Effects of freeze-dried cranberry powder on serum lipids and inflammatory markers in lipopolysaccharide treated rats fed an atherogenic diet

Nutrition Research and Practice

Volumn 5, Issue 5, 2011, Pages 404-411

  Kim, Mi Joung ^a   Ohn, Jeong ^a   Kim, Jung Hee ^a   Kwak, Ho Kyung ^b  

^a Seoul Women University   (South Korea)

^b Korea National Open University   (South Korea)

Author keywords

Atherogenic diet; C reactive protein (CRP); Cranberry powder; IL 1 ; IL 10

Indexed keywords

EID: 82755170313     PISSN: 19761457     EISSN: 20056168     Source Type: Journal    
DOI: 10.4162/nrp.2011.5.5.404     Document Type: Article

References (49)

1. World Health Organization [internet]. The top ten causes of death; Fact sheet No 310 [updated 2011 June]. Available from: http://www.who.int/mediacentre/factsheets/fs310/en/index.html.
2. Reed J. Cranberry flavonoids, atherosclerosis and cardiovascular health. Crit Rev Food Sci Nutr 2002;42:301-16.
3. Mahmoudi M, Curzen N, Gallagher PJ. Atherogenesis: the role of inflammation and infection. Histopathology 2007;50:535-46.
4. Baldassarre D, Porta B, Camera M, Amato M, Arquati M, Brusoni B, Fiorentini C, Montorsi P, Romano S, Veglia F, Tremoli E, Cortellaro M; MIAMI Study Group. Markers of inflammation, thrombosis and endothelial activation correlate with carotid IMT regression in stable coronary disease after atorvastatin treatment. Nutr Metab Cardiovasc Dis 2009;19: 481-90.
5. Pearson TA, Mensah GA, Alexander RW, Anderson JL, Cannon RO 3rd, Criqui M, Fadl YY, Fortmann SP, Hong Y, Myers GL, Rifai N, Smith SC Jr, Taubert K, Tracy RP, Vinicor F. Markers of inflammation and cardiovascular disease: application to clinical and public health practice: A statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association. Circulation 2003;107: 499-511.
6. Huang Y, Nikolic D, Pendland S, Doyle BJ, Locklear TD, Mahady GB. Effects of cranberry extracts and ursolic acid derivatives on P-fimbriated Escherichia coli, COX-2 activity, pro-inflammatory cytokine release and the NF-κβ transcriptional response in vitro. Pharm Biol 2009;47:18-25.
7. Cimolai N, Cimolai T. The cranberry and the urinary tract. Eur J Clin Microbiol Infect Dis 2007;26:767-76.
8. Kim MJ, Jung HN, Kim KN, Kwak HK. Effects of cranberry powder on serum lipid profiles and biomarkers of oxidative stress in rats fed an atherogenic diet. Nutr Res Pract 2008;2:158-64.
9. Sun J, Hai Liu R. Cranberry phytochemical extracts induce cell cycle arrest and apoptosis in human MCF-7 breast cancer cells. Cancer Lett 2006;241:124-34.
10. Bodet C, Grenier D, Chandad F, Ofek I, Steinberg D, Weiss EI. Potential oral health benefits of cranberry. Crit Rev Food Sci Nutr 2008;48:672-80.
11. McKay DL, Blumberg JB. Cranberries (Vaccinium macrocarpon) and cardiovascular disease risk factors. Nutr Rev 2007;65: 490-502.
12. Ruel G, Couillard C. Evidences of the cardioprotective potential of fruits: the case of cranberries. Mol Nutr Food Res 2007;51: 692-701.
13. Neto CC. Cranberry and blueberry: evidence for protective effects against cancer and vascular diseases. Mol Nutr Food Res 2007;51:652-64.
14. Vinson JA, Zubik L, Bose P, Samman N, Proch J. Dried fruits: excellent in vitro and in vivo antioxidants. J Am Coll Nutr 2005;24:44-50.
