-
2
-
-
0037844361
-
Pharmacodynamics of NN2211, a novel long acting GLP-1 derivative
-
Agerso H, Vicini P. (2003) Pharmacodynamics of NN2211, a novel long acting GLP-1 derivative. Eur. J. Pharm. Sci. 19:141-50.
-
(2003)
Eur. J. Pharm. Sci
, vol.19
, pp. 141-150
-
-
Agerso, H.1
Vicini, P.2
-
3
-
-
0023104829
-
Truncated glucagon-like peptide I, an insulin-releasing hormone from the distal gut
-
Holst JJ, Orskov C, Nielsen OV, Schwartz TW. (1987) Truncated glucagon-like peptide I, an insulin-releasing hormone from the distal gut. FEBS Lett. 211:169-74.
-
(1987)
FEBS Lett
, vol.211
, pp. 169-174
-
-
Holst, J.J.1
Orskov, C.2
Nielsen, O.V.3
Schwartz, T.W.4
-
4
-
-
0023638829
-
Glucagonlike peptide-1 7-36: A physiological incretin in man
-
Kreymann B, Williams G, Ghatei MA, Bloom SR. (1987) Glucagonlike peptide-1 7-36: a physiological incretin in man. Lancet. 2:1300-4.
-
(1987)
Lancet
, vol.2
, pp. 1300-1304
-
-
Kreymann, B.1
Williams, G.2
Ghatei, M.A.3
Bloom, S.R.4
-
5
-
-
0027533758
-
Truncated GLP-1 (proglucagon 78-107-amide) inhibits gastric and pancreatic functions in man
-
Wettergren A, et al. (1993) Truncated GLP-1 (proglucagon 78-107-amide) inhibits gastric and pancreatic functions in man. Dig. Dis. Sci. 38:665-73.
-
(1993)
Dig. Dis. Sci
, vol.38
, pp. 665-673
-
-
Wettergren, A.1
-
6
-
-
0033021677
-
Energy intake and appetite are suppressed by glucagon-like peptide-1 (GLP-1) in obese men
-
Naslund E, et al. (1999) Energy intake and appetite are suppressed by glucagon-like peptide-1 (GLP-1) in obese men. Int. J. Obes. Relat. Metab. Disord. 23:304-11.
-
(1999)
Int. J. Obes. Relat. Metab. Disord
, vol.23
, pp. 304-311
-
-
Naslund, E.1
-
7
-
-
0032871230
-
GLP-1 slows solid gastric emptying and inhibits insulin, glucagon, and PYY release in humans
-
Naslund E, et al. (1999) GLP-1 slows solid gastric emptying and inhibits insulin, glucagon, and PYY release in humans. Am. J. Physiol. Regul. Integr. Comp. Physiol. 277:R910-16.
-
(1999)
Am. J. Physiol. Regul. Integr. Comp. Physiol
, vol.277
-
-
Naslund, E.1
-
8
-
-
0032908809
-
Initiation of increased pancreatic islet growth in young normoglycemic mice (Umea +/-)
-
Edvell A, Lindstrom P. (1999) Initiation of increased pancreatic islet growth in young normoglycemic mice (Umea +/-). Endocrinology. 140:778-83.
-
(1999)
Endocrinology
, vol.140
, pp. 778-783
-
-
Edvell, A.1
Lindstrom, P.2
-
9
-
-
0030068620
-
Gastric emptying, glucose responses, and insulin secretion after a liquid test meal: Effects of exogenous glucagon-like peptide- 1 (GLP-1)-(7-36) amide in type 2 (noninsulindependent) diabetic patients
-
Willms B, et al. (1996) Gastric emptying, glucose responses, and insulin secretion after a liquid test meal: effects of exogenous glucagon-like peptide- 1 (GLP-1)-(7-36) amide in type 2 (noninsulindependent) diabetic patients. J. Clin. Endocrinol. Metab. 81:327-32.
