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Volumn 301, Issue 6, 2011, Pages 1625-1634

Stimulation of the hypothalamic ventromedial nuclei by pituitary adenylate cyclase-activating polypeptide induces hypophagia and thermogenesis

Author keywords

Energy expenditure; Feeding; Pro opiomelanocortin; Rat

Indexed keywords

ADENYLATE CYCLASE; MESSENGER RNA; POLYPEPTIDE; PROOPIOMELANOCORTIN;

EID: 82755192274     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00334.2011     Document Type: Article
Times cited : (57)

References (64)
  • 2
    • 0025267399 scopus 로고
    • Intra-ventromedial hypothalamic injection of glutamate stimulates brown adipose tissue thermogenesis in the rat
    • Amir S. Intra-ventromedial hypothalamic injection of glutamate stimulates brown adipose tissue thermogenesis in the rat. Brain Res 511: 341-344, 1990.
    • (1990) Brain Res , vol.511 , pp. 341-344
    • Amir, S.1
  • 3
    • 0001643038 scopus 로고
    • Activity of single neurons in the hypothalamic feeding centers: Effect of glucose
    • Anand BK, Chhina GS, Sharma KN, Dua S, Singh B. Activity of single neurons in the hypothalamic feeding centers: effect of glucose. Am J Physiol 207: 1146-1154, 1964.
    • (1964) Am J Physiol , vol.207 , pp. 1146-1154
    • Anand, B.K.1    Chhina, G.S.2    Sharma, K.N.3    Dua, S.4    Singh, B.5
  • 4
    • 0028133318 scopus 로고
    • Organization of projections from the ventromedial nucleus of the hypothalamus: A Phaseolus vulgarisleucoagglutinin study in the rat
    • Canteras NS, Simerly RB, Swanson LW. Organization of projections from the ventromedial nucleus of the hypothalamus: a Phaseolus vulgarisleucoagglutinin study in the rat. J Comp Neurol 348: 41-79, 1994.
    • (1994) J Comp Neurol , vol.348 , pp. 41-79
    • Canteras, N.S.1    Simerly, R.B.2    Swanson, L.W.3
  • 5
    • 0029050541 scopus 로고
    • Locomotor activity and utilization of energy reserves during fasting after ventromedial hypothalamic lesions
    • Challet E, Le Maho Y, Malan A. Locomotor activity and utilization of energy reserves during fasting after ventromedial hypothalamic lesions. Physiol Behav 58: 257-264, 1995.
    • (1995) Physiol Behav , vol.58 , pp. 257-264
    • Challet, E.1    Le Maho, Y.2    Malan, A.3
  • 6
    • 0029948089 scopus 로고    scopus 로고
    • Ventromedial hypothalamic lesions prevent the fasting-induced changes in day-night pattern of locomotor activity
    • Challet E, Le Maho Y, Pevet P, Nobelis P, Malan A. Ventromedial hypothalamic lesions prevent the fasting-induced changes in day-night pattern of locomotor activity. Behav Brain Res 77: 155-163, 1996.
    • (1996) Behav Brain Res , vol.77 , pp. 155-163
    • Challet, E.1    Le Maho, Y.2    Pevet, P.3    Nobelis, P.4    Malan, A.5
  • 7
    • 0028867338 scopus 로고
    • Anorectic and neurochemical effects of pituitary adenylate cyclase activating polypeptide in rats
    • Chance WT, Thompson H, Thomas I, Fischer JE. Anorectic and neurochemical effects of pituitary adenylate cyclase activating polypeptide in rats. Peptides 16: 1511-1516, 1995.
    • (1995) Peptides , vol.16 , pp. 1511-1516
    • Chance, W.T.1    Thompson, H.2    Thomas, I.3    Fischer, J.E.4
  • 8
    • 77749310482 scopus 로고    scopus 로고
    • Suppresses anorexigenic output from the ventromedial nucleus of the hypothalamus
    • Chee MJ, Myers MG Jr, Price CJ, Colmers WF. Neuropeptide Y suppresses anorexigenic output from the ventromedial nucleus of the hypothalamus. J Neurosci 30: 3380-3390, 2010.
