Protection of acute myeloblastic leukemia cells against apoptotic cell death by high glutathione and gamma-glutamylcysteine synthetase levels during etoposide-induced oxidative stress

Annals of Oncology

Volumn 10, Issue 11, 1999, Pages 1361-1367

  Siitonen, T ^a   Alaruikka, P ^a   Mantymaa P ^a   Savolainen, E R ^a   Kavanagh, T J ^b   Krejsa, C M ^b   Franklin, C C ^b   Kinnula, V ^a   Koistinen, P ^a  

^a UNIVERSITY OF OULU   (Finland)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

GCS; AML; Apoptosis; Etoposide; Glutathione; Oxidative stress

Indexed keywords

ETOPOSIDE; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE;

ACUTE MYELOBLASTIC LEUKEMIA; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL LEVEL; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG MECHANISM; ENZYME ASSAY; ENZYME SUBUNIT; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BLOTTING, WESTERN; DRUG RESISTANCE, NEOPLASM; ETOPOSIDE; FLOW CYTOMETRY; GLUTAMATE-CYSTEINE LIGASE; HUMANS; LEUKEMIA, MYELOCYTIC, ACUTE; OXIDATIVE STRESS; SENSITIVITY AND SPECIFICITY; TUMOR CELLS, CULTURED;

EID: 0032764065     PISSN: 09237534     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1008382912096     Document Type: Article

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