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Volumn 9, Issue 12, 2011, Pages 1593-1601

The proarrhythmic risk of cell therapy for cardiovascular diseases

Author keywords

cardiac regeneration; cardiovascular diseases; proarrhythmia; stem cell; transplantation

Indexed keywords

ARRHYTHMOGENESIS; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CELL MATURATION; EMBRYONIC STEM CELL; HEART FUNCTION; HEART MUSCLE CELL; HUMAN; MESENCHYMAL STEM CELL; MYOBLAST; PHENOTYPE; PROARRHYTHMIC RISK; REVIEW; STEM CELL; STEM CELL TRANSPLANTATION;

EID: 82755161193     PISSN: 14779072     EISSN: 17448344     Source Type: Journal    
DOI: 10.1586/erc.11.171     Document Type: Review
Times cited : (8)

References (114)
  • 1
    • 33646799069 scopus 로고    scopus 로고
    • Global and regional burden of disease and risk factors, 2001: Systematic analysis of population health data
    • DOI 10.1016/S0140-6736(06)68770-9, PII S0140673606687709
    • Lopez AD, Mathers CD, Ezzati M, Jamison DT, Murray CJ. Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data. Lancet 367(9524), 1747-1757 (2006). (Pubitemid 43767064)
    • (2006) Lancet , vol.367 , Issue.9524 , pp. 1747-1757
    • Lopez, A.D.1    Mathers, C.D.2    Ezzati, M.3    Jamison, D.T.4    Murray, C.J.5
  • 2
    • 57149134513 scopus 로고    scopus 로고
    • Long-term trends in the incidence of heart failure after myocardial infarction
    • Velagaleti RS, Pencina MJ, Murabito JM et al. Long-term trends in the incidence of heart failure after myocardial infarction. Circulation 118(20), 2057-2062 (2008).
    • (2008) Circulation , vol.118 , Issue.20 , pp. 2057-2062
    • Velagaleti, R.S.1    Pencina, M.J.2    Murabito, J.M.3
  • 3
    • 43749100265 scopus 로고    scopus 로고
    • Stem-cell-based therapy and lessons from the heart
    • DOI 10.1038/nature07040, PII NATURE07040
    • Passier R, Van Laake LW, Mummery CL. Stem-cell-based therapy and lessons from the heart. Nature 453(7193), 322-329 (2008). (Pubitemid 351693138)
    • (2008) Nature , vol.453 , Issue.7193 , pp. 322-329
    • Passier, R.1    Van Laake, L.W.2    Mummery, C.L.3
  • 4
    • 45149116677 scopus 로고    scopus 로고
    • The stem cell movement
    • Smart N, Riley PR. The stem cell movement. Circ. Res. 102(10), 1155-1168 (2008).
    • (2008) Circ. Res. , vol.102 , Issue.10 , pp. 1155-1168
    • Smart, N.1    Riley, P.R.2
  • 5
    • 42649122962 scopus 로고    scopus 로고
    • Stem cells in the heart: Whats the buzz all about? - Part 1: Preclinical considerations
    • Smith RR, Barile L, Messina E, Marban E. Stem cells in the heart: whats the buzz all about? - Part 1: preclinical considerations. Heart Rhythm 5(5), 749-757 (2008).
    • (2008) Heart Rhythm , vol.5 , Issue.5 , pp. 749-757
    • Smith, R.R.1    Barile, L.2    Messina, E.3    Marban, E.4
  • 8
    • 34547670282 scopus 로고    scopus 로고
    • Paracrine effects of direct intramyocardial implantation of bone marrow derived cells to enhance neovascularization in chronic ischaemic myocardium
    • Tse HF, Siu CW, Zhu SG et al. Paracrine effects of direct intramyocardial implantation of bone marrow derived cells to enhance neovascularization in chronic ischaemic myocardium. Eur. J. Heart Fail. 9(8), 747-753 (2007).
    • (2007) Eur. J. Heart Fail. , vol.9 , Issue.8 , pp. 747-753
    • Tse, H.F.1    Siu, C.W.2    Zhu, S.G.3
  • 9
    • 22144475112 scopus 로고    scopus 로고
    • Allogeneic mesenchymal stem cell transplantation in postinfarcted rat myocardium: Short- and long-term effects
    • DOI 10.1161/CIRCULATIONAHA.104.527937
    • Dai W, Hale SL, Martin BJ et al. Allogeneic mesenchymal stem cell transplantation in postinfarcted rat myocardium: short- and long-term effects. Circulation 112(2), 214-223 (2005). (Pubitemid 40982304)
    • (2005) Circulation , vol.112 , Issue.2 , pp. 214-223
    • Dai, W.1    Hale, S.L.2    Martin, B.J.3    Kuang, J.-Q.4    Dow, J.S.5    Wold, L.E.6    Kloner, R.A.7
  • 13
    • 70349661889 scopus 로고    scopus 로고
    • Engraftment, differentiation, and functional benefits of autologous cardiosphere-derived cells in porcine ischemic cardiomyopathy
    • Johnston PV, Sasano T, Mills K et al. Engraftment, differentiation, and functional benefits of autologous cardiosphere-derived cells in porcine ischemic cardiomyopathy. Circulation 120(12), 1075-1083 (2009).