    • (2010) J Neurosci , vol.30 , pp. 3380-3390
    • Chee, M.J.1    Myers Jr., M.G.2    Price, C.J.3    Colmers, W.F.4    Neuropeptide, Y.5
  • 9
    • 0033304973 scopus 로고    scopus 로고
    • Hypothalamic obesity: Multiple routes mediated by loss of function in medial cell groups
    • Choi S, Dallman MF. Hypothalamic obesity: multiple routes mediated by loss of function in medial cell groups. Endocrinology 140: 4081-4088, 1999.
    • (1999) Endocrinology , vol.140 , pp. 4081-4088
    • Choi, S.1    Dallman, M.F.2
  • 10
    • 0029828331 scopus 로고    scopus 로고
    • The hypothalamic ventromedial nuclei couple activity in the hypothalamo-pituitary-adrenal axis to the morning fed or fasted state
    • Choi S, Horsley C, Aguila S, Dallman MF. The hypothalamic ventromedial nuclei couple activity in the hypothalamo-pituitary-adrenal axis to the morning fed or fasted state. J Neurosci 16: 8170-8180, 1996.
    • (1996) J Neurosci , vol.16 , pp. 8170-8180
    • Choi, S.1    Horsley, C.2    Aguila, S.3    Dallman, M.F.4
  • 11
    • 0344701101 scopus 로고    scopus 로고
    • Hypothalamic ventromedial nuclei amplify circadian rhythms: Do they contain a food-entrained endogenous oscillator?
    • Choi S, Wong LS, Yamat C, Dallman MF. Hypothalamic ventromedial nuclei amplify circadian rhythms: do they contain a food-entrained endogenous oscillator? J Neurosci 18: 3843-3852, 1998.
    • (1998) J Neurosci , vol.18 , pp. 3843-3852
    • Choi, S.1    Wong, L.S.2    Yamat, C.3    Dallman, M.F.4
  • 12
    • 58149477334 scopus 로고    scopus 로고
    • Modulation of AMPA receptor-mediated ion current by pituitary adenylate cyclase-activating polypeptide (PACAP) in CA1 pyramidal neurons from rat hippocampus
    • Costa L, Santangelo F, Li Volsi G, Ciranna L. Modulation of AMPA receptor-mediated ion current by pituitary adenylate cyclase-activating polypeptide (PACAP) in CA1 pyramidal neurons from rat hippocampus. Hippocampus 19: 99-109, 2009.
    • (2009) Hippocampus , vol.19 , pp. 99-109
    • Costa, L.1    Santangelo, F.2    Li Volsi, G.3    Ciranna, L.4
  • 13
    • 66149083518 scopus 로고    scopus 로고
    • Insulin blunts the response of glucose-excited neurons in the ventrolateral-ventromedial hypothalamic nucleus to decreased glucose
    • Cotero VE, Routh VH. Insulin blunts the response of glucose-excited neurons in the ventrolateral-ventromedial hypothalamic nucleus to decreased glucose. Am J Physiol Endocrinol Metab 296: E1101-E1109, 2009.
    • (2009) Am J Physiol Endocrinol Metab , vol.296
    • Cotero, V.E.1    Routh, V.H.2
  • 14
    • 33846034012 scopus 로고    scopus 로고
    • Hypothalamic and brainstem sources of pituitary adenylate cyclase-activating polypeptide nerve fibers innervating the hypothalamic paraventricular nucleus in the rat
    • Das M, Vihlen CS, Legradi G. Hypothalamic and brainstem sources of pituitary adenylate cyclase-activating polypeptide nerve fibers innervating the hypothalamic paraventricular nucleus in the rat. J Comp Neurol 500: 761-776, 2007.
    • (2007) J Comp Neurol , vol.500 , pp. 761-776
    • Das, M.1    Vihlen, C.S.2    Legradi, G.3
  • 15
    • 0017771170 scopus 로고
    • Cholecystokinin produces bait shyness in rats
    • Deutsch JA, Hardy WT. Cholecystokinin produces bait shyness in rats. Nature 266: 196, 1977.
    • (1977) Nature , vol.266 , pp. 196
    • Deutsch, J.A.1    Hardy, W.T.2
  • 17
    • 60849086453 scopus 로고    scopus 로고
    • VPAC and PAC receptors: From ligands to function
    • Dickson L, Finlayson K. VPAC and PAC receptors: from ligands to function. Pharmacol Ther 121: 294-316, 2009.
