S-glutathionylation of cysteine 99 in the APE1 protein impairs abasic endonuclease activity

Journal of Molecular Biology

Volumn 414, Issue 3, 2011, Pages 313-326

  Kim, Yun Jeong ^a   Kim, Daemyung ^b   Illuzzi, Jennifer L ^a   Delaplane, Sarah ^c,d   Su, Dian ^e   Bernier, Michel ^a   Gross, Michael L ^e   Georgiadis, Millie M ^c,d   Wilson III, David M ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b Chongju University   (South Korea)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d INDIANA UNIVERSITY   (United States)

^e WASHINGTON UNIVERSITY   (United States)

Author keywords

APEX1; base excision DNA repair; cysteine glutathionylation; posttranslational modification; redox regulation

Indexed keywords

ENDONUCLEASE; GLUTATHIONE; PROTEIN APE1; UNCLASSIFIED DRUG;

ARTICLE; DNA REPAIR; ENZYME ACTIVITY; EXCISION REPAIR; HUMAN; HUMAN CELL; MASS SPECTROMETRY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN MODIFICATION; SITE DIRECTED MUTAGENESIS;

EID: 82555168294     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2011.10.023     Document Type: Article

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