-
1
-
-
0025120211
-
Regulation of the mevalonate pathway
-
Goldstein, J. L.; Brown, M. S. Regulation of the mevalonate pathway Nature 1990, 343, 425-430
-
(1990)
Nature
, vol.343
, pp. 425-430
-
-
Goldstein, J.L.1
Brown, M.S.2
-
2
-
-
0037069690
-
Rho GTPases in cell biology
-
DOI 10.1038/nature01148
-
Etienne-Manneville, S.; Hall, A. Rho GTPases in cell biology Nature 2002, 420, 629-635 (Pubitemid 36764489)
-
(2002)
Nature
, vol.420
, Issue.6916
, pp. 629-635
-
-
Etienne-Manneville, S.1
Hall, A.2
-
3
-
-
0036239832
-
HMG-CoA reductase inhibitors and the malignant cell: The statin family of drugs as triggers of tumor-specific apoptosis
-
DOI 10.1038/sj/leu/2402476
-
Wong, W. W.; Dimitroulakos, J.; Minden, M. D.; Penn, L. Z. HMG-CoA reductase inhibitors and the malignant cell: the statin family of drugs as triggers of tumor-specific apoptosis Leukemia 2002, 16, 508-519 (Pubitemid 34460459)
-
(2002)
Leukemia
, vol.16
, Issue.4
, pp. 508-519
-
-
Wong, W.W.-L.1
Dimitroulakos, J.2
Minden, M.D.3
Penn, L.Z.4
-
4
-
-
0037233011
-
The statins as anticancer agents
-
Chan, K. K.; Oza, A. M.; Siu, L. L. The statins as anticancer agents Clin. Cancer Res. 2003, 9, 10-19 (Pubitemid 36109711)
-
(2003)
Clinical Cancer Research
, vol.9
, Issue.1
, pp. 10-19
-
-
Chan, K.K.W.1
Oza, A.M.2
Siu, L.L.3
-
5
-
-
28844490054
-
Statins and cancer prevention
-
DOI 10.1038/nrc1751
-
Demierre, M. F.; Higgins, P. D.; Gruber, S. B.; Hawk, E.; Lippman, S. M. Statins and cancer prevention Nat. Rev. Cancer 2005, 5, 930-942 (Pubitemid 41766782)
-
(2005)
Nature Reviews Cancer
, vol.5
, Issue.12
, pp. 930-942
-
-
Demierre, M.-F.1
Higgins, P.D.R.2
Gruber, S.B.3
Hawk, E.4
Lippman, S.M.5
-
6
-
-
0032875697
-
Quantitative analysis of complex protein mixtures using isotope-coded affinity tags
-
DOI 10.1038/13690
-
Gygi, S. P.; Rist, B.; Gerber, S. A.; Turecek, F.; Gelb, M. H.; Aebersold, R. Quantitative analysis of complex protein mixtures using isotope-coded affinity tags Nat. Biotechnol. 1999, 17, 994-999 (Pubitemid 29474856)
-
(1999)
Nature Biotechnology
, vol.17
, Issue.10
, pp. 994-999
-
-
Gygi, S.P.1
Rist, B.2
Gerber, S.A.3
Turecek, F.4
Gelb, M.H.5
Aebersold, R.6
-
7
-
-
19944432197
-
Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents
-
Ross, P. L. H., Y. N.; Marchese, J. N.; Williamson, B.; Parker, K.; Hattan, S.; Khainovski, N.; Pillai, S.; Dey, S.; Daniels, S.; Purkayastha, S.; Juhasz, P.; Martin, S.; Bartlet-Jones, M.; He, F.; Jacobson, A.; Pappin, D. J. Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents Mol. Cell. Proteomics 2004, 3, 1154-1169
-
(2004)
Mol. Cell. Proteomics
, vol.3
, pp. 1154-1169
-
-
Ross, P.L.H..Y.N.1
Marchese, J.N.2
Williamson, B.3
Parker, K.4
Hattan, S.5
Khainovski, N.6
Pillai, S.7
Dey, S.8
Daniels, S.9