    • (2009) Circulation , vol.120 , Issue.12 , pp. 1075-1083
    • Johnston, P.V.1    Sasano, T.2    Mills, K.3
  • 16
    • 78650085892 scopus 로고    scopus 로고
    • Proarrhythmic risk of embryonic stem cell-derived cardiomyocyte transplantation in infarcted myocardium
    • Liao SY, Liu Y, Siu CW et al. Proarrhythmic risk of embryonic stem cell-derived cardiomyocyte transplantation in infarcted myocardium. Heart Rhythm 7(12), 1852-1859 (2010).
    • (2010) Heart Rhythm , vol.7 , Issue.12 , pp. 1852-1859
    • Liao, S.Y.1    Liu, Y.2    Siu, C.W.3
  • 17
    • 0037417506 scopus 로고    scopus 로고
    • Angiogenesis in ischaemic myocardium by intramyocardial autologous bone marrow mononuclear cell implantation
    • DOI 10.1016/S0140-6736(03)12111-3
    • Tse HF, Kwong YL, Chan JK, Lo G, Ho CL, Lau CP. Angiogenesis in ischaemic myocardium by intramyocardial autologous bone marrow mononuclear cell implantation. Lancet 361(9351), 47-49 (2003). (Pubitemid 36050963)
    • (2003) Lancet , vol.361 , Issue.9351 , pp. 47-49
    • Tse, H.-F.1    Kwong, Y.-L.2    Chan, J.K.F.3    Lo, G.4    Ho, C.-L.5    Lau, C.-P.6
  • 18
    • 33645743539 scopus 로고    scopus 로고
    • Intracoronary bone marrow cell transfer after myocardial infarction: Eighteen months' follow-up data from the randomized, controlled BOOST (Bone marrow transfer to enhance ST-elevation infarct regeneration) trial
    • DOI 10.1161/CIRCULATIONAHA.105.575118, PII 0000301720060314000006
    • Meyer GP, Wollert KC, Lotz J et al. Intracoronary bone marrow cell transfer after myocardial infarction: eighteen months follow-up data from the randomized, controlled BOOST (Bone Marrow Transfer to Enhance ST-Elevation Infarct Regeneration) trial. Circulation 113(10), 1287-1294 (2006). (Pubitemid 43739450)
    • (2006) Circulation , vol.113 , Issue.10 , pp. 1287-1294
    • Meyer, G.P.1    Wollert, K.C.2    Lotz, J.3    Steffens, J.4    Lippolt, P.5    Fichtner, S.6    Hecker, H.7    Schaefer, A.8    Arseniev, L.9    Hertenstein, B.10    Ganser, A.11    Drexler, H.12
  • 19
    • 58249112859 scopus 로고    scopus 로고
    • One-year follow-up of feasibility and safety of the first U.S. randomized, controlled study using 3-dimensional guided catheter-based delivery of autologous skeletal myoblasts for ischemic cardiomyopathy (CAuSMIC study)
    • Dib N, Dinsmore J, Lababidi Z et al. One-year follow-up of feasibility and safety of the first U.S. randomized, controlled study using 3-dimensional guided catheter-based delivery of autologous skeletal myoblasts for ischemic cardiomyopathy (CAuSMIC study). JACC Cardiovasc. Interv. 2(1), 9-16 (2009).
    • (2009) JACC Cardiovasc. Interv. , vol.2 , Issue.1 , pp. 9-16
    • Dib, N.1    Dinsmore, J.2    Lababidi, Z.3
  • 20
    • 70549103270 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled, dose-escalation study of intravenous adult human mesenchymal stem cells (Prochymal) after acute myocardial infarction
    • Hare JM, Traverse JH, Henry TD et al. A randomized, double-blind, placebo-controlled, dose-escalation study of intravenous adult human mesenchymal stem cells (Prochymal) after acute myocardial infarction. J. Am. Coll. Cardiol. 54(24), 2277-2286 (2009).
    • (2009) J. Am. Coll. Cardiol. , vol.54 , Issue.24 , pp. 2277-2286
    • Hare, J.M.1    Traverse, J.H.2    Henry, T.D.3
  • 21
    • 78650663606 scopus 로고    scopus 로고
    • Stem cells in cardiac repair
    • Henning RJ. Stem cells in cardiac repair. Future Cardiol. 7(1), 99-117 (2011).
    • (2011) Future Cardiol. , vol.7 , Issue.1 , pp. 99-117
    • Henning, R.J.1
  • 22
    • 67249096636 scopus 로고    scopus 로고
    • Stem cell therapy for heart failure: Are arrhythmias a real safety concern?
    • Menasche P. Stem cell therapy for heart failure: are arrhythmias a real safety concern? Circulation 119(20), 2735-2740 (2009).
