메뉴 건너뛰기




Volumn 301, Issue 6, 2011, Pages

Programmatic change:Lung disease research in the era of induced pluripotency

Author keywords

BMPR2; Bone morphogenetic protein receptor type 2; iPSCs; Pulmonary arterial hypertension

Indexed keywords

ARTICLE; HUMAN; LUNG DISEASE; MEDICAL RESEARCH; NONHUMAN; PATHOPHYSIOLOGY; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PULMONARY HYPERTENSION; PULMONARY VASCULAR DISEASE;

EID: 82855167239     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00255.2011     Document Type: Article
Times cited : (5)

References (64)
  • 1
    • 0037046175 scopus 로고    scopus 로고
    • Primary pulmonary hypertension is associated with reduced pulmonary vascular expression of type II bone morphogenetic protein receptor
    • Atkinson C, Stewart S, Upton PD, Machado R, Thomson JR, Trembath RC, Morrell NW. Primary pulmonary hypertension is associated with reduced pulmonary vascular expression of type II bone morphogenetic protein receptor. Circulation 105:1672-1678, 2002.
    • (2002) Circulation , vol.105 , pp. 1672-1678
    • Atkinson, C.1    Stewart, S.2    Upton, P.D.3    Machado, R.4    Thomson, J.R.5    Trembath, R.C.6    Morrell, N.W.7
  • 5
    • 0033219861 scopus 로고    scopus 로고
    • Cell-based gene transfer to the pulmonary vasculature:Endothelial nitric oxide synthase overexpression inhibits monocrotaline-induced pulmonary hypertension
    • Campbell AI, Kuliszewski MA, Stewart DJ. Cell-based gene transfer to the pulmonary vasculature: Endothelial nitric oxide synthase overexpression inhibits monocrotaline-induced pulmonary hypertension. Am J Respir Cell Mol Biol 21:567-575, 1999.
    • (1999) Cell Mol Biol , vol.21 , pp. 567-575
    • Campbell, A.I.1    Kuliszewski, M.A.2    Stewart, D.J.3
  • 8
    • 69249208658 scopus 로고    scopus 로고
    • Pluripotent stem cells and disease modeling
    • Colman A, Dreesen O. Pluripotent stem cells and disease modeling. Cell Stem Cell 5:244-247, 2009.
    • (2009) Cell Stem Cell , vol.5 , pp. 244-247
    • Colman, A.1    Dreesen, O.2
  • 9
    • 0033753747 scopus 로고    scopus 로고
    • Genetics of asthma and allergic disease
    • Cookson WO, Moffatt MF. Genetics of asthma and allergic disease. Hum Mol Genet 9: 2359-2364, 2000.
    • (2000) Hum Mol Genet , vol.9 , pp. 2359-2364
    • Cookson, W.O.1    Moffatt, M.F.2
  • 12
    • 67649920749 scopus 로고    scopus 로고
    • Growth factors, matrices, and forces combine and control stem cells
    • Discher DE, Mooney DJ, Zandstra PW. Growth factors, matrices, and forces combine and control stem cells. Science 324:1673-1677, 2009.
    • (2009) Science , vol.324 , pp. 1673-1677
    • Discher, D.E.1    Mooney, D.J.2    Zandstra, P.W.3
  • 13
    • 0019826665 scopus 로고
    • Establishment in culture of pluripotential cells from mouse embryos
    • Evans MJ, Kaufman MH. Establishment in culture of pluripotential cells from mouse embryos. Nature 292: 154-156, 1981.
    • (1981) Nature , vol.292 , pp. 154-156
    • Evans, M.J.1    Kaufman, M.H.2
  • 14
    • 5344233478 scopus 로고    scopus 로고
    • Pulmonary arterial hypertension
    • Farber HW, Loscalzo J. Pulmonary arterial hypertension. N Engl J Med 351:1655-1665, 2004.
    • (2004) N Engl J Med , vol.351 , pp. 1655-1665
    • Farber, H.W.1    Loscalzo, J.2
  • 20
    • 79955464098 scopus 로고    scopus 로고
    • The use of induced pluripotent stem cells in drug development
    • Inoue H, Yamanaka S. The use of induced pluripotent stem cells in drug development. Clin Pharmacol Ther 89:655-661, 2011.
    • (2011) Clin Pharmacol Ther , vol.89 , pp. 655-661
    • Inoue, H.1    Yamanaka, S.2
  • 23
    • 33747186449 scopus 로고    scopus 로고
    • Implantation of mesenchymal stem cells overexpressing endothelial nitric oxide synthase improves right ventricular impairments caused by pulmonary hypertension
    • Kanki-Horimoto S, Horimoto H, Mieno S, Kishida K, Watanabe F, Furuya E, Katsumata T. Implantation of mesenchymal stem cells overexpressing endothelial nitric oxide synthase improves right ventricular impairments caused by pulmonary hypertension. Circulation 114:I181-I185, 2006.
    • (2006) Circulation , vol.114
