Improved immune responses in mice using the novel chitosan adjuvant ViscoGel, with a Haemophilus influenzae type b glycoconjugate vaccine

Vaccine

Volumn 29, Issue 48, 2011, Pages 8965-8973

  Neimert Andersson, Theresa ^a,b   Hällgren, Anne Charlotte ^b   Andersson, Mats ^b   Langebäck, Joakim ^b   Zettergren, Louise ^b   Nilsen Nygaard, Julie ^c   Draget, Kurt Ingar ^c   van Hage, Marianne ^a   Lindberg, Alf ^b   Gafvelin, Guro ^a,b   Grönlund, Hans ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b Viscogel AB   (Sweden)

^c NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

Author keywords

Adjuvant; Chitosan; Immune response; Neutrophils; Vaccination

Indexed keywords

ACETIC ACID DERIVATIVE; CHITOSAN; GAMMA INTERFERON; HAEMOPHILUS INFLUENZAE VACCINE; INTERLEUKIN 17; INTERLEUKIN 4; INTERLEUKIN 6;

ANIMAL EXPERIMENT; ANTIBODY TITER; ARTICLE; CONTROLLED STUDY; DEACETYLATION; FEMALE; HAEMOPHILUS INFLUENZAE; IMMUNE RESPONSE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; TH1 CELL; TH2 CELL; VACCINATION;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES, BACTERIAL; CELLS, CULTURED; CHITOSAN; CYTOKINES; FEMALE; HAEMOPHILUS VACCINES; IMMUNITY, CELLULAR; IMMUNITY, HUMORAL; METHYLMETHACRYLATES; MICE; MICE, INBRED BALB C; NEUTROPHILS; SPLEEN; VACCINES, CONJUGATE;

EID: 82455192374     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2011.09.041     Document Type: Article

References (35)