    • (2009) Circulation , vol.119 , Issue.20 , pp. 2735-2740
    • Menasche, P.1
  • 23
    • 73349097859 scopus 로고    scopus 로고
    • Electrophysiological challenges of cell-based myocardial repair
    • Chen HS, Kim C, Mercola M. Electrophysiological challenges of cell-based myocardial repair. Circulation 120(24), 2496-2508 (2009).
    • (2009) Circulation , vol.120 , Issue.24 , pp. 2496-2508
    • Chen, H.S.1    Kim, C.2    Mercola, M.3
  • 27
    • 77952242273 scopus 로고    scopus 로고
    • Human cardiospheres are a source of stem cells with cardiomyogenic potential
    • Davis DR, Ruckdeschel Smith R, Marban E. Human cardiospheres are a source of stem cells with cardiomyogenic potential. Stem Cells 28(5), 903-904 (2010).
    • (2010) Stem Cells , vol.28 , Issue.5 , pp. 903-904
    • Davis, D.R.1    Ruckdeschel Smith, R.2    Marban, E.3
  • 28
    • 61949300076 scopus 로고    scopus 로고
    • Functional cardiomyocytes derived from human induced pluripotent stem cells
    • Zhang J, Wilson GF, Soerens AG et al. Functional cardiomyocytes derived from human induced pluripotent stem cells. Circ. Res. 104(4), e30-e41 (2009).
    • (2009) Circ. Res. , vol.104 , Issue.4
    • Zhang, J.1    Wilson, G.F.2    Soerens, A.G.3
  • 29
    • 0037015228 scopus 로고    scopus 로고
    • Stem cell-derived cardiomyocytes demonstrate arrhythmic potential
    • DOI 10.1161/01.CIR.0000027585.05868.67
    • Zhang YM, Hartzell C, Narlow M, Dudley SC Jr. Stem cell-derived cardiomyocytes demonstrate arrhythmic potential. Circulation 106(10), 1294-1299 (2002). (Pubitemid 34988651)
    • (2002) Circulation , vol.106 , Issue.10 , pp. 1294-1299
    • Zhang, Y.M.1    Hartzell, C.2    Narlow, M.3    Dudley Jr., S.C.4
  • 30
    • 9644266750 scopus 로고    scopus 로고
    • Spontaneous and evoked intracellular calcium transients in donor-derived myocytes following intracardiac myoblast transplantation
    • DOI 10.1172/JCI200421589
    • Rubart M, Soonpaa MH, Nakajima H, Field LJ. Spontaneous and evoked intracellular calcium transients in donor-derived myocytes following intracardiac myoblast transplantation. J. Clin. Invest. 114(6), 775-783 (2004). (Pubitemid 39578736)
    • (2004) Journal of Clinical Investigation , vol.114 , Issue.6 , pp. 775-783
    • Rubart, M.1    Soonpaa, M.H.2    Nakajima, H.3    Field, L.J.4
  • 31
    • 0031055039 scopus 로고    scopus 로고
    • Disturbed connexin43 gap junction distribution correlates with the location of reentrant circuits in the epicardial border zone of healing canine infarcts that cause ventricular tachycardia
    • Peters NS, Coromilas J, Severs NJ, Wit AL. Disturbed connexin43 gap junction distribution correlates with the location of reentrant circuits in the epicardial border zone of healing canine infarcts that cause ventricular tachycardia. Circulation 95(4), 988-996 (1997). (Pubitemid 27091545)
    • (1997) Circulation , vol.95 , Issue.4 , pp. 988-996
    • Peters, N.S.1    Coromilas, J.2    Severs, N.J.3    Wit, A.L.4
  • 33
    • 0035035659 scopus 로고    scopus 로고
    • Sympathetic nerve sprouting, electrical remodeling and the mechanisms of sudden cardiac death
    • DOI 10.1016/S0008-6363(00)00308-4, PII S0008636300003084
    • Chen PS, Chen LS, Cao JM, Sharifi B, Karagueuzian HS, Fishbein MC. Sympathetic nerve sprouting, electrical remodeling and the mechanisms of sudden cardiac death. Cardiovasc. Res. 50(2), 409-416 (2001). (Pubitemid 32382168)
    • (2001) Cardiovascular Research , vol.50 , Issue.2 , pp. 409-416
    • Chen, P.-S.1    Chen, L.S.2    Cao, J.-M.3    Sharifi, B.4    Karagueuzian, H.S.5    Fishbein, M.C.6
  • 36
    • 82755188104 scopus 로고    scopus 로고
    • Cardiac regeneration therapy: Connections to cardiac physiology
    • doi:10.1152/ajpheart.00768.2011 Epub ahead of print
    • Takehara N, Matsubara H. Cardiac regeneration therapy: connections to cardiac physiology. Am. J. Physiol. Heart Circ. Physiol. doi:10.1152/ajpheart. 00768.2011 (2011) (Epub ahead of print).
    • (2011) Am. J. Physiol. Heart Circ. Physiol.
    • Takehara, N.1    Matsubara, H.2
  • 37
    • 77951101705 scopus 로고    scopus 로고
    • Repeated implantation of skeletal myoblast in a swine model of chronic myocardial infarction
    • Gavira JJ, Nasarre E, Abizanda G et al. Repeated implantation of skeletal myoblast in a swine model of chronic myocardial infarction. Eur. Heart J. 31(8), 1013-1021 (2010).