    • Kanki-Horimoto, S.1    Horimoto, H.2    Mieno, S.3    Kishida, K.4    Watanabe, F.5    Furuya, E.6    Katsumata, T.7
  • 25
    • 33750456216 scopus 로고    scopus 로고
    • Multipotent Flk-1_ cardiovascular progenitor cells give rise to the cardiomyocyte, endothelial, and vascular smooth muscle lineages
    • Kattman SJ, Huber TL, Keller GM. Multipotent Flk-1_ cardiovascular progenitor cells give rise to the cardiomyocyte, endothelial, and vascular smooth muscle lineages. Dev Cell 11:723-732, 2006.
    • (2006) Dev Cell , vol.11 , pp. 723-732
    • Kattman, S.J.1    Huber, T.L.2    Keller, G.M.3
  • 26
    • 33748580104 scopus 로고    scopus 로고
    • Human embryonic stem cell lines derived from single blastomeres
    • Klimanskaya I, Chung Y, Becker S, Lu SJ, Lanza R. Human embryonic stem cell lines derived from single blastomeres. Nature 444:481-485, 2006.
    • (2006) Nature , vol.444 , pp. 481-485
    • Klimanskaya, I.1    Chung, Y.2    Becker, S.3    Lu, S.J.4    Lanza, R.5
  • 27
    • 33744935773 scopus 로고    scopus 로고
    • The genetic approach in pulmonary fibrosis:Can it provide clues to this complex disease?
    • Lawson WE, Loyd JE. The genetic approach in pulmonary fibrosis: can it provide clues to this complex disease? Proc Am Thorac Soc 3:345-349, 2006.
    • (2006) Proc Am Thorac Soc , vol.3 , pp. 345-349
    • Lawson, W.E.1    Loyd, J.E.2
  • 28
    • 70349301819 scopus 로고    scopus 로고
    • Tomishima MJ,Fasano CA, Ganat YM, Menon J, Shimizu F, Viale A, Tabar V,Sadelain M, Studer L.Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs
    • Lee G, Papapetrou EP, Kim H, Chambers SM, Tomishima MJ,Fasano CA, Ganat YM, Menon J, Shimizu F, Viale A, Tabar V,Sadelain M, Studer L. Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs. Nature 461:402-406, 2009.
    • (2009) Nature , vol.461 , pp. 402-406
    • Lee, G.1    Papapetrou, E.P.2    Kim, H.3    Chambers, S.M.4
  • 29
    • 13844271605 scopus 로고    scopus 로고
    • Pearce RA,Zhang SC.Specification of motoneurons from human embryonic stem cells
    • Li XJ, Du ZW, Zarnowska ED, Pankratz M, Hansen LO, Pearce RA,Zhang SC. Specification of motoneurons from human embryonic stem cells. Nat Biotechnol 23:215-221, 2005.
    • (2005) Nat Biotechnol , vol.23 , pp. 215-221
    • Li, X.J.1    Du, Z.W.2    Zarnowska, E.D.3    Pankratz, M.4    Hansen, L.O.5
  • 33
  • 34
    • 30544449468 scopus 로고    scopus 로고
    • Generation of nuclear transfer-derived pluripotent ES cells from cloned Cdx2-deficient blastocysts
    • Meissner A, Jaenisch R. Generation of nuclear transfer-derived pluripotent ES cells from cloned Cdx2-deficient blastocysts. Nature 439:212-215, 2006.
    • (2006) Nature , vol.439 , pp. 212-215
    • Meissner, A.1    Jaenisch, R.2
  • 37
    • 39349106325 scopus 로고    scopus 로고
    • Differentiation of embryonic stem cells to clinically relevant populations:Lessons from embryonic development
    • Murry CE, Keller G. Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development. Cell 132:661-680, 2008.
    • (2008) Cell , vol.132 , pp. 661-680
    • Murry, C.E.1    Keller, G.2
  • 45
    • 4544386270 scopus 로고    scopus 로고
    • Barst RJ,Knowles JA, Morse JH.BMPR2 mutations in pulmonary arterial hypertension with congenital heart disease
    • Roberts KE, McElroy JJ, Wong WP, Yen E, Widlitz A, Barst RJ,Knowles JA, Morse JH. BMPR2 mutations in pulmonary arterial hypertension with congenital heart disease. Eur Respir J 24:371-374, 2004.
    • (2004) Eur Respir J , vol.24 , pp. 371-374
    • Roberts, K.E.1    McElroy, J.J.2    Wong, W.P.3    Yen, E.4    Widlitz, A.5
  • 47
    • 0037623284 scopus 로고    scopus 로고
    • Primary pulmonary hypertension
    • Runo JR, Loyd JE. Primary pulmonary hypertension. Lancet 361: 1533-1544,2003.
    • (2003) Lancet , vol.361 , pp. 1533-1544
    • Runo, J.R.1    Loyd, J.E.2
  • 48
    • 70450285340 scopus 로고    scopus 로고
    • Technical challenges in using human induced pluripotent stem cells to model disease
    • Saha K, Jaenisch R. Technical challenges in using human induced pluripotent stem cells to model disease. Cell Stem Cell 5:584-595, 2009.
    • (2009) Cell Stem Cell , vol.5 , pp. 584-595
    • Saha, K.1    Jaenisch, R.2