Purkayastha, S.10
Juhasz, P.11
Martin, S.12
Bartlet-Jones, M.13
He, F.14
Jacobson, A.15
Pappin, D.J.16
-
8
-
-
0036583926
-
Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics
-
Ong, S. E.; Blagoev, B.; Kratchmarova, I.; Kristensen, D. B.; Steen, H.; Pandey, A.; Mann, M. Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics Mol. Cell. Proteomics 2002, 1, 376-386
-
(2002)
Mol. Cell. Proteomics
, vol.1
, pp. 376-386
-
-
Ong, S.E.1
Blagoev, B.2
Kratchmarova, I.3
Kristensen, D.B.4
Steen, H.5
Pandey, A.6
Mann, M.7
-
9
-
-
0033557949
-
Increased sensitivity of acute myeloid leukemias to lovastatin-induced apoptosis: A potential therapeutic approach
-
Dimitroulakos, J.; Nohynek, D.; Backway, K. L.; Hedley, D. W.; Yeger, H.; Freedman, M. H.; Minden, M. D.; Penn, L. Z. Increased sensitivity of acute myeloid leukemias to lovastatin-induced apoptosis: A potential therapeutic approach Blood 1999, 93, 1308-1318 (Pubitemid 29076146)
-
(1999)
Blood
, vol.93
, Issue.4
, pp. 1308-1318
-
-
Dimitroulakos, J.1
Nohynek, D.2
Backway, K.L.3
Medley, D.W.4
Yeger, H.5
Freedman, M.H.6
Minden, M.D.7
Penn, L.Z.8
-
10
-
-
0028917643
-
Intracellular alkalinization suppresses lovastatin-induced apoptosis in HL-60 cells through the inactivation of a pH-dependent endonuclease
-
Perezsala, D.; Colladoescobar, D.; Mollinedo, F. Intracellular alkalinization suppresses lovastatin-induced apoptosis in HL-60 cells through the inactivation of a pH-dependent endonuclease J. Biol. Chem. 1995, 270, 6235-6242
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 6235-6242
-
-
Perezsala, D.1
Colladoescobar, D.2
Mollinedo, F.3
-
11
-
-
57449099865
-
MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification
-
Cox, J.; Mann, M. MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification Nat. Biotechnol. 2008, 26, 1367-1372
-
(2008)
Nat. Biotechnol.
, vol.26
, pp. 1367-1372
-
-
Cox, J.1
Mann, M.2
-
12
-
-
78751496279
-
Proteomic snapshot of the EGF-induced ubiquitin network
-
Argenzio, E.; Bange, T.; Oldrini, B.; Bianchi, F.; Peesari, R.; Mari, S.; Di Fiore, P. P.; Mann, M.; Polo, S. Proteomic snapshot of the EGF-induced ubiquitin network Mol. Syst. Biol. 2011, 7, 462
-
(2011)
Mol. Syst. Biol.
, vol.7
, pp. 462
-
-
Argenzio, E.1
Bange, T.2
Oldrini, B.3
Bianchi, F.4
Peesari, R.5
Mari, S.6
Di Fiore, P.P.7
Mann, M.8
Polo, S.9
-
13
-
-
65249113798
-
Stable Isotope Dilution Multidimensional Liquid Chromatography-Tandem Mass Spectrometry for Pancreatic Cancer Serum Biomarker Discovery
-
Yu, K. H.; Barry, C. G.; Austin, D.; Busch, C. M.; Sangar, V.; Rustgi, A. K.; Blair, I. A. Stable Isotope Dilution Multidimensional Liquid Chromatography-Tandem Mass Spectrometry for Pancreatic Cancer Serum Biomarker Discovery J. Proteome Res. 2009, 8, 1565-1576
-
(2009)