    • (2009) Pharmacol Ther , vol.121 , pp. 294-316
    • Dickson, L.1    Finlayson, K.2
  • 18
    • 45849130547 scopus 로고    scopus 로고
    • Agouti-related peptide and MC3/4 receptor agonists both inhibit excitatory hypothalamic ventromedial nucleus neurons
    • Fu LY, van den Pol AN. Agouti-related peptide and MC3/4 receptor agonists both inhibit excitatory hypothalamic ventromedial nucleus neurons. J Neurosci 28: 5433-5449, 2008.
    • (2008) J Neurosci , vol.28 , pp. 5433-5449
    • Fu, L.Y.1    van den Pol, A.N.2
  • 20
    • 0034791010 scopus 로고    scopus 로고
    • Targeted disruption of the pituitary adenylate cyclase-activating polypeptide gene results in early postnatal death associated with dysfunction of lipid and carbohydrate metabolism
    • Gray SL, Cummings KJ, Jirik FR, Sherwood NM. Targeted disruption of the pituitary adenylate cyclase-activating polypeptide gene results in early postnatal death associated with dysfunction of lipid and carbohydrate metabolism. Mol Endocrinol 15: 1739-1747, 2001.
    • (2001) Mol Endocrinol , vol.15 , pp. 1739-1747
    • Gray, S.L.1    Cummings, K.J.2    Jirik, F.R.3    Sherwood, N.M.4
  • 21
    • 0036773485 scopus 로고    scopus 로고
    • Temperaturesensitive phenotype in mice lacking pituitary adenylate cyclase-activating polypeptide
    • Gray SL, Yamaguchi N, Vencova P, Sherwood NM. Temperaturesensitive phenotype in mice lacking pituitary adenylate cyclase-activating polypeptide. Endocrinology 143: 3946-3954, 2002.
    • (2002) Endocrinology , vol.143 , pp. 3946-3954
    • Gray, S.L.1    Yamaguchi, N.2    Vencova, P.3    Sherwood, N.M.4
  • 22
    • 0030726726 scopus 로고    scopus 로고
    • Effects of pituitary adenylate cyclase-activating polypeptide (PACAP) on corticotropin-releasing hormone (CRH) gene expression in the rat hypothalamic paraventricular nucleus
    • Grinevich V, Fournier A, Pelletier G. Effects of pituitary adenylate cyclase-activating polypeptide (PACAP) on corticotropin-releasing hormone (CRH) gene expression in the rat hypothalamic paraventricular nucleus. Brain Res 773: 190-196, 1997.
    • (1997) Brain Res , vol.773 , pp. 190-196
    • Grinevich, V.1    Fournier, A.2    Pelletier, G.3
  • 23
    • 0037175342 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating peptide in the rat central nervous system: An immunohistochemical and in situ hybridization study
    • Hannibal J. Pituitary adenylate cyclase-activating peptide in the rat central nervous system: an immunohistochemical and in situ hybridization study. J Comp Neurol 453: 389-417, 2002.
    • (2002) J Comp Neurol , vol.453 , pp. 389-417
    • Hannibal, J.1
  • 24
    • 0028888345 scopus 로고
    • Gene expression of pituitary adenylate cyclase activating polypeptide (PACAP) in the rat hypothalamus
    • Hannibal J, Mikkelsen JD, Clausen H, Holst JJ, Wulff BS, Fahrenkrug J. Gene expression of pituitary adenylate cyclase activating polypeptide (PACAP) in the rat hypothalamus. Regul Pept 55: 133-148, 1995.
    • (1995) Regul Pept , vol.55 , pp. 133-148
    • Hannibal, J.1    Mikkelsen, J.D.2    Clausen, H.3    Holst, J.J.4    Wulff, B.S.5    Fahrenkrug, J.6
  • 25
    • 0023090846 scopus 로고
    • Localization of preproenkephalin mRNA in the rat brain and spinal cord by in situ hybridization
    • Harlan RE, Shivers BD, Romano GJ, Howells RD, Pfaff DW. Localization of preproenkephalin mRNA in the rat brain and spinal cord by in situ hybridization. J Comp Neurol 258: 159-184, 1987.
