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Volumn 1, Issue 2, 2010, Pages 147-157

Intensive care unit-acquired weakness (ICUAW) and muscle wasting in critically ill patients with severe sepsis and septic shock

Author keywords

CIP CIM; Critical illness myopathy; ICU acquired weakness; Immunity; Multiple organ failure; Systemic inflammation

Indexed keywords

COMPLEMENT COMPONENT C3A; COMPLEMENT COMPONENT C5A; GLUCOCORTICOID; HYDROCORTISONE; INSULIN; INTERLEUKIN 1; INTERLEUKIN 6; MYOSIN HEAVY CHAIN; PANCURONIUM; STEROID; TUMOR NECROSIS FACTOR ALPHA; UBIQUITIN PROTEIN LIGASE E3; VECURONIUM;

EID: 82455195617     PISSN: 21905991     EISSN: 21906009     Source Type: Journal    
DOI: 10.1007/s13539-010-0010-6     Document Type: Review
Times cited : (189)

References (124)
  • 3
    • 0037426726 scopus 로고    scopus 로고
    • The pathophysiology and treatment of sepsis
    • Hotchkiss RS, Karl IE. The pathophysiology and treatment of sepsis. N Engl J Med. 2003; 348: 138-50.
    • (2003) N Engl J Med , vol.348 , pp. 138-150
    • Hotchkiss, R.S.1    Karl, I.E.2
  • 4
    • 37549020378 scopus 로고    scopus 로고
    • Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2008
    • Dellinger RP, Levy MM, Carlet JM, Bion J, Parker MM, Jaeschke R, et al. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2008. Crit Care Med. 2008; 36: 296-327.
    • (2008) Crit Care Med , vol.36 , pp. 296-327
    • Dellinger, R.P.1    Levy, M.M.2    Carlet, J.M.3    Bion, J.4    Parker, M.M.5    Jaeschke, R.6
  • 5
    • 0026874127 scopus 로고
    • American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis
    • American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 1992; 20: 864-74.
    • (1992) Crit Care Med , vol.20 , pp. 864-874
  • 6
    • 0025891436 scopus 로고
    • Sepsis, the sepsis syndrome, multi-organ failure: a plea for comparable definitions
    • Bone RC. Sepsis, the sepsis syndrome, multi-organ failure: a plea for comparable definitions. Ann Intern Med. 1991; 114: 332-3.
    • (1991) Ann Intern Med , vol.114 , pp. 332-333
    • Bone, R.C.1
  • 7
    • 0029903114 scopus 로고    scopus 로고
    • Sir Isaac Newton, sepsis, SIRS, and CARS
    • Bone RC. Sir Isaac Newton, sepsis, SIRS, and CARS. Crit Care Med. 1996; 24: 1125-8.
    • (1996) Crit Care Med , vol.24 , pp. 1125-1128
    • Bone, R.C.1
  • 8
    • 0034958947 scopus 로고    scopus 로고
    • Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care
    • Angus DC, Linde-Zwirble WT, Lidicker J, Clermont G, Carcillo J, Pinsky MR. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med. 2001; 29: 1303-10.
    • (2001) Crit Care Med , vol.29 , pp. 1303-1310
    • Angus, D.C.1    Linde-Zwirble, W.T.2    Lidicker, J.3    Clermont, G.4    Carcillo, J.5    Pinsky, M.R.6
  • 9
    • 0037451929 scopus 로고    scopus 로고
    • The epidemiology of sepsis in the United States from 1979 through 2000
    • Martin GS, Mannino DM, Eaton S, Moss M. The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med. 2003; 348: 1546-54.
    • (2003) N Engl J Med , vol.348 , pp. 1546-1554
    • Martin, G.S.1    Mannino, D.M.2    Eaton, S.3    Moss, M.4
  • 10
  • 11
    • 0036390209 scopus 로고    scopus 로고
    • Direct costs of severe sepsis in three German intensive care units based on retrospective electronic patient record analysis of resource use
    • Moerer O, Schmid A, Hofmann M, Herklotz A, Reinhart K, Werdan K, et al. Direct costs of severe sepsis in three German intensive care units based on retrospective electronic patient record analysis of resource use. Intensive Care Med. 2002; 28: 1440-6.
    • (2002) Intensive Care Med , vol.28 , pp. 1440-1446
    • Moerer, O.1    Schmid, A.2    Hofmann, M.3    Herklotz, A.4    Reinhart, K.5    Werdan, K.6
  • 13
    • 0035829842 scopus 로고    scopus 로고
    • Early goal-directed therapy in the treatment of severe sepsis and septic shock
    • Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B, et al. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med. 2001; 345: 1368-77.
    • (2001) N Engl J Med , vol.345 , pp. 1368-1377
    • Rivers, E.1    Nguyen, B.2    Havstad, S.3    Ressler, J.4    Muzzin, A.5    Knoblich, B.6
  • 14
    • 0037151571 scopus 로고    scopus 로고
    • Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock
    • Annane D, Sébille V, Charpentier C, Bollaert P, François B, Korach J, et al. Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock. JAMA. 2002; 288: 862-71.
    • (2002) Jama , vol.288 , pp. 862-871
    • Annane, D.1    Sébille, V.2    Charpentier, C.3    Bollaert, P.4    François, B.5    Korach, J.6
  • 19
    • 63249128249 scopus 로고    scopus 로고
    • Intensive versus conventional glucose control in critically ill patients
    • Finfer S, Chittock DR, Su SY, Blair D, Foster D, Dhingra V, et al. Intensive versus conventional glucose control in critically ill patients. N Engl J Med. 2009; 360: 1283-97.
    • (2009) N Engl J Med , vol.360 , pp. 1283-1297
    • Finfer, S.1    Chittock, D.R.2    Su, S.Y.3    Blair, D.4    Foster, D.5    Dhingra, V.6
  • 20
    • 63849229179 scopus 로고    scopus 로고
    • The NICE-SUGAR (normoglycaemia in intensive care evaluation and survival using glucose algorithm regulation) study: statistical analysis plan
    • Finfer S, Heritier S. The NICE-SUGAR (normoglycaemia in intensive care evaluation and survival using glucose algorithm regulation) study: statistical analysis plan. Crit Care Resusc. 2009; 11: 46-57.