J. Proteome Res.
, vol.8
, pp. 1565-1576
-
-
Yu, K.H.1
Barry, C.G.2
Austin, D.3
Busch, C.M.4
Sangar, V.5
Rustgi, A.K.6
Blair, I.A.7
-
14
-
-
76149138039
-
Quantitative proteomic analysis reveals the perturbation of multiple cellular pathways in HL-60 cells induced by arsenite treatment
-
Xiong, L.; Wang, Y. S. Quantitative proteomic analysis reveals the perturbation of multiple cellular pathways in HL-60 cells induced by arsenite treatment J. Proteome Res. 2010, 9, 1129-1137
-
(2010)
J. Proteome Res.
, vol.9
, pp. 1129-1137
-
-
Xiong, L.1
Wang, Y.S.2
-
15
-
-
0020265803
-
Cholesterol synthesis in polyclonally activated cytotoxic lymphocytes and its requirement for differentiation and proliferation
-
DOI 10.1073/pnas.79.12.3823
-
Heiniger, H. J.; Marshall, J. D. Cholesterol synthesis in polyclonally activated cytotoxic lymphocytes and its requirement for differentiation and proliferation Proc. Natl. Acad. Sci. U.S.A. 1982, 79, 3823-3827 (Pubitemid 12013551)
-
(1982)
Proceedings of the National Academy of Sciences of the United States of America
, vol.79
, Issue.12
, pp. 3823-3827
-
-
Heiniger, H.J.1
Marshall, J.D.2
-
16
-
-
0032426171
-
The biosynthesis of steroids and triterpenoids
-
Brown, G. D. The biosynthesis of steroids and triterpenoids Nat. Prod. Rep. 1998, 15, 653-696 (Pubitemid 29025682)
-
(1998)
Natural Product Reports
, vol.15
, Issue.6
, pp. 653-696
-
-
Brown, G.D.1
-
17
-
-
17744373463
-
A subfamily of RNA-binding DEAD-box proteins acts as an estrogen receptor coactivator through the N-terminal activation domain (AF-1) with an RNA coactivator, SRA
-
DOI 10.1093/emboj/20.6.1341
-
Watanabe, M.; Yanagisawa, J.; Kitagawa, H.; Takeyama, K.; Ogawa, S.; Arao, Y.; Suzawa, M.; Kobayashi, Y.; Yano, T.; Yoshikawa, H.; Masuhiro, Y.; Kato, S. A subfamily of RNA-binding DEAD-box proteins acts as an estrogen receptor alpha coactivator through the N-terminal activation domain (AF-1) with an RNA coactivator, SRA EMBO J. 2001, 20, 1341-1352 (Pubitemid 32233974)
-
(2001)
EMBO Journal
, vol.20
, Issue.6
, pp. 1341-1352
-
-
Watanabe, M.1
Yanagisawa, J.2
Kitagawa, H.3
Takeyama, K.-I.4
Ogawa, S.5
Arao, Y.6
Suzawa, M.7
Kobayashi, Y.8
Yano, T.9
Yoshikawa, H.10
Masuhiro, Y.11
Kato, S.12
-
18
-
-
76849105477
-
Steroid receptor RNA activator protein (SRAP): A potential new prognostic marker for estrogen receptor-positive/node-negative/younger breast cancer patients
-
Yan, Y.; Skliris, G. P.; Penner, C. C.; Chooniedass-Kothari, S.; Cooper, C.; Nugent, Z.; Fristenski, A.; Hamedani, M. K.; Blanchard, A.; Myal, Y.; Murphy, L. C.; Leygue, E. Steroid receptor RNA activator protein (SRAP): A potential new prognostic marker for estrogen receptor-positive/node-negative/ younger breast cancer patients Cancer Res. 2009, 69, 597S-597S
-
(2009)
Cancer Res.