    • (2010) Eur. Heart J. , vol.31 , Issue.8 , pp. 1013-1021
    • Gavira, J.J.1    Nasarre, E.2    Abizanda, G.3
  • 38
    • 78651080136 scopus 로고    scopus 로고
    • In vivo assessment of the electrophysiological integration and arrhythmogenic risk of myocardial cell transplantation strategies
    • Gepstein L, Ding C, Rehemedula D et al. In vivo assessment of the electrophysiological integration and arrhythmogenic risk of myocardial cell transplantation strategies. Stem Cells 28(12), 2151-2161 (2010).
    • (2010) Stem Cells , vol.28 , Issue.12 , pp. 2151-2161
    • Gepstein, L.1    Ding, C.2    Rehemedula, D.3
  • 39
    • 67449092907 scopus 로고    scopus 로고
    • Myoblast transfer in ischemic heart failure: Effects on rhythm stability
    • Sherman W, He KL, Yi GH et al. Myoblast transfer in ischemic heart failure: effects on rhythm stability. Cell Transplant. 18(3), 333-341 (2009
    • (2009) Cell Transplant. , vol.18 , Issue.3 , pp. 333-341
    • Sherman, W.1    He, K.L.2    Yi, G.H.3
  • 42
    • 20044376124 scopus 로고    scopus 로고
    • Perkutane intramyokardiale implantation von autologen myoblasten bei ischamischer kardiomyopathie
    • DOI 10.1007/s00059-005-2623-7
    • Ince H, Petzsch M, Rehders TC, Kische S, Chatterjee T, Nienaber CA. [Percutaneous transplantation of autologous myoblasts in ischemic cardiomyopathy]. Herz 30(3), 223-231 (2005). (Pubitemid 40768455)
    • (2005) Herz , vol.30 , Issue.3 , pp. 223-231
    • Ince, H.1    Petzsch, M.2    Rehders, T.C.3    Kische, S.4    Chatterjee, T.5    Nienaber, C.A.6
  • 44
    • 79954545694 scopus 로고    scopus 로고
    • Final results of a Phase IIa, randomised, open-label trial to evaluate the percutaneous intramyocardial transplantation of autologous skeletal myoblasts in congestive heart failure patients: The SEISMIC trial
    • Duckers HJ, Houtgraaf J, Hehrlein C et al. Final results of a Phase IIa, randomised, open-label trial to evaluate the percutaneous intramyocardial transplantation of autologous skeletal myoblasts in congestive heart failure patients: the SEISMIC trial. EuroIntervention 6(7), 805-812 (2011).
    • (2011) EuroIntervention , vol.6 , Issue.7 , pp. 805-812
    • Duckers, H.J.1    Houtgraaf, J.2    Hehrlein, C.3
  • 46
    • 54449087401 scopus 로고    scopus 로고
    • A factor underlying late-phase arrhythmogenicity after cell therapy to the heart: Global downregulation of connexin43 in the host myocardium after skeletal myoblast transplantation
    • Coppen SR, Fukushima S, Shintani Y et al. A factor underlying late-phase arrhythmogenicity after cell therapy to the heart: global downregulation of connexin43 in the host myocardium after skeletal myoblast transplantation. Circulation 118(14 Suppl.), S138-S144 (2008).
    • (2008) Circulation , vol.118 , Issue.14 SUPPL.
    • Coppen, S.R.1    Fukushima, S.2    Shintani, Y.3
  • 48
    • 36249019756 scopus 로고    scopus 로고
    • Bone marrow mononuclear stem cells transplanted in rat enfarct myocardium improved the electrical conduction without evidence of proarrhythmic effects
    • DOI 10.3349/ymj.2007.48.5.754
    • Joung B, Kim IK, Lee MH, Yoo KJ, Kim SS. Bone marrow mononuclear stem cells transplanted in rat infarct myocardium improved the electrical conduction without evidence of proarrhythmic effects. Yonsei Med. J. 48(5), 754-764 (2007). (Pubitemid 350130464)
    • (2007) Yonsei Medical Journal , vol.48 , Issue.5 , pp. 754-764
    • Joung, B.1    Kim, I.-K.2    Lee, M.-H.3    Yoo, K.-J.4    Kim, S.-S.5
  • 52
    • 56449121207 scopus 로고    scopus 로고
    • Effects of intracoronary injection of mononuclear bone marrow cells on left ventricular function, arrhythmia risk profile, and restenosis after thrombolytic therapy of acute myocardial infarction
    • Huikuri HV, Kervinen K, Niemela M et al. Effects of intracoronary injection of mononuclear bone marrow cells on left ventricular function, arrhythmia risk profile, and restenosis after thrombolytic therapy of acute myocardial infarction. Eur. Heart J. 29(22), 2723-2732 (2008).