    • (1987) J Comp Neurol , vol.258 , pp. 159-184
    • Harlan, R.E.1    Shivers, B.D.2    Romano, G.J.3    Howells, R.D.4    Pfaff, D.W.5
  • 26
    • 9444281442 scopus 로고    scopus 로고
    • Distribution of the mRNA for a pituitary adenylate cyclase-activating polypeptide receptor in the rat brain: An in situ hybridization study
    • Hashimoto H, Nogi H, Mori K, Ohishi H, Shigemoto R, Yamamoto K, Matsuda T, Mizuno N, Nagata S, Baba A. Distribution of the mRNA for a pituitary adenylate cyclase-activating polypeptide receptor in the rat brain: an in situ hybridization study. J Comp Neurol 371: 567-577, 1996.
    • (1996) J Comp Neurol , vol.371 , pp. 567-577
    • Hashimoto, H.1    Nogi, H.2    Mori, K.3    Ohishi, H.4    Shigemoto, R.5    Yamamoto, K.6    Matsuda, T.7    Mizuno, N.8    Nagata, S.9    Baba, A.10
  • 27
    • 72449209171 scopus 로고    scopus 로고
    • PACAP neurons in the hypothalamic ventromedial nucleus are targets of central leptin signaling
    • Hawke Z, Ivanov TR, Bechtold DA, Dhillon H, Lowell BB, Luckman SM. PACAP neurons in the hypothalamic ventromedial nucleus are targets of central leptin signaling. J Neurosci 29: 14828-14835, 2009.
    • (2009) J Neurosci , vol.29 , pp. 14828-14835
    • Hawke, Z.1    Ivanov, T.R.2    Bechtold, D.A.3    Dhillon, H.4    Lowell, B.B.5    Luckman, S.M.6
  • 28
    • 0002566890 scopus 로고
    • Brown adipose tissue thermogenesis: Role in thermoregulation energy regulation, and obesity
    • edited by Schonbaum E and Lomax P. New York: Pergamon
    • Himms-Hagen J. Brown adipose tissue thermogenesis: role in thermoregulation energy regulation, and obesity. In: Thermoregulation: Physiology and Biochemistry, edited by Schonbaum E and Lomax P. New York: Pergamon, 1990, p. 327-414.
    • (1990) Thermoregulation: Physiology and Biochemistry , pp. 327-414
    • Himms-Hagen, J.1
  • 29
    • 0022500132 scopus 로고
    • Enkephalin-like immunoreactive neurons and fibers in the ventromedial hypothalamic nucleus
    • Inagaki S, Kubota Y, Kito S, Yamano M, Tohyama M. Enkephalin-like immunoreactive neurons and fibers in the ventromedial hypothalamic nucleus. Brain Res Bull 17: 159-167, 1986.
    • (1986) Brain Res Bull , vol.17 , pp. 159-167
    • Inagaki, S.1    Kubota, Y.2    Kito, S.3    Yamano, M.4    Tohyama, M.5
  • 30
    • 33751170897 scopus 로고    scopus 로고
    • Amygdaloid lesion-induced obesity: Relation to sexual behavior, olfaction, and the ventromedial hypothalamus
    • King BM. Amygdaloid lesion-induced obesity: relation to sexual behavior, olfaction, and the ventromedial hypothalamus. Am J Physiol Regul Integr Comp Physiol 291: R1201-R1214, 2006.
    • (2006) Am J Physiol Regul Integr Comp Physiol , vol.291
    • King, B.M.1
  • 31
    • 31944452253 scopus 로고    scopus 로고
    • The rise, fall, and resurrection of the ventromedial hypothalamus in the regulation of feeding behavior and body weight
    • King BM. The rise, fall, and resurrection of the ventromedial hypothalamus in the regulation of feeding behavior and body weight. Physiol Behav 87: 221-244, 2006.
    • (2006) Physiol Behav , vol.87 , pp. 221-244
    • King, B.M.1
  • 32
    • 79851516881 scopus 로고    scopus 로고
    • Location of glutamatergic/aspartatergic neurons projecting to the hypothalamic ventromedial nucleus studied by autoradiography of retrogradely transported [3H]D-aspartate
    • Kiss J, Csaki A, Halasz B. Location of glutamatergic/aspartatergic neurons projecting to the hypothalamic ventromedial nucleus studied by autoradiography of retrogradely transported [3H]D-aspartate. Neuroscience 176: 210-224, 2011.