-
(1996)
J. Clin. Endocrinol. Metab
, vol.81
, pp. 327-332
-
-
Willms, B.1
-
10
-
-
0031033531
-
Nearnormalisation of diurnal glucose concentrations by continuous administration of glucagon-like peptide-1 (GLP-1) in subjects with NIDDM
-
Rachman J, Barrow BA, Levy JC, Turner RC. (1997) Nearnormalisation of diurnal glucose concentrations by continuous administration of glucagon-like peptide-1 (GLP-1) in subjects with NIDDM. Diabetologia. 40:205-11.
-
(1997)
Diabetologia
, vol.40
, pp. 205-211
-
-
Rachman, J.1
Barrow, B.A.2
Levy, J.C.3
Turner, R.C.4
-
11
-
-
1442350411
-
Secretion, degradation, and elimination of glucagon-like peptide 1 and gastric inhibitory polypeptide in patients with chronic renal insufficiency and healthy control subjects
-
Meier JJ, et al. (2004) Secretion, degradation, and elimination of glucagon-like peptide 1 and gastric inhibitory polypeptide in patients with chronic renal insufficiency and healthy control subjects. Diabetes. 53:654-62.
-
(2004)
Diabetes
, vol.53
, pp. 654-662
-
-
Meier, J.J.1
-
12
-
-
0034108646
-
Potent derivatives of glucagon-like peptide-1 with pharmacokinetic properties suitable for once daily administration
-
Knudsen LB, et al. (2000) Potent derivatives of glucagon-like peptide-1 with pharmacokinetic properties suitable for once daily administration. J. Med. Chem. 43:1664-9.
-
(2000)
J. Med. Chem
, vol.43
, pp. 1664-1669
-
-
Knudsen, L.B.1
-
13
-
-
0031695395
-
Glucagon-like peptide 1 increases the period of postprandial satiety and slows gastric emptying in obese men
-
Naslund E, Gutniak M, Skogar S, Rossner S, Hellstrom PM. (1998) Glucagon-like peptide 1 increases the period of postprandial satiety and slows gastric emptying in obese men. Am. J. Clin. Nutr. 68:525-30.
-
(1998)
Am. J. Clin Nutr
, vol.68
, pp. 525-530
-
-
Naslund, E.1
Gutniak, M.2
Skogar, S.3
Rossner, S.4
Hellstrom, P.M.5
-
14
-
-
15744381238
-
The long-acting glucagonlike peptide-1 analogue, liraglutide, inhibits beta-cell apoptosis in vitro
-
Bregenholt S, et al. (2005) The long-acting glucagonlike peptide-1 analogue, liraglutide, inhibits beta-cell apoptosis in vitro. Biochem. Biophys. Res. Commun. 330:577-84.
-
(2005)
Biochem. Biophys Res. Commun
, vol.330
, pp. 577-584
-
-
Bregenholt, S.1
-
15
-
-
34547684649
-
Effects of the long-acting human glucagon-like peptide-1 analog liraglutide on beta-cell function in normal living conditions
-
Mari A, et al. (2007) Effects of the long-acting human glucagon-like peptide-1 analog liraglutide on beta-cell function in normal living conditions. Diabetes Care. 30:2032-3.
-
(2007)
Diabetes Care
, vol.30
, pp. 2032-2033
-
-
Mari, A.1
-
16
-
-
15744381238
-
The long-acting glucagonlike peptide-1 analogue, liraglutide, inhibits beta-cell apoptosis in vitro
-
Bregenholt S, et al. (2005) The long-acting glucagonlike peptide-1 analogue, liraglutide, inhibits beta-cell apoptosis in vitro. Biochem. Biophys. Res. Commun. 330:577-84.
-
(2005)
Biochem. Biophys. Res. Commun
, vol.330
, pp. 577-584
-
-
Bregenholt, S.1
-
17
-
-
52449129375
-
Exenatide prevents fat-induced insulin resistance and raises adiponectin expression and plasma levels
-
Li L, et al. (2008) Exenatide prevents fat-induced insulin resistance and raises adiponectin expression and plasma levels. Diabetes Obes. Metab. 10:921-30.