    • (2008) Eur. Heart J. , vol.29 , Issue.22 , pp. 2723-2732
    • Huikuri, H.V.1    Kervinen, K.2    Niemela, M.3
  • 55
    • 33751055085 scopus 로고    scopus 로고
    • Autologous transplantation of mononuclear bone marrow cells in patients with acute myocardial infarction: The effect of the dose of transplanted cells on myocardial function
    • Meluzin J, Mayer J, Groch L et al. Autologous transplantation of mononuclear bone marrow cells in patients with acute myocardial infarction: the effect of the dose of transplanted cells on myocardial function. Am. Heart J. 152(5), 975.e979-e915 (2006).
    • (2006) Am. Heart J. , vol.152 , Issue.5
    • Meluzin, J.1    Mayer, J.2    Groch, L.3
  • 56
    • 22944489232 scopus 로고    scopus 로고
    • Assessment of left ventricular segmental function after autologous bone marrow stem cells transplantation in patients with acute myocardial infarction by tissue tracking and strain imaging
    • Ruan W, Pan CZ, Huang GQ, Li YL, Ge JB, Shu XH. Assessment of left ventricular segmental function after autologous bone marrow stem cells transplantation in patients with acute myocardial infarction by tissue tracking and strain imaging. Chin. Med. J. (Engl.) 118(14), 1175-1181 (2005). (Pubitemid 41051617)
    • (2005) Chinese Medical Journal , vol.118 , Issue.14 , pp. 1175-1181
    • Ruan, W.1    Pan, C.-Z.2    Huang, G.-Q.3    Li, Y.-L.4    Ge, J.-B.5    Shu, X.-H.6
  • 59
    • 39849105758 scopus 로고    scopus 로고
    • Ventricular arrhythmias following intracoronary bone marrow stem cell transplantation
    • DOI 10.1093/europace/eum190
    • Villa A, Sanchez PL, Fernandez-Aviles F. Ventricular arrhythmias following intracoronary bone marrow stem cell transplantation. Europace 9(12), 1222-1223 (2007). (Pubitemid 351773251)
    • (2007) Europace , vol.9 , Issue.12 , pp. 1222-1223
    • Villa, A.1    Sanchez, P.L.2    Fernandez-Aviles, F.3
  • 62
    • 77955634793 scopus 로고    scopus 로고
    • Shock wave-pretreated bone marrow cells further improve left ventricular function after myocardial infarction in rabbits
    • Sheu JJ, Sun CK, Chang LT et al. Shock wave-pretreated bone marrow cells further improve left ventricular function after myocardial infarction in rabbits. Ann. Vasc. Surg. 24(6), 809-821 (2010).
    • (2010) Ann. Vasc. Surg. , vol.24 , Issue.6 , pp. 809-821
    • Sheu, J.J.1    Sun, C.K.2    Chang, L.T.3
  • 63
    • 48749128239 scopus 로고    scopus 로고
    • Autologous bone marrow-derived mononuclear cell therapy prevents the damage of viable myocardium and improves rat heart function following acute anterior myocardial infarction
    • Yip HK, Chang LT, Wu CJ et al. Autologous bone marrow-derived mononuclear cell therapy prevents the damage of viable myocardium and improves rat heart function following acute anterior myocardial infarction. Circ. J. 72(8), 1336-1345 (2008).
    • (2008) Circ. J. , vol.72 , Issue.8 , pp. 1336-1345
    • Yip, H.K.1    Chang, L.T.2    Wu, C.J.3
  • 64
    • 0030889354 scopus 로고    scopus 로고
    • Marrow stromal cells as stem cells for nonhematopoietic tissues
    • DOI 10.1126/science.276.5309.71
    • Prockop DJ. Marrow stromal cells as stem cells for nonhematopoietic tissues. Science 276(5309), 71-74 (1997). (Pubitemid 27161245)
    • (1997) Science , vol.276 , Issue.5309 , pp. 71-74
    • Prockop, D.J.1
  • 66
    • 0034766264 scopus 로고    scopus 로고
    • Isolation of human mesenchymal stem cells: Bone marrow versus umbilical cord blood
    • Mareschi K, Biasin E, Piacibello W, Aglietta M, Madon E, Fagioli F. Isolation of human mesenchymal stem cells: bone marrow versus umbilical cord blood. Haematologica 86(10), 1099-1100 (2001). (Pubitemid 33031878)
    • (2001) Haematologica , vol.86 , Issue.10 , pp. 1099-1100
    • Mareschi, K.1    Biasin, E.2    Piacibello, W.3    Aglietta, M.4    Madon, E.5    Fagioli, F.6
  • 67
    • 77949350004 scopus 로고    scopus 로고
    • Functional mesenchymal stem cells derived from human induced pluripotent stem cells attenuate limb ischemia in mice
    • Lian Q, Zhang Y, Zhang J et al. Functional mesenchymal stem cells derived from human induced pluripotent stem cells attenuate limb ischemia in mice. Circulation 121(9), 1113-1123 (2010).
