A pivotal role for antigen-presenting cells overexpressing SOCS3 in controlling invariant NKT cell responses during collagen-induced arthritis

Annals of the Rheumatic Diseases

Volumn 70, Issue 12, 2011, Pages 2167-2175

  Veenbergen, Sharon ^a   Bennink, Miranda B ^a   Affandi, Alsya J ^a   Bessis, Natacha ^b   Biton, Jérôme ^b   Arntz, Onno J ^a   Van Den Berg, Wim B ^a   Van De Loo, Fons A J ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b University of Paris   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; ALPHA GALACTOSYLCERAMIDE; CD1D ANTIGEN; CD69 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; SUPPRESSOR OF CYTOKINE SIGNALING 3;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN PRESENTING CELL; ARTHRITIS; ARTICLE; CELL EXPANSION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; FLOW CYTOMETRY; GENE OVEREXPRESSION; IMMUNOREGULATION; LIVER; MALE; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPLEEN; T LYMPHOCYTE ACTIVATION; VIRAL GENE DELIVERY SYSTEM;

ADENOVIRIDAE; ANIMALS; ANTIGEN-PRESENTING CELLS; ANTIGENS, CD1D; ARTHRITIS, EXPERIMENTAL; CELLS, CULTURED; CYTOKINES; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; KILLER CELLS, NATURAL; LIVER; LYMPHOCYTE ACTIVATION; MACROPHAGES; MALE; MICE; MICE, INBRED DBA; SPLEEN; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS;

EID: 82755160834     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/ard.2011.154815     Document Type: Article

References (49)