-
(2008)
Diabetes Obes. Metab
, vol.10
, pp. 921-930
-
-
Li, L.1
-
18
-
-
77951870446
-
Effect of short hairpin RNAmediated adiponectin/Acrp30 down-regulation on insulin signaling and glucose uptake in the 3T3-L1 adipocytes
-
Li K, et al. (2010) Effect of short hairpin RNAmediated adiponectin/Acrp30 down-regulation on insulin signaling and glucose uptake in the 3T3-L1 adipocytes. J. Endocrinol. Invest. 33:96-102.
-
(2010)
J. Endocrinol. Invest
, vol.33
, pp. 96-102
-
-
Li, K.1
-
19
-
-
57749105202
-
The adipose triglyceride lipase, adiponectin and visfatin are downregulated by tumor necrosis factor-α (TNF-α) in vivo
-
Ling L, et al. (2009) The adipose triglyceride lipase, adiponectin and visfatin are downregulated by tumor necrosis factor-α (TNF-α) in vivo. Cytokine. 45:12-9.
-
(2009)
Cytokine
, vol.45
, pp. 12-19
-
-
Ling, L.1
-
20
-
-
77049274176
-
Measurement of size and turnover rate of body glucose pool by the isotope dilution method
-
Steele R, Wall JS, DeBodo RC. (1956) Measurement of size and turnover rate of body glucose pool by the isotope dilution method. Am. J. Physiol. 187:15-24.
-
(1956)
Am. J. Physiol
, vol.187
, pp. 15-24
-
-
Steele, R.1
Wall, J.S.2
Debodo, R.C.3
-
21
-
-
82855182862
-
The changes of glucose-lipid metabolism in ApoE-/- mice with high-fat induced insulin resistance
-
Yu C, Gangyi Y, Ling L, Ling K, Wenwen C. (2009) The changes of glucose-lipid metabolism in ApoE-/- mice with high-fat induced insulin resistance. Chinese J. Diabetes. 17:590-603.
-
(2009)
Chinese J. Diabetes
, vol.17
, pp. 590-603
-
-
Yu, C.1
Gangyi, Y.2
Ling, L.3
Ling, K.4
Wenwen, C.5
-
22
-
-
0033061486
-
GLUT-1 or GLUT-4 transgenes in obese mice improve glucose tolerance but do not prevent insulin resistance
-
Marshall BA, Hansen PA, Ensor NJ, Ogden MA, Mueckler M. (1999) GLUT-1 or GLUT-4 transgenes in obese mice improve glucose tolerance but do not prevent insulin resistance. Am. J. Physiol. Endocrinol. Metab. 276:390-400.
-
(1999)
Am. J. Physiol. Endocrinol. Metab
, vol.276
, pp. 390-400
-
-
Marshall, B.A.1
Hansen, P.A.2
Ensor, N.J.3
Ogden, M.A.4
Mueckler, M.5
-
23
-
-
0028809238
-
Decreased muscle glucose transport/phosphorylation is an early defect in the pathogenesis of non-insulin-dependent diabetes mellitus
-
Rothman DL, et al. (1995) Decreased muscle glucose transport/phosphorylation is an early defect in the pathogenesis of non-insulin-dependent diabetes mellitus. Proc. Natl. Acad. Sci. U. S. A. 92:983-7.
-
(1995)
Proc. Natl. Acad. Sci. U. S. A
, vol.92
, pp. 983-987
-
-
Rothman, D.L.1
-
24
-
-
10644256593
-
Role of the liver in the control of carbohydrate and lipid homeostasis
-
Postic C, Dentin R, Girard J. (2004) Role of the liver in the control of carbohydrate and lipid homeostasis. Diabetes Metab. 30:398-408.
-
(2004)
Diabetes Metab
, vol.30
, pp. 398-408
-
-
Postic, C.1
Dentin, R.2
Girard, J.3
-
25
-
-
0036794551
-
Hormone-sensitive lipase: Control of intracellular tri-(di-) acylglycerol and cholesteryl ester hydrolysis
-
Kraemer FB, Shen WJ. (2002) Hormone-sensitive lipase: control of intracellular tri-(di-) acylglycerol and cholesteryl ester hydrolysis. J. Lipid Res. 43:1585-94.