    • (2010) Circulation , vol.121 , Issue.9 , pp. 1113-1123
    • Lian, Q.1    Zhang, Y.2    Zhang, J.3
  • 68
    • 48849114571 scopus 로고    scopus 로고
    • Forced alignment of mesenchymal stem cells undergoing cardiomyogenic differentiation affects functional integration with cardiomyocyte cultures
    • Pijnappels DA, Schalij MJ, Ramkisoensing AA et al. Forced alignment of mesenchymal stem cells undergoing cardiomyogenic differentiation affects functional integration with cardiomyocyte cultures. Circ. Res. 103(2), 167-176 (2008).
    • (2008) Circ. Res. , vol.103 , Issue.2 , pp. 167-176
    • Pijnappels, D.A.1    Schalij, M.J.2    Ramkisoensing, A.A.3
  • 69
    • 56249148884 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stromal cells express cardiac-specific markers retain the stromal phenotype, and do not become functional cardiomyocytes in vitro
    • Rose RA, Jiang H, Wang X et al. Bone marrow-derived mesenchymal stromal cells express cardiac-specific markers, retain the stromal phenotype, and do not become functional cardiomyocytes in vitro. Stem Cells 26(11), 2884-2892 (2008).
    • (2008) Stem Cells , vol.26 , Issue.11 , pp. 2884-2892
    • Rose, R.A.1    Jiang, H.2    Wang, X.3
  • 70
    • 69549138471 scopus 로고    scopus 로고
    • Allogeneic mesenchymal stem cells restore cardiac function in chronic ischemic cardiomyopathy via trilineage differentiating capacity
    • Quevedo HC, Hatzistergos KE, Oskouei BN et al. Allogeneic mesenchymal stem cells restore cardiac function in chronic ischemic cardiomyopathy via trilineage differentiating capacity. Proc. Natl Acad. Sci. USA 106(33), 14022-14027 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , Issue.33 , pp. 14022-14027
    • Quevedo, H.C.1    Hatzistergos, K.E.2    Oskouei, B.N.3
  • 71
    • 0036266426 scopus 로고    scopus 로고
    • Mesenchymal stem cell implantation in a swine myocardial infarct model: Engraftment and functional effects
    • discussion 1926
    • Shake JG, Gruber PJ, Baumgartner WA et al. Mesenchymal stem cell implantation in a swine myocardial infarct model: engraftment and functional effects. Ann. Thorac. Surg. 73(6), 1919-1925; discussion 1926 (2002).
    • (2002) Ann. Thorac. Surg. , vol.73 , Issue.6 , pp. 1919-1925
    • Shake, J.G.1    Gruber, P.J.2    Baumgartner, W.A.3
  • 73
    • 80055045664 scopus 로고    scopus 로고
    • Mesenchymal stem cell injection ameliorates the inducibility of ventricular arrhythmias after myocardial infarction in rats
    • Wang D, Zhang F, Shen W et al. Mesenchymal stem cell injection ameliorates the inducibility of ventricular arrhythmias after myocardial infarction in rats. Int. J. Cardiol. 152(3), 314-320 (2010).
    • (2010) Int. J. Cardiol. , vol.152 , Issue.3 , pp. 314-320
    • Wang, D.1    Zhang, F.2    Shen, W.3
  • 74
    • 70349538996 scopus 로고    scopus 로고
    • Endocardial electrogram analysis after intramyocardial injection of mesenchymal stem cells in the chronic ischemic myocardium
    • Krause K, Schneider C, Lange C et al. Endocardial electrogram analysis after intramyocardial injection of mesenchymal stem cells in the chronic ischemic myocardium. Pacing Clin. Electrophysiol. 32(10), 1319-1328 (2009).
    • (2009) Pacing Clin. Electrophysiol. , vol.32 , Issue.10 , pp. 1319-1328
    • Krause, K.1    Schneider, C.2    Lange, C.3
  • 75
    • 33746285271 scopus 로고    scopus 로고
    • Effects of autologous stem cell transplantation on ventricular electrophysiology in doxorubicin-induced heart failure
    • DOI 10.1016/j.cellbi.2006.03.002, PII S1065699506000655
    • Chen M, Fan ZC, Liu XJ et al. Effects of autologous stem cell transplantation on ventricular electrophysiology in doxorubicin-induced heart failure. Cell Biol. Int. 30(7), 576-582 (2006). (Pubitemid 44107716)
    • (2006) Cell Biology International , vol.30 , Issue.7 , pp. 576-582
    • Chen, M.1    Fan, Z.-C.2    Liu, X.-J.3    Deng, J.-L.4    Zhang, L.5    Rao, L.6    Yang, Q.7    Huang, D.-J.8
  • 79
    • 33750703672 scopus 로고    scopus 로고
    • Intracoronary transplantation of autologous bone marrow mesenchymal stem cells for ischemic cardiomyopathy due to isolated chronic occluded left anterior descending artery
    • Chen S, Liu Z, Tian N et al. Intracoronary transplantation of autologous bone marrow mesenchymal stem cells for ischemic cardiomyopathy due to isolated chronic occluded left anterior descending artery. J. Invasive Cardiol. 18(11), 552-556 (2006). (Pubitemid 44704523)
    • (2006) Journal of Invasive Cardiology , vol.18 , Issue.11 , pp. 552-556
    • Chen, S.1    Liu, Z.2    Tian, N.3    Zhang, J.4    Yei, F.5    Duan, B.6    Zhu, Z.7    Lin, S.8    Kwan, T.W.9
  • 80
    • 33947178490 scopus 로고    scopus 로고
    • Electrophysiological effects of intracoronary transplantation of autologous mesenchymal and endothelial progenitor cells
    • DOI 10.1093/europace/eul184
    • Katritsis DG, Sotiropoulou P, Giazitzoglou E, Karvouni E, Papamichail M. Electrophysiological effects of intracoronary transplantation of autologous mesenchymal and endothelial progenitor cells. Europace 9(3), 167-171 (2007). (Pubitemid 46404162)
    • (2007) Europace , vol.9 , Issue.3 , pp. 167-171
    • Katritsis, D.G.1    Sotiropoulou, P.2    Giazitzoglou, E.3    Karvouni, E.4    Papamichail, M.5
  • 81
    • 78449245815 scopus 로고    scopus 로고
    • A novel approach to transplanting bone marrow stem cells to repair human myocardial infarction: Delivery via a noninfarct-relative artery
    • Yang Z, Zhang F, Ma W et al. A novel approach to transplanting bone marrow stem cells to repair human myocardial infarction: delivery via a noninfarct-relative artery. Cardiovasc. Ther. 28(6), 380-385 (2010).