    • (2011) Neuroscience , vol.176 , pp. 210-224
    • Kiss, J.1    Csaki, A.2    Halasz, B.3
  • 34
    • 0032502579 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide-nerve terminals densely innervate corticotropin-releasing hormone-neurons in the hypothalamic paraventricular nucleus of the rat
    • Legradi G, Hannibal J, Lechan RM. Pituitary adenylate cyclase-activating polypeptide-nerve terminals densely innervate corticotropin-releasing hormone-neurons in the hypothalamic paraventricular nucleus of the rat. Neurosci Lett 246: 145-148, 1998.
    • (1998) Neurosci Lett , vol.246 , pp. 145-148
    • Legradi, G.1    Hannibal, J.2    Lechan, R.M.3
  • 36
    • 0031668175 scopus 로고    scopus 로고
    • Aging and fasting regulation of leptin and hypothalamic neuropeptide Y gene expression
    • Li H, Matheny M, Tumer N, Scarpace PJ. Aging and fasting regulation of leptin and hypothalamic neuropeptide Y gene expression. Am J Physiol Endocrinol Metab 275: E405-E411, 1998.
    • (1998) Am J Physiol Endocrinol Metab , vol.275
    • Li, H.1    Matheny, M.2    Tumer, N.3    Scarpace, P.J.4
  • 37
    • 30544436124 scopus 로고    scopus 로고
    • Modulation of NMDA receptors by pituitary adenylate cyclase activating peptide in CA1 neurons requires G q, protein kinase C, and activation of Src
    • Macdonald DS, Weerapura M, Beazely MA, Martin L, Czerwinski W, Roder JC, Orser BA, MacDonald JF. Modulation of NMDA receptors by pituitary adenylate cyclase activating peptide in CA1 neurons requires G q, protein kinase C, and activation of Src. J Neurosci 25: 11374-11384, 2005.
    • (2005) J Neurosci , vol.25 , pp. 11374-11384
    • Macdonald, D.S.1    Weerapura, M.2    Beazely, M.A.3    Martin, L.4    Czerwinski, W.5    Roder, J.C.6    Orser, B.A.7    Macdonald, J.F.8
  • 38
    • 0027055174 scopus 로고
    • Pituitary adenylate cyclase activating polypeptide (PACAP) reduces food intake in mice
    • Morley JE, Horowitz M, Morley PM, Flood JF. Pituitary adenylate cyclase activating polypeptide (PACAP) reduces food intake in mice. Peptides 13: 1133-1135, 1992.
    • (1992) Peptides , vol.13 , pp. 1133-1135
    • Morley, J.E.1    Horowitz, M.2    Morley, P.M.3    Flood, J.F.4
  • 40
    • 33751042201 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide directly modulates the activity of proopiomelanocortin neurons in the rat arcuate nucleus
    • Mounien L, Bizet P, Boutelet I, Gourcerol G, Fournier A, Vaudry H, Jegou S. Pituitary adenylate cyclase-activating polypeptide directly modulates the activity of proopiomelanocortin neurons in the rat arcuate nucleus. Neuroscience 143: 155-163, 2006.
    • (2006) Neuroscience , vol.143 , pp. 155-163
    • Mounien, L.1    Bizet, P.2    Boutelet, I.3    Gourcerol, G.4    Fournier, A.5    Vaudry, H.6    Jegou, S.7
  • 42
    • 5644221631 scopus 로고    scopus 로고
    • PACAP deficient mice display reduced carbohydrate intake and PACAP activates NPY-containing neurons in the rat hypothalamic arcuate nucleus
    • Nakata M, Kohno D, Shintani N, Nemoto Y, Hashimoto H, Baba A, Yada T. PACAP deficient mice display reduced carbohydrate intake and PACAP activates NPY-containing neurons in the rat hypothalamic arcuate nucleus. Neurosci Lett 370: 252-256, 2004.
    • (2004) Neurosci Lett , vol.370 , pp. 252-256
    • Nakata, M.1    Kohno, D.2    Shintani, N.3    Nemoto, Y.4    Hashimoto, H.5    Baba, A.6    Yada, T.7
  • 43
    • 0027537148 scopus 로고
    • Interaction between excitatory and inhibitory amino acids in the ventromedial nucleus of the hypothalamus in inducing hyper-running
    • Narita K, Yokawa T, Nishihara M, Takahashi M. Interaction between excitatory and inhibitory amino acids in the ventromedial nucleus of the hypothalamus in inducing hyper-running. Brain Res 603: 243-247, 1993.