1. Godfrey DI, MacDonald HR, Kronenberg M, et al. NKT cells: what's in a name? Nat Rev Immunol 2004;4:231-7. (Pubitemid 38339089)
2. Matsuda JL, Naidenko OV, Gapin L, et al. Tracking the response of natural killer T cells to a glycolipid antigen using CD1d tetramers. J Exp Med 2000;192:741-54.
3. Bendelac A. CD1: presenting unusual antigens to unusual T lymphocytes. Science 1995;269:185-6.
4. Lantz O, Bendelac A. An invariant T cell receptor alpha chain is used by a unique subset of major histocompatibility complex class I-specific CD4+ and CD4-8- T cells in mice and humans. J Exp Med 1994;180:1097-106. (Pubitemid 24256622)
5. Kawano T, Cui J, Koezuka Y, et al. CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides. Science 1997;278:1626-9. (Pubitemid 27516282)
6. Park SH, Benlagha K, Lee D, et al. Unaltered phenotype, tissue distribution and function of Valpha14(+) NKT cells in germ-free mice. Eur J Immunol 2000;30:620-5. (Pubitemid 30098856)
7. Matsuda JL, Mallevaey T, Scott-Browne J, et al. CD1d-restricted iNKT cells, the 'Swiss-Army knife' of the immune system. Curr Opin Immunol 2008;20:358-68.
8. Drennan MB, Aspeslagh S, Elewaut D. Invariant natural killer T cells in rheumatic disease: a joint dilemma. Nat Rev Rheumatol 2010;6:90-8.
9. Coppieters K, Van Beneden K, Jacques P, et al. A single early activation of invariant NK T cells confers long-term protection against collagen-induced arthritis in a ligand-specific manner. J Immunol 2007;179:2300-9.
10. Miellot A, Zhu R, Diem S, et al. Activation of invariant NK T cells protects against experimental rheumatoid arthritis by an IL-10-dependent pathway. Eur J Immunol 2005;35:3704-13. (Pubitemid 43025550)
11. Chiba A, Kaieda S, Oki S, et al. The involvement of V(alpha)14 natural killer T cells in the pathogenesis of arthritis in murine models. Arthritis Rheum 2005;52:1941-8. (Pubitemid 40852903)
12. Kim HY, Kim HJ, Min HS, et al. NKT cells promote antibody-induced joint inflammation by suppressing transforming growth factor beta1 production. J Exp Med 2005;201:41-7. (Pubitemid 40130082)
13. Trappeniers M, Goormans S, Van Beneden K, et al. Synthesis and in vitro evaluation of alpha-GalCer epimers. ChemMedChem 2008;3:1061-70.
14. Ilangumaran S, Ramanathan S, Rottapel R. Regulation of the immune system by SOCS family adaptor proteins. Semin Immunol 2004;16:351-65. (Pubitemid 39488017)
15. Mansell A, Smith R, Doyle SL, et al. Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation. Nat Immunol 2006;7:148-55. (Pubitemid 43135880)
16. Yoshimura A, Naka T, Kubo M. SOCS proteins, cytokine signalling and immune regulation. Nat Rev Immunol 2007;7:454-65. (Pubitemid 46834848)
17. Veenbergen S, Bennink MB, de Hooge AS, et al. Splenic suppressor of cytokine signaling 3 transgene expression affects T cell responses and prevents development of collagen-induced arthritis. Arthritis Rheum 2008;58:3742-52.
18. Bendelac A, Lantz O, Quimby ME, et al. CD1 recognition by mouse NK1+ T lymphocytes. Science 1995;268:863-5.
19. Geurts J, Joosten LA, Takahashi N, et al. Computational design and application of endogenous promoters for transcriptionally targeted gene therapy for rheumatoid arthritis. Mol Ther 2009;17:1877-87.
20. Chartier C, Degryse E, Gantzer M, et al. Efficient generation of recombinant adenovirus vectors by homologous recombination in Escherichia coli. J Virol 1996;70:4805-10. (Pubitemid 26187479)
21. Smeets RL, van de Loo FA, Joosten LA, et al. Effectiveness of the soluble form of the interleukin-1 receptor accessory protein as an inhibitor of interleukin-1 in collagen-induced arthritis. Arthritis Rheum 2003;48:2949-58. (Pubitemid 37280625)
22. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987;162:156-9. (Pubitemid 17064313)
23. Smeets RL, Veenbergen S, Arntz OJ, et al. A novel role for suppressor of cytokine signaling 3 in cartilage destruction via induction of chondrocyte desensitization toward insulin-like growth factor. Arthritis Rheum 2006;54:1518-28.
24. Brigl M, Bry L, Kent SC, et al. Mechanism of CD1d-restricted natural killer T cell activation during microbial infection. Nat Immunol 2003;4:1230-7. (Pubitemid 37540692)
25. Sada-Ovalle I, Chiba A, Gonzales A, et al. Innate invariant NKT cells recognize Mycobacterium tuberculosis-infected macrophages, produce interferon-gamma, and kill intracellular bacteria. PLoS Pathog 2008;4:e1000239.
26. Nagarajan NA, Kronenberg M. Invariant NKT cells amplify the innate immune response to lipopolysaccharide. J Immunol 2007;178:2706-13. (Pubitemid 46335652)