    • (2009) Crit Care Resusc , vol.11 , pp. 46-57
    • Finfer, S.1    Heritier, S.2
  • 21
    • 0037180768 scopus 로고    scopus 로고
    • The immunopathogenesis of sepsis
    • Cohen J. The immunopathogenesis of sepsis. Nature. 2002; 420: 885-91.
    • (2002) Nature , vol.420 , pp. 885-891
    • Cohen, J.1
  • 22
    • 27744600560 scopus 로고    scopus 로고
    • The immunopathogenesis of sepsis in elderly patients
    • Opal SM, Girard TD, Ely EW. The immunopathogenesis of sepsis in elderly patients. Clin Infect Dis. 2005; 41: S504-12.
    • (2005) Clin Infect Dis , vol.41
    • Opal, S.M.1    Girard, T.D.2    Ely, E.W.3
  • 24
    • 4243332665 scopus 로고    scopus 로고
    • Immunomodulation in sepsis
    • Höflich C, Volk HD. Immunomodulation in sepsis. Chirurg. 2002; 73: 1100-4.
    • (2002) Chirurg , vol.73 , pp. 1100-1104
    • Höflich, C.1    Volk, H.D.2
  • 27
    • 0032734726 scopus 로고    scopus 로고
    • Clinical aspects: from systemic inflammation to 'immunoparalysis
    • Volk HD, Reinke P, Döcke WD. Clinical aspects: from systemic inflammation to 'immunoparalysis'. Chem Immunol. 2000; 74: 162-77.
    • (2000) Chem Immunol , vol.74 , pp. 162-177
    • Volk, H.D.1    Reinke, P.2    Döcke, W.D.3
  • 28
    • 0037397030 scopus 로고    scopus 로고
    • Reversal of immunoparalysis by recombinant human granulocyte-macrophage colony-stimulating factor in patients with severe sepsis
    • Nierhaus A, Montag B, Timmler N, Frings DP, Gutensohn K, Jung R, et al. Reversal of immunoparalysis by recombinant human granulocyte-macrophage colony-stimulating factor in patients with severe sepsis. Intensive Care Med. 2003; 29: 646-51.
    • (2003) Intensive Care Med , vol.29 , pp. 646-651
    • Nierhaus, A.1    Montag, B.2    Timmler, N.3    Frings, D.P.4    Gutensohn, K.5    Jung, R.6
  • 29
    • 0030917203 scopus 로고    scopus 로고
    • Monocyte deactivation in septic patients: restoration by IFN-gamma treatment
    • Döcke WD, Randow F, Syrbe U, Krausch D, Asadullah K, Reinke P, et al. Monocyte deactivation in septic patients: restoration by IFN-gamma treatment. Nat Med. 1997; 3: 678-81.
    • (1997) Nat Med , vol.3 , pp. 678-681
    • Döcke, W.D.1    Randow, F.2    Syrbe, U.3    Krausch, D.4    Asadullah, K.5    Reinke, P.6
  • 30
    • 70349469854 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony-stimulating factor to reverse sepsis-associated immunosuppression: a double-blind, randomized, placebo-controlled multicenter trial
    • Meisel C, Schefold JC, Pschowski R, Baumann T, Hetzger K, Gregor J, et al. Granulocyte-macrophage colony-stimulating factor to reverse sepsis-associated immunosuppression: a double-blind, randomized, placebo-controlled multicenter trial. Am J Respir Crit Care Med. 2009; 180: 640-8.
    • (2009) Am J Respir Crit Care Med , vol.180 , pp. 640-648
    • Meisel, C.1    Schefold, J.C.2    Pschowski, R.3    Baumann, T.4    Hetzger, K.5    Gregor, J.6
  • 31
    • 33947399112 scopus 로고    scopus 로고
    • A novel selective extracorporeal intervention in sepsis: immunoadsorption of endotoxin, interleukin 6, and complement-activating product 5a
    • Schefold JC, von Haehling S, Corsepius M, Pohle C, Kruschke P, Zuckermann H, et al. A novel selective extracorporeal intervention in sepsis: immunoadsorption of endotoxin, interleukin 6, and complement-activating product 5a. Shock. 2007; 28: 418-25.
    • (2007) Shock , vol.28 , pp. 418-425
    • Schefold, J.C.1    von Haehling, S.2    Corsepius, M.3    Pohle, C.4    Kruschke, P.5    Zuckermann, H.6
  • 32
    • 17044394419 scopus 로고    scopus 로고
    • Critical illness polyneuropathy and myopathy in patients with acute respiratory distress syndrome
    • Bercker S, Weber-Carstens S, Deja M, Grimm C, Wolf S, Behse F, et al. Critical illness polyneuropathy and myopathy in patients with acute respiratory distress syndrome. Crit Care Med. 2005; 33: 711-5.
    • (2005) Crit Care Med , vol.33 , pp. 711-715
    • Bercker, S.1    Weber-Carstens, S.2    Deja, M.3    Grimm, C.4    Wolf, S.5    Behse, F.6
  • 34
    • 70350503928 scopus 로고    scopus 로고
    • Intensive care unit-acquired weakness: risk factors and prevention
    • de Jonghe B, Lacherade J, Sharshar T, Outin H. Intensive care unit-acquired weakness: risk factors and prevention. Crit Care Med. 2009; 37: S309-15.
    • (2009) Crit Care Med , vol.37
    • de Jonghe, B.1    Lacherade, J.2    Sharshar, T.3    Outin, H.4
  • 37
    • 34547632886 scopus 로고    scopus 로고
    • Regulation of muscle protein synthesis during sepsis and inflammation
    • Lang CH, Frost RA, Vary TC. Regulation of muscle protein synthesis during sepsis and inflammation. Am J Physiol Endocrinol Metab. 2007; 293: E453-9.
