Automated microinjection of cell-polymer suspensions in 3D ECM scaffolds for high-throughput quantitative cancer invasion screens

Biomaterials

Volumn 33, Issue 1, 2012, Pages 181-188

  Truong, Hoa H ^a   de Sonneville, Jan ^b   Ghotra, Veerander P S ^a   Xiong, Jiangling ^a   Price, Leo ^a   Hogendoorn, Pancras C W ^c   Spaink, Herman H ^d   van de Water, Bob ^a   Danen, Erik H J ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

^b LEIDEN UNIVERSITY   (Netherlands)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^d LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Cancer; High throughput; Microinjection; Personalized medicine; Screen; Spheroid

Indexed keywords

CANCER; HIGH-THROUGHPUT; MICRO-INJECTION; PERSONALIZED MEDICINES; SCREEN; SPHEROID;

AUTOMATION; CELL CULTURE; CELLS; CHEMICAL COMPOUNDS; COMMINUTION; DISEASES; GELS; THREE DIMENSIONAL; THROUGHPUT; TISSUE;

SCAFFOLDS (BIOLOGY);

COLLAGEN GEL; POLYMER;

ALGORITHM; ANIMAL CELL; ARTICLE; AUTOMATION; BREAST SARCOMA; CANCER CELL; CANCER INVASION; CANCER SCREENING; CANCER THERAPY; CELL CULTURE; CELL EXPANSION; CELL MIGRATION; CELL SIZE; CELL SUSPENSION; CELL TYPE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; MICROINJECTION; MOUSE; NONHUMAN; PERSONALIZED MEDICINE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REPRODUCIBILITY; SPHEROID CELL; TUMOR BIOPSY;

ANIMALS; CELL LINE, TUMOR; CELL MOVEMENT; EXTRACELLULAR MATRIX; HUMANS; MICE; MICROINJECTIONS; NEOPLASMS; POLYMERS; SPHEROIDS, CELLULAR; TISSUE SCAFFOLDS;

EID: 82855172073     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.09.049     Document Type: Article

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