    • (2010) Cardiovasc. Ther. , vol.28 , Issue.6 , pp. 380-385
    • Yang, Z.1    Zhang, F.2    Ma, W.3
  • 82
    • 79952405279 scopus 로고    scopus 로고
    • Rationale and design of the Transendocardial Injection of Autologous Human Cells (bone marrow or mesenchymal) in Chronic Ischemic Left Ventricular Dysfunction and Heart Failure Secondary to Myocardial Infarction (TAC-HFT) trial: A randomized, double-blind, placebo-controlled study of safety and efficacy
    • Trachtenberg B, Velazquez DL, Williams AR et al. Rationale and design of the Transendocardial Injection of Autologous Human Cells (bone marrow or mesenchymal) in Chronic Ischemic Left Ventricular Dysfunction and Heart Failure Secondary to Myocardial Infarction (TAC-HFT) trial: a randomized, double-blind, placebo-controlled study of safety and efficacy. Am. Heart J. 161(3), 487-493 (2011).
    • (2011) Am. Heart J. , vol.161 , Issue.3 , pp. 487-493
    • Trachtenberg, B.1    Velazquez, D.L.2    Williams, A.R.3
  • 85
    • 33646199622 scopus 로고    scopus 로고
    • Proarrhythmic potential of mesenchymal stem cell transplantation revealed in an in vitro coculture model
    • DOI 10.1161/CIRCULATIONAHA.105.593038, PII 0000301720060418000006
    • Chang MG, Tung L, Sekar RB et al. Proarrhythmic potential of mesenchymal stem cell transplantation revealed in an in vitro coculture model. Circulation 113(15), 1832-1841 (2006). (Pubitemid 43739394)
    • (2006) Circulation , vol.113 , Issue.15 , pp. 1832-1841
    • Chang, M.G.1    Tung, L.2    Sekar, R.B.3    Chang, C.Y.4    Cysyk, J.5    Dong, P.6    Marban, E.7    Abraham, M.R.8
  • 87
    • 0034663515 scopus 로고    scopus 로고
    • Adult rat and human bone marrow stromal cells differentiate into neurons
    • DOI 10.1002/1097-4547(20000815)61:4<364::AID-JNR2>3.0.CO;2-C
    • Woodbury D, Schwarz EJ, Prockop DJ, Black IB. Adult rat and human bone marrow stromal cells differentiate into neurons. J. Neurosci. Res. 61(4), 364-370 (2000). (Pubitemid 30620221)
    • (2000) Journal of Neuroscience Research , vol.61 , Issue.4 , pp. 364-370
    • Woodbury, D.1    Schwarz, E.J.2    Prockop, D.J.3    Black, I.B.4
  • 89
    • 77953620382 scopus 로고    scopus 로고
    • Cardiac cell therapy with mesenchymal stem cell induces cardiac nerve sprouting, angiogenesis, and reduced connexin43- positive gap junctions, but concomitant electrical pacing increases connexin43- positive gap junctions in canine heart
    • Kim SK, Pak HN, Park JH et al. Cardiac cell therapy with mesenchymal stem cell induces cardiac nerve sprouting, angiogenesis, and reduced connexin43- positive gap junctions, but concomitant electrical pacing increases connexin43- positive gap junctions in canine heart. Cardiol. Young 20(3), 308-317 (2010).
    • (2010) Cardiol. Young , vol.20 , Issue.3 , pp. 308-317
    • Kim, S.K.1    Pak, H.N.2    Park, J.H.3
  • 91
    • 79959819263 scopus 로고    scopus 로고
    • De novo cardiomyocytes from within the activated adult heart after injury
    • Smart N, Bollini S, Dube KN et al. De novo cardiomyocytes from within the activated adult heart after injury. Nature 474(7353), 640-644 (2011).