27. Johnson M, Huyn S, Burton J, et al. Differential biodistribution of adenoviral vector in vivo as monitored by bioluminescence imaging and quantitative polymerase chain reaction. Hum Gene Ther 2006;17:1262-9. (Pubitemid 44975142)
28. Stone D, Liu Y, Shayakhmetov D, et al. Adenovirus-platelet interaction in blood causes virus sequestration to the reticuloendothelial system of the liver. J Virol 2007;81:4866-71. (Pubitemid 46668683)
29. Sköld M, Xiong X, Illarionov PA, et al. Interplay of cytokines and microbial signals in regulation of CD1d expression and NKT cell activation. J Immunol 2005;175:3584-93. (Pubitemid 41292017)
30. Mattner J, Debord KL, Ismail N, et al. Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections. Nature 2005;434:525-9. (Pubitemid 40477062)
31. Baxevanis CN, Gritzapis AD, Papamichail M. In vivo antitumor activity of NKT cells activated by the combination of IL-12 and IL-18. J Immunol 2003;171:2953-9. (Pubitemid 37093517)
32. Zhu R, Diem S, Araujo LM, et al. The Pro-Th1 cytokine IL-12 enhances IL-4 production by invariant NKT cells: relevance for T cell-mediated hepatitis. J Immunol 2007;178:5435-42. (Pubitemid 46674337)
33. Leite-De-Moraes MC, Hameg A, Pacilio M, et al. IL-18 enhances IL-4 production by ligand-activated NKT lymphocytes: a pro-Th2 effect of IL-18 exerted through NKT cells. J Immunol 2001;166:945-51. (Pubitemid 32060249)
34. de Waal Malefyt R, Haanen J, Spits H, et al. Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression. J Exp Med 1991;174:915-24.
35. Li MO, Flavell RA. Contextual regulation of inflammation: a duet by transforming growth factor-beta and interleukin-10. Immunity 2008;28:468-76. (Pubitemid 351467045)
36. Taga K, Tosato G. IL-10 inhibits human T cell proliferation and IL-2 production. J Immunol 1992;148:1143-8.
37. Joosten LA, Lubberts E, Durez P, et al. Role of interleukin-4 and interleukin-10 in murine collagen-induced arthritis. Protective effect of interleukin-4 and interleukin-10 treatment on cartilage destruction. Arthritis Rheum 1997;40:249-60. (Pubitemid 27114088)
38. Cassatella MA, Gasperini S, Bovolenta C, et al. Interleukin-10 (IL-10) selectively enhances CIS3/SOCS3 mRNA expression in human neutrophils: evidence for an IL-10-induced pathway that is independent of STAT protein activation. Blood 1999;94:2880-9. (Pubitemid 29477317)
39. Niemand C, Nimmesgern A, Haan S, et al. Activation of STAT3 by IL-6 and IL-10 in primary human macrophages is differentially modulated by suppressor of cytokine signaling 3. J Immunol 2003;170:3263-72. (Pubitemid 36302204)
40. Nakaya M, Hashimoto M, Nakagawa R, et al. SOCS3 in T and NKT cells negatively regulates cytokine production and ameliorates ConA-induced hepatitis. J Immunol 2009;183:7047-53.
41. Tomura M, Yu WG, Ahn HJ, et al. A novel function of Valpha14+CD4+NKT cells: stimulation of IL-12 production by antigen-presenting cells in the innate immune system. J Immunol 1999;163:93-101. (Pubitemid 29295829)
42. Kitamura H, Iwakabe K, Yahata T, et al. The natural killer T (NKT) cell ligand alpha-galactosylceramide demonstrates its immunopotentiating effect by inducing interleukin (IL)-12 production by dendritic cells and IL-12 receptor expression on NKT cells. J Exp Med 1999;189:1121-8.
43. Vincent MS, Leslie DS, Gumperz JE, et al. CD1-dependent dendritic cell instruction. Nat Immunol 2002;3:1163-8.
44. Uemura Y, Liu TY, Narita Y, et al. Cytokine-dependent modification of IL-12p70 and IL-23 balance in dendritic cells by ligand activation of Valpha24 invariant NKT cells. J Immunol 2009;183:201-8.
45. Teige A, Bockermann R, Hasan M, et al. CD1d-dependent NKT cells play a protective role in acute and chronic arthritis models by ameliorating antigen-specific Th1 responses. J Immunol 2010;185:345-56.
46. Miellot-Gafsou A, Biton J, Bourgeois E, et al. Early activation of invariant natural killer T cells in a rheumatoid arthritis model and application to disease treatment. Immunology 2010;130:296-306.
47. Spiegel S, Milstien S. The outs and the ins of sphingosine-1-phosphate in immunity. Nat Rev Immunol 2011;11:403-15.
48. Nishimura T, Kitamura H, I wakabe K, et al. The interface between innate and acquired immunity: glycolipid antigen presentation by CD1d-expressing dendritic cells to NKT cells induces the differentiation of antigen-specific cytotoxic T lymphocytes. Int Immunol 2000;12:987-94. (Pubitemid 30601366)
49. Singh N, Hong S, Scherer DC, et al. Cutting edge: activation of NK T cells by CD1d and alpha-galactosylceramide directs conventional T cells to the acquisition of a Th2 phenotype. J Immunol 1999;163:2373-7. (Pubitemid 29399153)