    • (2007) Am J Physiol Endocrinol Metab , vol.293
    • Lang, C.H.1    Frost, R.A.2    Vary, T.C.3
  • 38
    • 0026684174 scopus 로고
    • Sepsis-induced changes in protein synthesis: differential effects on fast-and slow-twitch muscles
    • Vary TC, Kimball SR. Sepsis-induced changes in protein synthesis: differential effects on fast-and slow-twitch muscles. Am J Physiol. 1992; 262: C1513-9.
    • (1992) Am J Physiol , vol.262
    • Vary, T.C.1    Kimball, S.R.2
  • 39
    • 8744292059 scopus 로고    scopus 로고
    • Intensive insulin treatment in critically ill trauma patients normalizes glucose by reducing endogenous glucose production
    • Thorell A, Rooyackers O, Myrenfors P, Soop M, Nygren J, Ljungqvist OH. Intensive insulin treatment in critically ill trauma patients normalizes glucose by reducing endogenous glucose production. J Clin Endocrinol Metab. 2004; 89: 5382-6.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 5382-5386
    • Thorell, A.1    Rooyackers, O.2    Myrenfors, P.3    Soop, M.4    Nygren, J.5    Ljungqvist, O.H.6
  • 41
    • 0037340586 scopus 로고    scopus 로고
    • Insulin resistance in sepsis
    • Carlson GL. Insulin resistance in sepsis. Br J Surg. 2003; 90: 259-60.
    • (2003) Br J Surg , vol.90 , pp. 259-260
    • Carlson, G.L.1
  • 42
    • 1542515271 scopus 로고    scopus 로고
    • Hunterian Lecture: insulin resistance in human sepsis: implications for the nutritional and metabolic care of the critically ill surgical patient
    • Carlson GL. Hunterian Lecture: insulin resistance in human sepsis: implications for the nutritional and metabolic care of the critically ill surgical patient. Ann R Coll Surg Engl. 2004; 86: 75-81.
    • (2004) Ann R Coll Surg Engl , vol.86 , pp. 75-81
    • Carlson, G.L.1
  • 45
    • 0345700727 scopus 로고    scopus 로고
    • Inflammatory cytokines and the risk to develop type 2 diabetes: results of the prospective population-based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study
    • Spranger J, Kroke A, Möhlig M, Hoffmann K, Bergmann MM, Ristow M, et al. Inflammatory cytokines and the risk to develop type 2 diabetes: results of the prospective population-based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study. Diabetes. 2003; 52: 812-7.
    • (2003) Diabetes , vol.52 , pp. 812-817
    • Spranger, J.1    Kroke, A.2    Möhlig, M.3    Hoffmann, K.4    Bergmann, M.M.5    Ristow, M.6
  • 46
    • 42449129727 scopus 로고    scopus 로고
    • Trauma and hemorrhage-induced acute hepatic insulin resistance: dominant role of tumor necrosis factor-alpha
    • Xu J, Kim HT, Ma Y, Zhao L, Zhai L, Kokorina N, et al. Trauma and hemorrhage-induced acute hepatic insulin resistance: dominant role of tumor necrosis factor-alpha. Endocrinology. 2008; 149: 2369-82.
    • (2008) Endocrinology , vol.149 , pp. 2369-2382
    • Xu, J.1    Kim, H.T.2    Ma, Y.3    Zhao, L.4    Zhai, L.5    Kokorina, N.6
  • 47
    • 33845222306 scopus 로고    scopus 로고
    • Sepsis-induced suppression of skeletal muscle translation initiation mediated by tumor necrosis factor alpha
    • Lang CH, Frost RA. Sepsis-induced suppression of skeletal muscle translation initiation mediated by tumor necrosis factor alpha. Metab Clin Exp. 2007; 56: 49-57.
    • (2007) Metab Clin Exp , vol.56 , pp. 49-57
    • Lang, C.H.1    Frost, R.A.2
  • 48
    • 16344385647 scopus 로고    scopus 로고
    • Muscle fiber specific apoptosis and TNF-alpha signaling in sarcopenia are attenuated by life-long calorie restriction
    • Phillips T, Leeuwenburgh C. Muscle fiber specific apoptosis and TNF-alpha signaling in sarcopenia are attenuated by life-long calorie restriction. FASEB J. 2005; 19: 668-70.
    • (2005) FASEB J , vol.19 , pp. 668-670
    • Phillips, T.1    Leeuwenburgh, C.2
  • 49
    • 57349174513 scopus 로고    scopus 로고
    • Anti-TNF treatment reduces rat skeletal muscle wasting in monocrotaline-induced cardiac cachexia
    • Steffen BT, Lees SJ, Booth FW. Anti-TNF treatment reduces rat skeletal muscle wasting in monocrotaline-induced cardiac cachexia. J Appl Physiol. 2008; 105: 1950-8.
    • (2008) J Appl Physiol , vol.105 , pp. 1950-1958
    • Steffen, B.T.1    Lees, S.J.2    Booth, F.W.3
  • 50
    • 0028789750 scopus 로고
    • Interleukin-6 induces proteolysis by activating intracellular proteases (cathepsins B and L, proteasome) in C2C12 myotubes
    • Ebisui C, Tsujinaka T, Morimoto T, Kan K, Iijima S, Yano M, et al. Interleukin-6 induces proteolysis by activating intracellular proteases (cathepsins B and L, proteasome) in C2C12 myotubes. Clin Sci. 1995; 89: 431-9.
    • (1995) Clin Sci , vol.89 , pp. 431-439
    • Ebisui, C.1    Tsujinaka, T.2    Morimoto, T.3    Kan, K.4    Iijima, S.5    Yano, M.6
  • 51
    • 33846875462 scopus 로고    scopus 로고
    • Hormone, cytokine, and nutritional regulation of sepsis-induced increases in atrogin-1 and MuRF1 in skeletal muscle
    • Frost RA, Nystrom GJ, Jefferson LS, Lang CH. Hormone, cytokine, and nutritional regulation of sepsis-induced increases in atrogin-1 and MuRF1 in skeletal muscle. Am J Physiol Endocrinol Metab. 2007; 292: E501-12.