15. Westerterp M, Berbée JF, Pires NM, van Mierlo GJ, Kleemann R, Romijn JA, Havekes LM, Rensen PC. Apolipoprotein C-I is crucially involved in lipopolysaccharide-induced atherosclerosis development in apolipoprotein E-knockout mice. Circulation 2007;116:2173-81.
16. Kim SJ, Park JH, Kim KH, Lee WR, Lee S, Kwon OC, Kim KS, Park KK. Effect of NF-κB decoy oligodeoxynucleotide on LPS/high-fat diet-induced atherosclerosis in an animal model. Basic Clin Pharmacol Toxicol 2010;107:925-30.
17. Report of the American Institute of Nurtition ad hoc Committee on Standards for Nutritional Studies. J Nutr 1977;107:1340-8.
18. Ainsworth EA, Gillespie KM. Estimation of total phenolic content and other oxidation substrates in plant tissues using Folin-Ciocalteu reagent. Nat Protoc 2007;2:875-7.
19. Jia Z, Tang M, Wu J. The determination of flavonoid contents in mulberry and their scavenging effects on superoxides radicals. Food Chem 1999;64:555-9.
20. Ryu MH, Cha YS. The effects of a high-fat or high-sucrose diet on serum lipid profiles, hepatic acyl-CoA synthetase, carnitine palmitoyltransferase-I, and the acetyl-CoA carboxylase mRNA levels in rats. J Biochem Mol Biol 2003;36:312-8.
21. Uchiumi D, Kobayashi M, Tachikawa T, Hasegawa K. Subcutaneous and continuous administration of lipopolysaccharide increases serum levels of triglyceride and monocyte chemoattractant protein-1 in rats. J Periodontal Res 2004;39:120-8.
22. Ruel G, Pomerleau S, Couture P, Lemieux S, Lamarche B, Couillard C. Favourable impact of low-calorie cranberry juice consumption on plasma HDL-cholesterol concentrations in men. Br J Nutr 2006;96:357-64.
23. Kalgaonkar S, Gross HB, Keen CL. Changes in blood lipid parameters with chronic cranberry consumption in healthy human adults. FASEB J 2007;21:A1093.
24. Ridker PM. Clinical application of C-reactive protein for cardiovascular disease detection and prevention. Circulation 2003;107:363-9.
25. Paffen E, DeMaat MP. C-reactive protein in atherosclerosis: A causal factor? Cardiovasc Res 2006;71:30-9.
26. Libby P, Ridker PM. Inflammation and atherosclerosis: role of C-reactive protein in risk assessment. Am J Med 2004;116:9S-16S.
27. Ridker PM, Rifai N, Rose L, Buring JE, Cook NR. Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events. N Engl J Med 2002;347:1557-65.
28. Chun OK, Chung SJ, Claycombe KJ, Song WO. Serum C-reactive protein concentrations are inversely associated with dietary flavonoid intake in U.S. adults. J Nutr 2008;138:753-60.
29. Fröhlich M, Imhof A, Berg G, Hutchinson WL, Pepys MB, Boeing H, Muche R, Brenner H, Koenig W. Association between C-reactive protein and features of the metabolic syndrome: a population-based study. Diabetes Care 2000;23:1835-9.
30. Yudkin JS, Kumari M, Humphries SE, Mohamed-Ali V. Inflammation, obesity, stress and coronary heart disease: is interleukin-6 the link? Atherosclerosis 2000;148:209-14.
31. So MS, Lee JS, Yi SY. Induction of nutric oxide and cytokines in macrophages by codonopsis lanceolata. Korean J Food Sci Technol 2004;36:986-90.
32. Heinrich PC, Castell JV, Andus T. Interleukin-6 and the acute phase response. Biochem J 1990;265:621-36.
33. Bodet C, Chandad F, Grenier D. Anti-inflammatory activity of a high-molecular-weight cranberry fraction on macrophages stimulated by lipopolysaccharides from periodontopathogens. J Dent Res 2006;85:235-9.
