Abrogation of Cbl-PI3K interaction increases bone formation and osteoblast proliferation

Calcified Tissue International

Volumn 89, Issue 5, 2011, Pages 396-410

  Brennan, Tracy ^a   Adapala, Naga Suresh ^a,b   Barbe, Mary F ^a   Yingling, Vanessa ^a   Sanjay, Archana ^a,b  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b New England Musculoskeletal Institute   (United States)

Author keywords

Cbl; Osteoblast; PI3K; Proliferation; SDF 1

Indexed keywords

BROMSULFOPHTHALEIN; CBL PROTEIN; CHEMOKINE RECEPTOR CXCR4; COLLAGEN TYPE 1; COLLAGEN TYPE 1A; INTERLEUKIN 18; INTERLEUKIN 1BETA; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P85; RANTES; STROMAL CELL DERIVED FACTOR 1; TRANSCRIPTION FACTOR RUNX2; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE GROWTH; BONE HOMEOSTASIS; BONE MARROW CELL; BONE MASS; CANCELLOUS BONE; CELL DIFFERENTIATION; CELL FUNCTION; CELL PROLIFERATION; CONTROLLED STUDY; CORTICAL BONE; ENZYME PHOSPHORYLATION; EX VIVO STUDY; GENE EXPRESSION; GENE TARGETING; HOMEOSTASIS; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOCLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; STROMA CELL; TRABECULAR BONE; UPREGULATION; WILD TYPE;

ANIMALS; BONE AND BONES; CELL PROLIFERATION; MICE; MICE, KNOCKOUT; OSTEOBLASTS; OSTEOGENESIS; PHOSPHATIDYLINOSITOL 3-KINASE; PROTO-ONCOGENE PROTEINS C-CBL;

EID: 82755182581     PISSN: 0171967X     EISSN: 14320827     Source Type: Journal    
DOI: 10.1007/s00223-011-9531-z     Document Type: Article

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