    • (2007) Am J Physiol Endocrinol Metab , vol.292
    • Frost, R.A.1    Nystrom, G.J.2    Jefferson, L.S.3    Lang, C.H.4
  • 52
    • 33751220195 scopus 로고    scopus 로고
    • Cytokine-triggered decreases in levels of phosphorylated eukaryotic initiation factor 4G in skeletal muscle during sepsis
    • Vary TC, Deiter G, Lang CH. Cytokine-triggered decreases in levels of phosphorylated eukaryotic initiation factor 4G in skeletal muscle during sepsis. Shock. 2006; 26: 631-6.
    • (2006) Shock , vol.26 , pp. 631-636
    • Vary, T.C.1    Deiter, G.2    Lang, C.H.3
  • 53
    • 31544435440 scopus 로고    scopus 로고
    • Modulations of muscle protein metabolism by branched-chain amino acids in normal and muscle-atrophying rats
    • Kobayashi H, Kato H, Hirabayashi Y, Murakami H, Suzuki H. Modulations of muscle protein metabolism by branched-chain amino acids in normal and muscle-atrophying rats. J Nutr. 2006; 136: 234S-6.
    • (2006) J Nutr , vol.136
    • Kobayashi, H.1    Kato, H.2    Hirabayashi, Y.3    Murakami, H.4    Suzuki, H.5
  • 54
    • 0029980234 scopus 로고    scopus 로고
    • Effect of a 6-week endurance training programme and branched-chain amino acid supplementation on histomorphometric characteristics of aged human muscle
    • Freyssenet D, Berthon P, Denis C, Barthelemy JC, Guezennec CY, Chatard JC. Effect of a 6-week endurance training programme and branched-chain amino acid supplementation on histomorphometric characteristics of aged human muscle. Arch Physiol Biochem. 1996; 104: 157-62.
    • (1996) Arch Physiol Biochem , vol.104 , pp. 157-162
    • Freyssenet, D.1    Berthon, P.2    Denis, C.3    Barthelemy, J.C.4    Guezennec, C.Y.5    Chatard, J.C.6
  • 56
    • 38549130682 scopus 로고    scopus 로고
    • Supplementation with dietary leucine to a protein-deficient diet suppresses myofibrillar protein degradation in rats
    • Sugawara T, Ito Y, Nishizawa N, Nagasawa T. Supplementation with dietary leucine to a protein-deficient diet suppresses myofibrillar protein degradation in rats. J Nutr Sci Vitaminol. 2007; 53: 552-5.
    • (2007) J Nutr Sci Vitaminol , vol.53 , pp. 552-555
    • Sugawara, T.1    Ito, Y.2    Nishizawa, N.3    Nagasawa, T.4
  • 57
    • 33947687136 scopus 로고    scopus 로고
    • Glucocorticoids and TNFalpha interact cooperatively to mediate sepsis-induced leucine resistance in skeletal muscle
    • Lang CH, Frost RA. Glucocorticoids and TNFalpha interact cooperatively to mediate sepsis-induced leucine resistance in skeletal muscle. Mol Med. 2006; 12: 291-9.
    • (2006) Mol Med , vol.12 , pp. 291-299
    • Lang, C.H.1    Frost, R.A.2
  • 58
    • 0030593939 scopus 로고    scopus 로고
    • Mechanisms of muscle wasting. The role of the ubiquitin-proteasome pathway
    • Mitch WE, Goldberg AL. Mechanisms of muscle wasting. The role of the ubiquitin-proteasome pathway. N Engl J Med. 1996; 335: 1897-905.
    • (1996) N Engl J Med , vol.335 , pp. 1897-1905
    • Mitch, W.E.1    Goldberg, A.L.2
  • 60
    • 4344661699 scopus 로고    scopus 로고
    • Human septic myopathy: induction of cyclooxygenase, heme oxygenase and activation of the ubiquitin proteolytic pathway
    • Rabuel C, Renaud E, Brealey D, Ratajczak P, Damy T, Alves A, et al. Human septic myopathy: induction of cyclooxygenase, heme oxygenase and activation of the ubiquitin proteolytic pathway. Anesthesiology. 2004; 101: 583-90.
    • (2004) Anesthesiology , vol.101 , pp. 583-590
    • Rabuel, C.1    Renaud, E.2    Brealey, D.3    Ratajczak, P.4    Damy, T.5    Alves, A.6
  • 61
    • 34248574060 scopus 로고    scopus 로고
    • Proteasome proteolytic activity in skeletal muscle is increased in patients with sepsis
    • Klaude M, Fredriksson K, Tjäder I, Hammarqvist F, Ahlman B, Rooyackers O, et al. Proteasome proteolytic activity in skeletal muscle is increased in patients with sepsis. Clin Sci. 2007; 112: 499-506.
    • (2007) Clin Sci , vol.112 , pp. 499-506
    • Klaude, M.1    Fredriksson, K.2    Tjäder, I.3    Hammarqvist, F.4    Ahlman, B.5    Rooyackers, O.6
  • 62
    • 0020678196 scopus 로고
    • Stimulation of muscle protein degradation and prostaglandin E2 release by leukocytic pyrogen (interleukin-1). A mechanism for the increased degradation of muscle proteins during fever
    • Baracos V, Rodemann HP, Dinarello CA, Goldberg AL. Stimulation of muscle protein degradation and prostaglandin E2 release by leukocytic pyrogen (interleukin-1). A mechanism for the increased degradation of muscle proteins during fever. N Engl J Med. 1983; 308: 553-8.