, vol.69
-
-
Yan, Y.1
Skliris, G.P.2
Penner, C.C.3
Chooniedass-Kothari, S.4
Cooper, C.5
Nugent, Z.6
Fristenski, A.7
Hamedani, M.K.8
Blanchard, A.9
Myal, Y.10
Murphy, L.C.11
Leygue, E.12
-
19
-
-
0026785545
-
Immunological detection of the oestradiol receptor protein in cell lines derived from the lymphatic system and the haematopoietic system: Variability of specific hormone binding in vitro
-
Jakob, F.; Tony, H. P.; Schneider, D.; Thole, H. H. Immunological detection of the oestradiol receptor protein in cell lines derived from the lymphatic system and the haematopoietic system: variability of specific hormone binding in vitro J. Endocrinol. 1992, 134, 397-404
-
(1992)
J. Endocrinol.
, vol.134
, pp. 397-404
-
-
Jakob, F.1
Tony, H.P.2
Schneider, D.3
Thole, H.H.4
-
20
-
-
0033535424
-
Estrogen, DNA damage and mutations
-
DOI 10.1016/S0027-5107(99)00012-3, PII S0027510799000123
-
Roy, D.; Liehr, J. G. Estrogen, DNA damage and mutations Mutat. Res.-Fundam. Mol. Mech. Mutagen. 1999, 424, 107-115 (Pubitemid 29101612)
-
(1999)
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
, vol.424
, Issue.1-2
, pp. 107-115
-
-
Roy, D.1
Liehr, J.G.2
-
21
-
-
15544365329
-
Selective estrogen-receptor modulators for primary prevention of breast cancer
-
DOI 10.1200/JCO.2005.11.005
-
Fabian, C. J.; Kimler, B. F. Selective estrogen-receptor modulators for primary prevention of breast cancer J. Clin. Oncol. 2005, 23, 1644-1655 (Pubitemid 46211419)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.8
, pp. 1644-1655
-
-
Fabian, C.J.1
Kimler, B.F.2
-
22
-
-
52649098048
-
Estrogen receptor-negative breast cancer is less likely to arise among lipophilic statin users
-
Kumar, A. S.; Benz, C. C.; Shim, V.; Minami, C. A.; Moore, D. H.; Esserman, L. J. Estrogen receptor-negative breast cancer is less likely to arise among lipophilic statin users Cancer Epidemiol. Biomarkers Prev. 2008, 17, 1028-1033
-
(2008)
Cancer Epidemiol. Biomarkers Prev.
, vol.17
, pp. 1028-1033
-
-
Kumar, A.S.1
Benz, C.C.2
Shim, V.3
Minami, C.A.4
Moore, D.H.5
Esserman, L.J.6
-
23
-
-
34248659399
-
Carbonic anhydrases as targets for medicinal chemistry
-
DOI 10.1016/j.bmc.2007.04.020, PII S0968089607003379
-
Supuran, C. T.; Scozzafava, A. Carbonic anhydrases as targets for medicinal chemistry Bioorg. Med. Chem. 2007, 15, 4336-4350 (Pubitemid 46777288)
-
(2007)
Bioorganic and Medicinal Chemistry
, vol.15
, Issue.13
, pp. 4336-4350
-
-
Supuran, C.T.1
Scozzafava, A.2
-
24
-
-
0035992374
-
The expression of carbonic anhydrase II in hematological malignancies
-
Leppilampi, M.; Koistinen, P.; Savolainen, E. R.; Hannuksela, J.; Parkkila, A. K.; Niemela, O.; Pastorekova, S.; Pastorek, J.; Waheed, A.; Sly, W. S.; Parkkila, S.; Rajaniemi, H. The expression of carbonic anhydrase II in hematological malignancies Clin. Cancer Res. 2002, 8, 2240-2245 (Pubitemid 34753596)
-
(2002)
Clinical Cancer Research
, vol.8
, Issue.7
, pp. 2240-2245
-
-
Leppilampi, M.1
Koistinen, P.2
Savolainen, E.-R.3
Hannuksela, J.4
Parkkila, A.-K.5
Niemela, O.6
Pastorekova, S.7
Pastorek, J.8
Waheed, A.9
Sly, W.S.10
Parkkila, S.11
Rajaniemi, H.12
-
25
-
-
0027360473
-