-
(2002)
J. Lipid Res
, vol.43
, pp. 1585-1594
-
-
Kraemer, F.B.1
Shen, W.J.2
-
26
-
-
0344667491
-
Decreased fatty acid esterification compensates for the reduced lipolytic activity in hormone- sensitive lipase-deficient white adipose tissue
-
Zimmermann R, et al. (2003) Decreased fatty acid esterification compensates for the reduced lipolytic activity in hormone- sensitive lipase-deficient white adipose tissue. J. Lipid Res. 44:2089-99.
-
(2003)
J. Lipid Res
, vol.44
, pp. 2089-2099
-
-
Zimmermann, R.1
-
27
-
-
0037312845
-
PPAR-γ activation mediates adipose depot-specific effects on gene expression and lipoprotein lipase activity
-
Laplante M, et al. (2003) PPAR-γ activation mediates adipose depot-specific effects on gene expression and lipoprotein lipase activity. Diabetes. 52:291-9.
-
(2003)
Diabetes
, vol.52
, pp. 291-299
-
-
Laplante, M.1
-
28
-
-
1542283630
-
Peroxisome proliferator-activated receptor alpha target genes
-
Mandard S, Muller M, Kersten S. (2004) Peroxisome proliferator-activated receptor alpha target genes. Cell. Mol. Life Sci. 61:393-416.
-
(2004)
Cell. Mol. Life Sci
, vol.61
, pp. 393-416
-
-
Mandard, S.1
Muller, M.2
Kersten, S.3
-
29
-
-
3142580930
-
The peroxisome proliferatoractivated receptor α (PPARα) agonist ciprofibrate inhibits apolipoprotein B mRNA editing in low density lipoprotein receptor-deficient mice
-
Fu T, Mukhopadhyay D, Davidson NO, Borensztajn J. (2004) The peroxisome proliferatoractivated receptor α (PPARα) agonist ciprofibrate inhibits apolipoprotein B mRNA editing in low density lipoprotein receptor-deficient mice. J. Biol. Chem. 279:28662-9.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 28662-28669
-
-
Fu, T.1
Mukhopadhyay, D.2
Davidson, N.O.3
Borensztajn, J.4
-
30
-
-
43249085693
-
Insulin-induced gene 2 involvement in human adipocyte metabolism and body weight regulation
-
Krapivner S, et al. (2008) Insulin-induced gene 2 involvement in human adipocyte metabolism and body weight regulation. J. Clin. Endocrinol. Metab. 93:1995-2001.
-
(2008)
J. Clin. Endocrinol Metab
, vol.93
, pp. 1995-2001
-
-
Krapivner, S.1
-
31
-
-
0036251153
-
SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
-
Horton JD, Goldstein JL, Brown MS. (2002) SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J. Clin. Invest. 109:1125-31.
-
(2002)
J. Clin. Invest
, vol.109
, pp. 1125-1131
-
-
Horton, J.D.1
Goldstein, J.L.2
Brown, M.S.3
-
32
-
-
0037162719
-
Crucial step in cholesterol homeostasis: Sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER
-
Yang T, et al. (2002) Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER. Cell. 110:489-500.
-
(2002)
Cell
, vol.110
, pp. 489-500
-
-
Yang, T.1
-
33
-
-
0036792050
-
Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins
-
Yabe D, Brown MS, Goldstein JL. (2002) Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins. Proc. Natl. Acad. Sci. U. S. A. 99:12753-8.
-
(2002)
Proc. Natl. Acad Sci. U. S. A
, vol.99
, pp. 12753-12758
-
-
Yabe, D.1
Brown, M.S.2
Goldstein, J.L.3
-
34
-
-
0037411269
-
Structural and functional organization of the animal fatty acid synthase
-
Smith S, Witkowski A, Joshi AK. (2003) Structural and functional organization of the animal fatty acid synthase. Prog. Lipid Res. 42:289-317.
-
(2003)
Prog. Lipid Res
, vol.42
, pp. 289-317
-
-
Smith, S.1
Witkowski, A.2
Joshi, A.K.3
|