    • (1983) N Engl J Med , vol.308 , pp. 553-558
    • Baracos, V.1    Rodemann, H.P.2    Dinarello, C.A.3    Goldberg, A.L.4
  • 63
    • 0023835222 scopus 로고
    • Evidence that cathepsin B contributes to skeletal muscle protein breakdown during sepsis
    • Hummel RP, James JH, Warner BW, Hasselgren PO, Fischer JE. Evidence that cathepsin B contributes to skeletal muscle protein breakdown during sepsis. Arch Surg. 1988; 123: 221-4.
    • (1988) Arch Surg , vol.123 , pp. 221-224
    • Hummel, R.P.1    James, J.H.2    Warner, B.W.3    Hasselgren, P.O.4    Fischer, J.E.5
  • 64
    • 0029883726 scopus 로고    scopus 로고
    • Muscle wasting in a rat model of long-lasting sepsis results from the activation of lysosomal, Ca2+ -activated, and ubiquitin-proteasome proteolytic pathways
    • Voisin L, Breuillé D, Combaret L, Pouyet C, Taillandier D, Aurousseau E, et al. Muscle wasting in a rat model of long-lasting sepsis results from the activation of lysosomal, Ca2+ -activated, and ubiquitin-proteasome proteolytic pathways. J Clin Invest. 1996; 97: 1610-7.
    • (1996) J Clin Invest , vol.97 , pp. 1610-1617
    • Voisin, L.1    Breuillé, D.2    Combaret, L.3    Pouyet, C.4    Taillandier, D.5    Aurousseau, E.6
  • 65
    • 0032514704 scopus 로고    scopus 로고
    • Role of calpain in skeletal-muscle protein degradation
    • Huang J, Forsberg NE. Role of calpain in skeletal-muscle protein degradation. Proc Natl Acad Sci USA. 1998; 95: 12100-5.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 12100-12105
    • Huang, J.1    Forsberg, N.E.2
  • 66
    • 85047693596 scopus 로고    scopus 로고
    • Activation of caspase-3 is an initial step triggering accelerated muscle proteolysis in catabolic conditions
    • Du J, Wang X, Miereles C, Bailey JL, Debigare R, Zheng B, et al. Activation of caspase-3 is an initial step triggering accelerated muscle proteolysis in catabolic conditions. J Clin Invest. 2004; 113: 115-23.
    • (2004) J Clin Invest , vol.113 , pp. 115-123
    • Du, J.1    Wang, X.2    Miereles, C.3    Bailey, J.L.4    Debigare, R.5    Zheng, B.6
  • 67
    • 0024166076 scopus 로고
    • Some properties of the millimolar Ca2 + -dependent proteinase from bovine cardiac muscle
    • Tan FC, Goll DE, Otsuka Y. Some properties of the millimolar Ca2 + -dependent proteinase from bovine cardiac muscle. J Mol Cell Cardiol. 1988; 20: 983-97.
    • (1988) J Mol Cell Cardiol , vol.20 , pp. 983-997
    • Tan, F.C.1    Goll, D.E.2    Otsuka, Y.3
  • 68
    • 36448968532 scopus 로고    scopus 로고
    • FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells
    • Zhao J, Brault JJ, Schild A, Cao P, Sandri M, Schiaffino S, et al. FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells. Cell Metab. 2007; 6: 472-83.
    • (2007) Cell Metab , vol.6 , pp. 472-483
    • Zhao, J.1    Brault, J.J.2    Schild, A.3    Cao, P.4    Sandri, M.5    Schiaffino, S.6
  • 69
    • 11144356337 scopus 로고    scopus 로고
    • Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy
    • Sandri M, Sandri C, Gilbert A, Skurk C, Calabria E, Picard A, et al. Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy. Cell. 2004; 117: 399-412.
    • (2004) Cell , vol.117 , pp. 399-412
    • Sandri, M.1    Sandri, C.2    Gilbert, A.3    Skurk, C.4    Calabria, E.5    Picard, A.6
  • 70
    • 0035941020 scopus 로고    scopus 로고
    • Identification of ubiquitin ligases required for skeletal muscle atrophy
    • Bodine SC, Latres E, Baumhueter S, Lai VK, Nunez L, Clarke BA, et al. Identification of ubiquitin ligases required for skeletal muscle atrophy. Science. 2001; 294: 1704-8.
    • (2001) Science , vol.294 , pp. 1704-1708
    • Bodine, S.C.1    Latres, E.2    Baumhueter, S.3    Lai, V.K.4    Nunez, L.5    Clarke, B.A.6
  • 72
    • 35548973391 scopus 로고    scopus 로고
    • The E3 Ligase MuRF1 degrades myosin heavy chain protein in dexamethasone-treated skeletal muscle
    • Clarke BA, Drujan D, Willis MS, Murphy LO, Corpina RA, Burova E, et al. The E3 Ligase MuRF1 degrades myosin heavy chain protein in dexamethasone-treated skeletal muscle. Cell Metab. 2007; 6: 376-85.
    • (2007) Cell Metab , vol.6 , pp. 376-385
    • Clarke, B.A.1    Drujan, D.2    Willis, M.S.3    Murphy, L.O.4    Corpina, R.A.5    Burova, E.6
  • 73
    • 67449132363 scopus 로고    scopus 로고
    • During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation
    • Cohen S, Brault JJ, Gygi SP, Glass DJ, Valenzuela DM, Gartner C, et al. During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation. J Cell Biol. 2009; 185: 1083-95.
    • (2009) J Cell Biol , vol.185 , pp. 1083-1095
    • Cohen, S.1    Brault, J.J.2    Gygi, S.P.3    Glass, D.J.4    Valenzuela, D.M.5    Gartner, C.6
  • 76
    • 77951464177 scopus 로고    scopus 로고
    • MAFbx/Atrogin-1 expression is a poor index of muscle proteolysis
    • Attaix D, Baracos VE. MAFbx/Atrogin-1 expression is a poor index of muscle proteolysis. Curr Opin Clin Nutr Metab. 2010; 13: 223-4.