    • (1993) Brain Res , vol.603 , pp. 243-247
    • Narita, K.1    Yokawa, T.2    Nishihara, M.3    Takahashi, M.4
  • 44
    • 0024458117 scopus 로고
    • Intrinsic synapses in the ventromedial nucleus of the hypothalamus: An ultrastructural study
    • Nishizuka M, Pfaff DW. Intrinsic synapses in the ventromedial nucleus of the hypothalamus: an ultrastructural study. J Comp Neurol 286: 260-268, 1989.
    • (1989) J Comp Neurol , vol.286 , pp. 260-268
    • Nishizuka, M.1    Pfaff, D.W.2
  • 45
    • 0034097510 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide induces hyperthermia in the rat
    • Pataki I, Adamik A, Jaszberenyi M, Macsai M, Telegdy G. Pituitary adenylate cyclase-activating polypeptide induces hyperthermia in the rat. Neuropharmacology 39: 1303-1308, 2000.
    • (2000) Neuropharmacology , vol.39 , pp. 1303-1308
    • Pataki, I.1    Adamik, A.2    Jaszberenyi, M.3    Macsai, M.4    Telegdy, G.5
  • 47
    • 0019491322 scopus 로고
    • Activation of brown adipose tissue thermogenesis by the ventromedial hypothalamus
    • Perkins MN, Rothwell NJ, Stock MJ, Stone TW. Activation of brown adipose tissue thermogenesis by the ventromedial hypothalamus. Nature 289: 401-402, 1981.
    • (1981) Nature , vol.289 , pp. 401-402
    • Perkins, M.N.1    Rothwell, N.J.2    Stock, M.J.3    Stone, T.W.4
  • 48
    • 35148838131 scopus 로고    scopus 로고
    • Experimental dissociation of neural circuits underlying conditioned avoidance and hypophagic responses to lithium chloride
    • Rinaman L, Dzmura V. Experimental dissociation of neural circuits underlying conditioned avoidance and hypophagic responses to lithium chloride. Am J Physiol Regul Integr Comp Physiol 293: R1495-R1503, 2007.
    • (2007) Am J Physiol Regul Integr Comp Physiol , vol.293
    • Rinaman, L.1    Dzmura, V.2
  • 49
    • 0023213629 scopus 로고
    • The effect of intrahypothalamic injections of glucose on sympathetic efferent firing rate
    • Sakaguchi T, Bray GA. The effect of intrahypothalamic injections of glucose on sympathetic efferent firing rate. Brain Res Bull 18: 591-595, 1987.
    • (1987) Brain Res Bull , vol.18 , pp. 591-595
    • Sakaguchi, T.1    Bray, G.A.2
  • 50
    • 27744457512 scopus 로고    scopus 로고
    • Topographic mapping of VMH→arcuate nucleus microcircuits and their reorganization by fasting
    • Sternson SM, Shepherd GM, Friedman JM. Topographic mapping of VMH→arcuate nucleus microcircuits and their reorganization by fasting. Nat Neurosci 8: 1356-1363, 2005.
    • (2005) Nat Neurosci , vol.8 , pp. 1356-1363
    • Sternson, S.M.1    Shepherd, G.M.2    Friedman, J.M.3
  • 51
    • 0025942149 scopus 로고
    • Ventromedial hypothalamic stimulation enhances peripheral glucose uptake in anesthetized rats
    • Sudo M, Minokoshi Y, Shimazu T. Ventromedial hypothalamic stimulation enhances peripheral glucose uptake in anesthetized rats. Am J Physiol Endocrinol Metab 261: E298-E303, 1991.
    • (1991) Am J Physiol Endocrinol Metab , vol.261
    • Sudo, M.1    Minokoshi, Y.2    Shimazu, T.3
  • 53
    • 79955465971 scopus 로고    scopus 로고
    • The melanocortin system is involved in regulating autonomic nerve activity through central pituitary adenylate cyclase-activating polypeptide
    • Tanida M, Shintani N, Hashimoto H. The melanocortin system is involved in regulating autonomic nerve activity through central pituitary adenylate cyclase-activating polypeptide. Neurosci Res 70: 55-61, 2011.
