley LC, (2008) PI3K pathway alterations in cancer: variations on a theme. Oncogene 27: 5497-5510.
-
(2008)
Oncogene
, vol.27
, pp. 5497-5510
-
-
Yuan, T.L.1
Cantley, L.C.2
-
26
-
-
77950363603
-
The bHLH/PAS transcription factor singleminded 2s promotes mammary gland lactogenic differentiation
-
Wellberg E, Metz RP, Parker C, Porter WW The bHLH/PAS transcription factor singleminded 2s promotes mammary gland lactogenic differentiation. Development 137: 945-952.
-
Development
, vol.137
, pp. 945-952
-
-
Wellberg, E.1
Metz, R.P.2
Parker, C.3
Porter, W.W.4
-
27
-
-
71649086180
-
Toll-like receptor signaling in cell proliferation and survival
-
Li X, Jiang S, Tapping RI Toll-like receptor signaling in cell proliferation and survival. Cytokine 49: 1-9.
-
Cytokine
, vol.49
, pp. 1-9
-
-
Li, X.1
Jiang, S.2
Tapping, R.I.3
-
28
-
-
84864281271
-
The prostate specific membrane antigen regulates the expression of IL-6 and CCL5 in prostate tumour cells by activating the MAPK pathways
-
Colombatti M, Grasso S, Porzia A, Fracasso G, Scupoli MT, et al. (2009) The prostate specific membrane antigen regulates the expression of IL-6 and CCL5 in prostate tumour cells by activating the MAPK pathways. PLoS One 4: e4608.
-
(2009)
PLoS One
, vol.4
-
-
Colombatti, M.1
Grasso, S.2
Porzia, A.3
Fracasso, G.4
Scupoli, M.T.5
-
29
-
-
31944433180
-
Expression of CCL5 (RANTES) and CCR5 in prostate cancer
-
Vaday GG, Peehl DM, Kadam PA, Lawrence DM, (2006) Expression of CCL5 (RANTES) and CCR5 in prostate cancer. Prostate 66: 124-134.
-
(2006)
Prostate
, vol.66
, pp. 124-134
-
-
Vaday, G.G.1
Peehl, D.M.2
Kadam, P.A.3
Lawrence, D.M.4
-
30
-
-
36949008162
-
Prostate cancer antigen-1 contributes to cell survival and invasion though discoidin receptor 1 in human prostate cancer
-
Shimada K, Nakamura M, Ishida E, Higuchi T, Yamamoto H, et al. (2008) Prostate cancer antigen-1 contributes to cell survival and invasion though discoidin receptor 1 in human prostate cancer. Cancer Sci 99: 39-45.
-
(2008)
Cancer Sci
, vol.99
, pp. 39-45
-
-
Shimada, K.1
Nakamura, M.2
Ishida, E.3
Higuchi, T.4
Yamamoto, H.5
-
31
-
-
33749189559
-
Identification of expressed genes characterizing long-term survival in malignant glioma patients
-
Yamanaka R, Arao T, Yajima N, Tsuchiya N, Homma J, et al. (2006) Identification of expressed genes characterizing long-term survival in malignant glioma patients. Oncogene 25: 5994-6002.
-
(2006)
Oncogene
, vol.25
, pp. 5994-6002
-
-
Yamanaka, R.1
Arao, T.2
Yajima, N.3
Tsuchiya, N.4
Homma, J.5
-
32
-
-
63449108743
-
Ha-Ras transformation of MCF10A cells leads to repression of Singleminded-2s through NOTCH and C/EBPbeta
-
Gustafson TL, Wellberg E, Laffin B, Schilling L, Metz RP, et al. (2009) Ha-Ras transformation of MCF10A cells leads to repression of Singleminded-2s through NOTCH and C/EBPbeta. Oncogene 28: 1561-1568.
-
(2009)
Oncogene
, vol.28
, pp. 1561-1568
-
-
Gustafson, T.L.1
Wellberg, E.2
Laffin, B.3
Schilling, L.4
Metz, R.P.5
-
33
-
-
40349091380
-
Loss of singleminded-2s in the mouse mammary gland induces an epithelial-mesenchymal transition associated with up-regulation of slug and matrix metalloprotease 2
-
Laffin B, Wellberg E, Kwak HI, Burghardt RC, Metz RP, et al. (2008) Loss of singleminded-2s in the mouse mammary gland induces an epithelial-mesenchymal transition associated with up-regulation of slug and matrix metalloprotease 2. Mol Cell Biol 28: 1936-1946.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 1936-1946
-
-
Laffin, B.1
Wellberg, E.2
Kwak, H.I.3
Burghardt, R.C.4
Metz, R.P.5
|