    • (2010) Curr Opin Clin Nutr Metab , vol.13 , pp. 223-224
    • Attaix, D.1    Baracos, V.E.2
  • 77
    • 70350520376 scopus 로고    scopus 로고
    • Intensive care unit-acquired weakness: framing the topic
    • Vincent J, Norrenberg M. Intensive care unit-acquired weakness: framing the topic. Crit Care Med. 2009; 37: S296-8.
    • (2009) Crit Care Med , vol.37
    • Vincent, J.1    Norrenberg, M.2
  • 84
    • 34548292962 scopus 로고    scopus 로고
    • Respiratory weakness is associated with limb weakness and delayed weaning in critical illness
    • De Jonghe B, Bastuji-Garin S, Durand M, Malissin I, Rodrigues P, Cerf C, et al. Respiratory weakness is associated with limb weakness and delayed weaning in critical illness. Crit Care Med. 2007; 35: 2007-15.
    • (2007) Crit Care Med , vol.35 , pp. 2007-2015
    • de Jonghe, B.1    Bastuji-Garin, S.2    Durand, M.3    Malissin, I.4    Rodrigues, P.5    Cerf, C.6
  • 85
    • 0036667412 scopus 로고    scopus 로고
    • Long-term outcomes after critical illness
    • Herridge MS. Long-term outcomes after critical illness. Curr Opin Crit Care. 2002; 8: 331-6.
    • (2002) Curr Opin Crit Care , vol.8 , pp. 331-336
    • Herridge, M.S.1
  • 86
    • 70350510281 scopus 로고    scopus 로고
    • Legacy of intensive care unit-acquired weakness
    • Herridge MS. Legacy of intensive care unit-acquired weakness. Crit Care Med. 2009; 37: S457-61.
    • (2009) Crit Care Med , vol.37
    • Herridge, M.S.1
  • 87
    • 0026050521 scopus 로고
    • Interobserver agreement in the assessment of muscle strength and functional abilities in Guillain-Barré syndrome
    • Kleyweg RP, van der Meché FG, Schmitz PI. Interobserver agreement in the assessment of muscle strength and functional abilities in Guillain-Barré syndrome. Muscle Nerve. 1991; 14: 1103-9.
    • (1991) Muscle Nerve , vol.14 , pp. 1103-1109
    • Kleyweg, R.P.1    van der Meché, F.G.2    Schmitz, P.I.3
  • 88
    • 77952265533 scopus 로고    scopus 로고
    • Presentation and management of ICU myopathy and neuropathy
    • Jan 13. Available from, Accessed 4 Feb 2010
    • Latronico N, Rasulo FA. Presentation and management of ICU myopathy and neuropathy. Curr Opin Crit Care [Internet]. 2010 Jan 13. Available from: http://www. ncbi. nlm. nih. gov/pubmed/20075723. Accessed 4 Feb 2010.
    • (2010) Curr Opin Crit Care [Internet]
    • Latronico, N.1    Rasulo, F.A.2
  • 89
    • 69349102298 scopus 로고    scopus 로고
    • Nonexcitable muscle membrane predicts intensive care unit-acquired paresis in mechanically ventilated, sedated patients
    • Weber-Carstens S, Koch S, Spuler S, Spies CD, Bubser F, Wernecke KD, et al. Nonexcitable muscle membrane predicts intensive care unit-acquired paresis in mechanically ventilated, sedated patients. Crit Care Med. 2009; 37: 2632-7.
    • (2009) Crit Care Med , vol.37 , pp. 2632-2637
    • Weber-Carstens, S.1    Koch, S.2    Spuler, S.3    Spies, C.D.4    Bubser, F.5    Wernecke, K.D.6
  • 90
    • 67649219652 scopus 로고    scopus 로고
    • Early use of polymyxin B hemoperfusion in abdominal septic shock: the EUPHAS randomized controlled trial
    • Cruz DN, Antonelli M, Fumagalli R, Foltran F, Brienza N, Donati A, et al. Early use of polymyxin B hemoperfusion in abdominal septic shock: the EUPHAS randomized controlled trial. JAMA. 2009; 301: 2445-52.
    • (2009) Jama , vol.301 , pp. 2445-2452
    • Cruz, D.N.1    Antonelli, M.2    Fumagalli, R.3    Foltran, F.4    Brienza, N.5    Donati, A.6
  • 92
    • 66449127204 scopus 로고    scopus 로고
    • Organ crosstalk in critically ill patients: hemofiltration and immunomodulation in sepsis
    • Schefold JC, Hasper D, Jörres A. Organ crosstalk in critically ill patients: hemofiltration and immunomodulation in sepsis. Blood Purif. 2009; 28: 116-23.
    • (2009) Blood Purif , vol.28 , pp. 116-123
    • Schefold, J.C.1    Hasper, D.2    Jörres, A.3
  • 93
    • 44949263778 scopus 로고    scopus 로고
    • Apheresis in patients with severe sepsis and multi organ dysfunction syndrome
    • Stegmayr B. Apheresis in patients with severe sepsis and multi organ dysfunction syndrome. Transfus Apher Sci. 2008; 38: 203-8.
    • (2008) Transfus Apher Sci , vol.38 , pp. 203-208
    • Stegmayr, B.1
  • 95
    • 65849187703 scopus 로고    scopus 로고
    • Early physical and occupational therapy in mechanically ventilated, critically ill patients: a randomised controlled trial
    • Schweickert WD, Pohlman MC, Pohlman AS, Nigos C, Pawlik AJ, Esbrook CL, et al. Early physical and occupational therapy in mechanically ventilated, critically ill patients: a randomised controlled trial. Lancet. 2009; 373: 1874-82.