    • (2011) Neurosci Res , vol.70 , pp. 55-61
    • Tanida, M.1    Shintani, N.2    Hashimoto, H.3
  • 57
    • 34347207562 scopus 로고    scopus 로고
    • Differential intracellular signaling through PAC1 isoforms as a result of alternative splicing in the first extracellular domain and the third intracellular loop
    • Ushiyama M, Ikeda R, Sugawara H, Yoshida M, Mori K, Kangawa K, Inoue K, Yamada K, Miyata A. Differential intracellular signaling through PAC1 isoforms as a result of alternative splicing in the first extracellular domain and the third intracellular loop. Mol Pharmacol 72: 103-111, 2007.
    • (2007) Mol Pharmacol , vol.72 , pp. 103-111
    • Ushiyama, M.1    Ikeda, R.2    Sugawara, H.3    Yoshida, M.4    Mori, K.5    Kangawa, K.6    Inoue, K.7    Yamada, K.8    Miyata, A.9
  • 59
    • 0032577376 scopus 로고    scopus 로고
    • Signals that regulate food intake and energy homeostasis
    • Woods SC, Seeley RJ, Porte D Jr, Schwartz MW. Signals that regulate food intake and energy homeostasis. Science 280: 1378-1383, 1998.
    • (1998) Science , vol.280 , pp. 1378-1383
    • Woods, S.C.1    Seeley, R.J.2    Porte Jr., D.3    Schwartz, M.W.4
  • 60
    • 0037646486 scopus 로고    scopus 로고
    • Pituitary adenylate cyclaseactivating polypeptide (PACAP1-38) enhances N-methyl-D-aspartate receptor function and brain-derived neurotrophic factor expression via RACK1
    • Yaka R, He DY, Phamluong K, Ron D. Pituitary adenylate cyclaseactivating polypeptide (PACAP1-38) enhances N-methyl-D-aspartate receptor function and brain-derived neurotrophic factor expression via RACK1. J Biol Chem 278: 9630-9638, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 9630-9638
    • Yaka, R.1    He, D.Y.2    Phamluong, K.3    Ron, D.4
  • 62
    • 77955417166 scopus 로고    scopus 로고
    • Pro-opiomelanocortin gene transfer to the nucleus of the solitary track but not arcuate nucleus ameliorates chronic diet-induced obesity
    • Zhang Y, Rodrigues E, Gao YX, King M, Cheng KY, Erdos B, Tumer N, Carter C, Scarpace PJ. Pro-opiomelanocortin gene transfer to the nucleus of the solitary track but not arcuate nucleus ameliorates chronic diet-induced obesity. Neuroscience 169: 1662-1671, 2010.
    • (2010) Neuroscience , vol.169 , pp. 1662-1671
    • Zhang, Y.1    Rodrigues, E.2    Gao, Y.X.3    King, M.4    Cheng, K.Y.5    Erdos, B.6    Tumer, N.7    Carter, C.8    Scarpace, P.J.9
  • 63
    • 77957608055 scopus 로고    scopus 로고
    • The medial amygdalar nucleus: A novel glucose-sensing region that modulates the counterregulatory response to hypoglycemia
    • Zhou L, Podolsky N, Sang Z, Ding Y, Fan X, Tong Q, Levin BE, McCrimmon RJ. The medial amygdalar nucleus: a novel glucose-sensing region that modulates the counterregulatory response to hypoglycemia. Diabetes 59: 2646-2652, 2010.
    • (2010) Diabetes , vol.59 , pp. 2646-2652
    • Zhou, L.1    Podolsky, N.2    Sang, Z.3    Ding, Y.4    Fan, X.5    Tong, Q.6    Levin, B.E.7    McCrimmon, R.J.8
  • 64
    • 0036642970 scopus 로고    scopus 로고
    • Distribution of vesicular glutamate transporter mRNA in rat hypothalamus
    • Ziegler DR, Cullinan WE, Herman JP. Distribution of vesicular glutamate transporter mRNA in rat hypothalamus. J Comp Neurol 448: 217-229, 2002.
    • (2002) J Comp Neurol , vol.448 , pp. 217-229
    • Ziegler, D.R.1    Cullinan, W.E.2    Herman, J.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.