    • (2011) Nature , vol.474 , Issue.7353 , pp. 640-644
    • Smart, N.1    Bollini, S.2    Dube, K.N.3
  • 94
    • 77953726551 scopus 로고    scopus 로고
    • Isolation and expansion of functionally-competent cardiac progenitor cells directly from heart biopsies
    • Davis DR, Kizana E, Terrovitis J et al. Isolation and expansion of functionally-competent cardiac progenitor cells directly from heart biopsies. J. Mol. Cell. Cardiol. 49(2), 312-321 (2010).
    • (2010) J. Mol. Cell. Cardiol. , vol.49 , Issue.2 , pp. 312-321
    • Davis, D.R.1    Kizana, E.2    Terrovitis, J.3
  • 95
    • 33847145871 scopus 로고    scopus 로고
    • Regenerative potential of cardiosphere-derived cells expanded from percutaneous endomyocardial biopsy specimens
    • DOI 10.1161/CIRCULATIONAHA.106.655209, PII 0000301720070220000015
    • Smith RR, Barile L, Cho HC et al. Regenerative potential of cardiosphere-derived cells expanded from percutaneous endomyocardial biopsy specimens. Circulation 115(7), 896-908 (2007). (Pubitemid 46294730)
    • (2007) Circulation , vol.115 , Issue.7 , pp. 896-908
    • Smith, R.R.1    Barile, L.2    Cho, H.C.3    Leppo, M.K.4    Hare, J.M.5    Messina, E.6    Giacomello, A.7    Abraham, M.R.8    Marban, E.9
  • 96
    • 79955367836 scopus 로고    scopus 로고
    • Improvements of cardiac electrophysiologic stability and ventricular fibrillation threshold in rats with myocardial infarction treated with cardiac stem cells
    • Zheng S, Zhou C, Weng Y et al. Improvements of cardiac electrophysiologic stability and ventricular fibrillation threshold in rats with myocardial infarction treated with cardiac stem cells. Crit. Care Med. 39(5), 1082-1088 (2011).
    • (2011) Crit. Care Med. , vol.39 , Issue.5 , pp. 1082-1088
    • Zheng, S.1    Zhou, C.2    Weng, Y.3
  • 97
    • 48049109419 scopus 로고    scopus 로고
    • Local activation or implantation of cardiac progenitor cells rescues scarred infarcted myocardium improving cardiac function
    • Rota M, Padin-Iruegas ME, Misao Y et al. Local activation or implantation of cardiac progenitor cells rescues scarred infarcted myocardium improving cardiac function. Circ. Res. 103(1), 107-116 (2008).
    • (2008) Circ. Res. , vol.103 , Issue.1 , pp. 107-116
    • Rota, M.1    Padin-Iruegas, M.E.2    Misao, Y.3
  • 99
    • 0037144701 scopus 로고    scopus 로고
    • Characterization and enrichment of cardiomyocytes derived from human embryonic stem cells
    • Xu C, Police S, Rao N, Carpenter MK. Characterization and enrichment of cardiomyocytes derived from human embryonic stem cells. Circ. Res. 91(6), 501-508 (2002).
    • (2002) Circ. Res. , vol.91 , Issue.6 , pp. 501-508
    • Xu, C.1    Police, S.2    Rao, N.3    Carpenter, M.K.4
  • 110
    • 0038300672 scopus 로고    scopus 로고
    • Human embryonic stem cells develop into multiple types of cardiac myocytes: Action potential characterization
    • DOI 10.1161/01.RES.0000080317.92718.99
    • He JQ, Ma Y, Lee Y, Thomson JA, Kamp TJ. Human embryonic stem cells develop into multiple types of cardiac myocytes: action potential characterization. Circ. Res. 93(1), 32-39 (2003). (Pubitemid 36859038)
    • (2003) Circulation Research , vol.93 , Issue.1 , pp. 32-39
    • He, J.-Q.1    Ma, Y.2    Lee, Y.3    Thomson, J.A.4    Kamp, T.J.5
  • 111
    • 11244249952 scopus 로고    scopus 로고
    • Functional integration of electrically active cardiac derivatives from genetically engineered human embryonic stem cells with quiescent recipient ventricular cardiomyocytes: Insights into the development of cell-based pacemakers
    • DOI 10.1161/01.CIR.0000151313.18547.A2
    • Xue T, Cho HC, Akar FG et al. Functional integration of electrically active cardiac derivatives from genetically engineered human embryonic stem cells with quiescent recipient ventricular cardiomyocytes: insights into the development of cell-based pacemakers. Circulation 111(1), 11-20 (2005). (Pubitemid 40070838)
    • (2005) Circulation , vol.111 , Issue.1 , pp. 11-20
    • Xue, T.1    Cho, H.C.2    Akar, F.G.3    Tsang, S.-Y.4    Jones, S.P.5    Marban, E.6    Tomaselli, G.F.7    Li, R.A.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.