Role of isoprenylation in intracellular pH regulation of granulocytes
-
DOI 10.1016/0014-5793(93)80642-8
-
Arellano, R.; Grinstein, S. Role of isoprenylation in intracellular pH regulation of granulocytes FEBS Lett. 1993, 332, 247-250 (Pubitemid 23305333)
-
(1993)
FEBS Letters
, vol.332
, Issue.3
, pp. 247-250
-
-
Arellano, R.1
Grinstein, S.2
-
26
-
-
0037184125
-
Carbonic anhydrase II binds to and enhances activity of the Na+/H+ exchanger
-
Li, X. J.; Alvarez, B.; Casey, J. R.; Reithmeier, R. A. F.; Fliegel, L. Carbonic anhydrase II binds to and enhances activity of the Na+/H+ exchanger J. Biol. Chem. 2002, 277, 36085-36091
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 36085-36091
-
-
Li, X.J.1
Alvarez, B.2
Casey, J.R.3
Reithmeier, R.A.F.4
Fliegel, L.5
-
27
-
-
36849011948
-
-/- mice
-
DOI 10.1074/jbc.M707266200
-
Gonzalez-Begne, M.; Nakamoto, T.; Nguyen, H. V.; Stewart, A. K.; Alper, S. L.; Melvin, J. E. Enhanced formation of a HCO3- transport metabolon in exocrine cells of Nhe1(-/-) mice J. Biol. Chem. 2007, 282, 35125-35132 (Pubitemid 350232456)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.48
, pp. 35125-35132
-
-
Gonzalez-Begne, M.1
Nakamoto, T.2
Nguyen, H.-V.3
Stewart, A.K.4
Alper, S.L.5
Melvin, J.E.6
-
28
-
-
0034762423
-
Estrogen regulation of ion transporter messenger RNA levels in mouse efferent ductules are mediated differentially through estrogen receptor (ER) and ER
-
Lee, K. H.; Finnigan-Bunick, C.; Bahr, J.; Bunick, D. Estrogen regulation of ion transporter messenger RNA levels in mouse efferent ductules are mediated differentially through estrogen receptor (ER) alpha and ER beta Biol. Reprod. 2001, 65, 1534-1541 (Pubitemid 33031513)
-
(2001)
Biology of Reproduction
, vol.65
, Issue.5
, pp. 1534-1541
-
-
Lee, K.-H.1
Finnigan-Bunick, C.2
Bahr, J.3
Bunick, D.4
-
29
-
-
33845953699
-
2-Substituted estradiol bis-sulfamates, multitargeted antitumor agents: Synthesis, in vitro SAR, protein crystallography, and in vivo activity
-
DOI 10.1021/jm060705x
-
Leese, M. P.; Leblond, B.; Smith, A.; Newman, S. P.; Di Fiore, A.; De Simone, G.; Supuran, C. T.; Purohit, A.; Reed, M. J.; Potter, B. V. L. 2-Substituted estradiol bis-sulfamates, multitargeted antitumor agents: synthesis, in vitro SAR, protein crystallography, and in vivo activity J. Med. Chem. 2006, 49, 7683-7696 (Pubitemid 46033660)
-
(2006)
Journal of Medicinal Chemistry
, vol.49
, Issue.26
, pp. 7683-7696
-
-
Leese, M.P.1
Leblond, B.2
Smith, A.3
Newman, S.P.4
Di Fiore, A.5
De Simone, G.6
Supuran, C.T.7
Purohit, A.8
Reed, M.J.9
Potter, B.V.L.10
-
30
-
-
73649140983
-
Quantitative Phosphoproteomic Analysis of the STAT3/IL-6/HIF1 alpha Signaling Network: An Initial Study in GSC11 Glioblastoma Stem Cells
-
Nilsson, C. L.; Dillon, R.; Devakumar, A.; Shi, S. D. H.; Greig, M.; Rogers, J. C.; Krastins, B.; Rosenblatt, M.; Kilmer, G.; Major, M.; Kaboord, B. J.; Sarracino, D.; Rezai, T.; Prakash, A.; Lopez, M.; Ji, Y. J.; Priebe, W.; Lang, F. F.; Colman, H.; Conrad, C. A. Quantitative Phosphoproteomic Analysis of the STAT3/IL-6/HIF1 alpha Signaling Network: An Initial Study in GSC11 Glioblastoma Stem Cells J. Proteome Res. 2010, 9, 430-443
-
(2010)