  • 49
    • 79960649307 scopus 로고    scopus 로고
    • Direct conversion of mouse fibroblasts to hepatocytelike cells by defined factors
    • Sekiya S, Suzuki A. Direct conversion of mouse fibroblasts to hepatocytelike cells by defined factors. Nature 475:390-393, 2011.
    • (2011) Nature , vol.475 , pp. 390-393
    • Sekiya, S.1    Suzuki, A.2
  • 52
    • 77953159822 scopus 로고    scopus 로고
    • Human iPS cell-based therapy:Considerations before clinical applications
    • Sun N, Longaker MT, Wu JC. Human iPS cell-based therapy: considerations before clinical applications. Cell Cycle 9:880-885.
    • Cell Cycle , vol.9 , pp. 880-885
    • Sun, N.1    Longaker, M.T.2    Wu, J.C.3
  • 54
    • 36248966518 scopus 로고    scopus 로고
    • Tomoda K,Yamanaka S.Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K,Yamanaka S. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131:861-872, 2007.
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Narita, M.4    Ichisaka, T.5
  • 55
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126:663-76, 2006.
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 57
    • 79951987330 scopus 로고    scopus 로고
    • Endothelial progenitor cells in pulmonary hypertension - dawn of cell-based therapy?
    • Toshner M, Morrell NW. Endothelial progenitor cells in pulmonary hypertension - dawn of cell-based therapy? Int J Clin Pract Suppl 165:7-12, 2011.
    • (2011) Int J Clin Pract Suppl , vol.165 , pp. 7-12
    • Toshner, M.1    Morrell, N.W.2
  • 58
    • 34047098378 scopus 로고    scopus 로고
    • Role of bone morphogenetic proteins in cardiac differentiation
    • van Wijk B, Moorman AF, van den Hoff MJ. Role of bone morphogenetic proteins in cardiac differentiation. Cardiovasc Res 74:244-255, 2007.
    • (2007) Cardiovasc Res , vol.74 , pp. 244-255
    • van Wijk, B.1    Moorman, A.F.2    van den Hoff, M.J.3
  • 59
    • 77649162059 scopus 로고    scopus 로고
    • Sudhof TC,Wernig M.Direct conversion of fibroblasts to functional neurons by defined factors
    • Vierbuchen T, Ostermeier A, Pang ZP, Kokubu Y, Sudhof TC,Wernig M. Direct conversion of fibroblasts to functional neurons by defined factors. Nature 463:1035-1041, 2010.
    • (2010) Nature , vol.463 , pp. 1035-1041
    • Vierbuchen, T.1    Ostermeier, A.2    Pang, Z.P.3    Kokubu, Y.4
  • 60
    • 44349175948 scopus 로고    scopus 로고
    • Kennedy M,Henckaerts E, Bonham K, Abbott GW, Linden RM, Field LJ, Keller GM.Human cardiovascular progenitor cells develop from a KDR_embryonicstem-cell-derived population
    • Yang L, Soonpaa MH, Adler ED, Roepke TK, Kattman SJ, Kennedy M,Henckaerts E, Bonham K, Abbott GW, Linden RM, Field LJ, Keller GM. Human cardiovascular progenitor cells develop from a KDR_ embryonicstem-cell-derived population. Nature 453:524-528, 2008.
    • (2008) Nature , vol.453 , pp. 524-528
    • Yang, L.1    Soonpaa, M.H.2    Adler, E.D.3    Roepke, T.K.4    Kattman, S.J.5
  • 63
    • 34447570619 scopus 로고    scopus 로고
    • Effect of preprocalcitonin gene-related peptide-expressing endothelial progenitor cells on pulmonary hypertension
    • Zhao Q, Liu Z, Wang Z, Yang C, Liu J, Lu J. Effect of preprocalcitonin gene-related peptide-expressing endothelial progenitor cells on pulmonary hypertension. Ann Thorac Surg 84:544-552, 2007.
    • (2007) Ann Thorac Surg , vol.84 , pp. 544-552
    • Zhao, Q.1    Liu, Z.2    Wang, Z.3    Yang, C.4    Liu, J.5    Lu, J.6
  • 64
    • 14844360656 scopus 로고    scopus 로고
    • Rescue of monocrotaline-induced pulmonary arterial hypertension using bone marrow derived endothelial-like progenitor cells:Efficacy of combined cell and eNOS gene therapy in established disease
    • Zhao YD, Courtman DW, Deng Y, Kugathasan L, Zhang Q, Stewart DJ. Rescue of monocrotaline-induced pulmonary arterial hypertension using bone marrow derived endothelial-like progenitor cells: efficacy of combined cell and eNOS gene therapy in established disease. Circ Res 96:442-450, 2005.
    • (2005) Circ Res , vol.96 , pp. 442-450
    • Zhao, Y.D.1    Courtman, D.W.2    Deng, Y.3    Kugathasan, L.4    Zhang, Q.5    Stewart, D.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.