    • (2009) Lancet , vol.373 , pp. 1874-1882
    • Schweickert, W.D.1    Pohlman, M.C.2    Pohlman, A.S.3    Nigos, C.4    Pawlik, A.J.5    Esbrook, C.L.6
  • 96
    • 77949905301 scopus 로고    scopus 로고
    • Electrical muscle stimulation preserves the muscle mass of critically ill patients: a randomized study
    • Gerovasili V, Stefanidis K, Vitzilaios K, Karatzanos E, Politis P, Koroneos A, et al. Electrical muscle stimulation preserves the muscle mass of critically ill patients: a randomized study. Crit Care. 2009; 13: R161.
    • (2009) Crit Care , vol.13
    • Gerovasili, V.1    Stefanidis, K.2    Vitzilaios, K.3    Karatzanos, E.4    Politis, P.5    Koroneos, A.6
  • 97
    • 67649516130 scopus 로고    scopus 로고
    • Neuromuscular electrical stimulation reduces skeletal muscle protein degradation and stimulates insulin-like growth factors in an age-and current-dependent manner: a randomized, controlled clinical trial in major abdominal surgical patients
    • Strasser EM, Stättner S, Karner J, Klimpfinger M, Freynhofer M, Zaller V, et al. Neuromuscular electrical stimulation reduces skeletal muscle protein degradation and stimulates insulin-like growth factors in an age-and current-dependent manner: a randomized, controlled clinical trial in major abdominal surgical patients. Ann Surg. 2009; 249: 738-43.
    • (2009) Ann Surg , vol.249 , pp. 738-743
    • Strasser, E.M.1    Stättner, S.2    Karner, J.3    Klimpfinger, M.4    Freynhofer, M.5    Zaller, V.6
  • 98
    • 17644386216 scopus 로고    scopus 로고
    • Insulin therapy protects the central and peripheral nervous system of intensive care patients
    • van den Berghe G, Schoonheydt K, Becx P, Bruyninckx F, Wouters PJ. Insulin therapy protects the central and peripheral nervous system of intensive care patients. Neurology. 2005; 64: 1348-53.
    • (2005) Neurology , vol.64 , pp. 1348-1353
    • van den Berghe, G.1    Schoonheydt, K.2    Becx, P.3    Bruyninckx, F.4    Wouters, P.J.5
  • 99
    • 33847609717 scopus 로고    scopus 로고
    • Impact of intensive insulin therapy on neuromuscular complications and ventilator dependency in the medical intensive care unit
    • Hermans G, Wilmer A, Meersseman W, Milants I, Wouters PJ, Bobbaers H, et al. Impact of intensive insulin therapy on neuromuscular complications and ventilator dependency in the medical intensive care unit. Am J Respir Crit Care Med. 2007; 175: 480-9.
    • (2007) Am J Respir Crit Care Med , vol.175 , pp. 480-489
    • Hermans, G.1    Wilmer, A.2    Meersseman, W.3    Milants, I.4    Wouters, P.J.5    Bobbaers, H.6
  • 101
    • 0036789446 scopus 로고    scopus 로고
    • Quadriplegic areflexic ICU illness: selective thick filament loss and normal nerve histology
    • Sander HW, Golden M, Danon MJ. Quadriplegic areflexic ICU illness: selective thick filament loss and normal nerve histology. Muscle Nerve. 2002; 26: 499-505.
    • (2002) Muscle Nerve , vol.26 , pp. 499-505
    • Sander, H.W.1    Golden, M.2    Danon, M.J.3
  • 103
    • 77953633892 scopus 로고    scopus 로고
    • Risk factors in Critical illness myopathy (CIM) during the early course of critical illness: a prospective observational study
    • Weber-Carstens S, Deja M, Koch S, Spranger J, Bubser F, Wernecke K, et al. Risk factors in Critical illness myopathy (CIM) during the early course of critical illness: a prospective observational study. Crit Care. 2010; 14: R119.
    • (2010) Crit Care , vol.14
    • Weber-Carstens, S.1    Deja, M.2    Koch, S.3    Spranger, J.4    Bubser, F.5    Wernecke, K.6
  • 105
    • 79951790926 scopus 로고    scopus 로고
    • Critical illness myopathy is frequent-accompanying neuropathy protracts ICU discharge
    • (in press)
    • Koch S, Spuler S, Deja M, Bierbrauer J, Dimroth A, Behse F, et al. Critical illness myopathy is frequent-accompanying neuropathy protracts ICU discharge. JNNP. 2010 (in press).
    • (2010) JNNP
    • Koch, S.1    Spuler, S.2    Deja, M.3    Bierbrauer, J.4    Dimroth, A.5    Behse, F.6
  • 106
    • 0033950673 scopus 로고    scopus 로고
    • Acute quadriplegia and loss of muscle myosin in patients treated with nondepolarizing neuromuscular blocking agents and corticosteroids: mechanisms at the cellular and molecular levels
    • Larsson L, Li X, Edström L, Eriksson LI, Zackrisson H, Argentini C, et al. Acute quadriplegia and loss of muscle myosin in patients treated with nondepolarizing neuromuscular blocking agents and corticosteroids: mechanisms at the cellular and molecular levels. Crit Care Med. 2000; 28: 34-45.
    • (2000) Crit Care Med , vol.28 , pp. 34-45
    • Larsson, L.1    Li, X.2    Edström, L.3    Eriksson, L.I.4    Zackrisson, H.5    Argentini, C.6
  • 107
    • 0029919453 scopus 로고    scopus 로고
    • Acute myopathy of intensive care: clinical, electromyographic, and pathological aspects
    • Lacomis D, Giuliani MJ, van Cott A, Kramer DJ. Acute myopathy of intensive care: clinical, electromyographic, and pathological aspects. Ann Neurol. 1996; 40: 645-54.
    • (1996) Ann Neurol , vol.40 , pp. 645-654
    • Lacomis, D.1    Giuliani, M.J.2    van Cott, A.3    Kramer, D.J.4
  • 110
    • 0026455064 scopus 로고
    • Acute quadriplegic myopathy: a complication of treatment with steroids, nondepolarizing blocking agents, or both
    • Hirano M, Ott BR, Raps EC, Minetti C, Lennihan L, Libbey NP, et al. Acute quadriplegic myopathy: a complication of treatment with steroids, nondepolarizing blocking agents, or both. Neurology. 1992; 42: 2082-7.