J. Proteome Res.
, vol.9
, pp. 430-443
-
-
Nilsson, C.L.1
Dillon, R.2
Devakumar, A.3
Shi, S.D.H.4
Greig, M.5
Rogers, J.C.6
Krastins, B.7
Rosenblatt, M.8
Kilmer, G.9
Major, M.10
Kaboord, B.J.11
Sarracino, D.12
Rezai, T.13
Prakash, A.14
Lopez, M.15
Ji, Y.J.16
Priebe, W.17
Lang, F.F.18
Colman, H.19
Conrad, C.A.20
more..
-
31
-
-
0025269838
-
Metabolic basis for differential glutamine requirements of human leukemia cell lines
-
Kitoh, T.; Kubota, M.; Takimoto, T.; Hashimoto, H.; Shimizu, T.; Sano, H.; Akiyama, Y.; Mikawa, H. Metabolic basis for differential glutamine requirements of human leukemia cell lines J. Cell. Physiol. 1990, 143, 150-153
-
(1990)
J. Cell. Physiol.
, vol.143
, pp. 150-153
-
-
Kitoh, T.1
Kubota, M.2
Takimoto, T.3
Hashimoto, H.4
Shimizu, T.5
Sano, H.6
Akiyama, Y.7
Mikawa, H.8
-
32
-
-
33746655717
-
Cholesterol deficiency perturbs actin signaling and glutamate homeostasis in hippocampal astrocytes
-
Tsai, H. I.; Tsai, L. H.; Chen, M. Y.; Chou, Y. C. Cholesterol deficiency perturbs actin signaling and glutamate homeostasis in hippocampal astrocytes Brain Res. 2006, 1104, 27-38
-
(2006)
Brain Res.
, vol.1104
, pp. 27-38
-
-
Tsai, H.I.1
Tsai, L.H.2
Chen, M.Y.3
Chou, Y.C.4
-
33
-
-
0032764065
-
Protection of acute myeloblastic leukemia cells against apoptotic cell death by high glutathione and gamma-glutamylcysteine synthetase levels during etoposide-induced oxidative stress
-
Siitonen, T.; Alaruikka, P.; Mantymaa, P.; Savolainen, E. R.; Kavanagh, T. J.; Krejsa, C. M.; Franklin, C. C.; Kinnula, V.; Koistinen, P. Protection of acute myeloblastic leukemia cells against apoptotic cell death by high glutathione and gamma-glutamylcysteine synthetase levels during etoposide-induced oxidative stress Ann. Oncol. 1999, 10, 1361-1367
-
(1999)
Ann. Oncol.
, vol.10
, pp. 1361-1367
-
-
Siitonen, T.1
Alaruikka, P.2
Mantymaa, P.3
Savolainen, E.R.4
Kavanagh, T.J.5
Krejsa, C.M.6
Franklin, C.C.7
Kinnula, V.8
Koistinen, P.9
-
34
-
-
0036083396
-
The ubiquitin-proteasome proteolytic pathway: Destruction for the sake of construction
-
Glickman, M. H.; Ciechanover, A. The ubiquitin-proteasome proteolytic pathway: Destruction for the sake of construction Physiol. Rev. 2002, 82, 373-428 (Pubitemid 34654457)
-
(2002)
Physiological Reviews
, vol.82
, Issue.2
, pp. 373-428
-
-
Glickman, M.H.1
Ciechanover, A.2
|