1. Gherardi R., Coquet M., Cherin P., Belec L., Moretto P., Dreyfus P., et al. Macrophagic myofasciitis lesions assess long-term persistence of vaccine-derived aluminium hydroxide in muscle. Brain 2001, 124(September (Pt 9)):1821-1831.
2. Kool M., Pétrilli V., De Smedt T., Rolaz A., Hammad H., van Nimwegen M., et al. Cutting edge: alum adjuvant stimulates inflammatory dendritic cells through activation of the NALP3 inflammasome. J Immunol 2008, 181(September (6)):3755-3759.
3. Kool M., Soullié T., van Nimwegen M., Willart M.A., Muskens F., Jung S., et al. Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells. J Exp Med 2008, 205(April (4)):869-882.
4. Flach T.L., Ng G., Hari A., Desrosiers M.D., Zhang P., Ward S.M., et al. Alum interaction with dendritic cell membrane lipids is essential for its adjuvanticity. Nat Med 2011, 17(April (4)):479-487.
5. Pichichero M. Improving vaccine delivery using novel adjuvant systems. Hum Vaccin 2008, 4(July-August (4)):262-270.
6. Tagliabue A., Rappuoli R. Vaccine adjuvants: the dream becomes real. Hum Vaccin 2008, 4(September-October (5)):347-349.
7. Mbow M.L., De Gregorio E., Valiante N.M., Rappuoli R. New adjuvants for human vaccines. Curr Opin Immunol 2010, 22(June (3)):411-416.
8. Lingnau K., Riedl K., von Gabain A. IC31 and IC30, novel types of vaccine adjuvant based on peptide delivery systems. Expert Rev Vaccines 2007, 6(October (5)):741-746.
9. Petrovsky N., Cooper P.D. Carbohydrate-based immune adjuvants. Expert Rev Vaccines 2011, 10(April (4)):523-537.
10. Grönlund H., Vrtala S., Wiedermann U., Dekan G., Kraft D., Valenta R., et al. Carbohydrate-based particles: a new adjuvant for allergen-specific immunotherapy. Immunology 2002, 107(December (4)):523-529.
11. Thunberg S., Neimert-Andersson T., Cheng Q., Wermeling F., Bergström U., Swedin L., et al. Prolonged antigen-exposure with carbohydrate particle based vaccination prevents allergic immune responses in sensitized mice. Allergy 2009, 64(June (6)):919-926.
12. Fraser C., Diener K., Brown M., Hayball J. Improving vaccines by incorporating immunological coadjuvants. Expert Rev Vaccines 2007, 6(August (4)):559-578.
13. Guy B. The perfect mix: recent progress in adjuvant research. Nat Rev Microbiol 2007, 5(July (7)):505-517.
14. Cerundolo V., Silk J., Masri S., Salio M. Harnessing invariant NKT cells in vaccination strategies. Nat Rev Immunol 2009, 9(January (1)):28-38.
15. Pandey M., Batzloff M., Good M. Mechanism of protection induced by group A Streptococcus vaccine candidate J8-DT: contribution of B and T-cells towards protection. PLoS One 2009, 4(4):e5147.
16. Ravi Kumar M.N.V. A review of chitin and chitosan applications. React Funct Polym 2000, 46:1-27.
17. Arca H., Günbeyaz M., Senel S. Chitosan-based systems for the delivery of vaccine antigens. Expert Rev Vaccines 2009, 8(July (7)):937-953.
18. Singla A., Chawla M. Chitosan: some pharmaceutical and biological aspects - an update. J Pharm Pharmacol 2001, 53(August (8)):1047-1067.
19. Vårum K.M., Ottoy M.H., Smidsrod O. Water-solubility of partially N-acetylated chitosans as a function of pH: effect of chemical composition and depolymerisation. Carbohyd Polym 1994, 25:65-70.
20. Tomihata K., Ikada Y. In vitro and in vivo degradation of films of chitin and its deacetylated derivatives. Biomaterials 1997, 18(April (7)):567-575.
21. Sturgess A.W., Rush K., Charbonneau R.J., Lee J.I., West D.J., Sitrin R.D., et al. Haemophilus influenzae type b conjugate vaccine stability: catalytic depolymerization of PRP in the presence of aluminum hydroxide. Vaccine 1999, 17(March (9-10)):1169-1178.
22. Eskola J., Olander R.M., Hovi T., Litmanen L., Peltola S., Käyhty H. Randomised trial of the effect of co-administration with acellular pertussis DTP vaccine on immunogenicity of Haemophilus influenzae type b conjugate vaccine. Lancet 1996, 348(December (21-28)):1688-1692. (9043).
23. Neimert-Andersson T., Thunberg S., Swedin L., Wiedermann U., Jacobsson-Ekman G., Dahlén S., et al. Carbohydrate-based particles reduce allergic inflammation in a mouse model for cat allergy. Allergy 2008, 63(May (5)):518-526.
24. Calabro S., Tortoli M., Baudner B.C., Pacitto A., Cortese M., òHagan D.T., et al. Vaccine adjuvants alum and MF59 induce rapid recruitment of neutrophils and monocytes that participate in antigen transport to draining lymph nodes. Vaccine 2011, 29(February (9)):1812-1823.
25. Rose C.E., Lannigan J.A., Kim P., Lee J.J., Fu S.M., Sung S.S. Murine lung eosinophil activation and chemokine production in allergic airway inflammation. Cell Mol Immunol 2010, 7(September (5)):361-374.
26. Zaharoff D., Rogers C., Hance K., Schlom J., Greiner J. Chitosan solution enhances both humoral and cell-mediated immune responses to subcutaneous vaccination. Vaccine 2007, 25(March (11)):2085-2094.
27. Park C., Gabrielson N., Pack D., Jamison R., Wagoner Johnson A. The effect of chitosan on the migration of neutrophil-like HL60 cells, mediated by IL-8. Biomaterials 2009, 30(February (4)):436-444.
28. Simard P., Galarneau H., Marois S., Rusu D., Hoemann C., Poubelle P., et al. Neutrophils exhibit distinct phenotypes toward chitosans with different degrees of deacetylation: implications for cartilage repair. Arthritis Res Ther 2009, 11(3):R74.
29. Bennouna S., Bliss S., Curiel T., Denkers E. Cross-talk in the innate immune system: neutrophils instruct recruitment and activation of dendritic cells during microbial infection. J Immunol 2003, 171(December (11)):6052-6058.
30. van Gisbergen K., Sanchez-Hernandez M., Geijtenbeek T., van Kooyk Y. Neutrophils mediate immune modulation of dendritic cells through glycosylation-dependent interactions between Mac-1 and DC-SIGN. J Exp Med 2005, 201(April (8)):1281-1292.
31. van Gisbergen K., Geijtenbeek T., van Kooyk Y. Close encounters of neutrophils and DCs. Trends Immunol 2005, 26(December (12)):626-631.
32. Abi Abdallah D.S., Egan C.E., Butcher B.A., Denkers E.Y. Mouse neutrophils are professional antigen-presenting cells programmed to instruct Th1 and Th17 T-cell differentiation. Int Immunol 2011, 23(May (5)):317-326.
33. Da Silva C., Hartl D., Liu W., Lee C., Elias J. TLR-2 and IL-17A in chitin-induced macrophage activation and acute inflammation. J Immunol 2008, 181(September (6)):4279-4286.
34. Koller B., Müller-Wiefel A.S., Rupec R., Korting H.C., Ruzicka T. Chitin modulates innate immune responses of keratinocytes. PLoS One 2011, 6(2):e16594.
35. Eskola J. Foresight in medicine: current challenges with Haemophilus influenzae type b conjugate vaccines. J Intern Med 2010, 267(March (3)):241-250.