    • (1992) Neurology , vol.42 , pp. 2082-2087
    • Hirano, M.1    Ott, B.R.2    Raps, E.C.3    Minetti, C.4    Lennihan, L.5    Libbey, N.P.6
  • 112
    • 0031034910 scopus 로고    scopus 로고
    • Acute quadriplegic myopathy: analysis of myosin isoforms and evidence for calpain-mediated proteolysis
    • Showalter CJ, Engel AG. Acute quadriplegic myopathy: analysis of myosin isoforms and evidence for calpain-mediated proteolysis. Muscle Nerve. 1997; 20: 316-22.
    • (1997) Muscle Nerve , vol.20 , pp. 316-322
    • Showalter, C.J.1    Engel, A.G.2
  • 113
    • 0018316084 scopus 로고
    • Acute myopathy with selective lysis of myosin filaments
    • Sher JH, Shafiq SA, Schutta HS. Acute myopathy with selective lysis of myosin filaments. Neurology. 1979; 29: 100-6.
    • (1979) Neurology , vol.29 , pp. 100-106
    • Sher, J.H.1    Shafiq, S.A.2    Schutta, H.S.3
  • 114
  • 115
    • 0035064684 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced diaphragmatic contractile dysfunction and sarcolemmal injury in mice lacking the neuronal nitric oxide synthase
    • Comtois AS, Barreiro E, Huang PL, Marette A, Perrault M, Hussain SN. Lipopolysaccharide-induced diaphragmatic contractile dysfunction and sarcolemmal injury in mice lacking the neuronal nitric oxide synthase. Am J Respir Crit Care Med. 2001; 163: 977-82.
    • (2001) Am J Respir Crit Care Med , vol.163 , pp. 977-982
    • Comtois, A.S.1    Barreiro, E.2    Huang, P.L.3    Marette, A.4    Perrault, M.5    Hussain, S.N.6
  • 116
    • 0037080717 scopus 로고    scopus 로고
    • Mechanical ventilation protects against diaphragm injury in sepsis: interaction of oxidative and mechanical stresses
    • Ebihara S, Hussain SNA, Danialou G, Cho W, Gottfried SB, Petrof BJ. Mechanical ventilation protects against diaphragm injury in sepsis: interaction of oxidative and mechanical stresses. Am J Respir Crit Care Med. 2002; 165: 221-8.
    • (2002) Am J Respir Crit Care Med , vol.165 , pp. 221-228
    • Ebihara, S.1    Hussain, S.N.A.2    Danialou, G.3    Cho, W.4    Gottfried, S.B.5    Petrof, B.J.6
  • 119
    • 0035159587 scopus 로고    scopus 로고
    • Superoxide, hydroxyl radical, and hydrogen peroxide effects on single-diaphragm fiber contractile apparatus
    • Callahan LA, She ZW, Nosek TM. Superoxide, hydroxyl radical, and hydrogen peroxide effects on single-diaphragm fiber contractile apparatus. J Appl Physiol. 2001; 90: 45-54.
    • (2001) J Appl Physiol , vol.90 , pp. 45-54
    • Callahan, L.A.1    She, Z.W.2    Nosek, T.M.3
  • 121
    • 0037102398 scopus 로고    scopus 로고
    • Respiratory and limb muscle weakness induced by tumor necrosis factor-alpha: involvement of muscle myofilaments
    • Reid MB, Lännergren J, Westerblad H. Respiratory and limb muscle weakness induced by tumor necrosis factor-alpha: involvement of muscle myofilaments. Am J Respir Crit Care Med. 2002; 166: 479-84.
    • (2002) Am J Respir Crit Care Med , vol.166 , pp. 479-484
    • Reid, M.B.1    Lännergren, J.2    Westerblad, H.3
  • 122
    • 41549114074 scopus 로고    scopus 로고
    • TNF-alpha acts via TNFR1 and muscle-derived oxidants to depress myofibrillar force in murine skeletal muscle
    • Hardin BJ, Campbell KS, Smith JD, Arbogast S, Smith J, Moylan JS, et al. TNF-alpha acts via TNFR1 and muscle-derived oxidants to depress myofibrillar force in murine skeletal muscle. J Appl Physiol. 2008; 104: 694-9.
    • (2008) J Appl Physiol , vol.104 , pp. 694-699
    • Hardin, B.J.1    Campbell, K.S.2    Smith, J.D.3    Arbogast, S.4    Smith, J.5    Moylan, J.S.6
  • 123
    • 33751186701 scopus 로고    scopus 로고
    • Derangements in mitochondrial metabolism in intercostal and leg muscle of critically ill patients with sepsis-induced multiple organ failure
    • Fredriksson K, Hammarqvist F, Strigård K, Hultenby K, Ljungqvist O, Wernerman J, et al. Derangements in mitochondrial metabolism in intercostal and leg muscle of critically ill patients with sepsis-induced multiple organ failure. Am J Physiol Endocrinol Metab. 2006; 291: E1044-50.
    • (2006) Am J Physiol Endocrinol Metab , vol.291
    • Fredriksson, K.1    Hammarqvist, F.2    Strigård, K.3    Hultenby, K.4    Ljungqvist, O.5    Wernerman, J.6
  • 124
    • 84862865537 scopus 로고    scopus 로고
    • Ethical guidelines for authorship and publishing in the Journal of Cachexia, Sarcopenia and Muscle
    • von Haehling S, Morley JE, Coats AJ, Anker SD. Ethical guidelines for authorship and publishing in the Journal of Cachexia, Sarcopenia and Muscle. J Cachexia Sarcopenia Muscle 2010; 1: 7-8.
    • (2010) J Cachexia Sarcopenia Muscle , vol.1 , pp. 7-8
    • von Haehling, S.1    Morley, J.E.2    Coats, A.J.3    Anker, S.D.4


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