34. Park HH, Lee S, Son HY, Park SB, Kim MS, Choi EJ, Singh TS, Ha JH, Lee MG, Kim JE, Hyun MC, Kwon TK, Kim YH, Kim SH. Flavonoids inhibit histamine release and expression of proinflammatory cytokines in mast cells. Arch Pharm Res 2008; 31:1303-11.
35. Barter PJ, Nicholls S, Rye KA, Anantharamaiah GM, Navab M, Fogelman AM. Antiinflammatory properties of HDL. Circ Res 2004;95:764-72.
36. Shin JU, Cho HK, Shin MS. Elevated tumor necrosis factor-α in stable angina pectoris. Korean Circ J 2000;30:861-6.
37. Muller CE, Khoo C, Percival SS. Cranberry polyphenols downregulate the toll-like receptor 4 pathway and NF-κB activation, while still enhancing tumor necrosis factor α secretion. FASEB J 2010;24:332.2.
38. Lira FS, Rosa JC, Pimentel GD, Tarini VA, Arida RM, Faloppa F, Alves ES, do Nascimento CO, Oyama LM, Seelaender M, de Mello MT, Santos RV. Inflammation and adipose tissue: effects of progressive load training in rats. Lipids Health Dis 2010;9:109.
39. von der Thüsen JH, Kuiper J, van Berkel TJ, Biessen EA. Interleukins in atherosclerosis: molecular pathways and therapeutic potential. Pharmacol Rev 2003;55:133-66.
40. Nabata T, Fukuo K, Morimoto S, Kitano S, Momose N, Hirotani A, Nakahashi T, Nishibe A, Hata S, Niinobu T, Suhara T, Shimizu M, Ohkuma H, Sakurai S, Nishimaki H, Ogihara T. Interleukin-2 modulates the responsiveness to angiotensin II in cultured vascular smooth muscle cells. Atherosclerosis 1997;133: 23-30.
41. Mao T, Van De Water J, Keen CL, Schmitz HH, Gershwin ME. Cocoa procyanidins and human cytokine transcription and secretion. J Nutr 2000;130:2093S-2099S.
42. Halvorsen B, Waehre T, Scholz H, Clausen OP, von der Thüsen JH, Müller F, Heimli H, Tonstad S, Hall C, Frøland SS, Biessen EA, Damås JK, Aukrust P. Interleukin-10 enhances the oxidized LDL-induced foam cell formation of macrophages by antiapoptotic mechanisms. J Lipid Res 2005;46:211-9.
43. Svajger U, Obermajer N, Jeras M. Dendritic cells treated with resveratrol during differentiation from monocytes gain substantial tolerogenic properties upon activation. Immunology 2010;129:525-35.
44. Iyer SS, Ghaffari AA, Cheng G. Lipopolysaccharide-mediated IL-10 transcriptional regulation requires sequential induction of type I IFNs and IL-27 in macrophages. J Immunol 2010;185: 6599-607.
45. Lakoski SG, Liu Y, Brosnihan KB, Herrington DM. Interleukin- 10 concentration and coronary heart disease (CHD) event risk in the estrogen replacement and atherosclerosis (ERA) study. Atherosclerosis 2008;197:443-7.
46. Deitschel SJ, Kerl ME, Chang CH, DeClue AE. Age-associated changes to pathogen-associated molecular pattern-induced inflammatory mediator production in dogs. J Vet Emerg Crit Care (San Antonio) 2010;20:494-502.
47. Hsieh NK, Wang JY, Liu JC, Wang SD, Chen HI. Nitric oxide inhibition accelerates hypertension and induces perivascular inflammation in rats. Clin Exp Pharmacol Physiol 2004;31:212-8.
48. Tokoudagba JM, Auger C, Bréant L, N'Gom S, Chabert P, Idris-Khodja N, Gbaguidi F, Gbenou J, Moudachirou M, Lobstein A, Schini-Kerth VB. Procyanidin-rich fractions from Parkia biglobosa (Mimosaceae) leaves cause redox-sensitive endotheliumdependent relaxation involving NO and EDHF in porcine coronary artery. J Ethnopharmacol 2010;132:246-50.
49. Maher MA, Mataczynski H, Stefaniak HM, Wilson T. Cranberry juice induces nitric oxide-dependent vasodilation in vitro and its infusion transiently reduces blood pressure in anesthetized rats. J Med Food 2000;3:141-7.